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Dr. Thomas Barry
Contact Details
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Biography:
| Dr. Barry is a research director and a founder member of the
Molecular Diagnostics Research Group (MDRG) at NUIG. This research group
consists of 2 senior research postdoctoral scientists, 8 postdoctoral
scientists, 4 research assistants and 4 PhD students. Research interests are
primarily focused on the research, development and commercialisation of
platform nucleic acid based diagnostics technologies for the detection and
identification of microbial agents. Dr. Barry is the inventor of the microbial
platform nucleic acid based diagnostics, Internal Transcribed Spacer-Probe,
RiboSEQ, MycoTECH, MycoSEQ and RiboTECH technologies. |
Peer Reviewed Journals
| Mc Evoy, T. G., Stack, M., Keane, B., Barry, T., Sreenan, J. M. and Gannon, F. (1988) 'THE EXPRESSION OF A FOREIGN GENE IN SALMON EMBRYOS'. Aquaculture, . [Details] |
| BARRY, T,STACK, M,MORGAN, A,GANNON, F (1989) 'THE IDENTIFICATION OF CDNA CLONES THAT INCLUDE THE 3' END OF MESSENGER-RNA'. Gene Analysis Techniques, 6 :21-23. [Details] |
| Gannon, F.;Powell, R.; Barry, T.; McEvoy, T.G.; Sreenan, J.M. (1990) 'Transgenic farm animals'. Journal Of Biotechnology, . [Details] |
| BARRY, T,POWELL, R,GANNON, F (1990) 'A GENERAL-METHOD TO GENERATE DNA PROBES FOR MICROORGANISMS'. Nature Biotechnology, 8 :233-236. [Details] |
| Powell, R., Byrnes, L., Barry, T. and Gannon, F. (1990) 'A rapid procedure to isolate major abundance mRNA transcripts and study the transcription profile of a tissue'. Technique, . [Details] |
| Barry, T., Colleran, G. C., Glennon, M., Dunican, L. K. D. and Gannon, F. (1991) 'The 16s/23s ribosomal spacer region as a target for DNA probes to identify eubacteria'. Genome Research, . [Details] |
| Cormican, M. G., Barry, T., Gannon, F. and Flynn, J. (1991) 'RAPID IDENTIFICATION OF CULTURED MYCOBACTERIUM-TUBERCULOSIS BY SPECIFIC PRIMER DIRECTED DNA AMPLIFICATION'. Journal Of Medical Microbiology, . [Details] |
| Cormican, M. G., Barry, T., Gannon, F. and Flynn, J. (1992) 'USE OF POLYMERASE CHAIN-REACTION FOR EARLY IDENTIFICATION OF MYCOBACTERIUM-TUBERCULOSIS IN POSITIVE CULTURES'. Journal Of Clinical Pathology, . [Details] |
| Barry, T., Geary, S., Hannify, S., MacGearailt, Shalloo, M., Heery, D., Gannon, F. and Powell, P. (1992) 'RAPID MINI-PREPARATIONS OF TOTAL RNA FROM BACTERIA'. Nucleic Acid Research, . [Details] |
| Barry, T., Glennon, M., Smith, T. and Gannon, F. (1993) 'DETECTION OF MYCOBACTERIUM-BOVIS IN BOVINE BLOOD BY COMBINED PCR AND DNA PROBE METHODS'. Veterinary Record, . [Details] |
| Glennon, M., Smith, T., Cormican, M., Noone, D., Barry, T., Maher, M., Dawson, M., Gilmartin, J.J., and Gannon F. (1994) 'THE RIBOSOMAL INTERGENIC SPACER REGION - A TARGET FOR THE PCR BASED DIAGNOSIS OF TUBERCULOSIS'. Tubercle And Lung Disease, . [Details] |
| Barry, T,Kelly, M,Glynn, B,Peden, J (1999) 'Molecular cloning and phylogenetic analysis of the small cytoplasmic RNA from Listeria monocytogenes'. Fems Microbiology Letters, 173 :47-53. [Details] |
| Glynn, B., Lahiff, S., Wernecke, M., Barry, T., Smith, T.J. and Maher M. (2006) 'Current and emerging molecular diagnostic technologies applicable to bacterial food safety'. Int. J. Dairy Tech, 59 :126-139. [Details] |
| Casserly, G., Barry, T., Tourtellotte W.W., Hogan, E.L. (2007) 'Absence of Mycoplasma-specific DNA sequence in brain, blood and CSF of patients with multiple sclerosis (MS): A study by PCR and Real-time PCR'. J. Neurol. Sci, 15 (253(1-2)):48-52. [Details] |
| Barry Glynn, Katrina Lacey, Joanna Reilly, Terry J Smith, Thomas Barry, and Majella Maher (2007) 'Quantification of Bacterial tmRNA using in vitro Transcribed RNA Standards and Two-Step qRT-PCR'. Research Journal Of Biological Sciences, 2 (5):564-570. [Details] |
| Edel O' Regan, Evonne Mc Cabe, Catherine Burgess, Sheila Mc Guinness, Thomas Barry, Geraldine Duffy, Paul Whyte and Seamus Fanning. (2008) 'Development of a real-time multiplex PCR assay for the detection of multiple Salmonella serotypes in chicken samples'. Bmc Microbiology, 8 (156). [Details] |
| Barry Glynn, Katrina Lacey, Justin O Grady, Thomas Barry, Terry J Smith, and Majella Maher. (2008) 'Reusable lateral flow chip assay for the specific detection of Streptococcus pneumoniae tmRNA'. Journal Of Rapid Methods & Automation In Microbiology, 16 :210-221. [Details] |
| Glynn, B., Scheler, O., Parkel, S., Kurg, A., Barry, T., Smith, T., Maher, M. (2008) 'Microarray Detection of Labeled NASBA Products for the Specific Identification of Pathogenic Bacteria using tmRNA as a target'. Sensors, :1072-1075. [Details] |
| O' Grady, J., Maher, M., Smith, T and Barry T. (2008) 'Rapid real-time PCR detection of Listeria monocytogenes in enriched food samples based on the ssr A gene, a novel diagnostic target'. International Journal Of Food Microbiology, 25 :75-84. [DOI] [Details] |
| Dolan, A., Burgess, C.M., Barry, T., Fanning, S. and Duffy, G. (2009) 'A novel quantitative reverse-transcription PCR (qRT-PCR) for the enumeration of total bacteria, using meat micro-flora as a model'. J Microbiol Methods, 77 :1-7. [DOI] [Details] |
| O'Grady, J., Lacey, K., Glynn, B., Smith, T., J., Barry, T. & Maher, M. (2009) 'tmRNA - a novel high-copy-number RNA diagnostic target - its application for Staphylococcus aureus detection using real-time NASBA'. Fems Microbiology Letters, 301 :218-223. [Details] |
| Wernecke, M., Mullen, C., Sharma, V., Morrison, J., Barry, T., Maher, M. and Smith, T (2009) 'Evaluation of a novel real-time PCR test based on the ssrA gene for the identification of group B streptococci in vaginal swabs'. Bmc Infectious Diseases, 9 (148). [DOI] [Details] |
| McGuinness, S., McCabe, E., 0' Regan, E., Dolan, A., Duffy, G., Burgess, C., Fanning, S., Barry, T. and O'Grady, J. (2009) 'Development and validation of a rapid real-time PCR based method for the specific detection of Salmonella on fresh meat'. Meat Science, 83 :555-562. [DOI] [Details] |
| Justin O'Grady, Margaret Ruttledge, Sara Sedano-Balba´s, Terry J. Smith, Thomas Barry, Majella Maher. (2009) 'Rapid detection of Listeria monocytogenes in food using culture enrichment combined with real-time PCR'. Food Microbiology, 26 :4-7. [DOI] [Details] |
| McGuinness, S., Barry, T. and O’Grady, J (2010) 'Development and preliminary validation of a rapid real-time RT-PCR based method targeting tmRNA for the specific detection of Salmonella'. Food Research International, . [Details] |
| McCabe, E. M., Burgess, C., D., O'Regan, E., McGuinness, S., Barry, T., Fanning, S. and Duffy, G. (2011) 'Development and evaluation of DNA and RNA real-time assays for food analysis using the hilA gene of Salmonella enterica subspecies enterica'. Food Microbiology, . [Details] |
| McCabe, E. M., Burgess, C. M., Walsh, D., O'Regan, E., McGuinness, S., Barry, T., Fanning, S. and Duffy, G. (2011) 'Validation of DNA and RNA real-time assays for food analysis using the hilA gene of Salmonella enterica serovars'. Journal Of Microbiological Methods, . [Details] |
| Spain, E., Kojima, R., Kaner, R.B., Wallace, G.G., O’Grady, J., Lacey, K., Barry, T., Keyes, T.E. and Forster, R.J. (2011) 'High Sensitivity DNA Detection Using Gold Nanoparticle Functionalized Polyaniline Nanofibres'. Biosensors & Bioelectronics, . [Details] |
| Scheler, O., Kaplinski, L., Glynn, B., Palta, P., Parkel, S., Toome, K., Maher, M., Barry, T., Remm, M. and Kurg, A. (2011) 'Detection of NASBA amplified bacterial tmRNA molecules on SLICSel designed microarray probes'. Bmc Biotechnol, . [Details] |
| Reddington, K., O’Grady, J., Dorai-Raj, S., Maher, M., van Soolingen, D. and Barry, T. (2011) 'A novel multiplex real-time PCR diagnostics assay for the identification and differentiation of Mycobacterium tuberculosis, Mycobacterium canettii and the Mycobacterium tuberculosis complex'. Journal Of Clinical Microbiology, . [Details] |
| Reddington K, O'Grady J, Dorai-Raj S, Niemann S, van Soolingen D. and Barry, T. (2011) 'A Novel Multiplex Real-Time PCR for the Identification of Mycobacteria Associated with Zoonotic Tuberculosis'. Plos One, . [Details] |
| Clancy, E., Glynn, B., Reddinton, K., Smith, T. and Barry, T. (2012) 'Culture confirmation of Listeria monocytogenes using tmRNA as a diagnostics target'. Journal Of Microbiological Methods, 88 :427-429. [Details] |
Conference Publications
| Glynn, B., Lacey, K., Palta, P., Kaplinski, L., Remm, M., Barry, T., Smith, T. and Maher M. Demonstration of the application of the tmRNA transcript of the bacterial ssrA gene as a molecular diagnostic target using a combination of NASBA and BiaCore technologies. European Conference of Clinical Microbiology and Infectious Diseases Munich, Germany, [Details] |
Conference Paper
| Phelan, D., Glynn, B., Papkovsky, D., A., A., Morgan, F., Redfern, M. & Barry, T. An integrated Research Strategy for the Development of Small to Medium Sized Nucleic Acid Microarrays for Diagnostics. Western Alliance in NCBES. NUIG: Conference Paper [Details] |
| Glynn, B., O' Grady, J., Lacey, K., Maher, M., Barry, T. and Smith, T. SLIC Biosensors in Molecular Diagnostics: Nanotechnology for analysis of species-specific microbial transcripts. International Sensors Workshop. DCU: Conference Paper [Details] |
| O' Grady, J., Lacey, K., Lahiff, S., Glynn, B., Maher, M. Barry, T. and Smith T. Sandwich ELISA based on the RiboSEQ platform for direct detection of Staphylococcus aureus. International Sensors Workshop. DCU: Conference Paper [Details] |
| O' Grady, J., Lacey, K., Lahiff, S., Glynn, B., Maher, M. Barry, T. and Smith T. Sandwich ELISA based on the RiboSEQ platform for direct detection of Staphylococcus aureus. Science Faculty Research Day. NUI Galway: Conference Paper [Details] |
| Dorai-Raj, S., O'Grady, J., Glynn, B., O'Connor, L., Maher, M., Smith, T. & Barry, T. tmRNA - A Novel Nucleic Acid Target for Eubacterial Diagnostics. Emerging Issues in Food Safety. Cork, Ireland: Conference Paper [Details] |
| Bohane, H., O'Connor, L., Barry, T., Glennon, M., Cormican, M., Smith, T. & Maher, M. tmRNA a Novel Target for Rapid Diagnosis of the Mycobacterium tuberculosis Complex. SGM Irish Branch Meeting. Conference Paper [Details] |
| Wernecke, M., Mullen, C., Maher, M., Barry, T. and Smith, T. Development and validation of a real-time PCR assay for the detection of Group B Streptococcus in pregnant women. Science Faculty Research Day. NUI Galway: Conference Paper [Details] |
| Kelliher, F., Glynn, B., Smith, T. & Barry, T. tmRNA as an indicator of bacterial viability - A preliminary experimental analysis. SGM Irish Branch Meeting. Conference Paper [Details] |
| Wernecke, M., Mullen, C., Maher, M., Barry, T. and Smith, T. Development and validation of a real-time PCR assay for the detection of Group B Streptococcus in pregnant women. European Conference of Clinical Microbiology and Infectious Diseases. Munich, Germany: Conference Paper [Details] |
| Mullen, C., Wernecke, M., Morrison, J., Sharma, V., Barry, T., Smith, T. and Maher, M. Development of a real-time PCR assay for the identification of Group B Streptococcus in pregnant women. Society of General Microbiology Meeting. University of Limerick: Conference Paper [Details] |