Prof. Ciaran Morrison
Career history:
Professor at NUI Galway, 2011.
SFI Principal Investigator awards 2002, 2008, 2011.
Senior Lecturer, NUI Galway Biochemistry, July 2005.
Postdoctoral fellowship (EMBO), Edinburgh University 1999-2002.
Postdoctoral fellowship (JSPS), Kyoto University 1997-1999.
PhD (Dr. rer. nat.) 1997, University of Vienna (IMP).
MSc 1993, NUI Galway.
BSc (Hons) 1991, NUI Galway.
Research interests:
- DNA damage responses and the centrosome.
- How centrosomes duplicate during the cell cycle.
- Roles of the Smc5/6 complex in chromosome maintenance.
- Activities of Mcph1 microcephalin in DNA damage responses.
Key recent publications
Dantas, T.J., Wang, Y., Lalor, P., Dockery, P. and
Morrison, C.G.
(2011) Defective nucleotide excision repair with normal centrosome structures and functions in the absence of all vertebrate centrins.
J. Cell Biol., 193: 307-318.
Stephan, A., Kliszczak, M., Cooley, C., Dodson, H. and
Morrison, C.G. (2011) Roles of vertebrate Smc5 in sister
chromatid cohesion and homologous recombinational repair.
Mol. Cell. Biol., 31: 1369-1381.
Inanc, B., Dodson, H. and
Morrison, C.G. (2010) A centrosome-autonomous signal that involves
centriole disengagement permits centrosome duplication in G2 phase after DNA damage.
Mol. Biol. Cell, 21: 3866-3877.
Brown, J.A., Bourke, E., Liptrot, C., Dockery, P. and
Morrison, C.G. (2010) MCPH1/ BRIT1 limits ionizing radiation-induced centrosome amplification.
Oncogene, 29: 5537-5544.
Bourke, E., Brown, J.A., Takeda, S., Hochegger, H. and
Morrison, C.G. (2010) DNA damage induces Chk1-dependent threonine-160 phosphorylation and activation of Cdk2.
Oncogene 29: 616-24.
Dodson, H and
Morrison, C.G. (2009) Increased sister chromatid cohesion and DNA damage response factor localization at an enzyme-induced DNA double-strand break in vertebrate cells.
Nucleic Acids Res. 37: 6054-6063.
Full publication list
Current Lab members
Postdoctoral fellows:
Anna Stephan (M.Sc., Ph.D., Biochemistry, NUI Galway)
David Gaboriau (M.Sc., Ph.D., Biochemistry, Cambridge University)
Alicja Antonczak (M.Sc., Ph.D., Cardiff University)
Sandra Cuffe (B.Sc., Ph.D. University College Dublin)
Graduate students:
Tiago Dantas (B.Sc., Applied Biology, University of Minho).
Pauline Conroy (B.Sc., Biotechnology, NUI Galway).
Yi-fan Wang (B.Sc., China Pharmaceutical U.; M.Sc., Shanghai Inst. Biochem, CAS).
Loretta Breslin (B.Sc., De Montfort University; M.Sc. NUI Galway).
Owen Daly (B.Sc., Trinity College Dublin).
Anne-Marie Flanagan (B.Sc., NUI Galway).
Research Assistant:
Sinead King (B.Sc., M.Sc., UCC)
Previous lab members
Dr. Thomas Wenner (2003-2005) now at Université de Lyon, France.
Dr. Virginie Faure (2005-2007) now at CNRS UPR3081, Marseilles, France.
Dr. Liam Jeffers (2003-2007) now 'in industry' in Ireland.
Mr. Seamus Stack (2005-2007) now a PhD student in Glasgow, UK.
Dr. Barry Coull (2006-2008) now at the University of Maastricht.
Dr. Carol Cooley (2004-2009) now at the GDSC, University of Sussex, UK.
Dr. James Brown (2007-2009) now at NUI Galway.
Dr. Helen Dodson (2003-2010) now a lecturer in Anatomy at NUI Galway.
Dr. Emer Bourke (2003-2010) now a lecturer in Pathology, NUI Galway.
Dr. Chiara Saladino (2006-2010) now at NUI Galway.
Dr. Maciej Kliszczak (2007-2011) now at the Faculty of Health Sciences, University of Copenhagen.
Dr. Burcu Inanç (2008-2011) now at the Netherlands Cancer Institute, Amsterdam.
Lectures/ courses
4th year Biochemistry course on ’Chromosome organisation and dynamics’.
4th year Biochemistry course on 'Research paper analysis' .
4th year Biochemistry course on 'Experimental design and planning'.
2nd year Biochemistry course on 'Cell signalling'.