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Prof Matthew Griffin MB, BCh, BAO, MRCPI, MRCP
Contact Details
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Biography:
| My primary qualification is in Medicine. My training took me from Cork and Dublin to the Mayo Clinic in Minnesota, USA where I specialised in the care of patients with kidney disease and organ transplants. My interest in transplantation resulted in a research fellowship in basic immunology at the University of Chicago, USA following which I spent 9 years combining clinical transplant medicine with laboratory-based immunology research at Mayo Clinic. During that time I received funding for a variety of clinical and basic projects from Mayo Clinic, NIH, the National Kidney Foundation, Roche Organ Transplant Research Foundation, Wyeth Pharmaceuticals and Abbott Laboratories. I developed specific interest in the immune-modulating properties of Vitamin D, the molecular basis for chronic kidney transplant rejection, complications of organ transplantation and the involvement of cells from the immune system in kidney disease. These projects eventually resulted in over 80 publications. In 2008 I had the opportunity to return to Ireland to take up the post of Professor of Transplant Biology affiliated with the Regenerative Medicine Institute (REMEDI) at NUI Galway. My laboratory group has received funding from SFI to study the immunologic basis of acute and chronic kidney disease and how this might be altered by stem cell-based therapy. With other REMEDI researchers we are specifically studying the immune therapeutic properties of mesenchymal stem cells (MSC). In the future, our goal is to translate new insights in basic immunology into diagnostic tools and treatment strategies for kidney disease, transplant loss and other immune-mediated diseases. |
Peer Reviewed Journals
| Griffin MD, V Gamble , DS Milliner , MR Gomez , PC Harris , VE Torres (1993) 'Reversible hypocalciuria with marginal hypercalcaemia in renal magnesium wasting'. Quarterly J Med, 86 :127-134. [Details] |
| Griffin MD, JP Grande, RH Wiesner, JA Velosa (1995) 'Renal papillary necrosis: A sixteen year clinical experience'. J Am Soc Nephrol, 6 :248-256. [Details] |
| Khattri R, JA Auger, MD Griffin, AH Sharpe, and JA Bluestone (1996) 'Vascular expression of polycystin'. J Am Soc Nephrol, 8 :616-626. [Details] |
| Lee K-M, E Chuang E , MD Griffin , R Khattri, DK Hong, W Zhang , L Samelson , D Strauss, LE Samelson, C Thompson , and JA Bluestone (1996) 'Immunolocalization of polycystin in the kidney and liver of patients with autosomal dominant polycystic kidney disease'. Proc Assoc Am Physicians, 108 :185-197. [Details] |
| Griffin MD, PO Holman , DK Hong, K-M Lee, MJ Whitters, M Collins, DM Kranz, and JA Bluestone (1997) 'Expression of polycystin in mouse metanephros and extra-metanephric tissues'. Kidney Int, 52 :1196-1205. [Details] |
| Stegall, MD, DY Kim, M Prieto, AJ Cohen, MD Griffin, TR Schwab, SL Nyberg, JA Velosa, JM Gloor, F Innocenti, H Bohorquez, PG Dean, HA Carpenter, S Sterioff, and TS Larson. (1997) 'Diffuse proliferative glomerulonephritis and acute renal failure associated with Staphylococcal osteomyelitis'. J Am Soc Nephrol, 8 :1633-1639. [Details] |
| Velosa, JA, Griffin, MD, Larson, TS, Gloor, JM, Schwab, TR, Sterioff, S, Bergstralh, EJ, and Stegall, MD. (1997) 'Neonatal presentation of polycystic kidney disease with a maternal history of tuberous sclerosis'. Nephrol Dial Transplant, 12 :2284-2288. [Details] |
| Griffin MD, PO Holman, Q Tang, N Ashourian, U Korthäuer , DM Kranz, and JA Bluestone (1998) 'Lymphoproliferative disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of TH2 responses'. J Immunol, 162 :5784-5791. [Details] |
| Gloor, J, Cohen, AJ, Lager, D, Grande, J, Velosa, J, Larson, TS, Schwab, T, Griffin, MD, Prieto, M, Nyberg, S, Sterioff, S, and Stegall, MD. (1998) 'Prolonged anuria complicating primary sclerosing cholangitis - successful outcome following orthotopic liver transplantation'. Am J Kidney Dis, 31 :360-363. [Details] |
| Griffin MD, WH Lutz, V Phan, LA Bachman, DJ McKean, and R Kumar (1998) 'Molecular basis of T cell inactivation by CTLA-4'. Science, 282 :2263-2266. [Details] |
| Griffin, MD, VA Phan, WH Lutz, LA Bachman, DJ McKean, and R Kumar (2000) 'Potent inhibition of dendritic cells differentiation and maturation by vitamin D analogs'. Biochem Biophys Res Comm, 270 :701-708. [Details] |
| * Ugurlu, MM, MD Griffin, T O'Brien, HD Tazelaar, VM Miller, and CM McGregor (2000) 'Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152)'. J Immunol, 164 :4433-4443. [Details] |
| * Kanaan, N, LA Bachman, CGA McGregor, and Griffin, MD (2001) 'Dendritic Cell Modulation by 1 ,25 dihydroxyvitamin D3 and its Analogs: A VDR-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo'. Proc Natl Acad Sci USA, 98 :6800-6805. [Details] |
| * Xing, N, Maldonado, ML, Bachman LA, McKean, DJ, Kumar, R, and Griffin, MD. (2001) 'Development and Applications of Surface-linked Single Chain Antibodies against T Cell Antigens'. J Immunol Methods, 248 :77-90. [Details] |
| Stegall MD, Larson TS, Prieto M, Gloor J, Textor S, Nyberg S, Sterioff S, Ishitani M, Griffin M, Schwab T, Talor S, Cosio F, Kudva Y, Dicke-Henslin D, Kreps M, Fix L, Bauer C, Murphy M, Kosberg K, Tarara D, Velosa J. (2001) 'Thymoglobulin induction decreases rejection in solitary pancreas transplantation'. Transplantation, 72 :1671-1675. [Details] |
| Griffin MD and Kumar. (2001) 'The effects of CTLA-4Ig on acute lung allograft rejection - a comparison of intrabronchial gene therapy with systemic administration of protein'. Transplantation, 71 :1867-1871. [Details] |
| Gloor JM, Lager DJ, Moore SB, Pineda AA, Fidler ME, Larson TS, Grande JP, Schwab TR, Griffin MD, Prieto M, Nyberg SL, Velosa JA, Textor SC, Platt JL, Stegall MD. (2002) 'Can a living donor kidney function equivalently to its native partner?'. Am. J. Transplantation, 2 :252-259. [Details] |
| * Buehrig, CK, Lager DJ, Stegall MD, Kreps MA, Kremers WK, Gloor JM, Schwab TR, Velosa JA, Fidler ME, Larson TS, Griffin MD. (2002) 'Subclinical rejection in renal allografts: A comparison of tacrolimus and cyclosporine'. Transplantation, 73 :1965-1968. [Details] |
| Stegall MD, Larson TS, Prieto M, Gloor J, Textor S, Nyberg S, Sterioff S, Ishitani M, Griffin M, Kremers W, Lund W, Schwab T, Cosio F, Velosa J. (2002) 'Living-donor kidney transplantation at Mayo Clinic, Rochester'. Clin Transpl, :155-161. [Details] |
| * Hogan MC, Griffin MD, Rossetti S, Torres VE, Ward CJ, Harris PC (2002) 'Distinctive dendritic cell modulation by vitamin D3 and glucocorticoid pathways'. Biochem Biophys Res Comm, 297 :645-653. [Details] |
| Griffin MD, Xing N, Kumar R. (2003) 'Generation of antigen-specific, interleukin-10-producing T-cells using dendritic cell stimulation and steroid hormone conditioning'. Transplant Immunol, 11 :323-333. [Details] |
| Pittock ST, Norby SM, Grande JP, Croatt AJ, Bren GD, Badley AD, Caplice NM, Griffin MD, Nath KA. (2003) 'Regulation of RelB in dendritic cells by 1 ,25 dihydroxyvitamin D3 and its analogs'. J. Biol. Chem, 278 :49378-49385. [Details] |
| * Ugurlu, M, Griffin, MD, Tazelaar, HD, McGregor, CG (2003) 'Effects of 1 ,25(OH)2D3 and its analogs on dendritic cell function'. J Cell Biochem, 88 :323-326. [Details] |
| Textor SC, Taler SJ, Larson TS, Prieto M, Griffin MD, Gloor J, Nyberg S, Velosa J, Schwab T, Stegall M. (2003) 'ABO-incompatible kidney transplantation using both A2 and non-A2 living donors'. Transplantation, 75 :971-977. [Details] |
| * Mazur MJ, Rea DJ, Griffin MD, Larson TS, Prieto M, Gloor JM, Schwab TS, Textor SC, Nyberg SL, Stegall MD. (2003) 'Blood pressure evaluation among older living kidney donors'. J. Am. Soc. Nephrol, 14 :2159-2167. [Details] |
| Fidler ME, Gloor JM, Lager DJ, Larson TS, Griffin MD, Textor SC, Schwab TR, Prieto M, Nyberg SL, Ishitani MB, Grande JP, Kay PA, Stegall MD. (2003) 'Kidney transplantation without calcineurin inhibitors using sirolimus'. Transplant Proc, 35 (3):125s-127s. [Details] |
| Larson TS, Bohorquez H, Rea DJ, Nyberg SL, Prieto M, Sterioff S, Textor SC, Schwab TR, Griffin MD, Gloor JM, Kudva YC, Kremers WK, Stegall MD. (2003) 'Overcoming a positive crossmatch in living-donor kidney transplantation'. Am. J. Transplant, 3 :1017-1023. [Details] |
| * Diaz Encarnacion MM, Griffin MD, Slezak JM, Bergstralh EJ, Stegall MD, Velosa JA, Grande JP. (2003) 'Synergistic effects of CTLA-4Ig and sirolimus on orthotopic lung allograft survival and histology'. Transplantation, 76 :489-495. [Details] |
| * Dong X, Bachman LA, Kumar R, Griffin MD (2003) 'Porcine dendritic cells promote xenogeneic B lymphocyte proliferation and survival by contact-independent and contact-dependent mechanisms'. Am J Transplant, 3 :403-415. [Details] |
| * Dong X, Craig TA, Xing N, Bachman LA, Paya CV, Weih F, McKean DJ, Kumar R, Grifin MD. (2003) 'PKHDL1, a homolog of the autosomal recessive polycystic kidney disease gene, encodes a receptor with inducible T lymphocyte expression'. Hum Mol Genetics, 12 :685-698. [Details] |
| Gloor JM, DeGoey SR, Pineda AA, Moore SB, Prieto M, Nyberg SL, Larson TS, Griffin MD, Textor SC, Velosa JA, Schwab TR, Fix LA, Stegall MD. (2003) 'The influence of surveillance renal allograft biopsy on diagnosis and prognosis of polyomavirus-associated nephropathy'. Kidney Int, 64 :665-673. [Details] |
| Cosio FG, Grande JP, Larson TS, Gloor JM, Velosa JA, Hesley GK, Textor SC, Griffin MD, Stegall MD. (2004) 'Pancreas-after-kidney transplantation: an increasingly attractive alternative to simultaneous pancreas-kidney transplantation'. Transplantation, 77 :838-843. [Details] |
| * Dong X, * Swaminathan S, Bachman LA, Croatt AJ, Nath KA, Griffin MD. (2004) 'Correlation of quantitative digital image analysis with glomerular filtration rate in chronic allograft nephropathy'. Am. J. Transplant, 4 :248-256. [Details] |
| Textor SC, Taler SJ, Driscoll N, Larson TS, Gloor J, Griffin M, Cosio FG, Schwab T, Prieto M, Nyberg S, Ishitani M, Stegall M. (2004) 'Decline in native renal function early after bladder-drained pancreas transplant alone'. Transplantation, 77 :844-849. [Details] |
| Cosio FG, Kudva Y, van de Velde M, Larson, TS, Textor SC, Griffin MD, Stegall MD. (2004) 'Patient and graft outcomes form older living donors are similar to those from younger donors despite lower levels of GFR'. Kidney International, 66 :1654-1661. [Details] |
| Leung N, Griffin MD, Dispenzieri A, Haugen EN, Gloor JM, Schwab TR, Textor SC, Lacy MQ, Litzow MR, Cosio FG, Larson TS, Gertz MA, Stegall MD. (2004) 'Blood pressure and renal function after kidney donation in hypertensive living donors'. Transplantation, 78 :276-282. [Details] |
| * Pena de la Vega LS, Torres A, Bohorquez HE, Heimbach JK, Gloor JM, Schwab TR, Taler SJ, Nyberg SL, Ishitani MB, Prieto M, Velosa JA, Larson, TS, Stegall MD, Cosio FG, Textor SC, Griffin MD. (2004) 'Histologic Findings of Antibody-Mediated Rejection in ABO Blood-Group-Incompatible Living-Donor Kidney Transplantation'. Am. J. Transplant, 4 :101-107. [Details] |
| Sommer SL, Berndt TJ, Patel JB, Dong X, Griffin MD, Grande JP, van Duersen JMA, Sieck GM, Redfield MM, Romero JC, Kumar R. (2004) 'Gene expression profiles in dendritic cells conditioned by 1 ,25-dihydroxyvitamin D3 analog'. J. Steroid. Biochem. Mol. Biol, 89-90:443-448, . [Details] |
| * Dong X, Lutz W, Schroeder TM, Bachman LA, Westendorf JJ, Kumar R, Griffin MD (2005) 'MCP-1 is upregulated in unstressed and stressed HO-1 knockout mice: pathophysiologic correlates'. Kidney Int, 68 :611-622. [Details] |
| Graham DB, Bell MP, Huntoon CJ, Griffin MD, Tai XG, Singer A, McKean DJ. (2005) 'Regulation of relB in dendritic cells via modulated association of vitamin D receptor and histone deacetylase 3 with the promoter'. Proc Natl Acad Sci USA, 102 :16007-16012. [Details] |
| Nguyen M, d'Alésio a, Pascussi JM, Kumar R, Griffin MD, Dong X, Guillozo H, Rizk-Rabin M, Sinding C, Bougnères P, Jehan F, Garabedian M (2005) 'Antigen presentation by dendritic cells in the renal lymph nodes is linked with systemic and local injury to the kidney'. Kidney Int, 68 :1096-1108. [Details] |
| Cosio FG, Grande JP, Wadeo H, Larson TS, Griffin MD, Stegall MD. (2005) 'New onset hyperglycemia and diabetes are associated with increased cardiovascular risk after kidney transplantation'. Kidney Int, 67 :2415-2421. [Details] |
| Larson TS, Dean PG, Stegall MD, Griffin MD, Textor SC, Schwab TR, Gloor JM, Cosio FG, Lund WJ, Kremers WK, Nyberg SL, Ishitani MB, Prieto M, Velosa JA. (2005) 'Living Donor Kidney and Autologous Stem Cell Transplantation for Primary Systemic Amyloidosis (AL) with Predominant Renal Involvement'. Am J Transplant (Accompanying Editorial, Am J Transplant, 5:1585-1586), 5 :1660-1670. [Details] |
| *Swaminathan S, Lager DJ, Qian X, Stegall MD, Larson TS, Griffin MD. (2005) 'Predicting subsequent decline in kidney allograft function from early surveillance biopsies'. Am J Transplant, 5 :2464-2472. [Details] |
| Kipp BR, Sebo TJ, Griffin MD, Ihrke JM, Halling KC. (2005) 'Kidney allograft fibrosis and atrophy after living donor transplantation'. Am J Transplant, 5 :1130-1136. [Details] |
| * Wadei HM, Rule AD, Lewin M, Mahale AS, Khamash HA, Schwab TR, Gloor JM, Textor SC, Fidler ME, Lager DJ, Larson TS, Stegall MD, Cosio FG, Griffin MD. (2005) 'Analysis of polyomavirus-infected renal transplant recipients' urine specimens - Correlation of routine urine cytology, fluorescence in situ hybridization, and digital image analysis'. Am J Clin Pathol, 124 :854-861. [Details] |
| Fife BT, Griffin MD, Abbas AK, Locksley RM, Bluestone JA. (2005) 'Elevated blood pressure and cardiac hypertrophy following ablation of the Gly96/IEX-1 gene'. J. Applied Physiol, 124 :854-861. [Details] |
| Cosio FG, Amer H, Grande JP, Morales P, Larson, TS, Stegall MD, Griffin MD. (2006) 'Kidney transplant function and histological clearance of virus following diagnosis of polyomavirus-associated nephropathy (PVAN)'. Am J Transplant, 6 :1025-1032. [Details] |
| Gera M, Griffin MD, Specks U, Leung N, Stegall MD, Fervenza FC. (2006) 'Collapsing and non-collapsing focal segmental glomerulosclerosis in kidney transplants'. Nephrol Dial Transplant, 21 :2607-2614. [Details] |
| Park WD, Griffin MD, Grande JP, Cosio FG, Stegall MD. (2006) 'Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist'. J Clin Invest(Commentary by Javeed Ansari M and Sayegh MH, J Clin Invest, 2006, 116: 2080-2083), 116 :2252-2261. [Details] |
| Wadei HM, Amer H, Taler SJ, Cosio FG, Griffin MD, Grande JP, Larson TS, Schwab TR, Stegall MD, Textor SC. (2006) 'Nephrogenic fibrosing dermopathy is linked to high dose erythropoietin therapy'. Ann Int Med, 145 :234-235. [Details] |
| * Swaminathan S, Ahmed I, McCarthy JT, Albright RC, Pittelkow MR, Caplice NM, Griffin MD, Leung N. (2006) 'Complete Avoidance of Calcineurin Inhibitors in Renal Transplantation: A Randomized Trial Comparing Sirolimus and Tacrolimus'. Am J Transplant(Accompanying Editorial, Am J Transplant, 6:445-446), 6 :514-522. [Details] |
| Griffin MD, Dong X, Kumar R. (2006) 'CD28 ligation costimulates cell death but not maturation of double-positive thymocytes due to defective ERK MAPK signaling'. J Immunol, 177 :6098-6107. [Details] |
| * Dong X, * Swaminathan S, Bachman LA, Croatt AJ, Nath KA, Griffin MD. (2006) 'Vitamin D resistant rickets and type 1 diabetes in a child with compound heterozygous mutations of the vitamin D receptor: dissociated responses of the CYP-24 and relB promoters to 1,25-dihydroxyvitamin D3'. J Bone Min Res, 21 :886-894. [Details] |
| Cosio FG, Hickson LJ, Griffin MD, Stegall MD, Kudva YG. (2007) 'Polyomavirus PCR as a surrogate marker of polyomavirus-associated nephropathy'. Transplantation, 84 :340-345. [Details] |
| Tracz MJ, Juncos JP, Croatt AJ, Ackerman AW, Grande JP, Knutson KL, Kane GC, Terzic A, Griffin MD, Nath KA. (2007) 'Molecular evidence of injury and inflammation in normal and fibrotic renal allografts one year post-transplant'. Transplantation, 83 :1466-1476. [Details] |
| Griffin MD and TS Larson. (2007) 'Deficiency of HO-1 impairs renal hemodynamics and exaggerates systemic inflammatory responses to renal ischemia'. Kidney Int, 72 :1073-1080. [Details] |
| * Khamash HA, Wadei HM, Mahale AS, Larson TS, Stegall MD, Cosio FG, Griffin MD. (2007) 'Comparison of low versus high tacrolimus levels in kidney transplantation: assessment of efficacy by protocol biopsies'. Transplantation, 83 :411-416. [Details] |
| Dean PG, Grande JP, Sethi S, Park WD, Griffin MD, Cosio FG, Larson TS, Stegall MD. (2007) 'Transplant glomerulopathy: subclinical incidence and association with alloantibody'. Am J Transplant, 9 :2124-2132. [Details] |
| Griffin MD and Prieto M. (2007) 'Reduction of immunosuppression for transplant-associated skin cancer: thresholds and risks'. Br J Dermatol, 157 :1183-1188. [Details] |
| Griffin MD and FP Muldowney. (2007) 'Renal hemodynamics, systemic and apoptotic responses to lipopolysaccharide in HO-1-/- mice'. Am J Pathol, 170 :1820-1839. [Details] |
| Viscount HB, Eid AJ, Espy MJ, Griffin MD, Thomsen KM, Harmsen WS, Razonable RR, Smith TF. (2007) 'Recurrence of ANCA-associated Vasculitis Following Kidney Transplantation in the Modern Era of Immunosuppression'. Kidney Int, 71 :1296-1301. [Details] |
| Otley CC, Griffin MD, Charlton MR, Edwards BS, Neuburg M, Stasko T. (2007) 'Influence of Recipient Age and Donor Gender on Polyomavirus-associated Nephropathy Risk in Recent Kidney Transplants'. Kidney Int, 71 :1302-1309. [Details] |
| Gloor JM, Sethi S, Stegall MD, Park WD, Moore SB, DeGoey S, Griffin MD, Larson TS, Cosio FG. (2007) 'Diurnal blood pressure changes one year after kidney transplantation: Relationship to allograft function, histology, and resistive index'. J Am Soc Nephrol, 18 :1607-1615. [Details] |
| Dong X, Bachman LA, Miller MN, Nath KA, Griffin MD. (2007) 'Vitamin D receptor-mediated suppression of RelB in antigen presenting cells: A paradigm for ligand-augmented negative transcriptional regulation'. Arch Biochem Biophys, 460 :218-226. [Details] |
| Tracz MJ, Juncos JP, Grande JP, Croatt AJ, Ackerman AW, Rajagopalan G, Knutson KL, Badley AD, Griffin MD, Alam J, Nath KA. (2007) 'Resident dendritic cells are the predominant TNF-secreting cell in early renal ischemia-reperfusion injury'. Kidney Int(Commentary by Nelson PJ, Kidney Int. 604-605.), 71 :619-628. [Details] |
| Hickson LJ, Gera M, Amer H, Iqbal CW, Moore TB, Milliner DS, Cosio FG, Larson TS, Stegall MD, Ishitani MB, Gloor JM, Griffin MD. (2008) 'Pulmonary hypertension is associated with reduced patient survival after kidney transplantation'. Transplantation, 86 :1384-1388. [Details] |
| Leung N, Gloor JM, Dean PG, Lacy MQ, Porrata LF, Griffin MD. (2008) 'Case studies in transplant ethics'. Transplantation Reviews, 22 :178-183. [Details] |
| Hickson LJ, Cosio FG, El-Zoghby Z, Gloor JM, Stegall MD, Griffin MD, Jaffe AS. S (2008) 'Kidney transplant histology following one year of continuous therapy with sirolimus compared to tacrolimus'. Transplantation, 85 :1212-1215. [Details] |
| Griffin MD, J Björnssen, SB Erickson (2008) 'A role for dendritic cells in the inflammatory response and influx of IL-17 T-cells following acute renal obstruction'. Kidney Int, 74 :1294-1309. [DOI] [Details] |
| Issa N, Krowka MJ, Griffin MD, Hickson LJ, Stegall MD, Cosio FG. (2008) 'Patient survival and cardiovascular risk after kidney transplantation: The challenge of diabetes'. Am J Transplant, 8 :593-599. [Details] |
| Griffin MD, Ritter T, Mahon BP. (2010) 'Immunological Aspects of Allogeneic Mesenchymal Stem Cell Therapies'. Hum Gene Ther Impact Factor 4.2, . [Details] |
| Griffin, M., Greiser, U., Barry, F., O'Brien, T., & Ritter, T. (2010) 'Genetically Modified Mesenchymal Stem'. Discovery Medicine, 9 (46):219-223. [ARAN Link] [Details] |
| Pindjakova J, Griffin MD. Horseman, 'Accepted: Pass By! Defective Neutrophil Rolling and Transmigration in Acute Uremia'. Kidney Int. Impact Factor 6.2, . [Details] |
| Duffy MM, Ritter T, Ceredig R, Griffin MD. 'Accepted: Mesenchymal Stem Cell Effects on T-cell Effector Pathways'. Stem Cell Res Ther, . [Details] |
Conference Poster
| Griffin MD, Lutz W, Bachmann L, McKean D, and Kumar R (2000) Dendritic cell differentiation, maturation, and function are directly modulated by activated vitamin D and its analogues. Poster presentation at the 16th International Congress of the Transplantation Society. Conference Poster [Details] |
| Griffin MD, Lutz W, Phan V, Bachman LA, McKean D, and Kumar R. (2001) Role for the 1a,25 dihydroxyvitaminD3/VDR pathway in regulating dendritic cell maturation in vivo. Poster presentation at Keystone Symposium, D4. Conference Poster [Details] |
| Griffin MD, Lutz W, Phan V, Bachman LA, McKean D, and Kumar R. (2001) Dendritic cells conditioned by a Vitamin D analog are resistant to maturational stimuli even after analog withdrawal. Poster presentation at the American Society of Transplantation Annual Meeting, Chicago, IL. Conference Poster [Details] |
| Griffin MD, Lutz W, Phan VA, Bachman LA, McKean DJ, and Kumar R. (2001) Dendritic cell modulation by 1a,25-Dihydroxyvitamin D3 and its analogs: A vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo. Poster presentation at the American Society of Nephrology Annual Meeting. Conference Poster [Details] |
| Xing, N, LA Bachman, DJ McKean, R Kumar, and MD Griffin. (2002) Vitamin D and glucocorticoid pathways preferentially inhibit cognate and innate dendritic cell functions. Poster presentation at the American Transplant Congress, Washington, DC. Conference Poster [Details] |
| Buehrig C, Kreps M, Schwab T, Gloor J, Velosa J, Larson T, Lager D, Fidler M, Stegall M, Kremers W, and Griffin MD. (2002) Protocol biopsy - earlier diagnosis and improved prognosis in BK nephropathy. Poster presentation at the 19th International Congress of the Transplantation Society Transplant Congress, Miami, FL. Conference Poster [Details] |
| Griffin MD, and Bachman LA. (2002) Renal dendritic cells: Phenotypic and functional characteristics. Poster presentation at the Seventh International Symposium on Dendritic Cells, Bamburg, Germany. Conference Poster [Details] |
| Griffin MD, Lutz W, Phan VA, Bachman LA, McKean DJ, and Kumar R. (2002) xNature's Anti-adjuvants: Vitamin D and glucocorticoid modulate dendritic cell functions in separate and overlapping patterns. Poster presentation at Keystone Meeting D1. Conference Poster [Details] |
| Buehrig CK, Hamad A, Kreps MA, Lager DJ, Fidler ME, Gloor JM, Schwab TR, Griffin MD. (2003) Graft outcomes in polyomavirus-associated nephropathy - the influence of surveillance biopsy and conversion to cyclosporine. Poster presentation at American Transplant Congress, Washington DC. Conference Poster [Details] |
| Griffin MD, Slezak JM, Kozel TK, Bergstralh EJ, Schwab TR, Gloor JM, Stegall MD, Larson TS, Grande JP, Velosa JA. (2003) Renal function loss in chronic allograft nephropathy: results of a two-year study of mycophenolate mofetil substitution for azathioprine. Poster presentation at American Transplant Congress. Washington DC: Conference Poster [Details] |
| Dong X, Bachman LA, Griffin MD. (2003) Dendritic cell turnover, antigen uptake, and trafficking in the kidney and its draining lymph tissue. 2003. Poster presentation at 2003 American Society of Nephrology annual meeting. San Diego, Ca: Conference Poster [Details] |
| Dong X, Craig T, Xing N, Bachman LA, Weih F, Paya CV, McKean DJ, Kumar R, Griffin MD. (2003) physiologic and therapeutic implications for dendritic cell function. Poster presentation at the 12th Workshop on Vitamin D Maastricht. The Netherlands: Conference Poster [Details] |
| Pena de la Vega L, Torres A, Bohorquez H, Gloor JM, Schwab TR, Velosa JA, Larson TS, Stegall MD, Textor SC, Griffin MD. (2003) Is older donor age associated with adverse graft outcomes in living donor kidney transplantation?. Poster presentation at American Transplant Congress. Washington DC: Conference Poster [Details] |
| Pena de la Vega L, Torres A, Bohorquez H, Gloor JM, Schwab TR, Velosa JA, Larson TS, Stegall MD, Textor SC, Griffin MD. (2003) Older donor age is associated with excellent graft outcomes in living donor kidney transplantation. Poster presentation at the World Congress of Nephrology. Berlin, Germany: Conference Poster [Details] |
| Dong X, Craig TA, Bachman LA, McKean DJ, Kumar R, Griffin MD. (2003) Direct transcriptional regulatoin of RelB by 1a,25-dihydroxyvitamin D3 and its analogs: physiologic and therapeutic implications for dendritic cell function. Poster presentation at 2003 American Society of Nephrology annual meeting, . San Diego, Ca: Conference Poster [Details] |
| Mahale AS, Khamash HA, Buehrig CK, Espy M, Schwab TR, Gloor JM, Lager DJ, Fidler ME, Cosio FG, Patel R, Stegall MD, Larson TS, Griffin MD. (2004) Limited benefits from cidofovir therapy combined with reduced immunosuppression in clinically-evident BK nephropathy in renal transplants. Poster presentation at the 2004 American Transplant Congress. Boston, MA: Conference Poster [Details] |
| Gregoire JR, Diaz Encarnacion M, Grande JP, Larson TS, Textor SC, Stegall MD, Griffin MD. (2004) Donor age, but not blood pressure, determines renal vessel morphometry on time-zero biopsies in an expanded living kidney donor pool. Poster presentation, American Society of Nephrology Renal Week St. Louis, MO: Conference Poster [Details] |
| Swaminathan S, Lager DJ, Lloyd RV, Larson TS, Stegall MD, Griffin MD. (2005) Clinical and histological comparison of collapsing and non-collapsing focal segmental glomerulosclerosis in kidney transplants. Poster presentation at American Tranplant Congress. Seattle, WA: Conference Poster [Details] |
| Dong X, Bachman LA, Kumar R, Griffin MD. (2005) Suppression of RelB in dendritic cells by vitamin D analogs is mediated by histone deacetylase 3. Poster presentation at American Transplant Congress. Seattle, WA: Conference Poster [Details] |
| Casey ET, Khamash HA, Hartman RP, Cosio FG, Larson TS, Stegall MD, Griffin MD. (2005) Functional and histological correlates of arcuate artery resistive indices in kidney transplants at the time of surveillance biopsy. Poster presentation at American Transplant Congress. Seattle, WA: Conference Poster [Details] |
| Dong X, Bachman LA, Kumar R, Griffin MD. (2005) Chromatin re-modeling underlies vitamin D receptor-mediated suppression of the NF-kB component Rel-B in dendritic cells. Poster presentation, ASN Renal Week. Conference Poster [Details] |
| Wadei HM, Larson TS, Kudva YC, Ramos EJ, Stegall MD, Griffin MD. (2005) Effect of the route of exocrine drainage on GFR loss in the 1st year following solitary pancreas transplant (SPT). Poster presentation, ASN Renal Week. Conference Poster [Details] |
| Swaminathan S, Dong X, Bachman LA, Croatt AJ, Nath KA, Griffin, MD. (2005) Dendritic cell phenotype and dynamics in the renal interstitium and renal lymph nodes. Poster presentation at Keystone meeting B4. Vancouver B.C: Conference Poster [Details] |
| Casey ET, Khamash HA, Casey KK, Hartman RP, Cosio FG, Larson TS, Stegall MD, Griffin MD. (2005) Arcuate artery resistive indices correlate with inflammation in kidney transplants at the time of surveillance biopsy. Poster presentation, ASN Renal Week. Conference Poster [Details] |
| Swaminathan S, Dong X, Bachman LA, Croatt AJ, Nath KA, Griffin MD. (2005) Resident dendritic cells are the predominant early source of proinflammatory products following diverse forms of acute renal injury. Poster presentation, ASN Renal Week. Conference Poster [Details] |
| Gera M, Stegall MD, Larson TS, Smith TF, Sebo TS, Griffin MD. (2006) Late sub-clinical BK polyoma virus (BKV) reactivation in kidney transplant (TX) patients. Poster presentation, National Kidney Foundation Spring Clinical Meeting. Conference Poster [Details] |
| Gera M, Gloor JM, Larson TS, Stegall MD, Griffin MD. (2006) Outcome and utility of pre- and post-kidney transplant (KTx) plasmapheresis (PP) in recurrent primary focal segmental glomerulosclerosis. Poster Presentation, ASN Renal Week. San Diego, CA: Conference Poster [Details] |
| Griffin MD, Khamash HA, Larson TS, Stegall MD, Cosio FG. (2006) Influence of recipient age and donor gender on polyomavirus-associated nephropathy rate in recent kidney transplant recipients. Poster Presentation, WTC. Boston, MA: Conference Poster [Details] |
| Ryan JD, Zanabli AR, Cosio FG, Stegall MD, Larson TS, Griffin MD. (2007) Outcomes of immunosuppression reduction in BK viremic kidney transplant recipients screened at 4 months post-transplant. Poster Presentation, American Transplant Congress. San Francisco, CA: Conference Poster [Details] |
| Miller MN, Dong XD, Nath KA, Griffin MD. (2008) CCR6 identifies IL-17-competant effector memory T-cells in acutely obstructed kidneys. Poster Presentation, American Society of Nephrology Renal Week. Philadelphia, PA: Conference Poster [Details] |
| Issa N, Amer H, Dean PG, Kudva YC, Larson TS, Stegall MD, Habermann TM, Griffin MD. (2008) Improved survival for post-transplant lymphoproliferative disorder (PTLD) following pancreas transplantation. Poster Presentation, American Transplant Congress. Toronto, Canada: Conference Poster [Details] |
| Griffin MD, Park WD, Morlan B, Cosio FG, Stegall MD. (2008) Comparative gene expression analysis of histologically normal HLA-identical and non-identical living donor kidney transplants. Poster Presentation, American Transplant Congress. Toronto, Canada: Conference Poster [Details] |