National Centre for Biomedical Engineering Science (NCBES)
The National Centre for Biomedical Engineering Science at NUI, Galway, is an interdisciplinary research centre, which brings together scientists, engineers, and clinicians with a focus on innovative diagnostic and therapeutic solutions to current medical challenges such as cardiovascular disease, orthopaedics, neurodegenerative disease, and cancer.
The NCBES currently has over 400 members, including academic staff, full-time researchers and post-graduate students. Key research areas are Biomedical Engineering, Cancer, Glycosciences, Neuroscience, and Regenerative Medicine.
Biomedical EngineeringThe Biomedical Engineering research involves joint collaborative research projects focused on cardiovascular, musculo-skeletal, rehabilitation, and neural bioelectronics research. There are research clusters working in the following areas:
- Biomechanics, including cardiovascular and pulmonary biomechanics, orthopedic biomechanics and cardiovascular medical device analysis and design.
- Biomaterials and tissue engineering, including use of materials in biomedicine and the development of bioanalogous biomaterials for regenerative and clinical applications.
- Bioelectronics, including biometrics, cardiovascular electronics, diagnostic and therapeutic engineering for cancer, neural engineering, rehabilitation engineering and sports and exercise engineering
CancerThe Cancer research theme is developing a functional understanding of cancer, its cellular and molecular basis, the biology of tumours, and the translation of biological knowledge into new and effective markers and treatments. There are three main research clusters with a focus on cancer: genome stability, apoptosis and cell signalling. The NBCRI also funds qualified research scientists and clinicians to carry out research into breast cancer.
NeuroscienceThe Neuroscience theme incorporates research on behavioural and whole systems neuroscience, understanding neurodegeneration, neuroprotection, regeneration of the nervous system, and applied clinical neuroscience. The Neuroscience cluster has three research subgroups; the Applied Clinical Neurosciences subgroup brings together clinical and basic scientists in a forum to encourage collaborative interdisciplinary research; the Integrative Neurosciences subgroup is a focus for behavioural and whole systems neuroscience; while the Regenerative Neurobiology subgroup focuses on understanding neurodegeneration, neuroprotection and regeneration of the nervous system.
This research is relevant to disease states including spinal cord injury, anxiety, schizophrenia as well as neurodegenerative disorders such as Parkinson's disease and multiple sclerosis.
Regenerative MedicineThe Regenerative Medicine research theme combines the technologies of gene therapy and adult stem cell therapy with the aim of regeneration and repair of tissues. The unique feature of this research is the novel integration of both therapies in a complementary research and development programme. It includes translational research programmes in cardiovascular disease, orthopaedics and rheumatology, neuro-ophthalmology, gastrointestinal disease and respiratory
Microscopy facilities include Confocal Microscopes, a Scanning Electron Microscope with EDX, a Transmission Electron Microscope and a Scanning Probe / Atomic Force Microscope.
The Biomechanics range of equipment includes Axial / Torsion Servo hydraulic Testing System, Mechanical Thermal Analyser, Fatigue and Impact tester and Rapid Prototyping System.
The Centre has fully equipped cell culture suites in addition to molecular biology and functional genomics suites. Uniquely, the NCBES incorporates the National Gene Vector Laboratory which facilitates the manufacture of clinical grade gene and cell products.