Aldabbagh-Research Group

Head of Group - Fawaz Aldabbagh B. Sc. (HONS), Ph. D., CChem, MRSC

Fawaz (b. 9.11.71, 35 years old) joined NUI, Galway as Lecturer in April 2000. His group has a wide range of research interests including materials/polymer, organic/medicinal and environmental/green chemistry. Fawaz is currently the author of 33 peer-reviewed papers, review articles and book chapters in top international chemistry journals; 24 published since 2003, as principle (corresponding) author (200+ citations). Invited research lectures have been given across the world, including in Australia, the Netherlands, Ireland, Italy, Japan, UK and USA. There are currently seven postgraduates in his group, seven others have gained PhDs. Fawaz also teaches chemistry at all levels in the department, and is very active in science promotions at a faculty and national level.

 

PhD Students

Sarah Hehir B. Sc. (HONS) - Synthesis and biological activity of new bioreductive anticancer agents. Sarah has been carrying out biological assays in collaboration with Dr. Michael P. Carty (Biochemistry, NUI, Galway). Sarah has been awarded an IRC EMBARK Initiative Postgraduate Scholarship to carry out this project.

Ronan  McHale B. Sc. (HONS) - Stimuli-responsive grafted materials (smart polymers) prepared via the macromonomer approach in collaboration with Prof. Yamada (Osaka City University, Japan) and Dr. W. M. Carroll (NUI, Galway). Nitroxide-mediated controlled/living radical polymerizations in supercritical carbon dioxide are being carried out in collaboration with Prof. Okubo (Kobe University, Japan) and Prof. Zetterlund (Kobe University, Japan). Ronan has been awarded an IRC EMBARK Initiative Postgraduate Scholarship to carry out this project.

Orla Gibbons B. Sc. (HONS) - Joint Supervision with Dr. W. M. Carroll (NCBES and NUI, Galway) - Thermoresponsive acrylamides prepared by controlled/living radical polymerizations for use in drug-delivery systems. This project is in collaboration with Prof. Yamada. Orla has been awarded an IRC EMBARK Initiative Postgraduate Scholarship to carry out this project.

Liz O'Donovan B. Sc (HONS) - Synthesis and antitumor activity of novel benzimidazolequinones.  Biological assays are being carried out in collaboration with Dr. Michael P. Carty (Biochemistry, NUI, Galway). Liz joined the group from University College Cork, and has been awarded an IRC EMBARK Initiative Postgraduate Scholarship to carry out this project. Liz is a recipient of an Oncology Scholar Travel Award from Cancer Research Ireland.

Karen Fahey B. Sc (HONS) - Synthesis and antitumor activity of novel benzimidazolequinones.  Biological assays are being carried out in collaboration with Dr. Michael P. Carty (Biochemistry, NUI, Galway). Karen joined the group after working in industry, and has been awarded an IRC EMBARK Initiative Postgraduate Scholarship to carry out this project.

Eoin Moriarity B. Sc (HONS) - Eoin is working on Environmental Protection Agency (EPA) funded project entitled "Photochemical Alternatives to Hazardous Radical Initiators for the Synthesis of Potent Anti-Tumour Agents."

Aideen Beatty B. Sc (HONS) - Aideen joined the group in January 2007, is working in the area of controlled polymer synthesis and click chemistry.

 

Group Graduates with PhD Thesis Titles

Dr. Paul Dervan (2004) - "2,5- and 2,6-Spirodicyclohexyl Substituted Cyclic Nitroxide-Mediated Free Radical Polymerizations of Styrene."

Dr. John O'Shaughnessy (2005) - "Synthesis of Bioreductive Antibiotics: Pyrrolo- and Pyrido-[1,2-a]benzimidazolequinones Containing a Fused Cyclopropane Ring using Intramolecular Cycloaddition Reactions."

Dr. Padraig McLoughlin (2005) - "Homolytic Aromatic Substitution Reactions of s-Imidazole Radicals"

Dr. Mairéad A. Clyne (2006) - "Photochemical and n-Tributyltin Hydride-mediated Aromatic Substitutions of s-Imidazole Radicals"

Dr. Marisa Phelan (2006) - "Mechanism and Kinetics of the Free Radical Ring-Opening Polymerization of Cyclic Allylic Sulfide Monomers"

Dr. Julia Ryan (2006) - "First Nitroxide-mediated Controlled/Living Radical Polymerizations (NMP) in Ionic Liquid, Dispersions in Supercritical Carbon Dioxide and Copolymerizations with Macromonomers"

Dr. Mary Lynch (2007) - "Synthesis of [1,2-a] Alicyclic Ring-Fused Benzimidazolequinone Bioreductive Anti-Tumour Agents by Novel Radical Cyclizations"

 

Visitors

Hervé Clavier (E.N.S.C.R., France) - 2001, Marianne Ellerbek Sørensen (Aalborg, Denmark) - 2003

Sarah Reilly B. Sc. (HONS) and Derrick Reape B. Sc. (HONS)- 2005, MSc. in Analytical Biochemistry and Chemistry

Professor Bunichiro Yamada - Walton Visitor - Professor Yamada of Osaka City University, a recognized world leader in polymeric materials synthesis worked in our group from June 2004 until September 2005.

 

Research Awards & Grants

Science Foundation Ireland (SFI) Research Frontiers Programme 2007

Environmental Protection Agency (EPA) 2006

Science Foundation Ireland (SFI) E.T.S. Walton Visitor Award 2004 (in collaboration with Dr. W. M. Carroll, Department of Chemistry & NCBES, NUI, Galway)

Enterprise Ireland International Collaboration Awards 2001, 2002 and 2003

Enterprise Ireland Basic Research Grant 2002

National University of Ireland, Galway Millennium Research Awards 2001, 2002, 2003 (travel) and 2005 (travel)

IRCSET EMBARK Initiative Postgraduate Scholarships 2002, 2004, 2005, 2006, 2007

 

Collaborators  

Professor Masayoshi Okubo and Associate Professor Per B. Zetterlund (Kobe University)

Dr. Michael P. Carty (Biochemistry, NUI, Galway)

 

Key words- Bioreductive Antitumour Agents, Free Radicals, Green Chemistry, Heterocycles, Nitroxides, Organic Synthesis, Polymer Kinetics, Polymer Synthesis, Sulfur Chemistry

Back to Home Page