Professor Afshin Samali

• Career history:
  2008-present Head of Biochemistry, NUI Galway
  2007-present Personal Professor, Department of Biochemistry, NUI, Galway
  2004-2007 Senior Lecturer, Department of Biochemistry, NUI, Galway
  2001-present Research Director, NCBES, NUI, Galway
  2000-2004 Lecturer, Department of Biochemistry, NUI, Galway
  1998-1999 Research Fellow, Division of Toxicology, Karolinska Institute, Stockholm
  1997-1998 Marie Curie Fellow, Division of Toxicology, Karolinska Institute, Stockholm
  1993-1997 University College Cork (UCC), Ireland, Ph.D. (Biochemistry)
  1989-1993 B.Sc. Biology, National University of Ireland, Maynooth, Ireland 
  
  
• Research Interests: NUI, Galway, Department of Biochemistry, AS Lab
  The main research objective is to delineate the signalling pathways during cellular stress and apoptosis. In particular, we focus on:
  Communication between cellular organelles
  Mechanism of apoptosis induced by stress to the endoplasmic reticulum
  Mechanisms of inhibition of apoptosis by heat shock proteins
  Development of novel cancer therapeutics based on TRAIL
  


• Key publications:
  1. Szegezdi E., Logue S.E., Gorman A.M., Samali A. (2006) Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 7: 880-5
  
  2. van der Sloot A.M., Tur V., Szegezdi E., Mullally M.M., Cool R.H., Samali A., Serrano L., Quax W.J. (2006) Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor. PNAS vol. 103, 23:8634-8639
  
  3. Samali A., Cai J., Zhivotovsky B., Jones D.P., Orrenius S. (1999) Presence of pre-apoptotic complex of pro-caspase-3 with Hsp60 and Hsp10 in mitochondrial fraction of Jurkat cells. EMBO J. 18: 2040-2048. 
  
  
• Lectures/Courses
  Third year Biochemistry:
  Lectures in Cellular Stress & Apoptosis (Biochemistry) 2001-present
  Lectures in Membranes & Signalling (Medicine) 2001-present
  Fourth Year Biochemistry:
  Lectures in Apoptosis (Biochemistry, Biotechnology, Biomedical Science) 2000-present
  

• NUI, Galway, Department of Biochemistry, AS Lab  
  
  

• Senior Research Fellows
  Sanjeev Gupta (B.Sc. Delhi University, Delhi, India, M.Sc. Biochemistry Hamdard University, New Delhi, India,
  Ph.D. Jawaharlal Nehru University, New Delhi, India)
  Email: sanjeev.guptanuigalway.ie

Sandra Healy (B.Sc. Biochemistry, Ph.D. Biochemistry, University College Cork)
Email: sandra.healynuigalway.ie

Eva Szegezdi  (M.Sc. Molecular Biology & Biochemistry, Ph.D. Medical Sciences, University of Debrecen, Hungary)
Email: eva.szegezdinuigalway.ie

• Postdoctoral Researcher
  Parisa Mousavi-Shafaei (M.Sc. Biochemistry, Ph.D. Biochemistry, University of Tehran, Iran)
  Email: parisa.mousavishafaeinuigalway.ie
  
  
• Research Assistants
  Aoife O'Reilly (B.Sc. HDIP (App Micro))
  Email: aoife.oreillynuigalway.ie
  
  Maria Ryan (B.Sc. Microbiology, M.Sc. Biotechnology, NUI Galway)
  Email:  maria.ryannuigalway.ie 
  
  
• Postgraduate Students

  Colin Brooks (B.Sc. Biochemistry, NUI Galway)
  Email: colin.brooksnuigalway.ie 

  Karen Cawley (B.Sc. Biochemistry, NUI Galway)
  Email: k.cawley1nuigalway.ie
  
  Shane Deegan (B.Sc. Biochemistry, NUI Galway)
  Email: s.deegan1gmail.com
  
  Ayswaria Deepti (M.Sc. Biotechnology, Bangalore University)
  Email: a.deepti1nuigalway.ie
  
  Sarah Dolan (B.Sc. Biochemistry, NUI Galway.)
  Email: sarah.dolannuigalway.ie
  
  Ruth Morrell (MB BCh, NUI Galway, MRCP Ireland, FRCPath UK)
  Email: ruthmorrellyahoo.co.uk
  
  Marianne Van Dijk (M.Sc. Molecular Biology and Biotechnology, University of Groningen, The Netherlands)
  Email: m.vandijk1nuigalway.ie

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