Aldabbagh - Refereed PUBLICATIONS

2011

53. "First Synthesis of An Aziridinyl Fused Pyrrolo[1,2-a]benzimidazole and Toxicity Evaluation Towards Normal and Breast Cancer Cell Lines," Sarah Bonham, Liz O'Donovan, Michael P. Carty and Fawaz Aldabbagh, Organic and Biomolecular Chemistry 2011, Accepted Manuscript. http://pubs.rsc.org/en/content/articlelanding/2011/ob/c1ob05694h

52. "Acetic Anhydride Generated Imidazolium Ylide in Ring Closures onto Carboxylic Acids; Part of the Synthesis of New Potential Bioreductive Antitumor Agents," Eamonn Joyce, Patrick McArdle, Fawaz Aldabbagh, Synlett 2011, 1097-1100. https://www.thieme-connect.com/ejournals/abstract/synlett/doi/10.1055/s-0030-1260543

51. "Chain Transfer to Solvent in the Radical Polymerization of N-Isopropylacrylamide," Yusuke Sugihara, Padraig O'Connor, Per B. Zetterlund, Fawaz Aldabbagh, Journal of Polymer Science: Part A: Polymer Chemistry 2011, 49, 1856-1864. http://onlinelibrary.wiley.com/doi/10.1002/pola.24612/abstract;jsessionid=D6DD068A1D70995A59AB47A17A7B51F2.d01t01

50. "Nitroxide-Mediated Stabilizer-Free Inverse Suspension Polymerization of N-Isopropylacrylamide in Supercritical Carbon Dioxide," Padraig O'Connor, Per B. Zetterlund, Fawaz Aldabbagh, Journal of Polymer Science: Part A: Polymer Chemistry 2011, 49, 1719-1723. http://onlinelibrary.wiley.com/doi/10.1002/pola.24580/abstract


2010

49. "Synthesis and Toxicity Towards Normal and Cancer Cell Lines of Benzimidazolequinones Containing Fused Aromatic Rings and 2-Aromatic Ring Substituents," Eoin Moriarty, Miriam Carr, Michael P. Carty, Fawaz Aldabbagh, European Journal of Medicinal Chemistry 2010, 45, 3762-3769. doi:10.1016/j.ejmech.2010.05.025 

48. RSC Prospect:  "One-Pot Double Intramolecular Homolytic Aromatic Substitution Routes to Dialicyclic Ring Fused Imidazobenzimidazolequinones and Preliminary Analysis of Anti-Cancer Activity," Vincent Fagan, Sarah Bonham, Michael P. Carty and Fawaz Aldabbagh, Organic and Biomolecular Chemistry 2010, 8, 3149-3156. http://www.rsc.org/Publishing/Journals/OB/article.asp?doi=c003511d

47. "The Influence of the Aziridinyl Substituent of Benzimidazoles and Benzimidazolequinones on Toxicity Towards Normal and Fanconi Anaemia Cells," Karen Fahey, Liz O'Donovan, Miriam Carr, Michael P. Carty, Fawaz Aldabbagh, European Journal of Medicinal Chemistry 2010, 45, 1873-1879. doi:10.1016/j.ejmech.2010.01.026 

46. "Effect of Monomer Loading and Pressure on Particle Formation in Nitroxide-Mediated Precipitation Polymerization in Supercritical Carbon Dioxide," Padraig O'Connor, Per B. Zetterlund and Fawaz Aldabbagh, Macromolecules 2010, 43, 914-919.  http://dx.doi.org/10.1021/ma90221


2009

Invited Article: "Highly Potent Bioreductive Benzimidazolequinone Anti-Tumour Agents," Karen Fahey and Fawaz Aldabbagh, Irish Chemical News 2009, 25 (2) 24-27.

45. "Synthesis of Aryl Ring-Fused Benzimidazolequinones using 6-exo-trig Radical Cyclizations," Eoin Moriarty and Fawaz Aldabbagh, Tetrahedron Letters 2009, 50, 5251-5253. doi:10.1016/j.tetlet.2009.07.023  

44. Highlight: "Controlled/Living Heterogeneous Radical Polymerization in Supercritical Carbon Dioxide," Per B. Zetterlund, Fawaz Aldabbagh, Masayoshi Okubo, Journal of Polymer Science: Part A: Polymer Chemistry 2009, 47, 3711-3728. http://www3.interscience.wiley.com/journal/122454906/abstract

43. Book Chapter: F. Aldabbagh and O. Gibbons, in Science of Synthesis 2010, Houben-Weyl Methods of Molecular Transformations, vol. 45b, Product Class 18: Polystyrenes, chapter 45.18, pp 723-744. (ISBN 978-3-13-146551-1).


2008

42. RSC Prospect: "First Synthesis of N-[(Aziridinyl-2-yl)methyl]Benzimidazolequinone and Analysis of Toxicity Towards Normal and Fanconi Anemia Cells," Liz O'Donovan, Michael P. Carty and Fawaz Aldabbagh, Chemical Communications 2008, 5592-5594. DOI: 10.1039/b814706j

41. "Nitroxide-Mediated Precipitation Polymerization of Styrene in Supercritical Carbon Dioxide: Effect of Monomer Loading and Nitroxide Partitioning on Control," Fawaz Aldabbagh, Per B. Zetterlund, Masayoshi Okubo, European Polymer Journal, 2008, 44, 4037-4046. doi:10.1016/j.eurpolymj.2008.09.020 

40. "Nitroxide-Mediated Radical Polymerization of N-tert-Butylacrylamide,” Orla Gibbons, William M. Carroll, Fawaz Aldabbagh, Per B. Zetterlund, Bunichiro Yamada, Macromolecular Chemistry and Physics 2008, 209, 2434-2444. 10.1002/macp.200800358

39. "Synthesis of Seven and Eight-Membered [1,2-a] Alicyclic Ring-Fused Benzimidazoles and 3-Azirdinylazepino[1,2-a]benzimidazolequinone as a Potential Antitumor Agent," Karen Fahey and Fawaz Aldabbagh, Tetrahedron Letters 2008, 49, 5235-5237. doi:10.1016/j.tetlet.2008.06.121 

38. "Synthesis of Dimethyl Substituted Benzimidazoles Containing Cyclopropane Fused onto Five to Eight Membered [1,2-a]Alicyclic Rings and Influence of Methyl Group Substituents on Cytotoxicity of Benzimidazolequinones," Sarah Hehir, Liz O'Donovan, Michael P. Carty, Fawaz Aldabbagh, Tetrahedron 2008, 64, 4196-4203. doi:10.1016/j.tet.2008.02.093  

37. "Improved Control in Nitroxide-Mediated Radical Polymerization Using Supercritical Carbon Dioxide,” Fawaz Aldabbagh, Per B. Zetterlund, Masayoshi Okubo, Macromolecules 2008, 41, 2732-2734. DOI: 10.1021/ma702645b
 

36. Invited Review: Fawaz Aldabbagh, in Comprehensive Heterocyclic Chemistry III, Alan R. Katritzky Exec Ed; Christopher A Ramsden, Eric F. V. Scriven, and Richard J. K. Taylor Ed; Elsevier; Ray C. F. Jones, Vol. Ed; Volume 10, Chapter 10.13, Bicyclic 5-6 Systems: Five Heteroatoms 2:3 or 3:2, pp 661-702. (ISBN 978-0-08-045002-5)  .

35. "Nitroxide-Mediated Controlled/Living Radical Copolymerizations with Macromonomers," Julia Ryan, Fawaz Aldabbagh, Per B. Zetterlund, Bunichiro Yamada, Reactive and Functional Polymers 2008, 68, 692-700. doi:10.1016/j.reactfunctpolym.2007.11.007


2007

34. "Polymerization of N-Isopropylacrylamide in the Presence of Poly(acrylic acid) and Poly(methacrylic acid) Containing Unsaturated End-Groups," Ronan McHale, Fawaz Aldabbagh, William M. Carroll, Bunichiro Yamada, Journal of Polymer Science: Part A: Polymer Chemistry 2007, 45, 4394-4400. http://www3.interscience.wiley.com/cgi-bin/abstract/114801184/ABSTRACT

33. "Nitroxide-Mediated Radical Precipitation Polymerization of Styrene in Supercritical Carbon Dioxide," Ronan McHale, Fawaz Aldabbagh, Per B. Zetterlund,  Masayoshi Okubo, Macromolecular Chemistry and Physics 2007, 208, 1813-1822. http://www3.interscience.wiley.com/cgi-bin/abstract/114300217/ABSTRACT

32. "The Role of Excess Nitroxide in the SG1 (N-tert-butyl-N-[1-diethylphosphono-(2,2-dimethylpropyl)]nitroxide)-Mediated Polymerization of Methyl Methacrylate," Ronan McHale, Fawaz Aldabbagh, Per B. Zetterlund, Journal of Polymer Science: Part A: Polymer Chemistry 2007, 45, 2194-2203. http://www3.interscience.wiley.com/cgi-bin/abstract/114210429/ABSTRACT

31. "Synthesis by Radical Cyclization and Cytotoxicity of Highly Potent Bioreductive Alicyclic Ring Fused [1,2-a] Benzimidazolequinones, " Mary Lynch, Sarah Hehir, Paul Kavanagh, Donál Leech, John O'Shaughnessy, Michael P. Carty, Fawaz Aldabbagh, Chemistry - A European Journal 2007, 13, 3218-3226. http://dx.doi.org/10.1002/chem.200601450


2006

30. "Nitroxide-mediated Radical Polymerization of Styrene: Experimental Evidence of Chain Transfer to Monomer," Per B. Zetterlund, Yuichi Saka, Ronan McHale, Tadashi Nakamura, Fawaz Aldabbagh, Masayoshi Okubo, Polymer 2006, 47, 7900-7908. doi:10.1016/j.polymer.2006.09.033 

29. "Nitroxide-mediated Controlled Statistical Copolymerization of N-Isopropylacrylamide with N-tert-Butylacrylamide," Orla Gibbons, William M. Carroll, Fawaz Aldabbagh, Bunichiro Yamada, Journal of Polymer Science: Part A: Polymer Chemistry 2006, 44, 6410-6418. http://www3.interscience.wiley.com/cgi-bin/abstract/113379045/ABSTRACT

28. "Nitroxide-Mediated Radical Dispersion Polymerization of Styrene in Supercritical Carbon Dioxide using a Poly(dimethylsiloxane-b-methyl methacrylate) Stabilizer,"  Ronan McHale, Fawaz Aldabbagh, Per B. Zetterlund, Hideto Minami, Masayoshi Okubo, Macromolecules 2006, 39, 6853-6860. http://pubs.acs.org/cgi-bin/abstract.cgi/mamobx/2006/39/i20/abs/ma061154n.html

27. "Nitroxide-Mediated Radical Dispersion Polymerization of Styrene in Supercritical Carbon Dioxide using Poly(dimethylsiloxane-b-styrene) Alkoxyamine as Initiator and Stabilizer," Ronan McHale, Fawaz Aldabbagh, Per B. Zetterlund,  Masayoshi Okubo, Macromolecular Rapid Communications 2006, 27, 1465-1471. http://www3.interscience.wiley.com/cgi-bin/abstract/112772242/ABSTRACT

26. "Intramolecular Aromatic Substitutions of the Imidazol-5-yl Radical to form Tricyclic Imidazo[5,1-a] Heterocycles," Fawaz Aldabbagh and Mairéad A. Clyne, Letters in Organic Chemistry 2006, 3, 510-513.

25. "Copolymerization of Eight-Membered Ring-Opening Allylic Sulfide Lactone and Disulfide Monomers with Methyl Methacrylate and Styrene," Marisa Phelan, Fawaz Aldabbagh, Per B. Zetterlund, Bunichiro Yamada, European Polymer Journal 2006, 42, 2475-2485. DOI: j.eurpolymj.2006.04.011

24. Invited Book Chapter: Fawaz Aldabbagh, W. Russell Bowman, John D. Storey, in Investigation of Organic Reaction Mechanisms, Howard Maskill, Ed; Blackwell Publishing, 2006, chapter10, Investigation of Reactions Involving Radical Intermediates, pp 261-292. ISBN.140513142X

23. "Photochemical Intramolecular Aromatic Substitutions of the Imidazol-2-yl Radical are Superior to those Mediated by Bu3SnH," Mairéad A. Clyne and Fawaz Aldabbagh, Organic & Biomolecular Chemistry 2006, 4, 268-277. DOI: 10.1039/b512729g


2005

Green living polymers,” Fawaz Aldabbagh, p. 79 , The Irish Scientist, 2005 Year Book, No. 13, November 2005.

22. "Mechanism and Kinetics of the Free Radical Ring-Opening Polymerization of Cyclic Allylic Sulfide Lactones," Marisa Phelan, Fawaz Aldabbagh, Per B. Zetterlund, Bunichiro Yamada, Polymer 2005, 46, 12046-12056. doi:10.1016/j.polymer.2005.11.006 

21. "Efficient Synthesis and Copolymerization of Polyacrylic Acid and Polyacrylic Ester Macromonomers: Manipulation of Steric Factors", Ronan McHale, Fawaz Aldabbagh, William M. Carroll, Bunichiro Yamada, Macromolecular Chemistry and Physics 2005, 206, 2054-2066. http://www3.interscience.wiley.com/cgi-bin/fulltext/112125505/PDFSTART

20. "First Nitroxide-mediated Free Radical Dispersion Polymerizations of Styrene in Supercritical Carbon Dioxide," Julia Ryan, Fawaz Aldabbagh, Per B. Zetterlund, Masayoshi Okubo, Polymer 2005, 46, 9769-9777.  doi:10.1016/j.polymer.2005.08.039  

19. "Mechanism and Kinetics of the Free Radical Ring-Opening Polymerization of Eight-Membered Cyclic Allylic Disulfide Monomers," Marisa Phelan, Fawaz Aldabbagh, Per B. Zetterlund, Bunichiro Yamada," Macromolecules 2005, 38, 2143-2147. http://pubs.acs.org/cgi-bin/abstract.cgi/mamobx/2005/38/i06/abs/ma047894i.html

18. "Synthesis of Pyrrolo- and Pyrido-[1,2-a]benzimidazolequinone Antitumor Agents Containing a Fused Cyclopropane Ring," John O'Shaughnessy and Fawaz Aldabbagh, Synthesis 2005, 1069-1076. http://www.thieme-connect.com/ejournals/abstract/synthesis/doi/10.1055/s-2005-861832

17. "Addition-Fragmentation Chain Transfer to Polymer in the Free Radical Ring-Opening Polymerization of an Eight-membered Cyclic Allylic Sulfide Monomer" Marisa Phelan, Fawaz Aldabbagh, Per B. Zetterlund, Bunichiro Yamada, Macromolecular Theory and Simulations 2005, 14, 109-116. http://www3.interscience.wiley.com/cgi-bin/abstract/109924779/ABSTRACT

16. Invited Review: Fawaz Aldabbagh, in Comprehensive Organic Functional Group Transformations II, Alan R. Katritzky and Richard J. K. Taylor, Ed; Elsevier; Ray C. F. Jones, Vol. Ed; 2005, volume 5, chapter 5.01, Acid Halides, pp 1-17. (ISBN 0-08-044256-0)

15. Invited Review: Fawaz Aldabbagh, in Comprehensive Organic Functional Group Transformations II, Alan R. Katritzky and Richard J. K. Taylor, Ed; Elsevier; Keith Jones, Vol. Ed; 2005, volume 3, chapter 3.06, Ketones Bearing an a, b-Aryl or - Hetaryl Substituent, pp 267-308. (ISBN 0-08-044256-0)

14. Invited Review: Fawaz Aldabbagh, in Comprehensive Organic Functional Group Transformations II, Alan R. Katritzky and Richard J. K. Taylor, Ed; Elsevier; Keith Jones, Vol. Ed; 2005, volume 3, chapter 3.03, Aldehydes: Aryl and Heteroaryl Aldehydes, pp 99-133. (ISBN 0-08-044256-0)


2004

13. "Synthesis of Benzimidazolequinone Analogue of Cyclopropamitosene Antitumor Agents," John O'Shaughnessy, Desmond Cunningham, Paul Kavanagh, Dónal Leech, Patrick McArdle, Fawaz Aldabbagh, Synlett 2004, 2382-2384. http://www.thieme-connect.com/ejournals/abstract/synlett/doi/10.1055/s-2004-831341

12.    "Intermolecular "Oxidative" Aromatic Substitution Reactions of the Imidazol-5-yl Radical mediated by the "Reductant" Bu3SnH," Padraig T. F. McLoughlin, Mairéad A. Clyne and Fawaz Aldabbagh, Tetrahedron 2004, 60, 8065-8071. doi:10.1016/j.tet.2004.06.120 

11.    "First Nitroxide-mediated Controlled/Living Free Radical Polymerization in an Ionic Liquid," Julia Ryan, Fawaz Aldabbagh, Per B. Zetterlund, Bunichiro Yamada, Macromolecular Rapid Communications 2004, 25, 930-934. http://www3.interscience.wiley.com/cgi-bin/abstract/108070231/ABSTRACT


2003

10.    "Influence of Nitroxide Structure on the 2,5- and 2,6-Spirodicyclohexyl Substituted Cyclic Nitroxide-mediated Free Radical Polymerization of Styrene," Fawaz Aldabbagh, Paul Dervan, Marisa Phelan, Karen Gilligan, Desmond Cunningham, Patrick McArdle, Per B. Zetterlund, Bunichiro Yamada, Journal of Polymer Science: Part A: Polymer Chemistry 2003, 41, 3892-3900. http://www3.interscience.wiley.com/cgi-bin/abstract/106561733/ABSTRACT

9.    "Mechanism and Kinetics of the Imidazolidinone-Nitroxide Mediated Free Radical Polymerization of Styrene," Paul Dervan, Fawaz Aldabbagh, Per B. Zetterlund, Bunichiro Yamada, Journal of Polymer Science: Part A: Polymer Chemistry 2003, 41, 327-334. http://www3.interscience.wiley.com/cgi-bin/abstract/101523781/ABSTRACT


1998-2000 (Postdoctoral Fellow, Griffith University, Australia 1998-2000)

8.    "The Reactivity of Sulfur-Centred Radicals towards TMIO (1,1,3,3-Tetramethyl-2,3-dihydroisoindol-2-yl-oxyl). A New Type of Radical Fragmentation Reaction,"  Fawaz Aldabbagh, W. Ken Busfield and Ian D. Jenkins, Australian Journal of Chemistry 2001, 54, 313-318. http://www.publish.csiro.au/nid/51/paper/CH01100.htm

7.    "Alkoxyamine-Mediated "Living" Radical Polymerization: MS Investigation of the Early Stages of Styrene Polymerization Initiated by Cumyl-TEISO," Salvacion Cresidio, Fawaz Aldabbagh, W. Ken Busfield, Ian D. Jenkins, San H. Thang, Clovia Zayas-Holdsworth and Per B. Zetterlund, Journal of Polymer Science: Part A: Polymer Chemistry 2001, 39, 1232-1241. http://www3.interscience.wiley.com/cgi-bin/abstract/77005590/ABSTRACT

6.    "The Reactivity of Nitroxides towards Alkenes," Fawaz Aldabbagh, W. Ken Busfield, Ian D. Jenkins and San H. Thang, Tetrahedron Letters 2000, 41, 3673-3676. doi:10.1016/S0040-4039(00)00440-8  


1997-1999 (PhD, Loughbourgh University, UK 1994-1997)

5.    "Oxidative Radical Cyclisations onto Imidazoles and Pyrroles using Bu3SnH," Fawaz Aldabbagh, W. Russell Bowman, Emma Mann and Alexandra M. Z. Slawin, Tetrahedron 1999, 55, 8111-8128. doi:10.1016/S0040-4020(99)00419-6 

4.     "Radical Cyclisations onto Imidazoles and Benzimidazoles," Fawaz Aldabbagh and W. Russell Bowman, Tetrahedron 1999, 55, 4109-4122. doi:10.1016/S0040-4020(99)00104-0

3.     "Oxidative Radical Cyclisations onto Imidazoles and Pyrroles using Bu3SnH," Fawaz Aldabbagh, W. Russell Bowman and Emma Mann, Tetrahedron Letters 1997, 38, 7937-7940. doi:10.1016/S0040-4039(97)10052-1 

2.    "Radical Cyclisations onto Imidazoles and Benzimidazoles," Fawaz Aldabbagh and W. Russell Bowman, Tetrahedron Letters 1997, 38, 3793-3794. doi:10.1016/S0040-4039(97)00740-5

 1.   Review: "The Synthesis of Heterocycles by Radical Cyclisations," Fawaz Aldabbagh and W. Russell Bowman, Contemporary Organic Synthesis 1997, 6, 261-280.

 

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