Final year PhD student Dilip Thomas has been awarded a travel fellowship by the European Molecular Biology Organization (EMBO), to advance his research in in the area of vascular repair and regeneration.
Aug 04 2015 Posted: 14:53 IST

Final year PhD student Dilip Thomas has been awarded a travel fellowship by the European Molecular Biology Organization (EMBO), to advance his research in the area of vascular repair and regeneration.

Dilip is carrying out his PhD at NUI Galway, supervised by Professor Abhay Pandit and Professor Timothy O’Brien of CÚRAM, the Science Foundation Ireland funded Centre for Research in Medical Devices. 

Dilip’s project looks specifically at the development of a functionalised stem cell delivery platform for critical limb ischemia. Critical limb ischemia is a serious form of peripheral arterial disease and is caused by atherosclerosis, the hardening and narrowing of the arteries over time due to the build-up of fatty deposits called plaque and is a chronic condition that results in severe pain, even while resting. Complications of poor circulation can include sores and wounds that won't heal and complications of critical limb ischemia can result in amputation.

The research goal at CÚRAM is to engineer a unique ‘finger-print’ microenvironment, also called ‘niche’, for the modulation of stem cell behaviour to promote new blood vessel formation. The long-term goal is to translate pre-clinical success to a viable therapeutic alternative for the treatment of ‘no option’ critical limb ischemia patients to allow amputation-free survival.

The fellowship opportunity at Professor Marchetti-Deschmann’s analytical laboratory, Technical University of Vienna, Austria will help dissect the key molecular factors and events that drive tissue repair and regeneration with help of state-of-the-art tissue imaging mass-spectrometers.

EMBO is an organisation of more than 1,700 leading researchers that promotes excellence in the life sciences. The major goals of the organisation are to support talented researchers at all stages of their careers, stimulate the exchange of scientific information, and help build a European research environment where scientists can achieve their best work.

“The EMBO fellowship is a great step in Dilip’s career as a researcher and reflects the high standard of research being carried out at CÚRAM in ‘smart’ medical device development at all levels” said Professor Abhay Pandit, Director of CÚRAM. “The key aim of our work is to radically improve health outcomes for patients suffering from chronic illnesses, including CLI.”

CÚRAM is a national research centre advancing R&D in the medical device sector. Supported by Science Foundation Ireland and industry partners, CÚRAM enhances Ireland's standing as a major hub for the global medical devices industry.

ENDS

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