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About NUI Galway
About NUI Galway
Since 1845, NUI Galway has been sharing the highest quality teaching and research with Ireland and the world. Find out what makes our University so special – from our distinguished history to the latest news and campus developments.
Colleges & Schools
Colleges & Schools
NUI Galway has earned international recognition as a research-led university with a commitment to top quality teaching across a rang of key areas of expertise.
Business & Industry
Guiding Breakthrough Research at NUI Galway
We explore and facilitate commercial opportunities for the research community at NUI Galway, as well as facilitating industry partnership.
- Alumni, Friends & Supporters
At NUI Galway, we believe that the best learning takes place when you apply what you learn in a real world context. That's why many of our courses include work placements or community projects.
Dr. Howard Oliver Fearnhead PhD
|In 1991 Dr Fearnhead completed a BSc. in Pharmacology and Toxicology at the London School of Pharmacy, before completing a PhD. in apoptosis at the MRC-Toxicology Centre, Leicester, UK in 1995. In 1999 Dr Fearnhead completed a post-doctoral fellowship at Cold Spring Harbor Laboratory, NY before moving to the National Cancer Institute in Maryland as a tenure track principle investigator. In 2004 Dr Fearnhead moved to the National Centre of Biomedical Engineering Science (NCBES), National University of Ireland, Galway (http://www.nuigalway.ie/ncbes) and in 2006 was appointed a lecturer in Pharmacology and Therapeutics (http://www.nuigalway.ie/pharmacology).|
Peer Reviewed Journals
|Ormerod, M. G., Sun, X. M., Snowden, R. T., Davies, R., Fearnhead, H. O. & Cohen, G. M. (1993) 'Increased membrane permeability of apoptotic thymocytes: a flow cytometric study'. Cytometry, 14 :595-602. [Details]|
|Fearnhead, H. O., Chwalinski, M., Snowden, R. T., Ormerod, M. G. & Cohen, G. M. (1994) 'Dexamethasone and etoposide induce apoptosis in rat thymocytes from different phases of the cell cycle'. Biochemical Pharmacology, 48 :1073-1079. [Details]|
|Cohen G. M., X.M.Sun, X. M., Fearnhead, H. O., MacFarlane, M., Brown, D. G., Snowden, R. T. & Dinsdale, D. (1994) 'Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes'. Journal of Immunology, 153 :507-516. [Details]|
|Cohen, G. M., MacFarlane, M., Fearnhead, H. O., Sun, X. M. and Dinsdale, D. (1995) 'Mechanisms of Cell Death, with Particular Reference to Apoptosis'. Molecular and Cellular Mechanisms of Toxicity, . [Details]|
|Fearnhead, H. O., McCurrach, M. E., O'Neill, J., Zhang, K., Lowe, S. W. and Lazebnik, Y. A. (1997) 'Oncogene-dependent apoptosis in extracts from drug-resistant cells'. Genes and Development, 11 :1266-1276. [Details]|
|Fearnhead, H. O., Rodriguez, J., Govek, E., Guo, W., Kobayashi, R., Hannon, G. and Lazebnik, Y. A. (1998) 'Oncogene-dependent caspase activation is mediated by caspase-9'. Proceedings of the National Academy of Sciences, 95 :13664-13669. [Details]|
|Fearnhead, H. O. (2001) 'Cell-free systems to study apoptosis'. Methods in Cell Biology, 66 :167-185. [Details]|
|Fearnhead, H. O. (2004) 'Getting Back on Track, or What to Do When Apoptosis Is De-Railed: Recoupling Oncogenes to the Apoptotic Machinery'. Cancer Biology & Therapy, 3 (1):21-28. [Details]|
|Chandra, D., Bratton, S. B., Person, M. D., Tian, Y., Martin, A. G., Ayres, M., Fearnhead, H. O., Gandhi, V. and Tang, D. G. (2006) 'Intracellular Nucleotides Act as Critical Prosurvival Factors by Binding to Cytochrome C and Inhibiting Apoptosome'. Cell, 125 :1333-1346. [Details]|
|Fearnhead (2004) Oncogene dependent caspase activation. MRC Toxicology Unit, University of Leicester. Invited papers [Details]|
|Fearnhead, H (2005) Oncogene dependent caspase activation. NA Rockville, Maryland, USA. Invited papers [Details]|
|Fearnhead, H (2005) Oncogene dependent caspase activation. Univeristy of Texas, Austin. Invited papers [Details]|