Principal Investigator Profile

Prof. John Morrison

Biography

John Morrison has been in post as Professor of Obstetrics & Gynaecology at National University of Ireland, Galway / Consultant Obstetrician & Gynaecologist at University College Hospital Galway since 1997. Before joining the National University of Ireland, Galway he worked at University College London as a Lecturer in  Obstetrics & Gynaecology and  Senior Registrar in Obstetrics & Gynaecology. He completed RCOG sub-specialty training in Feto-Maternal Medicine at University College London Hospital. Before that he was a clinical Registrar and Research Fellow at University of Cambridge Clinical School, Addenbrookes Hospital, Cambridge. He is a Consultant Obstetrician Gynaecologist with Western Health board at University College Hospital Galway and provides a sub-specialty clinical service in Feto-Maternal Medicine.

Link to own Web page:  http://www.nuigalway.ie/obsgyn/

Research Area:

1. Myometrial physiology
2. Pre-term labour
3. Pre-natal diagnosis and high-risk obstetrics

List of Publications:

Hehir MP, Moynihan AT, Glavey SV, Morrison JJ. Umbilical artery tone in maternal obesity.  Reprod Biol Endocrinol. 2009 Jan 22;7:6. PMID: 19161625 [PubMed - in process]

Fitzgibbon J, Morrison JJ, Smith TJ, O'Brien M. Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin. Reprod Biol Endocrinol. 2009 Jan 8;7:2.  PMID: 19133144 [PubMed - in process

O'Brien, M., Morrison, J.J., Smith, T.J.
Upregulation of PSCDBP, TLR2, TWIST1, FLJ35382, EDNRB, and RGS12 Gene Expression in Human Myometrium at Labor. Reproductive Sciences. 2008 May; 15(4):382-93. PMID:18497345 [PubMed - indexed for MEDLINE]

Slattery MM, Geary M, Morrison JJ. 
Obstetric antecedents for preterm delivery. Journal Perinatal Medicine. 2008;36(4):306-9. PMID: 18598119 [Pubmed - indexed for MEDLINE]

Hehir MP, Glavey SV, Moynihan AT, Morrison JJ. 
Uterorelaxant effect of ghrelin on human uterine contractility.  American Journal of Obstetrics & Gynaecology 2008 Mar;198(3):323.el-5. Epub 2008 Feb 21 PMID18177835 [PubMed - indexed for MEDLINE]

O'Brien, M., Flynn, D., Mullins, B., Morrison, J.J., Smith, T.J.
Expression of RHOGTPase regulators in human myometrium. Reproductive Biology and Endocrinology. 2008 Jan 11;6:1 PMID:18190708 [PubMed - indexed for MEDLINE]

Moynihan AT, Smith TJ, Morrison JJ. The Relaxant Effect of Nifedipine in Human Uterine Smooth Muscle and the BK(Ca) Channel.  American Journal of Obstetrics & Gynaecology. 2008 Feb;198(2):237.el-8. PMID18226634[PubMed - indexed for MEDLINE]

Lynch CM, Sexton DJ, Morrison JJ.  Obesity and mode of delivery in primagravid and multigravid women.  American Journal of Perinatology. 2008 Mar;25(3):163-7.Epub 2008 Feb 25. PMID18300188[PubMed - indexed for MEDLINE]

Hynes PG, Friel AM, Smith TJ, Morrison JJ.  b-Adrenoreceptor Subtype Expression in Human Placenta and Umbilical Arteries in Normal and Pre-Eclamptic Pregnancies.  Journal of Hypertension in Pregnancy. 2008;27(2):169-81. PMID: 18484422 [PubMed - indexed for MEDLINE]

Lirussi F, Rakotoniaina Z, Madani S, Goirand F, Breuiller-Fouche M, Leroy MJ, Sagot P, Morrison JJ, Dumas M, Bardou M.  ADRB3 adrenergic receptor is a key regulator of human myometrial apoptosis and inflammation during chorioamnionitis.Journal of Biology Reproduction. 2008 Mar;78(3):497-505. Epub 2007 Nov 7. PMID: 17989355 [PubMed - indexed for MEDLINE]

Moynihan AT, Hehir MP, Sharkey A, Robson S, Europe-Finner GN, Morrison JJ
Histone deacetylase inhibitors and a functional potent in hibitory effect on human uterine contractility. American Journal of Obstetrics & Gynaecology. May 2. 2008 Aug;199(2):167.e1-7PMID: 18455134 [PubMed - indexed for MEDLINE]

O'Brien M, Morrisson JJ, Smith TJ. Expression of prothrombin and protease activated receptors in human myometrium during pregnancy and labour. Biology of Reproduction 2008 Jan;78(1):20-6. Epub 2007 Sep 26. 10.1095/biolreprod.107.062182. PMID: 17901076. [PubMed - Indexed for MEDLINE]

Friel AM, Hynes PG, Sexton DJ, Smith TJ, Morrison JJ. Expression Levels of mRNA for Rho A/ Rho kinase and its role in isoprostane induced vasoconstriction of human placental and maternal vessels. Journal of Reproductive Sciences  2008 Feb;15(2):179-88. Epub 2007 Dec 18. PMID: 18089586 [PubMed - indexed for MEDLINE]

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