NUI Galway, Biochemistry, NFL people, Muriel

Career history:

Since 2010, Honorary Research Lecturer in Cellular Genetics, School of Natural Sciences, NUI Galway

Since 2008, SFI Research Fellow, Genome Stability Laboratory, directed by Noel Lowndes

2004-08: Senior Postdoctoral fellow. Genome Stability Laboratory, NCBES, Biochemistry department, NUI Galway, Ireland.

2000-04: Research scientist, Gurdon Institute, Cambridge University.

1999-2000: Post-doctoral scientist, Clare Hall laboratories, Cancer Research UK.

Education:

1998: PhD, Cellular and Molecular Genetics, University Paris-Sud XI. France.

2009: Habilitation à diriger les recherches, University Paris-Sud XI. France.

2012 : Postgraduate certificate in Teaching and Learning - NUI Galway.

Research Interest:

Cancer biology, genome stability, eukaryotic model systems, DNA damage checkpoints, roles of chromatin and histone modifications in the DNA damage response, Signal transduction, DNA damage activated kinases, DNA damage mediators, Post-translational modifications, biochemistry, yeast genetics in both S. cerevisiae and S. pombe, DT40 chicken model system.

Recent Publications

• K. Finn, N. Lowndes*, M. Grenon*. The budding yeast DNA damage checkpoint. Cellular and Molecular Life Sciences (2012) May;69(9):1447-73. Epub 2011 Nov 15

• J. FitzGerald, S. Moureau, P. Drogaris, E. O’Connell, N. Abshiru, A. Verreault, P. Thibault, M. Grenon* and N. F. Lowndes* Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor. PLoS One, , 6(2): e14714. doi:10.1371/journal.pone.0014714 (2011).

• Granata M, Lazzaro F, Novarina D, Panigada D, Puddu F, Abreu CM, Kumar R, Grenon M, Lowndes NF, Plevani P, Muzi-Falconi M. Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity. PLoS Genetics. Aug 5;6(8). (2010)

  Teaching Activities:

•  Since 2004, supervision of postgraduates and undergraduates research students

• Since 2010, C oordinator of 2^nd year biotechnology, directed by Andrew Flaus

• Since 2009, lecture to 1^st and 2^nd year biotechnology students

• Since 2010, Course development for 1^st and 2^ndyear Biotechnology students

Work presented on 9-10 June 2011 - NAIRTL 5th Annual Conference and Galway Symposium on Higher Education :

• M. Grenon, A. Flaus, A. Gorman. Engaging Science Students Through Research Seminar Presentations.

• Gorman, M. Grenon, J. Brown, H. Dodson and A. Flaus. Posters as a Student Engagement Approach in First Year Science.

Science education and outreach:

 • Cell Explorers: Outreach activity aimed at promoting cellular and molecular biology in primary school aged children and general public.

 o   Mai-June 2012: Cell Explorers works with 5^th class at Galway Educate Together National School  

Support from “ NUI Galway / NUI Galway Students’ Union EXPLORE Innovation Initiative”

o   November 2012: School visits during the Galway Science and Technology Festival

Supported by Royal Dublin Society demonstration lecture bursary

o   Cell Explorers Show on exhibition day – Book here

Supported by the Biochemical society , the “ NUI Galway / NUI Galway Students’ Union EXPLORE Innovation Initiative” 

•  EXPLORING ESOF : Undergraduate students often have limited opportunities to attend conferences relating to their area of study. This project offered the opportunity to an undergraduate student to  attend Europe’s largest general science conference, Euroscience Open Forom ESOF
Supported by “ NUI Galway / NUI Galway Students’ Union EXPLORE Innovation Initiative”

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