SCIENTIFIC PUBLICATIONS (ADRIENNE GORMAN)

RESEARCH ARTICLES

Yao L, Wang S, Cui W, Sherlock R, O’Connell C, Damodaran G, Gorman A, Windebank A, Pandit A (2009) Effect of functionalised micropatterned PLGA on guided neurite growth. ACTA Biomater 5, 580-588

Szegezdi E, Reed Herbert K, Kavanagh ET, Samali A and Gorman AM (2008) Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim. J Cell Mol Med 12, 2482-2496

Read DE, Reed Herbert K, Gorman AM (2008) Heat shock enhances NGF-induced neurite elongation which is not mediated by Hsp25 in PC12 cells. Brain Res 1221, 14-23

Kavanagh ET, Loughlin JP, Herbert KR, Dockery P, Samali A, Doyle KM, and Gorman AM (2006) Functionality of NGF-protected PC12 cells following exposure to 6-hydroxydopamine. Biochem Biophys Res Commun 351, 890-895  (For PDF click here)

Ní Chonghaile T, Concannon CG, Szegezdi E, Gorman AM and Samali A (2006) Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL. Apoptosis 11, 1247-1255 (For PDF click here)

O’Driscoll CM, Gorman AM. (2005) Hypoxia induces neurite outgrowth in PC12 cells that is mediated through adenosine A2A receptors. Neuroscience 131, 321-329 (For PDF click here)

Gorman AM, Szegezdi E, Quigney DJ, Samali A. (2005) Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells. Biochem Biophys Res Commun 327, 801-810.   (For PDF click here)

Quigney DJ, Gorman AM, Samali A. (2003) Heat shock protects PC12 cells against MPP toxicity. Brain Research 993, 133-139 (For PDF click here)

Wu J, Gorman A, Xinghua Z, Ceccatelli S, Chen E. (2002) Involvement of caspase-3 in photoreceptor cell apoptosis induced by in vivo blue light exposure. Investigative Ophthalmology and Visual Science 43, 3349-3354 (For PDF click here)

Daré E, Gorman AM, Ahlbom E, Götz M, Momoi T, Ceccatelli S. (2001) Apoptotic morphology does not always require caspase activity in rat cerebellar granule neurons. Neurotoxicity Research 3, 501-514

Gorman AM, Hirt UA, Orrenius S, Ceccatelli S. (2000) Dexamethasone pre-treatment interferes with apoptotic death in glioma cells. Neurosci. 96, 417-425

Gorman A, Bonfoco E, Zhivotovsky B, Orrenius S, Ceccatelli S. (1999) Cytochrome c release and caspase-3 activation during colchicine-induced apoptosis of cerebellar granule cells. Eur. J. Neurosci. 11:1067-1073

Gorman AM, Hirt UA, Orrenius S, Ceccatelli S. (1999) Application of a fluorometric assay to detect caspase activity in thymus tissue undergoing apoptosis in vivo. J. Immunol. Methods. 226:43-48.

Gorman A, Heavey B, Creagh EM, Cotter TG, Samali A. (1999) Antioxidant-mediated inhibition of the heat shock response leads to apoptosis. FEBS Lett. 445:98-102.

Gorman A, McGowan A, Cotter TG. (1997) Role of peroxide and superoxide anion during tumour cell apoptosis. FEBS Lett. 404:27-33

Gorman AM, Samali A, McGowan AJ, Cotter TG. (1997) The use of flow cytometry techniques in studying mechanisms of apoptosis in leukemic cells Cytometry 29, 97-105

McGowan A, Ruiz-Ruiz MC, Gorman A, Lopez-Rivas A, Cotter TG. (1996) The role of proteases, PARP and free radicals during apoptosis of several leukemic cell lines FEBS Lett. 392, 299-303

Meredith C, Scott M, Rumsby P, Frandsen A, Schousboe A, Gorman AM, Griffiths R (1996) Sustained c-fos expression is associated with excitotoxicity during the development of neuronal cells in vitro. Biochem. Soc. Trans. 24:6S,/p>

Gorman A, Grieve A, Griffiths R. (1995). Modulation by ionotropic excitatory amino acids and K of trans-ACPD stimulated phosphoinositide hydrolysis in mouse cerebellar granule cells. J. Neurochem. 65:2473-2483.

Gorman A, Scott MP, Rumbsby PC, Meredith C, Griffiths R. (1995) Excitatory amino acid-induced cytotoxicity in primary cultures of mouse cerebellar granule cells correlates with elevated, sustained c-fos protooncogene expression. Neurosci. Lett. 191:116-120.

Gorman A, Griffiths R. (1994). Sulphur-containing excitatory amino acid-stimulated inositol phosphate formation in primary cultures of cerebellar granule cells is mediated predominantly by N-methyl-D-aspartate receptors. Neuroscience 59:299-308.

Griffiths R, Dunlop J, Gorman A, Senior J, Grieve A. (1994). L-Trans-pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1,3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters. Biochem. Pharmacol. 47:267-272.

Zisterer DM, Gorman A, Williams DC, Murphy MP. (1992). The effects of the peripheral-type benzodiazepine acceptor ligands, Ro-5-4864 and PK-11195, on mitochondrial respiration. Methods and Findings in Experimental and Clinical Pharmacology. 14:85-90.

Regan CM, Gorman A, Larsson OM, Maguire C, Martin ML, Schousboe A, Williams DC. (1990). In vitro screening for anticonvulsant-induced teratogenesis in neural primary cultures and cell lines. Preliminary observations. Int. J. Devl. Neuroscience. 8:143-150

Gorman A, O'Beirne G, Regan C, Williams DC. (1989). Antiproliferative actions of benzodiazepines in cultured brain cells is not mediated through the peripheral-type benzodiazepine acceptor. J. Neurochem. 539-855

REVIEW ARTICLES

Gorman AM, Doyle KM (2009) Considerations and recent advances in neuroscience. Biochem Soc Trans 37, 299-302

Gorman AM (2008) Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling. J Cell Mol Med 12, 2263-2280

Szegezdi E, Logue SE, Gorman AM and Samali A (2006) Mediators of ER stress-induced apoptosis. EMBO Reports 7, 880-885 (For PDF click here)

Concannon CG, Gorman AM, Samali A. (2003) On the role of Hsp27 in regulating apoptosis. Apoptosis 8, 61-70 (For PDF click here)

Bree RT, Stenson C, Grealy M, Byrnes L, Gorman AM, Samali A. (2002) longevity: role of apoptosis and replicative senescence. BioGerontology 3, 195-206 (For PDF click here)

Gorman AM, Ceccatelli S, Orrenius S. (2000) Role of mitochondria in neuronal apoptosis Dev. Neurosci. 22, 348-358

Gorman AM, Zhivotovsky B. (1999) Challenging the dogmas... Cell Death Diff. 6, 207-211

Gorman A, Orrenius S, Ceccatelli S. (1998) Apoptosis in neuronal cells: Role of caspases. NeuroReport 9:R49-R55.

Samali A, Gorman A, Cotter TG. (1997) Role of Bcr-abl in resistance to apoptosis. Adv. Pharmacol. 41, 533-552

Gorman A, McGowan A, Cotter TG. (1996) Oxidative stress and apoptosis in neurodegeneration. J. Neurol. Sci. 139:(Suppl) 45-52.

Samali A, Gorman A, Cotter TG. (1996) Apoptosis: The story so far... Experientia 52, 933-941

Fernandes RS, Gorman AM, McGahon A, Lawlor M, McCann S, Cotter TG. (1996) The repression of apoptosis by activated abl oncogenes in chronic myelogenous leukaemia Leukaemia 10, (Suppl) S17-S21

BOOK CHAPTERS

Reed Herbert K, Samali A, Gorman AM. (2006) The role of heat shock proteins in neuronal differentiation and development. In Heat Shock Proteins in Neural Cells, Chapter 3 (Christiane Richter-Landsberg, ed.), Landes Bioscience, TX, USA. ISBN: 0-387-39952-6  (For PDF click here)

Fitzgerald, U, Gorman AM, Samali A. (2006) Heat shock proteins and the regulation of apoptosis. In Heat Shock Proteins in Neural Cells, Chapter 5 (Christiane Richter-Landsberg, ed.), Landes Bioscience, TX, USA. ISBN: 0-387-39952-6. (For PDF click here)

Gorman A, McCarthy J, Finucane D, Reville W, Cotter T. (1996) Morphological assessment of apoptosis In Techniques in Apoptosis: A User's Guide pp 1-26 (Cotter, T.G. and Martin, S.J. eds.), Portland Press.

OTHER

Gorman AM (2006) Helping keep our neurons alive with neurotrophins. The Irish Scientist 2006 Yearbook

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