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Dr. Laoise McNamara

phone:    353 91 492251
fax:        353 91 563991
e-mail:    laoise.mcnamaranuigalway.ie

Research Interests

Mechanical characterisation of biological tissues
Bone cell biology
Mechanobiology
Bone tissue regeneration in vitro
Finite element modelling
Adaptive modelling of biological processes

Selected Publications

McNamara LM, Majeska RJ, Weinbaum S, Friedrich V, Schaffler MB, Attachment of osteocyte cell processes to the bone matrix, Anatomical Record, in press (2009).

Wang Y, McNamara LM, Mitchell B. Schaffler, Weinbaum S, Strain amplification and integrin based signalling in osteocytes, Journal of Musculoskeletal and Neuronal Interactions 8(4):332-334 (2008).

B.M. Mulvihill, McNamara LM, Prendergast PJ, Loss of trabeculae in osteoporotic cancellous bone by biomechanical means, J R Soc Interface 5(27):1243-53 (2008).

Wang Y, McNamara LM, Schaffler MB, Weinbaum S, A Model for the Role of Integrins in Flow Induced Mechanotransduction in Osteocytes, Proceedings of the National Academy of Sciences (PNAS) 104(40):15941-6 (2007).

McNamara LM, Prendergast PJ, Bone remodelling algorithms incorporating both strain and microdamage stimuli, Journal of Biomechanics, J Biomech. 2007; 40(6):1381-91 (2007).

B.M. Mulvihill, McNamara LM, Prendergast PJ, 2007, The effect of patient-specific bone remodeling rates on remodelling/repair in trabecular bone, III International congress on Computational Bioengineering

McNamara LM, Lyons CG, Ederveen AH, H. Weinans, Price CJ, Schaffler MB, Prendergast PJ, Strength of cancellous bone trabecular tissue from normal, ovarectomized and drug-treated rats over the course of ageing, BONE 39(2):392–400 (2006).

McNamara LM, Van der Linden JC, Weinans H, and Prendergast PJ, Stress-concentrating effect of resorption lacunae in trabecular bone, Journal of Biomechanics 39(4):734-41 (2006).

McNamara LM, Prendergast PJ and Schaffler MB, Bone tissue material properties are altered during Osteoporosis, Journal of Musculoskeletal and Neuronal Interactions 5(4):342-3 (2005).

McNamara LM, Prendergast PJ, Perforation of cancellous bone trabeculae by damage-stimulated remodelling at resorption pits: a computational analysis, European Journal of Morphology 42(1/2):99-109 (2005).

Book Chapters

McNamara LM, Bones of Contention, In: Perspectives in Design and Bioengeineering:, Edited by Simms, C.J. and Prendergast, P.J., 2008, ISBN-10: 0954858328

Lee TC, McHugh PE, O’Brien FJ, O’Mahoney D, Taylor D, Bruzzi M, Rackard SM, Kennedy OD, Mahony NJ, Harrison N, Lohfield S, Brennan O, Gleeson J, Hazenberg JG, Mullins L, Tyndyk M, McNamara LM, O’Kelly KU, Prendergast PJ, Bone for Life: Osteoporosis, Bone Remodelling and Computer Simulation, In Topics in Bio-Mechanical Engineering:, pp. 58-93. Edited by Prendergast PJ and McHugh PE, 2004, ISBN: 0954858301


    

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