Prof. Bob Lahue

Career history:
1979   B.A. (Chemistry), University of Virginia
1984   Ph.D. (Biochemistry), University of California, Berkeley
1984-89   Postdoctoral Research Fellow, Department of Biochemistry,Duke University Medical Center.   Laboratory of Dr. Paul Modrich
1989-1996   Assistant Professor, Department of Biochemistry and Molecular Biology, University of Massachusetts Medical Center
1997-2005   Associate Professor, Eppley Institute for Cancer Research, University of Nebraska Medical Center
2005-2007   Professor, Eppley Institute for Cancer Research, and Associate Director for Education and Training, UNMC Eppley Cancer Center, University of Nebraska Medical Center
2007-2011   SFI Professor of Molecular Genetics, Department of Biochemistry, NUI Galway
2011-present Professor of Molecular Genetics, School of Natural Sciences, NUI Galway


Research Interests
DNA mutagenesis and repair
Trinucleotide repeat instability
Yeast genetics

Key Recent Publications

Gellon, L., Razidlo, D. F., Gleeson, O., Verra, L., Schulz, D, Lahue, R. S., and Freudenreich, C.  H.   PLoS Genetics  7(2): e1001298. doi:10.1371/journal.pgen.1001298 (2011).  New functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion.

Debacker, K., Frizzell, A., Gleeson, O., Kirkham-McCarthy, L., Mertz, T., and Lahue, R.S.   PLoS Biology  10(2): e1001257. doi:10.1371/journal.pbio.1001257 (2012).  Histone deacetylase complexes promote trinucleotide repeat expansions. 

Gannon, A-M. M, Frizzell, A., Healy, E., and Lahue, R.S.   Nucleic Acids Research  40 10324-1033 (2012).  MutSbeta and histone deacetylase complexes promote expansions of trinucleotide repeats in.

Full Publication list
Lab members
Dr. Elaine Lahue 
Katherine Turner
Lucy Kirkham
Claire Concannon
Dr. Yanfang Ye

Contact details
Bob.Lahuenuigalway.ie
353 91 49 5756 voice
353 91 49 5504 fax
Room 143a, Lower Corrib Wing, Discipline of Biochemistry

Positions available
Please contact Prof. Lahue directly for information.

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