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Prof. BRIAN McSTAY

Career history:
1980             B.A. (Genetics), Trinity College Dublin
1984             Ph.D. (Zoology), University of Edinburgh
1984-92         Postdoctoral Research Fellow, Fred Hutchinson Cancer Research Centre, Seattle, USA. Laboratory of Dr Ronald H. Reeder
1992-2001     Lecturer, Biomedical Research Centre, University of Dundee, UK.
2001-2008     Senior Lecturer, Biomedical Research Centre, University of Dundee, UK.
2008-present SFI Professor of Genetics, Department of Biochemistry, NUI Galway

Research Interests
Gene Expression
Nuclear Structure
Ribosomal genes and the nucleolus.

Key Recent Publications
Mais, C., Wright, J.E., Prieto, J.L., Raggett, S.L. and McStay B. (2005) UBF Binding Site Arrays Form Pseudo-NORs and Sequester the RNA Pol I Transcription Machinery. Genes and Development 19, 50-64

McStay B. (2006) Nucleolar dominance: a model for rRNA gene silencing. Genes and Development. 20, 1207-1214

F. J. Lawrence, B. McStay and D. A. Matthews (2006) Nucleolar protein Upstream Binding Factor is sequestered into adenovirus DNA replication centres during infection without affecting RNA polymerase I location or ablating rRNA synthesis. J. Cell. Sci 119, 2621-2631

Prieto, J.L. and McStay B (2007) Factors linking transcription and processing of pre-rRNA in human cells are recruited to nucleolar organiser region chromatin independent of transcription. Genes and Development 21, 2041-2054

McStay, B and Grummt, I (2008) The epigenetics of rRNA genes: from molecular to chromosome biology. Annual Review of Cell and Developmental Biology 24 (in press)

Prieto, J.L. and McStay, B. (2008) Pseudo-NORs a novel model for studying nucleoli. BBA - Molecular Cell Research, Special Issue (in press)

Full Publication List

Lab members

Postdoctural Researchers
José-Luis Prieto
Alice Grob

PhD students
Christine Colleran
Marjolein Van Sluis
Ioanna Floutsakou

Contact details
Prof. Brian McStay
SFI Research Professor
Dept of Biochemistry
NUI Galway
Galway
Email: brian.mcstaynuigalway.ie
Tel: 353 91 49 2423
Fax: 353 91 49 5504

Positions available
Studentship and post-doctoral positions available. Contact Brian McStay directly for further information.

Biochemistry, School of Natural Science.
National University of Ireland, Galway, University Road, Galway, Ireland.
Phone: +353 (0)91 492420
E-mail: Biochemistry
This page was last updated Tuesday, January 18, 2011