Nanoscale Biophotonics Research Group

Postdoctoral researchers:

Dr. Boyan Li,  joined the group in June 2006 and is developing novel chemometric based methods of analysis for complex materials.
He previously worked on the CBAS project and was employed by Bristol-Myers Squibb as part of this unique collaboration (2006-09).  

Dr. Boyan Li (2006-present):

Boyan Li graduated in 1999 with his B.S. in Chemistry from Hunan University .  Boyan worked with Prof. Yizeng Liang ( Central South University ) and Yukihiro Ozaki ( Kwansei-Gakuin University ) doing research in chemometrics during his postgraduate study. The research involved chemometric multivariate calibration & curve resolution, classification & pattern recognition, herbal medicines & quality control, and process analytical chemistry of biosamples & polymers by using vibrational spectroscopy.  Due to the original development of multi-component spectral correlative chromatography, he was awarded a Bronze Medal in 54th World Exhibition of Innovation, Research and New Technology, 2005. His current work in Alan Ryder’s Group at the National University of Ireland, Galway concerns the analysis of biopharmaceutical materials using spectroscopic and chemometric techniques.

Selected publications:

1. Using Surface-Enhanced Raman Scattering (SERS) and Fluorescence Spectroscopy for Screening Yeast Extracts, A Complex Component of Cell Culture Media. B. Li, N.M.S. Sirimuthu, B. Ray, and A.G. Ryder,   Journal of Raman Spectroscopy, in press, (2011).
2. Fluorescence EEM Spectroscopy for Rapid Identification and Quality Evaluation of Cell Culture Media Components.  B. Li, P.W. Ryan, M. Shanahan, K.J. Leister, and A.G. Ryder. Applied Spectroscopy, 65(11), 1240-1249, (2011).
   DOI: http://dx.doi.org/10.1366/11-06383
3. Rapid Characterisation and Quality Control of Complex Cell Culture Media Solutions using Raman Spectroscopy and Chemometrics. B. Li, P.W. Ryan, B.H. Ray, K.J. Leister, N.M.S. Sirimuthu, and A.G. Ryder.  Biotechnology and Bioengineering, 107(2), 290-301, (2010).
   DOI: 10.1002/bit.22813 .
4. Prediction of Cell Culture Media performance using Fluorescence Spectroscopy.  P.W. Ryan, B. Li, M. Shanahan, K.J. Leister, and A.G. Ryder, Analytical Chemistry, 82, 1311-1317, ( 2010).
   DOI: 10.1021/ac902337c 
5. A Stainless Steel Multi-Well Plate (SS-MWP) for High Throughput Raman Analysis of Dilute Solutions. A.G. Ryder, J. de Vincentis, B. Li, P.W. Ryan, N.M.S. Sirimuthu, and K.J. Leister.   Journal of Raman Spectroscopy, 41(10), 1266-1275, (2010).
   DOI: 10.1002/jrs.2586.
6. Modified Secured Principal Component Regression for Analysis of Unexpected Chromatographic Features in Herbal Fingerprints. B. Y. Li, Y. Hu, Y. Z. Liang, P. S. Xie, Y. Ozaki. Analyst , 131, 538–546, (2006).
   
7. Quality Evaluation of Fingerprints of Herbal Medicine with Chromatographic Data. B. Y. Li, Y. Hu, Y. Z. Liang, P. S. Xie, Y. P. Du. Anal. Chim. Acta, 514, 69–77, (2004).
   
8. Spectral Correlative Chromatography and Its Application to Analysis of Chromatographic Fingerprints of Herbal Medicines. B. Y. Li, Y. Hu, Y. Z. Liang, L. F. Huang, C. J. Xu, P. S Xie. Journal of Separation Science, 27, 581–588, (2004).
   
9. Noise Perturbation in Functional Principal Component Analysis Filtering for Two-Dimensional Correlation Spectroscopy: Its Theory and Application to Infrared Spectra of a Poly(3-hydroxybutyrate) Thin Film. Y. Hu, B. Y. Li, H. Sato, I. Noda, Y. Ozaki. Journal of Physical Chemistry A , 110(39), 11279-11290, (2006).

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