HRB Clinical Research Facility Galway Publications List

2017

Clase, C.M, Barzilay, J, Gao, P, Smyth, A, Schmieder, R.E, Tobe, S, Teo, K.K, Yusuf, S, Mann, J.F.E. 'Acute change in glomerular filtration rate with inhibition of the renin-angiotensin system does not predict subsequent renal and cardiovascular outcomes.' Kidney International. Vol. 91, Iss. 3. March 2017. Pp 683-690

2016

Smyth, A, O'Donnell, M, Lamelas, P, Teo, K, Rangarajan, S, Yusuf, S, on behalf of the INTERHEART investigators. 'Physical activity and anger or emotional upset as triggers of acute myocardial infarction. The INTERHEART study.' Circulation. 2016; 134:1059-1067. Doi: 10.1161/CIRCULATIONAHA.116.023142

O'Dea, A, Tierney, M, Danyliv, A, Glynn, LG, McGuire, BE, Carmody, LA, Newell, J, Dunne, FP (2016) 'Screening for gestational diabetes mellitus in primary versus secondary care: The clinical outcomes of a randomised controlled trial'. Diabetes Research And Clinical Practice, 117 :55-63 [DOI] [Details]

Smyth, A, Griffin, M, Yusuf, S, Mann, J.F.E, Reddan, D, Canavan, M, Newell, J, O'Donnell, M. 'Diet and major renal outcomes: A prospectove cohort study. The NIH-AARP diet and health study.' Journal of Renal Nutrition. Vol. 26, Iss. 5, September 2016. Pp 288-298

Mente, A, O'Donnell, M, Rangarajan, S, Dagenais, G, Lear, S, McQueen, M, Diaz, R, Avezum, A, Lopez-Jaramillo, P, Lanas, F, Wei, L, Yin, L, Sun, Y, Lei, R, Iqbal, RS, Mony, P, Yusuf, R, Yusoff, K, Szuba, A, Oguz, A, Rosengren, A, Bahonar, A, Yusufali, A, Schutte, AE, Chifamba, J, Mann, JFE, Anand, SS, Teo, K, Yusuf, S, PURE Investigator, EPIDREAM Investigator, TARGET TRANSCEND Investigator. 'Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies.' The Lancet. July 2016. Vol. 388. Pp 465-475. doi: 10.1016/S0140-6736(16)30467-6

Banerjee, A, Khandelwal, S, Nambiar, L, Saxena, M, Peck, V, Moniruzzaman, M, Rocha Faria Neto, J, Curi Quinto, K, Smyth, A, Leong, D, Werba, J.P. 'Health system barriers and facilitators to medication adherence for the secondary prevention of cardiovascular disease: a systematic review.' Open Heart 2016. 3: e000438. doi:10.1136/openhrt-2016-000438

Murphy, PJ, Mc Sharry, J, Casey, D, Doherty, S, Gillespie, P, Jaarsma, T, Murphy, AW, Newell, J, O'Donnell, M, Steinke, EE, Toomey, E, Byrne, M. 'Sexual counselling for patients with cardiovascular disease: protocol for a pilot study of the CHARMS sexual counselling intervention.' BMJ Open. January 2016. Vol. 6. doi: 10.1136/bmjopen-2016-011219

2015

Smyth A, Teo KK, Rangarajan S, O'Donnell M, Zhang X, Rana P, Leong DP, Dagenais G, Seron P, Rosengren A, Schutte AE, Lopez-Jaramillo P, Oguz A, Chifamba J, Diaz R, Lear S, Avezum A, Kumar R, Mohan V, Szuba A, Wei L, Yang W, Jian B, McKee M, Yusuf S; PURE Investigators (2015). 'Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study" The Lancet. 2015 Sep 16. pii: S0140-6736(15)00235-4. doi: 10.1016/S0140-6736(15)00235-4.

Murphy AW, Cupples ME, Murphy E, Newell J, Scarrott C, Vellinga A, Gillespie P, Byrne M, Smith SM (2015) 'Six-year follow-up of the SPHERE RCT: secondary prevention of heart disease in general practice'. BMJ Open

Healy, D, Clarke-Moloney, M, Gaughan, B, O'Daly, S, Hausenloy, D, Sharif, F, Newell, J, O'Donnell, M, Grace, P, Forbes, JF, Cullen, W, Kavanagh, E, Burke, P, Cross, S, Dowdall, J, McMonagle, M, Fulton, G, Manning, BJ, Kheirelseid, EAH, Leahy, A, Moneley, D, Naughton, P, Boyle, E, McHugh, S, Madhaven, P, O'Neill, S, Martin, Z, Courtney, D, Tubassam, M, Sultan, S, McCartan, D, Medani, M, Walsh, S (2015) 'Preconditioning Shields Against Vascular Events in Surgery (SAVES), a multicentre feasibility trial of preconditioning against adverse events in major vascular surgery: study protocol for a randomised control trial'. Trials, 16

Alvarez-Iglesias, A., Newell, J., Scarrott, C. and Hinde, J. (2015) 'Summarising censored survival data using the mean residual life function'. Statistics In Medicine, 34 :1965-1976

O'Donnell, M, Mente, A, Yusuf, S (2015) 'Sodium Intake and Cardiovascular Health'. Circulation research, 116 :1046-1057

John Newell, Paul Korir, Brian Moore & Charles Pedlar (2015) 'App for the calculation of blood lactate markers'. Journal Of Sports Sciences, 33 (6):568-569

Prince, MJ, Wu, F, Guo, YF, Robledo, LMG, O'Donnell, M, Sullivan, R, Yusuf, S (2015) 'The burden of disease in older people and implications for health policy and practice'. Lancet, 385 :549-562

Bohm, M, Schumacher, H, Leong, D, Mancia, G, Unger, T, Schmieder, R, Custodis, F, Diener, HC, Laufs, U, Lonn, E, Sliwa, K, Teo, K, Fagard, R, Redon, J, Sleight, P, Anderson, C, O'Donnell, M, Yusuf, S (2015) 'Systolic Blood Pressure Variation and Mean Heart Rate Is Associated With Cognitive Dysfunction in Patients With High Cardiovascular Risk'. Hypertension, 65 :651-336

2014

O’Shea, E., Devane, D., Cooney, A., Casey, D., Jordan, F., Hunter, A., Newell, J., Murphy, K. (2014). The impact of reminiscence on the quality of life of residents with dementia in long-stay care. International Journal of Geriatric Psychiatry. doi:10.1002/gps.4099

A Loftus, BG Loftus, I Ó Muircheartaigh, J Newell, C Scarrott, S Jennings (2014). Acute Childhood Asthma in Galway City from 1985-2005: Relationship to Air Pollution and Climate. Irish Medical Journal, vol 107, Issue 7, page 198:204.

Gillespie P, Kelly L, Hurley L, Garrow AP, Glynn LG, McIntosh C, Dinneen SF. The effect of foot ulcers on costs of care for diabetes in Ireland. The Diabetic Foot 2014 (in press).

Conway R, Coughlan RJ, Low C, O'Donnell MJ, Carey JJ. Reply. Arthritis Rheumatol. 2014 Sep;66(9):2642. doi: 10.1002/art.38732.

Wallace TA, Downey RF, Seufert CJ, Schetter A, Dorsey TH, Johnson CA, Goldman R, Loffredo CA, Yan P, Sullivan FJ, Giles FJ, Wang-Johanning F, Ambs S, Glynn SA. Elevated HERV-K mRNA expression in PBMC is associated with a prostate cancer diagnosis particularly in older men and smokers. Carcinogenesis. 2014 Sep;35(9):2074-83. doi: 10.1093/carcin/bgu114. Epub 2014 May 23. PMID: 24858205 [PubMed - in process]

Mente A, O'Donnell MJ, Rangarajan S, McQueen MJ, Poirier P, Wielgosz A, Morrison H, Li W, Wang X, Di C, Mony P, Devanath A, Rosengren A, Oguz A, Zatonska K, Yusufali AH, Lopez-Jaramillo P, Avezum A, Ismail N, Lanas F, Puoane T, Diaz R, Kelishadi R, Iqbal R, Yusuf R, Chifamba J, Khatib R, Teo K, Yusuf S; PURE Investigators. Association of urinary sodium and potassium excretion with blood pressure. N Engl J Med. 2014 Aug 14;371(7):601-11. doi: 10.1056/NEJMoa1311989.

Cheng RY, Basudhar D, Ridnour LA, Heinecke JL, Kesarwala AH, Glynn S, Switzer CH, Ambs S, Miranda KM, Wink DA. Gene expression profiles of NO- and HNO-donor treated breast cancer cells: insights into tumor response and resistance pathways. Nitric Oxide. 2014 Aug 19. pii: S1089-8603(14)00277-8. doi: 10.1016/j.niox.2014.08.003. [Epub ahead of print]. PMID: 25153034 [PubMed - as supplied by publisher]

Dennedy MC, Rizza RA, Dinneen SF. Classification and Diagnosis of Diabetes Mellitus. In: Endocrinology, 7th Edition. Jameson JL, DeGroot LJ, editors. WB Saunders 2014 (in press)

Hynes L, Byrne M, Dinneen SF, McGuire B, O’Donnell M, McSharry J. Barriers and facilitators associated with attendance at hospital diabetes clinics among young adults (15-30) with Type 1 diabetes mellitus: A systematic review. Paediatric Diabetes 2014 [Epub ahead of print] doi: 10.1111/pedi.12198.

Canavan M, Smyth A, Bosch J, Jensen M, McGrath ER, Mulkerrin EC, O'Donnell MJ. Does Lowering Blood Pressure With Antihypertensive Therapy Preserve Independence in Activities of Daily Living? A Systematic Review. Am J Hypertens. 2014 Aug 25. pii: hpu131. [Epub ahead of print]

Gillespie P, O’Shea E, O’Hara MC, Dinneen SF. Cost effectiveness of group follow-up after structured education for type 1 diabetes: a cluster randomised controlled trial. Trials 2014:15:227

Casey R, O’Hara MC, Cunningham A, Wall D, Geoghegan R, Hynes L, McGuire B, Gately M, Dinneen SF. Young adult diabetes care in the West of Ireland: an audit of hospital practice. QJM 2014 [Epub ahead of print] doi: 10.1093/qjmed/hcu103

O Flatharta T, Khan A, Walsh T, O'Donnell M, O'Keeffe ST. Advance preferences regarding thrombolysis in patients at risk for stroke: a cross-sectional study. QJM. 2014 Jul 4. pii: hcu142. [Epub ahead of print]

Curtis R, Groarke A, Sullivan F. Stress and self-efficacy predict psychological adjustment at diagnosis of prostate cancer. Sci Rep. 2014 Jul 4;4:5569. doi: 10.1038/srep05569. PMID: 24993798 [PubMed - in process]

Hayes S, Hogan M, Dowd H, Doherty E, O'Higgins S, Nic Gabhainn S, MacNeela P, Murphy AW, Kropmans T, O'Neill C, Newell J, McGuire E. Comparing the clinical-effectiveness and cost-effectiveness of an internet-delivered Acceptance and Commitment Therapy (ACT) intervention with a waiting list control among adults with chronic pain: study protocol for a randomised controlled trial. BMJ Open. 2014 Jul 2;4(7):e005092. doi: 10.1136/bmjopen-2014-005092.

Casey M, Hayes PS, Glynn F, ÓLaighin G, Heaney D, Murphy AW, Glynn LG. Patients’ experiences of using a smartphone application to increase physical activity in primary care: the SMART MOVE qualitative study. British Journal of General Practice 2014; 64(625):e500-8

Casey D, Meehan B, O’Hara MC, 4, Byrne M, Dinneen SF and Murphy K. A mixed methods study exploring the factors and behaviours that impact on glycaemic control following a structured education programme: the Irish DAFNE Study. Journal of Mixed Methods Research 2014; in press.

Glynn LG, Hayes PS, Casey M, Glynn F, Alvarez-Iglesias A, Newell J, OLaighin G, Heaney D, O'Donnell M, Murphy AW. Effectiveness of a smartphone application to promote physical activity in primary care: the SMART MOVE randomised controlled trial. Br J Gen Pract. 2014 Jul;64(624):e384-91. doi: 10.3399/bjgp14X680461.

Smyth A, Dunkler D, Gao P, Teo KK, Yusuf S, O'Donnell MJ, Mann JF, Clase CM. The relationship between estimated sodium and potassium excretion and subsequent renal outcomes. Kidney Int. 2014 Jun 11. doi: 10.1038/ki.2014.214. [Epub ahead of print]

Sexton DJ. How should we modify recommended renin-angiotensin-aldosterone system inhibition when facing the cardiorenal syndrome? Circ Heart Fail. 2014 May;7(3):536. doi: 10.1161/CIRCHEARTFAILURE.113.000843.

Mente A, O'Donnell MJ, Yusuf S. The population risks of dietary salt excess are exaggerated. Can J Cardiol. 2014 May;30(5):507-12. doi: 10.1016/j.cjca.2014.02.003. Epub 2014 Feb 13.

Downey RF, Sullivan FJ, Wang-Johanning F, Ambs S, Giles FJ, Glynn SA. Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice? Int J Cancer. 2014 May 29. doi: 10.1002/ijc.29003. [Epub ahead of print] PMID: 24890612 [PubMed - as supplied by publisher]

Gallagher D, Jordan V, Gillespie P, Cullinan J, Dinneen SF. Distance as a Risk Factor for Amputation in Patients with Diabetes: A Case-Control Study. Ir Med J 2014;107(4):107-109.

Conway R, Low C, Coughlan RJ, O'Donnell MJ, Carey JJ. Methotrexate and lung disease in rheumatoid arthritis: a meta-analysis of randomized controlled trials. Arthritis Rheumatol. 2014 Apr;66(4):803-12. doi: 10.1002/art.38322.

Heinecke JL, Ridnour LA, Cheng RY, Switzer CH, Lizardo MM, Khanna C, Glynn SA, Hussain SP, Young HA, Ambs S, Wink DA. Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6323-8. doi: 10.1073/pnas.1401799111. Epub 2014 Apr 14. PMID: 24733928 [PubMed - indexed for MEDLINE]

Waters PS, Dwyer RM, Brougham C, Glynn CL, Wall D, Hyland P, Duignan M, McLoughlin M, Newell J, Kerin MJ. Impact of tumour epithelial subtype on circulating microRNAs in breast cancer patients. PLoS One. 2014 Mar 13;9(3):e90605. doi: 10.1371/journal.pone.0090605. eCollection 2014.

Teo KK, Pfeffer M, Mancia G, O'Donnell M, Dagenais G, Diaz R, Dans A, Liu L, Bosch J, Joseph P, Copland I, Jung H, Pogue J, Yusuf S; Aliskiren Prevention of Later Life Outcomes trial Investigators. Aliskiren alone or with other antihypertensives in the elderly with borderline and stage 1 hypertension: the APOLLO trial. Eur Heart J. 2014 Jul;35(26):1743-51. doi: 10.1093/eurheartj/ehu079. Epub 2014 Mar 9.

Mente A, O'Donnell MJ, Dagenais G, Wielgosz A, Lear SA, McQueen MJ, Jiang Y, Xingyu W, Jian B, Calik KB, Akalin AA, Mony P, Devanath A, Yusufali AH, Lopez-Jaramillo P, Avezum A Jr, Yusoff K, Rosengren A, Kruger L, Orlandini A, Rangarajan S, Teo K, Yusuf S. Validation and comparison of three formulae to estimate sodium and potassium
excretion from a single morning fasting urine compared to 24-h measures in 11 countries. J Hypertens. 2014 May;32(5):1005-14; discussion 1015. doi: 10.1097/HJH.0000000000000122.

Zafar H, Ullah I, Dinneen K, Matiullah S, Hanley A, Leahy MJ, Sharif F. Evaluation of hemodynamically severe coronary stenosis as determined by fractional flow reserve with frequency domain optical coherence tomography measured anatomical parameters. J Cardiol. 2014 Jul;64(1):19-24. doi: 10.1016/j.jjcc.2013.11.009. Epub 2013 Dec 22.

Hart RG, Diener HC, Coutts SB, Easton JD, Granger CB, O'Donnell MJ, Sacco RL, Connolly SJ; Cryptogenic Stroke/ESUS International Working Group. Embolic strokes of undetermined source: the case for a new clinical construct. Lancet Neurol. 2014 Apr;13(4):429-38. doi: 10.1016/S1474-4422(13)70310-7.

O'Dwyer ME, Swords R, Nagler A, McMullin MF, le Coutre PD, Langabeer SE, Alvarez-Iglesias A, Fan H, Woodman RC, Giles FJ, Conneally E. Nilotinib 300 mg BID as frontline treatment of CML: prospective analysis of the Xpert BCR-ABL monitor system and significance of 3-month molecular response. Leuk Res. 2014 Mar;38(3):310-5. doi: 10.1016/j.leukres.2013.11.016. Epub 2013 Dec 1.

Mohammad A, Lohan D, Bergin D, Mooney S, Newell J, O'Donnell M, Coughlan RJ, Carey JJ. The prevalence of vertebral fracture on vertebral fracture assessment imaging in a large cohort of patients with rheumatoid arthritis. Rheumatology (Oxford). 2014 May;53(5):821-7. doi: 10.1093/rheumatology/ket353. Epub 2013 Nov 18.

Mohammad A, Lohan D, Bergin D, Mooney S, Newell J, O' Donnell M, Amin S, Coughlan RJ, Carey JJ. Vertebral fracture assessment-detected abdominal aortic calcification and cardiovascular disease in rheumatoid arthritis. Semin Arthritis Rheum. 2014 Apr;43(5):632-7. doi:10.1016/j.semarthrit.2013.09.007. Epub 2013 Oct 5.

Mohammad A, Lohan D, Bergin D et al. The prevalence of aortic calcification on vertebral fracture assessment imaging among patients with rheumatoid arthritis. J Clin Densitom 2014;17:72-77.

Smyth A, O'Donnell MJ, Yusuf S et al. Sodium Intake and Renal Outcomes: A Systematic Review. Am Hypertens2014.

Canavan M, Glynn LG, Smyth A, Mulkerrin EC, Murphy AW, Mulqueen J, McGrath ER, O'Donnell MJ. Vascular risk factors, cardiovascular disease and functional impairment in community-dwelling adults. Gerontology 2014; DOI: 10.1159/000356744

Robinson S, Canavan M, O'Donnell MJ, Mulkerrin E. Vitamin D supplementation-clarity required regarding treatment regimens and target plasma levels. QJM 2014;107:327-329.

Feigin VL, Forouzanfar MH, Krishnamurthi R et al. Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet 2014;383:245-254.

Liew A, Eikelboom JW, O'Donnell M. Extended-duration new oral anticoagulants for venous thromboprophylaxis in patients undergoing total hip arthroplasty: a meta-analysis of the randomized controlled trials. J Thromb Haemost 2014;12:107-109.

McGrath ER, Eikelboom JW, Kapral MK, O'Donnell MJ. Novel oral anticoagulants: a focused review for stroke physicians. Int J Stroke 2014;9:71-78.

Feigin, VL,Forouzanfar, MH,Krishnamurthi, R,Mensah, GA,Connor, M,Bennett, DA,Moran, AE,Sacco, RL,Anderson, L,Truelsen, T, O'Donnell, M,Venketasubramanian, N,Barker-Collo, S,Lawes, CMM,Wang, WZ,Shinohara, Y,Witt, E,Ezzati, M,Naghavi, M,Murray, C (2014) 'Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study 2010'. Lancet, 383 :245-255.

Duane, S., Callan, A., Galvin, S., Murphy, A. W., Domegan, C., O'Shea, E., Cormican, M., Bennett, K., O'Donnell, M. and Vellinga, A. (2014) 'Supporting the Improvement and Management of Prescribing for urinary tract infections (SIMPle): Protocol for a cluster randomised trial'. Trials 2013, 14:441 doi:10.1186/1745-6215-14-441

O'Dea A, Infanti J, Gillespie P, Tummon O, Fanous S, Glynn L, McGuire B, Newell J, Dunne F (2014) 'The uptake, clinical and cost effectiveness of screening for gestational diabetes mellitus (GDM) in primary versus secondary care: study protocol for a randomised controlled trial'. Trials, .

2013

Conway R, Low C, Coughlan RJ, O'Donnell MJ, Carey JJ. Methotrexate and lung disease in rheumatoid arthritis - A meta-analysis of randomized controlled trials. Arthritis Rheum. 2013 Dec 24. doi: 10.1002/art.38322.

Hurley L, Kelly L, Garrow AP, Glynn LG, McIntosh C, Alvarez-Iglesias A, Avalos G, Dinneen SF. A prospective study of risk factors for foot ulceration: The West of Ireland Diabetes Foot Study. QJM 2013 Dec;106(12)1103-10. doi:10.1093/qjmed/hct182

Mohammad A, Aamir MU, Mooney S, Coughlan RJ, Carey JJ. Appropriateness of referrals to a tertiary referral centre for bone mineral density testing. Ir J Med Sci. 2013 Nov 30.

McGrath ER, Kapral MK, Fang J et al. Association of atrial fibrillation with mortality and disability after ischemic stroke. Neurology 2013;81:825-832.

Liew A, Eikelboom JW, O'Donnell M, Hart RG. Assessment of anticoagulation intensity and management of bleeding with old and new oral anticoagulants. Can J Cardiol 2013;29:S34-S44.

O'Donnell M, Yusuf S. Risk factors for stroke in Tanzania. Lancet Glob Health. 2013 Nov;1(5):e241-2. doi: 10.1016/S2214-109X(13)70097-4. Epub 2013 Oct 24.

O'Donnell, M,de Siun, A,O'Mullane, M,Smith, D,Bradley, C,Finucane, FM,Dinneen, SF (2013). "Differences in the structure of outpatient diabetes care between endocrinologist-led and general physician- led services". BMC Health Services Research

Khan S, Brougham CL, Ryan J, Sahrudin A, O'Neill G, Wall D, Curran C et al (2013). miR-379 Regulates Cyclin B1 Expression and Is Decreased in Breast Cancer. (A. Alisi, Ed.)PLoS ONE, 8(7), e68753. doi:10.1371/journal.pone.0068753

Glynn, L. G., Hayes, P. S., Casey, M., Glynn, F., Alvarez-Iglesias, A., Newell, J., ÓLaighin, G., et al. (2013). SMART MOVE - a smartphone-based intervention to promote physical activity in primary care: study protocol for a randomized controlled trial. Trials, 14(1), 157. doi:10.1186/1745-6215-14-157

Mohammad A, Carey JJ, Storan E, Scarry M, Coughlan RJ, Lee JM. High prevalence of fibromyalgia in patients with HFE-related hereditary hemochromatosis. J Clin Gastroenterol. 2013 Jul;47(6):559-64. doi: 10.1097/MCG.0b013e31826f7ad7.

O'Sullivan EP, Duignan J, O'Shea P, Griffin D, Dinneen SF. Evaluating hyperglycaemia in the hospitalised patient: towards an improved system for classification and treatment. Ir J Med Sci. 2013 Jul 2. PMID: 23817676.

Simpkin, A., & Newell, J. (2013). An additive penalty -Spline approach to derivative estimation. Computational Statistics & Data Analysis, 68, 30–43. doi:10.1016/j.csda.2013.06.007

Casey D, Murphy K, Devane D, Cooney A, McCarthy B, Mee L, Newell J, et al (2013). The effectiveness of a structured education pulmonary rehabilitation programme for improving the health status of people with moderate and severe chronic obstructive pulmonary disease in primary care: the PRINCE cluster randomised trial. Thorax, 1-7. doi:10.1136/thoraxjnl-2012-203103

Infanti JJ, Dunne FP, O'Dea A, Gillespie P, Gibson I, Glynn LG, Noctor E, Newell J, McGuire BE (2013). An evaluation of Croí MyAction community lifestyle modification programme compared to standard care to reduce progression to diabetes/pre-diabetes in women with prior gestational diabetes mellitus (GDM): study protocol for a randomised controlled trial. Trials, 14(121), 1-8

McDermott AM, Kidd P, Gately M, Casey R, Burke H, O'Donnell P, Kirrane F, Dinneen SF, O'Brien T. Restructuring of the Diabetes Day Centre: a pilot lean project in a tertiary referral centre in the West of Ireland. BMJ Qual Saf, 2013 May 30, 22(8):681-8 PMID: 23722055.

Ingoldsby H, Webber W, Wall D, Scarrott C, Newell J, Callagy C (2013). Prediction of Oncotype DX and TAILORx risk categories using histopathological and immunohistochemical markers by classification and regression tree (CART) analysis. The Breast, http://dx.doi.org/1-/1-16/j.breast.2013.04.008

Dinneen SF, O'Hara MC, Byrne M, Smith D, Courtney CH, McGurk C, Heller SR, Newell J, et al (2013). Group follow-up compared to individual clinic visits after structured education for type 1 diabetes: A cluster randomised controlled trial. Diabetes research and clinical practice, 100(1), 29-38. doi:10.1016/j.diabres.2013.01.017

Smyth A, Glynn LG, Murphy AW, Mulqueen J, Canavan M, Reddan DN, O'Donnell M. Mild chronic kidney disease and functional impairment in community-dwelling older adults. Age Ageing. 2013 Feb 24 [Epub ahead of print]

Linkins LA, Bates SM, Lang E, Kahn SR, Douketis JD, Julian J, Parpia S, Gross P, Weitz JI, Spencer FA, Lee AY, O'Donnell MJ, Crowther MA, Chan HH, Lim W, Schulman S, Ginsberg JS, Kearon C. Selective D-dimer testing for diagnosis of a first suspected episode of deep venous thrombosis: a randomised trial. Ann Intern Med. 2013 Jan 15; 158(2):93-100

Giles FJ, Mauro M, Hong F, Ortmann CE, McNeill C, Woodman RC, Hochhaus A, le Coutre PD, Saglio G. Rates of peripheral arterial occlusive disease in patients with chronic myeloid leukemia in the chronic phase treated with imatinib, nilotinib, or non-tyrosine kinase therapy: A retrospective cohort analysis. Leukemia 2013

Graux C, Sonet A, Maertens J, Duyster J, Greiner J, Chalandon Y, Martinelli G, Hess D, Heim D, Giles FJ, Gianella-Borradori A, Longerey B, Asatiani E, Rejeb N, Ottmann OG. A phase I study of two regimens of MSC1992371A, an oral inhibitor of aurora and other kinases, in patients with refractory hematologic malignancies. Leukemia Research 2013

DeAngelo D, Spencer A, Bhalla K, Prince HM, Fischer T, Kindler T, Giles FJ, Scott JW, Parker K, Liu A, Woo M, Atadja P, Ottmann OG. Phase 1a/2, 2-arm, multicenter, openlabel, dose-escalation study of oral panobinostat administered via 2 dosing schedules in adult patients with advanced hematologic malignancies. Leukemia 2013

Burke AJ, Sullivan FJ, Giles FJ , Glynn SA. The Yin and Yang of nitric oxide in cancer progression. Carcinogenesis 2013

Keane N, Freeman C, Swords R, Giles FJ . Elacytarabine: Lipid vector technology under investigation in acute myeloid leukemia. Expert Review of Hematology 2013

2012

Conway R, Coughlan RJ, Carey JJ. Adherence to uric acid treatment guidelines in a rheumatology clinic. Clin Rheumatol. 2012 Dec;31(12):1707-11. doi: 10.1007/s10067-012-2081-6. Epub 2012 Sep 5.

O'Donnell MJ, Fang J, D'Uva C, Saposnik G, Gould L, McGrath E, Kapral MK; Investigators of the Canadian Stroke Network. The PLAN score: a bedside prediction rule for death and severe disability following acute ischemic stroke. Arch Intern Med 2012 Nov 12;172(20): 1548-56

Waters PS, McDermott AM, Wall D, Heneghan HM, Miller N, Newell J, Kerin MJ and Dwyer RM. Relationship between circulating and tissue microRNAs in a murine model of breast cancer. PloS One 2012; 7(11):e50459 Epub Nov 30 PMID: 23226290

McGrath ER, O'Donnell MJ. Estimating treating effects in observational studies. Neurology. 2012 Oct 30;79(18):1844-5

Ottmann OG, Larson RA, Kantarjian HM, le Coutre PD, Baccarani M, Hochhaus A, Kim DW, Fan X, Novick S, Giles FJ. Phase II study of nilotinib in patients with relapsed or refractory Philadelphia chromosome–positive acute lymphoblastic leukemia. Leukemia 2012

Giles FJ, Yin OQP, Sallas WM, le Coutre PD, Woodman RC, Ottmann OG, Baccarani M, Kantarjian HM. Nilotinib population pharmacokinetics and exposure–response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia. European Journal Clinical Pharmacology 2012

Mee B, Gaffney E, Glynn SA, Donatello S, Carroll P, Connolly E, McGarrigle S, Boyle T, Flannery D, Sullivan FJ, McCormick P, Griffin M, Muldoon C, Fay J, O’Grady T, Kay E, Eustace J, Burke L, Sheikh AA, Finn S, Flavin R, Giles FJ. Development and progress of Ireland’s biobank network: Ethical, Legal and Social Implications (ELSI), standardised documentation, sample and data release and international perspective. Biopreservation and Biobanking 2012

Conway R(1), Bergin D, Carey JJ, Coughlan RJ. Tibial insufficiency fractures in rheumatoid arthritis: a new clinical sign. J Rheumatol. 2012 Sep;39(9):1893-4. doi: 10.3899/jrheum.120119.

Jabbour E, le Coutre PD, Cortes J, Giles F, Bhalla K, Pinilla-Ibarz J, Larson RA, Gattermann N, Ottmann O, Hochhaus A, Hughes T, Saglio G, Radich JP, Kim DW, Martinelli G, Reynolds J, Woodman RC, Baccarani M, Kantarjian HM. Prediction of outcome in patients with Philadelphia-positive chronic myeloid leukemia in chronic phase treated with nilotinib after imatinib resistance or intolerance. Leukemia 2012

Abraham J, Chua YX, Glover JM, Tyner JW, Loriaux MM, Kilcoyne A, Giles FJ, Nelon LD, Carew JS, Ouyang Y, Michalek JE, Pal R, Druker BJ, Rubin BP, Keller C. An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma. Biochemical & Biophysical ResearchCommunications. 426:363-368, 2012

Byrne, M., Newell J., Coffey N., O'Hara M.C., Cooke E., Dinneen SF. Predictors of quality of life gains among people with type 1 diabetes participating in the Dose Adjustment for Normal Eating (DAFNE) structured eduction programme. Diabetes Res Clin Pract (2012), http://dx.doi.org/10.1016/j.diabres.2012.09.017

Kheirelseid, E.A.H., Miller, N., Chang, K.H., Curran, C., Hennessey, E., Sheehan, M., Newell, J., Lemetre, C., Balls, G., Kerin, M.J. (2012). miRNA expressions in rectal cancer as predictors of response to neoadjuvant chemoradiation therapy. Int J Colorectal Dis. 10.1007/s00384-012-1549-9

Kheirelseid EA, Jumustafa H, Miller N, Curran C, Sweeney K, Malone C, McLaughlin R, Newell J, Kerin MJ( 2011) Bilateral breast cancer: analysis of incidence, outcome, survival and disease characteristics. Breast Cancer Res Treat. Feb;126(1):131-40.

Keane N, Freeman C, Swords R, Giles FJ. EPHA3 as a novel therapeutic target in the hematological malignancies. Expert Rev Hematol. 2012 Jun;5(3):325-40.

Conway R, Bergin D, Carey JJ, Coughlan RJ. A case of Behcet's syndrome presenting as focal myositis. Rheumatology (Oxford). 2012 Jun;51(6):975. doi: 10.1093/rheumatology/ker450. Epub 2012 Jan 23.

Mohammad A, Carey JJ, Storan E, Scarry M, Coughlan RJ, Lee JM. Prevalence of fibromyalgia among patients with chronic hepatitis C infection: relationship to viral characteristics and quality of life. J Clin Gastroenterol. 2012 May-Jun;46(5):407-12. doi: 10.1097/MCG.0b013e3182485528.

Giles FJ, Swords RT, Nagler A, Hochhaus A, Ottmann OG, Rizzieri DA, Talpaz M, Clark J, Watson P, Xiao A, Zhao B, Bergstrom D, Lecoutre PD, Freedman SJ, Cortes JE. MK-0457, an Aurora kinase and BCR-ABL inhibitor, is active in patients with BCR-ABL T315I leukaemia. Leukemia. 2012 Jul 9. doi: 10.1038/leu.2012.186. [Epub ahead of print].

Giles FJ, Coutre PL, Pinilla-Ibarz J, Larson RA, Gattermann N, Ottmann OG, Hochhaus A, Radich JP, Saglio G, Hughes TP, Martinelli G, Kim DW, Novick S, Gillis K, Fan X, Cortes J, Baccarani M, Kantarjian HM. Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukaemia in chronic phase: 48-month follow-up results of a phase II study. Leukemia. 2012 Jul 5. doi: 10.1038/leu.2012.181. [Epub ahead of print].

Giles F, Mahon FX, Gjertsen B, Swords R, Labar B, Turkina A, Rosti G. Developmental Therapeutics Consortium report on study design effects on trial outcomes in chronic myeloid leukaemia. Eur J Clin Invest. 2012 Mar 28. doi: 10.1111/j.1365-2362.2012.02675.x. [Epub ahead of print].

Giles FJ, Vey N, Rizzieri D, Ravandi F, Prebet T, Borthakur G, Jacobsen TF, Hagen S, Nilsson B, O'Brien S. Phase I and pharmacokinetic study of elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, in adults with refractory hematological malignancies. Leukemia. 2012 Jul;26(7):1686-9. doi: 10.1038/leu.2012.1. Epub 2012 Jan 6. No abstract available.

Giles FJ, Kantarjian HM, le Coutre PD, Baccarani M, Mahon FX, Blakesley RE, Gallagher NJ, Gillis K, Goldberg SL, Larson RA, Hochhaus A, Ottmann OG. Nilotinib is effective in imatinib-resistant or -intolerant patients with chronic myeloid leukaemia in blastic phase. Leukemia. 2012 May;26(5):959-62. doi: 10.1038/leu.2011.355. Epub 2011 Dec 13.

Burke AC, Swords RT, Kelly K, Giles FJ. Current status of agents active against the T315I chronic myeloid lekaemia phenotype. Expert Opin Emerg Drugs. 2011 Mar;16(1):85-103. Review.

Lansberg MG, O'Donnell MJ, Khatri P et al. Antithrombotic and thrombolytic therapy for ischemic stroke: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012;141:e601S-e636S.

Lawrence J, Pogue J, Synhorst D et al ( O'Donnell M). Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial. Lancet Neurol 2012;11:225-231.

Liew A, Eikelboom JW, O'Donnell M. Randomized controlled trials of new oral anticoagulants for stroke prevention in atrial fibrillation. Curr Opin Cardiol 2012;27:331-339.

Marzona I, O'Donnell M, Teo K et al. Increased risk of cognitive and functional decline in patients with atrial fibrillation: results of the ONTARGET and TRANSCEND studies. CMAJ 2012;184:E329-E336.

McGrath ER, Glynn LG, Murphy AW et al ( O'Donnell M). Preventing cardiovascular disease in primary care: role of a national risk factor management program. Am Heart J 2012;163:714-719.

McGrath ER, Kapral MK, Fang J et al ( O'Donnell M). Which Risk Factors Are More Associated With Ischemic Stroke Than Intracerebral Hemorrhage in Patients With Atrial Fibrillation? Stroke 2012.

Methodology of the global and regional burden of stroke study. Neuroepidemiology 2012;38:30-40. ( O'Donnell M)

O'Donnell M, Teo K, Gao P et al. Cognitive impairment and risk of cardiovascular events and mortality. Eur Heart J 2012.

Sobieraj-Teague M, Hirsh J, Yip G et al ( O'Donnell M). Randomized controlled trial of a new portable calf compression device (Venowave) for prevention of venous thrombosis in high-risk neurosurgical patients. J Thromb Haemost 2012;10:229-235.

2011

Abraham, J., Prajapati, S., Nishijo, K., Schaffer, B., Taniguchi, E., Kilcoyne, A., McCleish, A., Nelon, L., Giles, F., Efstratiadis, A., Legallo, R., Nowak, B., Rubin, B., Malempati, S., Keller, C. Evasion mechanisms to IGF1r inhibition in rhabdomyosarcoma. Molecular Cancer Therapeutics 2011

Abraham, J., Nelon, L.D., Kubicek, C.B., Kilcoyne, A., Hampton, S.T., Zarzabal, L.A., Giles, F. , Michalek, J.E., Rubin, B.P., Keller, C. Preclinical testing of Erlotinib in a transgenic alveolar rhabdomyosarcoma mouse model. Sarcoma 2011

Barzilay, J.I., Gao, P., O'Donnell, M., Mann, J.F., Anderson, C., Fagard, R., Probstfield, J., Dagenais, G.R., Teo, K., Yusuf, S.; ONTARGET and TRANSCEND Investigators. Albuminuria and decline in cognitive function: The ONTARGET/TRANSCEND studies. Arch Intern Med. 2011 Jan 24;171(2):142-50.

Burke, A.C., Swords, R.T., Kelly, K., Giles, F.J. (2011). Current status of agents active against the T315I chronic myeloid leukemia phenotype. Expert Opinion on Emerging Drugs 16 (1) 85-103.

Connolly, S.J., Eikelboom, J., Joyner C., Diener, H.-C., Hart, R., Golitsyn, S., Flaker, G., Avezum, A., Hohnloser, S.H., Diaz, R., Talajic, M., Zhu, J., Pais, P., Budaj, A., Parkhomenko, A., Jansky, P., Commerford, P., Tan, R.S., Sim, K.-H., Lewis, B.S., Van Mieghem, W., Lip, G.Y.H., Kim, J.H., Lanas-Zanetti, F., Gonzalez-Hermosillo, A., Dans, A.L., Munawar, M., O'Donnell, M., Lawrence, J., Lewis, G., Afzal, R., Yusuf, S. (2011). Apixaban in patients with atrial fibrillation. New England Journal of Medicine 364 (9):806-817.

Cortes, J.E., Hochhaus, A., le Coutre, P.D., Rosti, G., Pinilla-Ibarz, J., Jabbour, E., Gillis, K., Woodman, R.C., Blakesley, R., Giles, F.J. , Kantarjian, H.M., Baccarani, M. Minimal cross-intolerance with nilotinib in patients with chronic myeloid leukemia in chronic or accelerated phase who are intolerant to imatinib. Blood 2011.

Feil, S., Newell, J., Minogue, C., Paessler, H.H. (2011). The effectiveness of supplementing a standard rehabilitation program with superimposed neuromuscular electrical stimulation after anterior cruciate ligament reconstruction: a prospective, randomized, single-blind study. Am J Sports Med. 2011 Jun;39(6):1238-47.

Glynn, L. G., Valderas, J. M., Healy, P., Burke, E., Newell, J., Gillespie, P., Murphy, A. W. The prevalence of multimorbidity in primary care and its effect on health care utilization and cost. Family Practice 2011; doi: 10.1093/fampra/cmr013

Hallahan, B., Newell, J., Soares, J.C., Brambilla, P., Strakowski , S.M., Fleck, D.E., Kiesepp, T., Altshuler, L.L., Fornito, A., Malhi, G.S., McIntosh, A.M., Yurgelun-Todd, D.A., Labar, K.S., Sharma ,V., MacQueen, G.M., Murray, R.M., McDonald, C. (2011). Structural magnetic resonance imaging in bipolar disorder: An international collaborative mega-analysis of individual adult patient data. Biological Psychiatry 69 (4):326-335.

Kelly, K.R., Mahalingam, D., Medina, E., Smith, S., Padmanabhan, S., Bearss, D., O’Dwyer, M., Nawrocki, S.T., Giles, F.J. , Carew, J.S. The novel Pim kinase inhibitor SGI-1776 has potent activity in acute myeloid leukemia independent of FLT3 status and synergistically augments the efficacy of cytarabine. British Journal of Haematology 2011

Lancet, J.E., Ravandi, F., Ricklis, R.M., Cripe, L.D., Kantarjian, H.M., Giles, F.J., List, A.F., Chen, T., Allen, R.S., Fox, J.A., Michelson, G.C., Karp, J.E. A phase 1b study of voreloxin, an anticancer quinolone derivative, in patients with relapsed or refractory acute leukemia. Leukemia 2011

Lapusan, S., Vidriales, M.B.,Thomas, X., de Botton, S., Vekhoff, A., Tang, R., Dumontet, C., Morariu-Zamfir, R., Lambert, J.M., Ozoux, M.L., Poncelet, P., San Miguel, J.F ., Legrand, O., De Angelo, D., Giles, F.J. , Marie, J.P. Dose-escalation phase I studies of AVE9633, an anti CD33 antibody- maytansinoid conjugate, administered as a single agent by intravenous infusion to adult patients with relapsed or refractory CD33-positive acute myeloid leukemia. Investigational New Drugs 2011

Ma, W., Giles, F., Zhang, X., Wang, X., Zhang, Z., Lee, T.S., Yeh, C.H., Albitar, M. Three novel alternative splicing mutations in BCR-ABL1 detected in CML patients with resistance to kinase inhibitors. International Journal Laboratory Hematology 2011

McElwain, J., Simpkin, A., Newell, J. and Laffey, J. G. (2011), Determination of the utility of the Intubation Difficulty Scale for use with indirect laryngoscopes. Anaesthesia, 66: 1127–1133. doi: 10.1111/j.1365-2044.2011.06891.x

McGrath, E., O'Conghaile, A., Eikelboom, J.W., Dinneen, S.F., Oczkowski, C., O'Donnell, M.J. Validity of Composite Outcomes in Meta-Analyses of Stroke Prevention Trials: The Case of Aspirin. Cerebrovasc Dis 2011 May 11;32(1):22-7.

Murphy, K., Casey, D., Devane, D., Cooney, A., McCarthy, B., Mee, L., Ni Chúlain, M., Murphy, A. W., Newell, J., O' Shea, E. A cluster randomised controlled trial evaluating the effectiveness of a structured pulmonary rehabilitation education programme for improving the health status of people with chronic obstructive pulmonary disease (COPD): The PRINCE Study protocol. BMC Pulmonary Medicine 2011, 11:4.

O'Donnell, M.J., Fang, J., Mittleman, M.A., Kapral, M.K., Wellenius, G.A. Fine particulate air pollution (PM2.5) and the risk of acute ischemic stroke. Epidemiology 2011 May;22(3):422-31.

Raja Ali, R.A., Dooley, C., Comber, H., Newell, J., Egan, L. Clinical Features, Treatment, and Survival of Patients With Colorectal Cancer With or Without Inflammatory Bowel Disease (2011). Clinical Gastroenterology and Hepatology, Volume 9, Issue 7, 584-589.

Raju, N., Sobieraj-Teague, M., Hirsh, J., O'Donnell, M., Eikelboom, J. Effect of Aspirin on Mortality in the Prevention of Cardiovascular Disease. Am J Med 2011 May 16.

Ryan, J., Curran, C. E., Hennessy, E., Newell, J., Morris, J. C., Kerin, M. J., Dwyer, R.M. (2011). The Sodium Iodide Symporter (NIS) and Potential Regulators in Normal, Benign and Malignant Human Breast Tissue. PLoS ONE (2011) 6(1): e16023

Saposnik, G., Kapral, M.K., Liu, Y., Hall, R., O'Donnell, M., Raptis, S., Tu, J.V., Mamdani, M., Austin, P.C.. IScore: a risk score to predict death early after hospitalization for an acute ischemic stroke. Circulation 2011 February 22;123(7):739-49.

Qu, K.Z., Zhang, K., Ma, W., Li, H., Wang, X., Zhang, X., Giles, F., Lai, M., Afdhal, N.H., Albitar, M. Ubiquitin-Proteasome signature for detection of hepatocellular carcinoma. Journal Gastroenterology and Hepatology 26:751-758, 2011

2010

Anderson, J., Glynn, L.G., Newell. J., Iglesias, A. A., Reddan, D., Murphy, A. W. Chronic kidney disease and anaemia in cardiovascular disease: a high risk combination? Cardiodiabetes. 2010; 3 (2); 8-13.

Bansal, H., Bansal,S., Rao, M., Ying, W., Sang, J., Kelly, K., Swords, R.P., Foley, K.P., Barsoum, J.,Repasky, E., Giles, F.J., Lee, K.P., Padmanabhan, S.. Heat Shock Protein 90 regulates the expression of Wilm’s tumor 1 protein in myeloid leukemias. Blood 116, 4591-4599, 2010

Carew, J.S., Esquivel, J.A., Mahalingam, M., Olaya, C.M., Swords, R., Kelly, K., Giles, F.J., Nawrocki, S.T. Lucanthone: A novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis. Journal of Biological Chemistry. 2010

Curley. G., Laffey, J.G., Kavanagh, B.P. (2010). Ipsilateral transversus abdominis plane block provides effective analgesia after appendectomy in children: A randomized controlled trial. Anesth Analg. 2010 Oct;111(4):998-1003. Epub 2010 Aug 27

Dowlatshahi, D., O'Donnell, M., Sharma, M. (2010). Possible influence of stroke etiology on hemorrhagic transformation following thrombolysis in warfarin-treated patients. Archives of Neurology. 67 (11).

Eikelboom, J.W., O'Donnell, M., Yusuf, S., Diaz, R., Flaker, G., Hart, R., Hohnloser, S., Joyner, C., Lawrence, J., Pais, P., Pogue, J., Synhorst, D., Connolly, S.J. Rationale and design of AVERROES: apixaban versus acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin K antagonist treatment. Am Heart J 2010 March;159(3):348-53.

Fisher. T., Stone,R.M., DeAngelo, D., Galinsky, I., Estey, E., Cohen, P., Fox, E., Ehninger, G., Feldman, E.J., Schiller, G.J., Klimek, V.M., Nimer, S.D., Gilliland, D.G., Wong, Y.F., Massimini, G., Giles, F.J. A Phase IIB trial of the putative FLT3 and mutlitargeted kinase inhibitor PKC412 (N-benzoylstaurosporine; Midostaurin) in patients with acute myeloid leukemia or high-risk myelodysplastic syndrome with either wild-type or mutated FLT3. Journal of Clinical Oncology 28; 4339-4345, 2010

Foran, E., Garrity-Park, M. M., Mureau, C., Newell, J., Smyrk, T. C., Limburg, P. J., et al. (2010). Upregulation of DNA methyltransferase - mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6. Molecular Cancer Research, 8(4): 471-481.

Giles, F.J., Rosti, G., Beris, P., Clark, R.E., Le Coutre, P., Mahon, F.-X., Steegmann, J.-L., Valent, P., Saglio, G. Nilotinib is superior to imatinib as first-line therapy of chronic myeloid leukemia: The ENESTnd study. Expert Review of Hematology 3 (6):665-673, 2010

Heneghan, H. M., Miller, N., Kelly, R., Newell, J., & Kerin, M. J. (2010). Systemic miRNA-195 differentiates breast cancer from other malignancies and is a potential biomarker for detecting noninvasive and early stage disease. Oncologist, 15(7), 673-682.

Heneghan, H. M., Miller, N., Lowery, A J., Sweeney, KJ ., Newell, J., Kerin, M J.. Circulating microRNAs as novel minimally invasive biomarkers for breast cancer. Ann Surg. 251 (3):499-505 2010.

Kantarjian, H.M., Giles, F.J., Greenberg, P.L., Paquette, R.L.,Wang, E.S., Gabrilove, J.L., Garcia-Manero, G., Hu, K., Franklin, J.L., Berger,D.P. Phase II study of romiplostim in patients with low- or Intermediate-risk myelodysplastic syndrome receiving azacitidine therapy. Blood 116 :3163-3170, 2010

Kantarjian, H.M., Giles, F.J.,Bhalla, K.P., Pinilla, J.,Larson, R.A.,Gattermann, N.,Ottmann, O., Hochhaus, A.,Radich, J.P.,Saglio, G.,Hughes, T.P.,Martinelli, G.,Kim, D.W.,Shou, Y., Gallagher, N.J.,Blakesley, R.,Baccarani, M.,Cortes, J.,le Coutre, P.D.Nilotinib, a potent and selective BCR-ABL inhibitor, is effective in patients with chronic myeloid leukemia in chronic phase following imatinib resistance or intolerance: 24-month follow-up results of a phase 2 study. Blood 2010

Kearon, C., O'Donnell, M. (2010). Should patients with stroke wear compression stockings to prevent venous thromboembolism? Annals of Internal Medicine. 153 (9): 610-611.

Kelly, K., Swords, R., Mahalingam, D., Giles, F. Optimizing outcomes in patients with chronic myeloid leukemia in chronic phase: comparative safety profiles of newer agents. Leukemia Lymphoma 51; 1399-1413, 2010

Kelly, K., Swords, R., Mahalingam, D., Nawrocki, S., Padmanabhan, S., Giles, F., Carew, S. The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukemia and significantly increases the efficacy of nilotinib. Journal of Cellular and Molecular Medicine 2010

Kheirelseid, E. A. H., Chang, K H., Newell, J., Kerin, M J., Miller, N. Identification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancer. BMC Molecular Biology, 2010, 11:12.

Linkins, L., O'Donnell, M., Julian, J.A., Kearon, C. (2010). Intracranial and fatal bleeding according to indication for long-term oral anticoagulant therapy. Journal of Thrombosis and Haemostasis 8 (10) 2201-2207.

Mita, M., Ricart, A., Mita, A., Romero, O., Tolcher, A., Desai, P., Hook, L., Zang, E., Okereke, C., Kelly, K., Giles, F., Rowinsky, E., Takimoto, C. Phase I study of E7820, an oral inhibitor of integrin α2 expression, with antiangiogenic properties, in patients with advanced malignancies. Clinical Cancer Research 2010

Oczkowski, C., O'Donnell, M. Reliability of proxy respondents for patients with stroke: a systematic review. J Stroke Cerebrovasc Dis 2010 September;19(5):410-6

O'Donnell, M.J., Denis, X., Liu, L., Zhang, H., Chin, S.L., Rao-Melacini, P., Rangarajan, S., Islam, S., Pais, P., McQueen, M.J., Mondo, C., Damasceno, A., Lopez-Jaramillo, P., Hankey, G.J., Dans, A.L., Yusoff, K., Truelsen, T., Diener, H.-C., Sacco, R.L., Ryglewicz, D., Czlonkowska, A., Weimar, C., Wang, X., Yusuf, S. (2010). Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study. The Lancet 376 (9735):112-123.

O'Donnell, M., Xavier, D., Diener, C., Sacco, R., Lisheng, L., Zhang, H., Pias, P., Truelsen, T., Chin, S.L., Rangarajan, S., Devilliers, L., Damasceno, A., Mondo, C., Lanas, F., Avezum, A., Diaz, R., Varigos, J., Hankey, G., Teal, P., Kapral, M., Ryglewicz, D., Czlonkowska, A., Skowronska, M., Lopez-Jaramillo, P., Dans, T., Langhorne, P., Yusuf, S. Rationale and design of INTERSTROKE: a global case-control study of risk factors for stroke. Neuroepidemiology 2010;35(1):36-44.

Prajapati, S.I., Kilcoyne, A., Samano, A.K., Green, D.P., McCarthy, S.D., Blackman, B.A., Brady, M.M., Zarzabal, L.A., Tatiparthy, A.K., Sledz, T.J., Duong, T., Ohshima-Hosoyama, S., Giles, F.J., Michalek, J.E., Rubin, B.P., Keller, C. MicroCT-based virtual histology evaluation of preclinical medulloblastoma. Molecular Imaging Biology. 2010

van Rees Vellinga, T.E., Peters, R.J., Yusuf, S., Afzal, R., Chrolavicius, S., O'Donnell, M., Mehta, S.R., Pluta, W., Sacha, J., Eikelboom, J.W. Efficacy and safety of fondaparinux in patients with ST-segment elevation myocardial infarction across the age spectrum. Results from the Organization for the Assessment of Strategies for Ischemic Syndromes 6 (OASIS-6) trial. Am Heart J . 2010 Dec;160(6):1049-55

2009

Anderson, J., Glynn, L G., Newell, J., Iglesias, A A., Reddan, D. and Murphy, AW. The impact of renal insufficiency and anaemia on survival in patients with cardiovascular disease: a cohort study. BMC Cardiovascular Disorders 2009, 9:51doi:10.1186/1471-2261-9-51.

Carney J., McDonnell, J G., Ochana, A., Bhinder, R., Laffey, J G. The Transversus Abdominis Plane Block provides effective postoperative analgesia in patients undergoing total abdominal hysterectomy. Anesthesia and Analgesia 2008 Dec;107(6):2056-60.

Dinneen, S F., O' Hara, M C., Byrne, M., Newell, J., Daly, L., O' Shea, D., Smith, D., and Irish DAFNE Study Group. The Irish DAFNE Study Protocol: A cluster randomised trial of group versus individual follow-up after structured education for Type 1 diabetes. Trials 2009, 10:88

Glynn, L G., O'Riordan, C., MacFarlane, A., Newell, J., Iglesias, A A., Whitford, D., Cantillon, P., Murphy, A W. (2009) Research activity and capacity in primary healthcare: The REACH study: A survey. BMC Family Practice 2009, 10:33

Hogan, M J., Kelly, C A M., Verrier, D., Newell, J., Hasher, L., Robertson, I H. Optimal time-of-day and consolidation of learning in younger and older adults. Experimental Aging Research. 2009;35(1):107-28.

Malik, M A., Subramaniam, R., Maharaj C H., Higgins, B D., Harte, B H., Laffey, J G. A randomized trial of the Pentax AWS®, Glidescope® and Macintosh Laryngoscopes in patients at increased risk for difficult tracheal intubation. Br J Anaesthesia 2009 Nov;103(5):761-8. [PMID: 19783539]

Malik, M A., Subramaniam, R., Churasia, S., Maharaj, C H., Harte, B H., Laffey, J G. Tracheal intubation in patients with cervical spine immobilization: a comparison of the Airwayscope, LMA CTrach, and the Macintosh laryngoscopes. Br J Anaesth. 2009 May;102(5):654-61. Epub 2009 Mar 31

Malik, M A., Hassett, P., Carney, J., Higgins, B D., Harte, B H., Laffey, J G. A comparison of the Glidescope®,Pentax AWS®, and Macintosh laryngoscopes when used by novice personnel: A manikin study. Canadian Journal of Anesthesia. 2009;56(11):802-11.

Malik, M A., O'Donoghue, C., Carney, J., Maharaj, C H., Harte, B H., Laffey, J G. Comparison of the Glidescope®, the Pentax AWS®, and the Truview EVO2® with the Macintosh laryngoscope in experienced anaesthetists: A manikin study. British Journal of Anaesthesia. 2009;102(1):128-34.

Murphy, A W., Cupples, M E., Smith, S M., Byrne, S., Byrne, M C., Newell, J. Effect of tailored practice and patient care plans on secondary prevention of heart disease in general practice: cluster randomised controlled trial. BMJ 2009;339 b4220.

O’ Riordan, C., Glynn, L G., MacFarlane, A., Newell, J., Iglesias, A A., Whitford, D., Cantillon, P., Murphy, A W. Research activity and capacity in primary care. Forum 2009;26 (9):27-30.

Statistics for Sports and Exercise Science: A Practical Approach
John Newell, Tom Aitchison, Stanley Grant. Pearson Publishers, Oct 2009,
ISBN13: 9780132042543.

2008

Glynn, L G., Buckley, B., Reddan, D., Newell, J., Hinde, J., Dinneen, S F., Murphy, A W. Multimorbidity and risk among patients with established cardiovascular disease: a cohort study. British Journal of General Practice. 58(552):488-94, 2008 Jul.

Malik, M A., Maharaj, C H., Harte, B H., Laffey, J G. A Comparison of Macintosh, Truview EV02â, Glidescope® and Airwayscope® Laryngoscopes in Patients with Cervical Spine Immobilization. Br J Anae s2008; doi: 10.1093/bja/aen231