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Course Module Information
Course Modules
BME5100: Advanced Computational Biomechanics
Semester 1 | Credits: 5
This module entails the study of advanced computational technices and analytical methods in the field of biomechanics. Students will study the following topics: Finite deformation kinematics; Isotropic hyperelasticity; Anisotropic hyperelasticity of arteries; Non-linear viscoelasticity of tendons; advanced constitutive laws for muscle and cell contractility; Metal plasticity and shape memory materials used in medical devices; Pressure dependent plasticity of bone; Non-Newtonian blood flow.
(Language of instruction: English)
Learning Outcomes
- Compute deformation gradients for a range of boundary conditions
- Derive and compute finite deformation strain tensors
- Determine hyperelastic constitutive laws from strain energy density functions.
- Derive, implement and calibrate an anisotropic hyperelastic formulation for arterial tissue.
- Derive and calibrate non-linear viscoelastic constitutive laws for soft tissue.
- Determine the role of hydrostatic pressure in the plastic yielding of trabecular bone
- Derive constitutive laws for stress fibres in biological cells based on kinetics of actin-myosin bonding.
- Perform a non-linear finite element analysis of the interaction between a stent and an anisotropic hyper-viscoelastic artery.
- Perform a simulation of the non-Newtonian flow of blood in arteries
Assessments
- Written Assessment (65%)
- Continuous Assessment (35%)
Teachers
- NOELLE GANNON:
Research Profile |
Email
- PATRICK MCGARRY:
Research Profile |
Email
Reading List
- "Nonlinear Solid Mechanics: A Continuum Approach for Engineering." by Author: Gerhard A. Holzapfel, Publisher: Wiley. ISBN: 978-0-471-82319-3
- "Nonlinear Finite Elements for Continua and Structures." by Authors: Belytschko, Liu, Moran. Publisher: Wiley. ISBN-13: 978-0471987741.
- "Cardiovascular Solid Mechanics: Cells, Tissues, and Organs." by Author: Jay. D. Humphrey. Publisher: Springer.
Note: Module offerings and details may be subject to change.