Career history

2014, Professor of Pharmacology & Therapeutics, NUI Galway 
2004 - 2014, Senior Lecturer in Pharmacology & Therapeutics, NUI Galway 
2004-2005, Acting Head of Department of Pharmacology & Therapeutics, NUI Galway 
2002-2004, College Lecturer in Pharmacology, Galway 
1999-2002, Junior Lecturer in Pharmacology, Galway 
1993-1999, Fixed-term Lecturer in Pharmacology, Galway 
1988-1992, Researcher, Department of Pharmacology, Galway 
1988-1991, Ph.D (Neuropharmacology), Galway 
1980-1988, Researcher May and Baker Ltd., Dagenham, Essex, U.K.

Research Interests 
Current areas of research include the mechanisms of action of antidepressants using preclinical models, developing alternatives to laboratory animals for acute toxicity assessment, and the effects of exposure to antidepressants and amphetamines in preclinical models of development. This research has resulted in over 100 peer-reviewed publications.  Research links have been established with other national and international centres, both within academic and industrial spheres. This research has been recognised by the awarding of a D.Sc. (published work) in 2012 by the National University of Ireland. These research activities have been funded from a variety of competitive sources, including the Programme for Third Level Institutions, the Health Research Board, Science Foundation Ireland, the Wellcome Trust, the Irish Research Council and the NUI, Galway Millennium Grant Scheme.

Recent publications  
Simpson, J., and Kelly, J.P. (2012): The effects of isolated and enriched housing conditions on baseline and drug-induced behavioural responses in the male rat. Behav Brain Res. 234: 175-183.

Simpson, J., Bree, D. and Kelly, J.P. (2012): Effect of early life housing manipulation on baseline and drug-induced behavioural responses on neurochemistry in the male rat. Prog Neuropsychopharmacol Biol Psychiatry 37: 252-263.

Simpson, J., Ryan, C., Curley, A., Mulcaire, J and Kelly, J.P. (2012): Sex differences in baseline and drug-induced behavioural responses in classical behavioural tests. Prog Neuropsychopharmacol Biol Psychiatry 37: 227-236.

Simpson, J. and Kelly, J.P. (2012): An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat. Behav Brain Res. 229: 289-300 .

Roche, M., Kerr, D.M., Hunt, S.P. and Kelly, J.P. (2012): Neurokinin-1 receptor deletion modulates behavioural and neurochemical alterations in an animal model of depression. Behav. Brain Res. 228: 91-98.

Butler, R.K., Ford, G.K., Hogan, M., Roche, M., Doyle, K.M., Kelly, J.P., Kendall, D.A., Chapman, V. and Finn, D.P. (2012): Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase. J. Psychopharmacol. 26: 83-91.

Kelly, J.P. (2011): Cathinone derivatives: a review of their chemistry, pharmacology and toxicology. Drug Test Anal. 3: 439-453.

Simpson, J., and Kelly, J.P. (2011): The impact of environmental enrichment in laboratory rats--behavioural and neurochemical aspects. Behav Brain Res. 12: 246-264.

 

Book: Kelly J. (2010): Principles of CNS Drug Development: from test tube to patient. Wiley and Sons, UK

Caulfield C, Kelly J, Jones B, Worrall S, Conlon L, Palmer T and Cassidy J. (2009): The Experimental Induction of Leukoencephalomyelopathy in Cats. Vet Pathol. 46: 1258-1269.

 

Uma, S, Kelly, J.P. and Rajasekaran. S.K. (2008): An investigation of the value of the Tetrahymena pyriformis as a test organism for assessing the acute toxicity of antidepressants. Biomed. Res. 19: 37-40.

Caulfield, C.D., Cassidy, J.P. and Kelly J.P. (2008): Effects of gamma irradiation and pasteurization on the nutritive composition of commercially available animal diets. J Am Assoc Lab Anim Sci. 47: 61-6.

McDermott, C. and Kelly, J.P. (2008): Comparison of the behavioural pharmacology of the Lister-Hooded with 2 commonly utilised albino rat strains. Prog Neuropsychopharmacol Biol Psychiatry. 32: 1816-1823.

Roche, M., Shanahan, E., Harkin, A. and Kelly, J.P. (2008): Trans-species assessment of antidepressant activity in a rodent model of depression. Pharmacol Rep. 60: 404-408.

Feyissa, A.M. and Kelly J.P. (2008): A review of the neuropharmacological properties of khat Prog Neuropsychopharmacol Biol Psychiatry32: 1147-1166.

Roche, M., Kelly, J.P., O'Driscoll, M. and Finn D.P. (2008): Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats. Immunology 125: 263-71.

Lab members 
Ms. Nikita Burke 
Ms. Kate McDonnell-Dowling 
Ms. Karen Banneton 
Ms. Zara McAleavey

Contact details 
Email: john.kellynuigalway.ie 
Tel: + 353 91 493268, Ext. 3268 
Fax: + 353 91 525700 
Web:  http://www.nuigalway.ie/neuroscience