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Dr Sanjeev Gupta B.Sc.,M.Sc.,Ph.D
Contact Details
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Biography:
Education 1997- 2002 Ph.D 1994- 1996 Master of Science (M. Sc.) Biochemistry 1991- 1994 Bachelor of Science (B. Sc.) Employment Post-doctoral fellow Kimmel Cancer Center, Thomas Jefferson University Assistant Professor Indian Institute of Technology-Madras (IIT-Madras), Senior Researcher School of Natural Sciences & NCBES, National University of Ireland, |
Peer Reviewed Journals
| Ganapati U, Gupta S, Radha V, Manogaran PS, Swarup G (2001) 'A Nuclear protein tyrosine phosphatase induces shortening of G1 phase and increase in c-myc protein level'. Experimental Cell Research, . [Details] |
| Gupta S, Radha V, Furukawa Y, Swarup G. (2001) 'Direct transcriptional activation of human caspase-1 by tumor suppressor p53'. Journal Of Biological Chemistry, . [Details] |
| Gupta S, Radha V, Sudhakar Ch, Swarup G. (2002) 'A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis'. Febs Letters, . [Details] |
| Jones JM, Datta P, Srinivasula SM, Ji W, Gupta S, Zhang Z, Davies E, Hajnóczky G, Saunders TL, Van Keuren ML, Fernandes-Alnemri T, Meisler MH, Alnemri ES. (2003) 'Loss of Omi/HtrA2 protease activity causes neuromuscular disorder in mnd2 mutant mice'. Nature, . [Details] |
| Srinivasula SM, Gupta S, Datta P, Zhang Z, Hegde R, Cheong N, Fernandes-Alnemri T, Alnemri ES (2003) 'Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2'. Journal Of Biological Chemistry, . [Details] |
| Gupta S, Singh R, Datta P, Zhang Z, Orr C, Lu Z, DuBois G, Zervos AS, Meisler MH, Srinivasula SM, Fernandes-Alnemri T, Alnemri ES (2004) 'The carboxy terminal tail of Presenilin regulates Omi/HtrA2 protease activity'. Journal Of Biological Chemistry, . [Details] |
| Cilenti L, Soundarapandian MM, Kyriazis GA, Stratico V, Singh S, Gupta S, Bonventre JV, Alnemri ES, Zervos AS (2004) 'Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death'. Journal Of Biological Chemistry, . [Details] |
| Sadasivam S, Gupta S, Radha V, Batta K, Kundu TK, Swarup G (2005) 'Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis'. Oncogene, . [Details] |
| Jain N, Gupta S, Sudhakar Ch, Radha V, Swarup G. (2005) 'Role of p73 in regulating human caspase-1 gene transcription induced by interferon-gamma and cisplatin'. Journal Of Biological Chemistry, . [Details] |
| Hu S, Du M-Q, Park S-M, Alcivar A, Qu L, Gupta S, Tang J, Baens M, Ye H, Lee TH, Marynen P, Riley JL, Yang X (2006) 'cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas'. Journal Of Clinical Investigation, . [Details] |
| Healy SJ, Gorman AM, Mousavi-Shafaei P, Gupta S, Samali A. (2009) 'Targeting the endoplasmic reticulum-stress response as an anticancer strategy'. European Journal Of Pharmacology, . [Details] |
| Szegezdi E, Macdonald DC, Ní Chonghaile T, Gupta S, Samali A. (2009) 'Bcl-2 family on guard at the ER'. American Journal Of Physiology: Cell Physiology, . [Details] |
| Gupta S, Kass GE, Szegezdi E, Joseph B. (2009) 'The mitochondrial death pathway: A promising therapeutic target in Diseases'. Journal Of Cellular And Molecular Medicine, . [Details] |
| Sanjeev Gupta. (2010) 'Pathologic impact of ER stress: regulation by Hsp72. (2010)'. Inflammation research : official journal of the European Histamine Research Society ... [et al.], . [Details] |
| Gupta, S; Gerlach, J; Miura, Y; Yamazaki, T; Nakahara, T; Asada, H; Samali, A; Joshi, L. (2010) 'High Throughput Glycanmap (R) Analysis of Glycosylation during ER Stress and Apoptosis in a Colon Cancer Model'. Glycobiology, . [Details] |
| Gupta S, Deepti A, Deegan S, Lisbona F, Hetz C, Samali A. (2010) 'HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction'. Plos Biology, . [Details] |
| Samali, A., Fitzgerald, U., Deegan, S., & Gupta, S. (2010) 'Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response'. International Journal Of Cell Biology, . [ARAN Link] [Details] |
| Gupta S, Cuffe L, Szegezdi E, Logue SE, Neary C, Healy S, Samali A (2010) 'Mechanisms of ER stress-mediated mitochondrial membrane permeabilization'. International Journal Of Cell Biology, . [Details] |
| Doyle KM, Kennedy D, Gorman AM, Gupta S, Healy SJ, Samali A (2011) 'Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders'. Journal Of Cellular And Molecular Medicine, . [Details] |
| Karen Cawley, Shane Deegan, Afshin Samali, Sanjeev Gupta (2011) 'Assays for detecting the unfolded protein response'. Methods In Enzymology, . [Details] |
| Ananya Gupta, Emer Caffrey, Grace Callagy, Sanjeev Gupta. (2012) 'Estrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'. Biochemical Society Transactions, . [Details] |