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Microbiology - EPRL    

Welcome to the NUI, Galway Enteric Pathogen Research Laboratory Homepage.

The Enteric Pathogen Research Laboratory (EPRL) was founded in 1997 where research is based on bacterial pathogens with specific focus on Campylobacter jejuni, the major causative agent of gastro-enteritis worldwide.  The areas of research of this lab are summarised below.

Areas of Research And Staff

Detection and Epidemiology

Use of Genotyping methods and DNA probe technology for detection and epidemiological studies on pathogenic bacteria.
Use of molecular methods (culture and DNA - based) for detection identification and epidemiological studies of bacterial food pathogens. Methods include: PCR, PFGE, RAPD, RFLP, Ribotyping, DNA sequencing.

Adaptive Tolerance Response in Campylobacter spp.

Physiological stress response in bacteria and the effect of processing treatments of bacterial survival, virulence and gene expression. In particular the Adaptive Tolerance Response in Campylobacter spp. Methods include the use of proteomics and microarrays.

Study of antibiotic resistance mechanisms

Evaluation of the effect of sub-inhibitory concentrations of antibiotics on the selection of single and multiple drug resistance in bacterial pathogens.
       

Biofilms

Biofilm formation.

Bioactive Ingredients from Algal Sources

Assessment of the effects of the alginate and laminaran extracts on intestinal flora.
Novel Antimicrobial tools to limit Campylobacter infection of poultry

STAFF

Click here for information on:    Staff in the Enteric Pathogen Research Laboratory.

 

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