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Dr. Muriel Grenon PhD
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Biography:
Peer Reviewed Journals
| Tratner I, Piard K, Grenon M, Perderiset M, Baldacci G (1997) 'PCNA and DNA polymerase delta catalytic subunit from Schizosaccharomyces pombe do not interact directly'. Biochem, 231 (2):321-328. [DOI] [Details] |
| Francesconi S, Grenon M, Bouvier D, Baldacci G (1997) 'p56(chk1) protein kinase is required for the DNA replication checkpoint at 37 degrees C in fission yeast'. Embo Journal, 16 (6):1332-1341. [DOI] [Details] |
| Grenon M, Tillit J, Piard K, Baldacci G, Francesconi S (1999) 'The S/M checkpoint at 37 degrees C and the recovery of viability of the mutant poldeltats3 require the crb2+/rhp9+ gene in fission yeast'. Molecular & General Genetics, 260 (6):522-534. [Details] |
| Grenon, M,Gilbert, C,Lowndes, NF (2001) 'Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex'. Nature Cell Biology, 3 :844-847. [Details] |
| Chakraverty RK, Kearsey JM, Oakley TJ, Grenon M, de La Torre Ruiz MA, Lowndes NF, Hickson ID (2001) 'Topoisomerase III acts upstream of Rad53p in the S-phase DNA damage checkpoint'. Molecular And Cellular Biology, 21 (21):7150-7162. [DOI] [Details] |
| Francesconi S, Smeets M, Grenon M, Tillit J, Blaisonneau J, Baldacci G (2002) 'Fission yeast chk1 mutants show distinct responses to different types of DNA damaging treatments'. Gene, 7 (7):663-673. [Details] |
| Gilbert C, van den Bosch M. Green CM, Vialard JE, Grenon M, Erdjument-Bromage H, Tempst P and Lowndes NF (2003) 'The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function'. EMBO Reports, 4 :953-958. [DOI] [Details] |
| Grenon, M,Magill, CP,Lowndes, NF,Jackson, SP (2006) 'Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation'. Fems Yeast Research, 6 :836-847. [DOI] [Details] |
| Toh GW-L, O'Shaughnessy A, Jimeno S, Dobbie I, Grenon M, Maffini S, O' Rorke A and Lowndes, NF (2006) 'Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation'. DNA Repair, 5 :693-703. [DOI] [Details] |
| O'Shaughnessy AM, Grenon M, Gilbert C, Toh GW-L, Green CM and Lowndes NF (2006) 'Multiple approaches to study Scerevisiae Rad9, a prototypical checkpoint protein'. Meths Enzym, 409 :131-150. [Details] |
| Rossignol T, Logue ME, Reynolds K, Grenon M, Lowndes NF and Butler G (2007) 'Transcriptional response of Candida parapsilosis following exposure to farnesol'. Antimicrob Agents Chemother, 51 (7):2304-2312. [DOI] [Details] |
| Grenon, M,Costelloe, T,Jimeno, S,O'Shaughnessy, A,FitzGerald, J,Zgheib, O,Degerth, L,Lowndes, NF (2007) 'Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain'. Yeast, 24 :105-119. [DOI] [Details] |
| Rupnik A, Grenon M, Lowndes NF (2008) 'Quick Guide: The MRN complex'. Curr Biol, 18 (11):455-457. [Details] |
FitzGerald, J. E.,Grenon, M.,Lowndes, N. F. (2009) '53BP1: function and mechanisms of focal recruitment'. Biochemical Society Transactions, 37 :897-904. [Details] |
| Granata M, Lazzaro F, Novarina D, Panigada D, Puddu F, Abreu CM, Kumar R, Grenon M, Lowndes NF, Pleyani P, Muzi-Falconi M (2010) 'Dynamics of RAD9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity'. PLoS Genetics, 6 (8). [DOI] [Details] |
| Rupnik A, Lowndes NF, Grenon M. 2010 Apr,119(2):115-35. Epub 2009 Oct 28. Review. PubMed PMID: 19862546. (2010) 'MRN and the race to the break'. Chromosoma, 119 (2):115-135. [Details] |
Finn, K., Lowndes, N.F., Grenon, M. (2011) 'Eukaryotic DNA damage checkpoint activation in response to double-strand breaks'. Cellular and Molecular Life Sciences, :1-27. [Details] |
| FitzGerald, J., Moureau, S., Drogaris, P., O'Connell, E., Abshiru, N., Verreault, A., et al. (2011) 'Regulation of the DNA Damage Response and Gene Expression by the Dot1L Histone Methyltransferase and the 53Bp1 Tumour Suppressor'. PLoS ONE, 6 (2). [ARAN Link] [Details] |

