University of Galway

Course Module Information

Course Modules

Semester 1 and Semester 2 | Credits: 5

The module aims to give students a comprehensive understanding of fundamental as well as sophisticated research technologies relevant to molecular biology. The research technologies described during the module include the research approaches to study gene expression (including introduction to omics technologies) and genetic alterations (SNP, FISH, deep sequencing) followed by description of the state of the art approaches to carry out mechanistic studies, such as gene silencing (knockout, knock-in, knock down), CRISPR/Cas9 and regulated gene expression. The module also addresses the process of data interpretation including statistical analysis.
(Language of instruction: English)

Learning Outcomes
  1. Describe the history and the development of molecular biology techniques
  2. Explain advanced molecular biological techniques, their applications and limitations
  3. Identify suitable molecular biology methodologies to address a given scientific question
  4. Evaluate the advantages as well as the limitations of a given methodology
  5. Analyse and critically interpret data generated using molecular biology approaches
  6. Produce short analytical reports based on analysis of experimental molecular biology data
Assessments
  • Continuous Assessment (100%)
Teachers
Reading List
  1. "Molecular Cloning" by Michael R. Green, Joseph Sambrook
    ISBN: 9781936113422.
    Publisher: Cold Spring Harbor Laboratory Pr
  2. "Molecular Biology Techniques, Third Edition" by Sue Carson, Heather Miller, D. Scott Witherow
    ISBN: 9780123855442.
    Publisher: Academic Press
The above information outlines module BI5104: "Advanced Technologies in Cellular and Molecular Biology II" and is valid from 2016 onwards.
Note: Module offerings and details may be subject to change.