School of Physics Seminar Programme 2012-13

Venue
The Moore Institute Seminar Room

Date & Time
11th October, 2012 @ 13:00:00

School of Physics Seminar Programme 2012-2013

Minimally invasive optical method for assessment of brain perfusion deficits

Studies on a minimally-invasive technique allowing for assessment of brain perfusion at the bedside will be described. The method is based on time-resolved near infrared spectroscopy combined with monitoring of inflow and washout of indocyanine green (ICG) into the brain after its intravenous administration. Instrumental aspects of the time-resolved optical measurements carried out with sub-nanosecond resolution will be discussed. Techniques of monitoring of circulation of ICG based on measurements of changes in absorption as well as fluorescence of the dye excited in near infrared wavelength region will be presented.

The speaker is Prof. Adam Liebert, head of the Department of Biophysical Measurements and Imaging of the Nalecz Institute of Biocybernetics and Biomedical Engineering in Warsaw, Poland. He received his Ph.D. and D.Sc. in biomedical engineering from the Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences. His main area of interest is the application of near infrared spectroscopy in tissue oxygenation assessment and development of brain perfusion evaluation methodology based on time-resolved measurement of diffusely reflected light during injection of an optical contrast agent, as well as detection of fluorescence of the exogenous dye circulating in the tissue.