Dr. Andrea Erxleben

Ph.D., B.Sc.

Contact Details

Lecturer Above The Bar
School of Chemistry
Room 150
Arts/Science Building
NUI Galway

T: Ext. 2483
E: andrea.erxleben@nuigalway.ie
 
researcher

Biography


  • since 2007: Lecturer in Inorganic Chemistry, NUI Galway
  • 2004: Visiting Professor, Institute of Inorganic Chemistry of the University of Vienna, Austria
  • 2002 - 2006: “Privatdozent”, University of Dortmund, Germany
  • 2002:  “Habilitation”, University of Dortmund, Germany
  • 1995 - 1997: Postdoctoral fellow, McGill University, Montréal
  • 1995: Dr. rer. nat. (PhD), University of Dortmund, Germany
  • 1992: "Dipl.-Chem", University of Dortmund, Germany

 

Research Interests

My research interests comprise Medicinal Inorganic Chemistry and Pharmaceutical Solid State Chemistry. Research activities in the area of Medicinal Inorganic Chemistry are centered on the synthesis and study of anticancer metallodrugs. A specific focus is on the development of new Pt(IV) anticancer pro-drugs with reduced side effects, metal complexes with receptor-specific carriers for target-delivery and selective accumulation into cancer tissue and on metal complexes that exhibit anticancer activity by irreversibly cleaving the tumour cell DNA. My research activities in the field of solid state chemistry of pharmaceuticals are aimed at improving the bioavailability and thus the therapeutic efficacy of poorly soluble drugs, including antibiotics, via co-amorphisation, co-crystallisation, control of crystal size and habit and polymoprh control.

Research Projects

  Project Start Date End Date
13th International Symposium on Applied Bioinorganic Chemistry (ISABC13) 01-APR-15 30-SEP-15
Saudi Arabia - Marwah Hamdam Mohammad Aljohani - Andrea Erxleben (PI) 05-JAN-15 04-JAN-19
ROYAL EMBASSY OF SAUDI ARABIA AWATIF RASHED ZABIN ALMOTAIRY A ERXLEBEN 01-SEP-14 31-AUG-16
SYNTHESIS AND SOLID STATE PHARMACEUTICAL CENTRE(SSPC) A ERXLEBEN 01-JUN-13 31-MAY-19
SYNTHESIS & SOLID STATE PHARMACEUTICAL CENTRE(SSPC) INDUSTRY ACCOUNT A ERXLEBEN 01-JUN-13 31-MAY-19
SYNTHESIS AND BIOLOGICAL ACTIVITY OF CU(ii) METALLONUCLEASES A ERXLEBEN 01-JUN-13 13-MAR-14
SFI INCOMING SHORT TERM TRAVEL FELLOWSHIP 07 SK B1191-ISTFF 11 ANDREA ERXLEBEN 01-JAN-12 25-FEB-14
STOKES LECTURESHIP IN MEDICINAL CHEMISTRY 01-SEP-08 30-JUN-15
QUALIFICATION OF DIFFERENT SOLID STATE FORMS 5 MERCAPTOPURINE BY NEAR INFRARED SPECTROSCOPY COMBINED WITH MULTIVARIATE ANALYSIS A ERXLEBEN 03-JUN-13 23-JUL-13
FUNCTIONALIZED LOCKED NUCLEIC ACIDS, ANDREA ERXLEBEN 01-SEP-11 30-NOV-15
IRCSET EMBARK POSTGRAD NOEL BRYNE A ERXLEBEN 01-OCT-09 30-SEP-13
IRCSET FELLOWSHIP ROBERT WHIRISKEY ANDREA ERXLEBEN 01-OCT-08 02-NOV-13
MF08P03 CATALYSTS FOR DNA CLEAVAGE A ERXLEBEN 01-JAN-09 31-DEC-09

Peer Reviewed Journals

  Year Publication
(2015) 'Anisotropic Crystal Growth in Flat and Nonflat Systems: The Important Influence of van der Waals Contact Molecular Stacking on Crystal Growth and Dissolution'
Walshe, N,Crushell, M,Karpinska, J,Erxleben, A,McArdle, P (2015) 'Anisotropic Crystal Growth in Flat and Nonflat Systems: The Important Influence of van der Waals Contact Molecular Stacking on Crystal Growth and Dissolution'. Crystal Growth & Design, 15 :3235-3248 [DOI] [Details]
(2015) 'DNA damage and induction of apoptosis in pancreatic cancer cells by a new dinuclear bis(triazacyclonane) copper complex'
Montagner, D,Gandin, V,Marzano, C,Erxleben, A (2015) 'DNA damage and induction of apoptosis in pancreatic cancer cells by a new dinuclear bis(triazacyclonane) copper complex'. Journal Of Inorganic Biochemistry, 145 :101-107 [DOI] [Details]
(2015) 'Sulfamerazine: Understanding the Influence of Slip Planes in the Polymorphic Phase Transformation through X-Ray Crystallographic Studies and ab Initio Lattice Dynamics'
Pallipurath, AR,Skelton, JM,Warren, MR,Kamali, N,McArdle, P,Erxleben, A (2015) 'Sulfamerazine: Understanding the Influence of Slip Planes in the Polymorphic Phase Transformation through X-Ray Crystallographic Studies and ab Initio Lattice Dynamics'. Molecular Pharmaceutics, 12 :3735-3748 [DOI] [Details]
(2015) 'Crystalline adducts of the Lawsone molecule(2-hydroxy-1,4-naphthaquinone): optical properties and computational modelling'
Pallipurath, A,Skelton, JM,Delori, A,Duffy, C,Erxleben, A,Jones, W (2015) 'Crystalline adducts of the Lawsone molecule(2-hydroxy-1,4-naphthaquinone): optical properties and computational modelling'. Crystengcomm, 17 :7684-7692 [DOI] [Details]
(2015) 'Hydrogen Bonding Networks and Solid-State Conversions in Benzamidinium Salts'
Kamali, N,Aljohani, M,McArdle, P,Erxleben, A (2015) 'Hydrogen Bonding Networks and Solid-State Conversions in Benzamidinium Salts'. Crystal Growth & Design, 15 :3905-3916 [DOI] [Details]
(2015) 'Cytotoxicity and antimicrobial activity of triorganotin(IV) complexes of phenylcyanamide prepared by sonochemical synthesis'
Tabrizi, L,McArdle, P,Erxleben, A,Chiniforoshan, H (2015) 'Cytotoxicity and antimicrobial activity of triorganotin(IV) complexes of phenylcyanamide prepared by sonochemical synthesis'. Inorganica Chimica Acta, 438 :94-104 [DOI] [Details]
(2015) 'Water-based ultrasonic synthesis of SbSI nanoneedles'
Gladkovskaya, O., Rybina, I., Gun'Ko, Y.K., Erxleben, A., O'Connor, G.M., Rochev, Y. (2015) 'Water-based ultrasonic synthesis of SbSI nanoneedles'. Materials Letters, 160 (27):113-116 [DOI] [Details]
(2015) 'Water-based ultrasonic synthesis of SbSI nanoneedles'
Gladkovskaya, O,Rybina, I,Gun'ko, YK,Erxleben, A,O'Connor, GM,Rochev, Y (2015) 'Water-based ultrasonic synthesis of SbSI nanoneedles'. Materials Letters, 160 :113-116 [DOI] [Details]
(2015) 'Nickel(II) and cobalt(II) complexes of lidocaine: Synthesis, structure and comparative in vitro evaluations of biological perspectives'
Tabrizi, L,McArdle, P,Erxleben, A,Chiniforoshan, H (2015) 'Nickel(II) and cobalt(II) complexes of lidocaine: Synthesis, structure and comparative in vitro evaluations of biological perspectives'. European Journal Of Medicinal Chemistry, 103 :516-529 [DOI] [Details]
(2014) 'Mechanochemical Reaction of Sulfathiazole with Carboxylic Acids: Formation of a Cocrystal, a Salt, and Coamorphous Solids'
Hu, Y,Gniado, K,Erxleben, A,McArdle, P (2014) 'Mechanochemical Reaction of Sulfathiazole with Carboxylic Acids: Formation of a Cocrystal, a Salt, and Coamorphous Solids'. Crystal Growth & Design, 14 :803-813 [DOI] [Details]
(2014) 'Phosphate Diester Cleavage, DNA Interaction and Cytotoxic Activity of a Bimetallic Bis(1,4,7-triazacyclononane) Zinc Complex'
Montagner, D,Gandin, V,Marzano, C,Erxleben, A (2014) 'Phosphate Diester Cleavage, DNA Interaction and Cytotoxic Activity of a Bimetallic Bis(1,4,7-triazacyclononane) Zinc Complex'. European Journal Of Inorganic Chemistry, :4084-4092 [DOI] [Details]
(2014) 'Effects of Ball-Milling and Cryomilling on Sulfamerazine Polymorphs: A Quantitative Study'
Macfhionnghaile, P,Hu, Y,Gniado, K,Curran, S,Mcardle, P,Erxleben, A (2014) 'Effects of Ball-Milling and Cryomilling on Sulfamerazine Polymorphs: A Quantitative Study'. Journal Of Pharmaceutical Sciences, 103 :1766-1778 [DOI] [Details]
(2014) 'Nanomechanical properties of poly (lactic-co-glycolic) acid film during degradation'
Reyhaneh N. Shirazi, Fawaz Aldabbagh, Andrea Erxleben, Yuri Rochev, Peter E. McHugh (2014) 'Nanomechanical properties of poly (lactic-co-glycolic) acid film during degradation'. Acta Biomaterialia, 10 :4695-4703 [DOI] [Details]
(2013) 'Formation, physical stability, and quantification of process-induced disorder in cryomilled samples of a model polymorphic drug'
Hu, Y,Macfhionnghaile, P,Caron, V,Tajber, L,Healy, AM,Erxleben, A,McArdle, P (2013) 'Formation, physical stability, and quantification of process-induced disorder in cryomilled samples of a model polymorphic drug'. Journal Of Pharmaceutical Sciences, 102 :93-103 [DOI] [Details]
(2013) 'Solvent-dependent Switch of Magnesium Ions between Different Binding Sites in a Compartmental Schiff Base Ligand'
Coleman, F,Dux, D,Erxleben, A (2013) 'Solvent-dependent Switch of Magnesium Ions between Different Binding Sites in a Compartmental Schiff Base Ligand'. Zeitschrift Fur Anorganische Und Allgemeine Chemie, 639 :1584-1589 [DOI] [Details]
(2013) 'Applications of Low Temperature Gradient Sublimation in Vacuo: Rapid Production of High Quality Crystals. The First Solvent-Free Crystals of Ethinyl Estradiol'
Karpinska, J,Erxleben, A,McArdle, P (2013) 'Applications of Low Temperature Gradient Sublimation in Vacuo: Rapid Production of High Quality Crystals. The First Solvent-Free Crystals of Ethinyl Estradiol'. Crystal Growth & Design, 13 :1122-1130 [DOI] [Details]
(2013) 'A comprehensive near infrared spectroscopic study of the limits of quantitative analysis of sulfathiazole polymorphism'
MacFhionnghaile, P,Hu, Y,McArdle, P,Erxleben, A (2013) 'A comprehensive near infrared spectroscopic study of the limits of quantitative analysis of sulfathiazole polymorphism'. Journal Of Near Infrared Spectroscopy, 21 :55-66 [DOI] [Details]
(2013) 'Amorphous Solid Dispersions of Sulfonamide/Soluplus (R) and Sulfonamide/PVP Prepared by Ball Milling'
Caron, V,Hu, Y,Tajber, L,Erxleben, A,Corrigan, OI,McArdle, P,Healy, AM (2013) 'Amorphous Solid Dispersions of Sulfonamide/Soluplus (R) and Sulfonamide/PVP Prepared by Ball Milling'. Aaps Pharmscitech, 14 :464-474 [DOI] [Details]
(2013) 'Solid-State Transformations of Sulfathiazole Polymorphs: The Effects of Milling and Humidity'
Hu, Y, Erxleben, A, Hodnett, BK, Li, BY, McArdle, P, Rasmuson, AC, Ryder, AG (2013) 'Solid-State Transformations of Sulfathiazole Polymorphs: The Effects of Milling and Humidity'. Crystal Growth & Design, 13 :3404-3413 [DOI] [Details]
(2013) 'Investigation of the Capacity of Low Glass Transition Temperature Excipients to Minimize Amorphization of Sulfadimidine on Comilling'
Curtin, V,Amharar, Y,Hu, Y,Erxleben, A,McArdle, P,Caron, V,Tajber, L,Corrigan, OI,Healy, AM (2013) 'Investigation of the Capacity of Low Glass Transition Temperature Excipients to Minimize Amorphization of Sulfadimidine on Comilling'. Molecular Pharmaceutics, 10 :386-396 [DOI] [Details]
(2012) 'Rapid hydrolysis of phosphate monoesters by zirconium(IV) complexes in neutral solution'
Coleman, F,Erxleben, A (2012) 'Rapid hydrolysis of phosphate monoesters by zirconium(IV) complexes in neutral solution'. Polyhedron, 48 :104-109 [DOI] [ARAN Link] [Details]
(2011) '17 beta-Hydroxy-17 alpha-methylandrostano[3,2-c]pyrazole, Stanozolol: The Crystal Structures of Polymorphs 1 and 2 and 10 Solvates'
Karpinska, J,Erxleben, A,McArdle, P (2011) '17 beta-Hydroxy-17 alpha-methylandrostano[3,2-c]pyrazole, Stanozolol: The Crystal Structures of Polymorphs 1 and 2 and 10 Solvates'. Crystal Growth & Design, 11 :2829-2838 [DOI] [Details]
(2011) 'Hydrogen bond directed honeycomb-like porous network structure of tris (bipyridyl-glycoluril)cobalt(III) chloride'
Kawade, VA,Kumbhar, AS,Erxleben, A,Pachfule, P,Banerjee, R (2011) 'Hydrogen bond directed honeycomb-like porous network structure of tris (bipyridyl-glycoluril)cobalt(III) chloride'. Crystengcomm, 13 :5289-5291 [DOI] [Details]
(2011) 'Supramolecular Structures and Tautomerism of Carboxylate Salts of Adenine and Pharmaceutically Relevant N-6-Substituted Adenine'
McHugh, C,Erxleben, A (2011) 'Supramolecular Structures and Tautomerism of Carboxylate Salts of Adenine and Pharmaceutically Relevant N-6-Substituted Adenine'. Crystal Growth & Design, 11 :5096-5104 [DOI] [ARAN Link] [Details]
(2011) 'Mixed ligand cobalt(II) picolinate complexes: synthesis, characterization, DNA binding and photocleavage'
Kawade, VA,Kumbhar, AA,Kumbhar, AS,Nather, C,Erxleben, A,Sonawane, UB,Joshi, RR (2011) 'Mixed ligand cobalt(II) picolinate complexes: synthesis, characterization, DNA binding and photocleavage'. Dalton Transactions, 40 :639-650 [DOI] [Details]
(2011) 'Mixed ligand cobalt(ii) picolinate complexes: Synthesis, characterization, DNA binding and photocleavage'
Kawade,V.A.,Kumbhar, A.A.,Kumbhar, A.S.,Nather,C.,Erxleben, A.,Sonawane, U.B.,Joshi, R.R. (2011) 'Mixed ligand cobalt(ii) picolinate complexes: Synthesis, characterization, DNA binding and photocleavage'. Dalton Transactions, 40 (3):639-650 [DOI] [Details]
(2010) 'Quantitative Analysis of Sulfathiazole Polymorphs in Ternary Mixtures by Attenuated Total Reflectance Infrared, Near-infrared and Raman Spectroscopy'
Hu, Y., Erxleben, A., Ryder, A.G., McArdle, P. (2010) 'Quantitative Analysis of Sulfathiazole Polymorphs in Ternary Mixtures by Attenuated Total Reflectance Infrared, Near-infrared and Raman Spectroscopy'. Journal of pharmaceutical and biomedical analysis, 53 (3):412-420 [DOI] [Details]
(2010) 'Binding and hydrolysis studies of antitumoural titanocene dichloride and Titanocene Y with phosphate diesters'
Erxleben, A,Claffey, J,Tacke, M (2010) 'Binding and hydrolysis studies of antitumoural titanocene dichloride and Titanocene Y with phosphate diesters'. Journal Of Inorganic Biochemistry, 104 :390-396 [DOI] [Details]
(2010) 'Synthesis, single-crystal and solution structure analysis and in vitro cytotoxic activity of two novel complexes of ruthenium(II) with in situ formed flavanone-based ligands'
Ochocki, J,Kasprzak, M,Checinska, L,Erxleben, A,Zyner, E,Szmigiero, L,Garza-Ortiz, A,Reedijk, J (2010) 'Synthesis, single-crystal and solution structure analysis and in vitro cytotoxic activity of two novel complexes of ruthenium(II) with in situ formed flavanone-based ligands'. Dalton Transactions, 39 :9711-9718 [DOI] [Details]
(2010) 'Ga-III Complexes as Models for the M-III Site of Purple Acid Phosphatase: Ligand Effects on the Hydrolytic Reactivity Toward Bis(2,4-dinitrophenyl) phosphate'
Coleman, F,Hynes, MJ,Erxleben, A (2010) 'Ga-III Complexes as Models for the M-III Site of Purple Acid Phosphatase: Ligand Effects on the Hydrolytic Reactivity Toward Bis(2,4-dinitrophenyl) phosphate'. Inorganic Chemistry, 49 :6725-6733 [DOI] [ARAN Link] [Details]
(2009) 'Synthesis, Crystal Structure and Electrochemical Studies of a Hydrazone Schiff Base Complex of Titanium(IV)'
Monfared, HH,Nazari, M,Mayer, P,Kamyabi, MA,Erxleben, A,Asgari, Z (2009) 'Synthesis, Crystal Structure and Electrochemical Studies of a Hydrazone Schiff Base Complex of Titanium(IV)'. Zeitschrift Fur Naturforschung Section B-A Journal Of Chemical Sciences, 64 :409-414 [Details]
(2009) 'Copper coordination to the aldehyde and hemiacetal form of 4-bromo-2-[(2-diethylaminoethyl)ethylaminomethyl]-6-formylphenol: Synthesis and structure of [Cu(H2L)(2)(X)(2)]X-2 center dot nH(2)O (X= NO3-, CIO4- and [Cu(L ')](2) center dot 2CH(3)OH'
Erxleben, A (2009) 'Copper coordination to the aldehyde and hemiacetal form of 4-bromo-2-[(2-diethylaminoethyl)ethylaminomethyl]-6-formylphenol: Synthesis and structure of [Cu(H2L)(2)(X)(2)]X-2 center dot nH(2)O (X= NO3-, CIO4- and [Cu(L ')](2) center dot 2CH(3)OH'. Inorganica Chimica Acta, 362 :839-844 [DOI] [Details]
(2009) 'Copper coordination to the aldehyde and hemiacetal form of 4-bromo-2-[(2-diethylaminoethyl)ethylaminomethyl]-6-formylphenol: Synthesis and structure of [Cu(H2L)(2)(X)(2)]X-2 center dot nH(2)O (X= NO3-, CIO4- and [Cu(L ')](2) center dot 2CH(3)OH'
Erxleben, A. (2009) 'Copper coordination to the aldehyde and hemiacetal form of 4-bromo-2-[(2-diethylaminoethyl)ethylaminomethyl]-6-formylphenol: Synthesis and structure of [Cu(H2L)(2)(X)(2)]X-2 center dot nH(2)O (X= NO3-, CIO4- and [Cu(L ')](2) center dot 2CH(3)OH'. Inorganica Chimica Acta, 362 (33):839-844 [Details]
(2009) 'Synthesis, spectroscopy and magnetism of novel metal complexes of 3-aminoflavone (3-af). X-ray crystal structure of 3-af and [Cu(3-af)(2)(NO3)(2)]'
Zurowska, B,Erxleben, A,Glinka, L,Leczycka, M,Zyner, E,Ochocki, J (2009) 'Synthesis, spectroscopy and magnetism of novel metal complexes of 3-aminoflavone (3-af). X-ray crystal structure of 3-af and [Cu(3-af)(2)(NO3)(2)]'. Inorganica Chimica Acta, 362 :739-744 [DOI] [Details]
(2009) 'Synthesis, crystal structure and electrochemical studies of a hydrazone schiff base complex of titanium(IV)'
Monfared,H.H.,Nazari, M.,Mayer, P.,Kamyabi, M.-A.,Erxleben, A.,Asgari, Z. (2009) 'Synthesis, crystal structure and electrochemical studies of a hydrazone schiff base complex of titanium(IV)'. Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 64 (4):409-414 [Details]
(2009) 'Synthesis, Crystal Structure and Electrochemical Studies of a Hydrazone Schiff Base Complex of TitaniumIV) Zeitschrift für Naturforschung B: A'
Monfared,H.H, Nazari,M, Mayer,P, Kamyabi,M.A, Erxleben,A, Asgari,Z. (2009) 'Synthesis, Crystal Structure and Electrochemical Studies of a Hydrazone Schiff Base Complex of TitaniumIV) Zeitschrift für Naturforschung B: A'. Journal of Chemical Sciences, 64 :409-414 [Details]
(2009) 'Invited contribution to the special issue dedicated to Bernhard Lippert “Cu coordination to the aldehyde and hemiacetal form of 4-bromo-2-[2-diethylaminoethyl)ethylaminomethyl]-6-formylphenol: synthesis and structure of [CuHL)2X)2] X = NO3, ClO4) and [CuL’)]2”'
Erxleben,A. (2009) 'Invited contribution to the special issue dedicated to Bernhard Lippert “Cu coordination to the aldehyde and hemiacetal form of 4-bromo-2-[2-diethylaminoethyl)ethylaminomethyl]-6-formylphenol: synthesis and structure of [CuHL)2X)2] X = NO3, ClO4) and [CuL’)]2”'. Inorg. Chim. Acta, 362 :839-844 [Details]
(2009) 'Copper coordination to the aldehyde and hemiacetal form of 4-bromo-2-[(2-diethylaminoethyl)ethylaminomethyl]-6-formylphenol: Synthesis and structure of [Cu(H2L)2(X)2] X2 · nH2O (X = NO3-, CIO4-) and [Cu(L?)]2 · 2CH3OH'
Erxleben,A. (2009) 'Copper coordination to the aldehyde and hemiacetal form of 4-bromo-2-[(2-diethylaminoethyl)ethylaminomethyl]-6-formylphenol: Synthesis and structure of [Cu(H2L)2(X)2] X2 · nH2O (X = NO3-, CIO4-) and [Cu(L?)]2 · 2CH3OH'. Inorganica Chimica Acta, 362 (3):839-844 [DOI] [Details]
(2007) 'Spontaneous reduction of mixed 2,2?-bipyridine/methylamine/chloro complexes of PtIV in water in the presence of light is accompanied by complex isomerization, loss of methylamine, and formation of a strong oxidant, presumably HOCl'
Nakabayashi,Y.,Erxleben, A.,Letinois, U.,Pratviel, G.,Meunier, B.,Holland, L.,Lippert, B. (2007) 'Spontaneous reduction of mixed 2,2?-bipyridine/methylamine/chloro complexes of PtIV in water in the presence of light is accompanied by complex isomerization, loss of methylamine, and formation of a strong oxidant, presumably HOCl'. Chemistry - A European Journal, 13 (14) [Details]
(2006) 'Interactions of molybdocene dichloride with histidine- and methionine-containing peptides'
Erxleben,A.,Kottmann, J. (2006) 'Interactions of molybdocene dichloride with histidine- and methionine-containing peptides'. Inorganica Chimica Acta, 359 (1) [Details]
(2006) 'Reaction behavior of molybdocene dichloride towards ribonucleosides and ribonucleoside monophosphates: Rare example of sugar coordination'
Erxleben,A.,Yovkova, L. (2006) 'Reaction behavior of molybdocene dichloride towards ribonucleosides and ribonucleoside monophosphates: Rare example of sugar coordination'. Inorganica Chimica Acta, 359 (8) [Details]
(2005) 'Synthesis and spectroscopy of diethyl (pyridinylmethyl)phosphates and their palladium (II) complexes: X-ray crystal structures of Pd(II) complexes'
Kalinowska,U.,Checinska, L.,Malecka, M.,Erxleben, A.,Lippert, B.,Ochocki,J. (2005) 'Synthesis and spectroscopy of diethyl (pyridinylmethyl)phosphates and their palladium (II) complexes: X-ray crystal structures of Pd(II) complexes'. Inorganica Chimica Acta, 358 (8) [Details]
(2005) 'Interaction of molybdocene dichloride with cysteine-containing peptides: Coordination, regioselective hydrolysis, and intramolecular aminolysis'
Erxleben,A. (2005) 'Interaction of molybdocene dichloride with cysteine-containing peptides: Coordination, regioselective hydrolysis, and intramolecular aminolysis'. Inorganic Chemistry, 44 (4) [Details]
(2004) 'Metal-mediated deamination of cytosine: Experiment and DFT calculations'
Sponer,J.E.,Miguel,P.J.S.,Rodriguez-Santiago,L.,Erxleben,A.,Krumm,M., Sodupe,M.,Sponer,J.,Lippert, B. (2004) 'Metal-mediated deamination of cytosine: Experiment and DFT calculations'. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 43 (40):5396-5399 [Details]
(2003) 'Structures and properties of Zn(II) coordination polymers'
Erxleben A. (2003) 'Structures and properties of Zn(II) coordination polymers'. Coordination Chemistry Reviews, 246 (1-2) [Details]
(2003) 'Inter- and intra-molecular condensation patterns of (en)PdII with trans-[a2PtL2]2+ (a = am(m)ine, L = 2-aminopyridine): PtPd3 and Pt2Pd4 species with multiple amide bridges. Unexpected trapping of a pair of nitrate ions by a Pt2Pd4 double cone'
Beck,B.,Schneider, A.,Freisinger, E.,Holthenrich, D.,Erxleben, A.,Albinati, A.,Zangrando, E., Randaccio, L.,Lippert, B. (2003) 'Inter- and intra-molecular condensation patterns of (en)PdII with trans-[a2PtL2]2+ (a = am(m)ine, L = 2-aminopyridine): PtPd3 and Pt2Pd4 species with multiple amide bridges. Unexpected trapping of a pair of nitrate ions by a Pt2Pd4 double cone'. Dalton Transactions, 12 [Details]
(2003) 'Coordination polymers derived from silver salts and an aliphatic N,O ligand'
Erxleben,A. (2003) 'Coordination polymers derived from silver salts and an aliphatic N,O ligand'. Inorganica Chimica Acta, (348) [Details]
(2002) 'Silver co-ordination compounds with aliphatic nitriles containing amino nitrogen as H bond donor or additional metal binding site: formation of a ring, a chain, a polymeric sheet and a 3D polymeric channeled structure'
Erxleben,A. (2002) 'Silver co-ordination compounds with aliphatic nitriles containing amino nitrogen as H bond donor or additional metal binding site: formation of a ring, a chain, a polymeric sheet and a 3D polymeric channeled structure'. CrystEngComm, 4 :472-477 [Details]
(2002) 'Model of the most abundant DNA interstrand cross-link of Transplatin: X-ray structures of two modifications and H bonding behavior in the solid state and in solution of trans-[Pt(NH3)2(1-MeC-N3)(9-EtGH-N7)](ClO4) 2·nH2O (1-MeC=1-methylcytosine; 9-EtGH=9-ethylguanine)'
Erxleben,A.,Metzger,S.,Britten, J.F.,Lock,C.J.L.,Albinati, A.,Lippert, B. (2002) 'Model of the most abundant DNA interstrand cross-link of Transplatin: X-ray structures of two modifications and H bonding behavior in the solid state and in solution of trans-[Pt(NH3)2(1-MeC-N3)(9-EtGH-N7)](ClO4) 2·nH2O (1-MeC=1-methylcytosine; 9-EtGH=9-ethylguanine)'. Inorganica Chimica Acta, (339) [Details]
(2002) 'Association patterns of platinated purine nucleobases in metal-modified pairs and triples'
Roitzsch,M.,Rother, I.B.,Willermann, M.,Erxleben, A.,Costisella, B.,Lippert, B. (2002) 'Association patterns of platinated purine nucleobases in metal-modified pairs and triples'. Inorganic Chemistry, 23 (41) [Details]
(2002) 'Anion-dependent substitution of zinc by magnesium in mononuclear Schiff base complexes'
Hermann,J.,Schumacher, D.,Erxleben, A. (2002) 'Anion-dependent substitution of zinc by magnesium in mononuclear Schiff base complexes'. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, (9):2276-2280 [Details]
(2001) 'Synthesis and structure of a helical coordination polymer: {[Zn-2bdaip)mu-OH)OH)]NO3 center dot 2H2)O}infinity) Hbdaip=2,6-bis{N-[2-dimethylamino)ethyl]-iminomethyl}-4-methylpihenol)'
Erxleben,A. (2001) 'Synthesis and structure of a helical coordination polymer: {[Zn-2bdaip)mu-OH)OH)]NO3 center dot 2H2)O}infinity) Hbdaip=2,6-bis{N-[2-dimethylamino)ethyl]-iminomethyl}-4-methylpihenol)'. INORGANIC CHEMISTRY, 40 (2):412-414 [Details]
(2001) 'Magnesium versus zinc coordination to multidentate Schiff base ligands'
Erxleben, A, Schumacher, D. (2001) 'Magnesium versus zinc coordination to multidentate Schiff base ligands'. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, (12):3039-3046 [Details]
(2001) 'Mono- and dinuclear zinc complexes derived from unsymmetric binucleating ligands: Synthesis, characterization, and formation of tetranuclear arrays'
Erxleben,A. (2001) 'Mono- and dinuclear zinc complexes derived from unsymmetric binucleating ligands: Synthesis, characterization, and formation of tetranuclear arrays'. Inorganic Chemistry, 2 (40) [Details]
(2001) 'Magnesium coordination to biomimetic ligands'
Erxleben, A.,Schumacher, D.,Hermann, J. (2001) 'Magnesium coordination to biomimetic ligands'. JOURNAL OF INORGANIC BIOCHEMISTRY, 86 (1) [Details]
(2001) 'Synthesis and structure of {[Ag(SalGly)]·0.33H2O}n: An infinite double helical coordination polymer'
Erxleben,A. (2001) 'Synthesis and structure of {[Ag(SalGly)]·0.33H2O}n: An infinite double helical coordination polymer'. Inorganic Chemistry, 12 (40) [Details]
(2000) 'trans-a2)PtII)- a = NH3, CH3NH2) modified purine base pairs and triples: Hydrogen bonding between self-complementary pairs and triples and heterometal Ag+) coordination leading to a 1 D helix'
Rother,I.B.,Freisinger, E.,Erxleben, A.,Lippert, B. (2000) 'trans-a2)PtII)- a = NH3, CH3NH2) modified purine base pairs and triples: Hydrogen bonding between self-complementary pairs and triples and heterometal Ag+) coordination leading to a 1 D helix'. INORGANICA CHIMICA ACTA, 300 :339-352 [Details]
(2000) 'Di- and poly-nuclear zincII) Schiff base complexes: synthesis, structural studies and reaction with an alpha-amino acid'
Erxleben, A, Hermann, J. (2000) 'Di- and poly-nuclear zincII) Schiff base complexes: synthesis, structural studies and reaction with an alpha-amino acid'. DALTON TRANSACTIONS, (4):569-575 [Details]
(2000) 'Synthesis, crystal structure and solution behavior of a novel tetranuclear Zn(II) Schiff base complex'
Hermann J., Erxleben, A. (2000) 'Synthesis, crystal structure and solution behavior of a novel tetranuclear Zn(II) Schiff base complex'. Inorganica Chimica Acta, 1 (304) [Details]
(2000) 'Di- and poly-nuclear zinc(ii) Schiff base complexes: Synthesis, structural studies and reaction with an ?-amino acid ester'
Erxleben,A., Hermann,J. (2000) 'Di- and poly-nuclear zinc(ii) Schiff base complexes: Synthesis, structural studies and reaction with an ?-amino acid ester'. Journal of the Chemical Society, Dalton Transactions, 4 [Details]
(1999) 'Erratum: Bis(purine) complexes of trans-a2Pt(II): Preparation and X- ray structures of bis(9-methyladenine) and mixed 9-methyladenine, 9- methylguanine complexes and chemistry relevant to metal-modified nucleobase triples and quartets (Journal of the American Chemical Society (1996) 118 (4124-4132))'
Schreiber, A.,Luth, M.S.,Erxleben, A.,Fusch, E.C.,Lippert, B. (1999) 'Erratum: Bis(purine) complexes of trans-a2Pt(II): Preparation and X- ray structures of bis(9-methyladenine) and mixed 9-methyladenine, 9- methylguanine complexes and chemistry relevant to metal-modified nucleobase triples and quartets (Journal of the American Chemical Society (1996) 118 (4124-4132))'. Journal of the American Chemical Society, 121 (13) [Details]
(1998) 'Bispurine) complexes of trans-a2)PtII): Preparation and X-ray structures of bis9-methyladenine) and mixed 9-methyladenine, 9-methylguanine complexes and chemistry relevant to Interactions between [AuX4]-) X = Cl, CN) and cytosine and guanine model nucleobases: salt formation with hemi-) protonated bases, coordination, and oxidative degradation of guanine'
Schimanski,A.,Freisinger, E.,Erxleben, A.,Lippert, B. (1998) 'Bispurine) complexes of trans-a2)PtII): Preparation and X-ray structures of bis9-methyladenine) and mixed 9-methyladenine, 9-methylguanine complexes and chemistry relevant to Interactions between [AuX4]-) X = Cl, CN) and cytosine and guanine model nucleobases: salt formation with hemi-) protonated bases, coordination, and oxidative degradation of guanine'. INORGANICA CHIMICA ACTA, 283 (1):223-232 [Details]
(1998) 'Interactions between [AuX4]-(X = Cl, CN) and cytosine and guanine model nucleobases: Salt formation with (hemi-) protonated bases, coordination, and oxidative degradation of guanine'
Schimanski,A., Freisinger,E., Erxleben, A.,Lippert, B. (1998) 'Interactions between [AuX4]-(X = Cl, CN) and cytosine and guanine model nucleobases: Salt formation with (hemi-) protonated bases, coordination, and oxidative degradation of guanine'. Inorganica Chimica Acta, 283 (1) [Details]
(1997) 'Metal-modified nucleobase pairs involving 7,9-dimethylguanine: trans- a2Pt(II) analogues (a = NH3 or CH3NH2) of Watson-Crick GC and homo GG pairs'
Metzger,S.,Erxleben, A.,Lippert, B. (1997) 'Metal-modified nucleobase pairs involving 7,9-dimethylguanine: trans- a2Pt(II) analogues (a = NH3 or CH3NH2) of Watson-Crick GC and homo GG pairs'. Journal of Biological Inorganic Chemistry, 2 (2) [Details]
(1997) 'Synthesis and Spectroscopy of Phosphonate Derivatives of Uracil and Thymine. X-Ray Crystal Structure of Diethyl 6-Uracilmethylphosphonate'
Ochocki,J.,Erxleben, A.,Lippert,B. (1997) 'Synthesis and Spectroscopy of Phosphonate Derivatives of Uracil and Thymine. X-Ray Crystal Structure of Diethyl 6-Uracilmethylphosphonate'. Journal of Heterocyclic Chemistry, 34 (4) [Details]
(1996) 'First examples of polymeric mixed-metal (Pt-Ag) complexes containing single acetamidate bridges: cis-[(NH3)2Pt(NHCOMe)2Ag]NO 3·4H2O and trans-[(NH3)2Pt(NHCOMe)2Ag]NO 3·1.5H2O'
Erxleben,A.,Lippert, B. (1996) 'First examples of polymeric mixed-metal (Pt-Ag) complexes containing single acetamidate bridges: cis-[(NH3)2Pt(NHCOMe)2Ag]NO 3·4H2O and trans-[(NH3)2Pt(NHCOMe)2Ag]NO 3·1.5H2O'. Journal of the Chemical Society - Dalton Transactions, (11) [Details]
(1996) 'The Uracil C(5) Position as a Metal Binding Site: Solution and X-ray Crystal Structure Studies of PtII and HgII Compounds'
Hopp,M.,Erxleben,A.,Rombeck, I.,Lippert,B. (1996) 'The Uracil C(5) Position as a Metal Binding Site: Solution and X-ray Crystal Structure Studies of PtII and HgII Compounds'. Inorganic Chemistry, 35 (2) [Details]
(1996) 'Ternary complex of cisplatin with glycine and 1-methyluracil: Cis-[(NH3)2Pt(glyH-N)(1-MeU-N3)]ClO 4·H2O'
Hohmann,S.,Erxleben,A.,Wienkotter, T.,Lippert, B. (1996) 'Ternary complex of cisplatin with glycine and 1-methyluracil: Cis-[(NH3)2Pt(glyH-N)(1-MeU-N3)]ClO 4·H2O'. Inorganica Chimica Acta, 247 (1) [Details]
(1996) 'Heteronuclear ?-1-methylcytosinato-N3,N4 complexes containing very short Pt?Cu dative bonds'
Fusch,G.,Fusch, E.C.,Erxleben, A.,Huttermann, J.,Scholl H.-J.,Lippert, B. (1996) 'Heteronuclear ?-1-methylcytosinato-N3,N4 complexes containing very short Pt?Cu dative bonds'. Inorganica Chimica Acta, 252 (1-2) [Details]
(1996) 'Bispurine) complexes of trans-a2)PtII): Preparation and X-ray structures of bis9-methyladenine) and mixed 9-methyladenine, 9-methylguanine complexes and chemistry relevant to metal-modified nucleobase triples and quartets'
Schreiber,A.,Luth, M.S.,Erxleben, A.,Fusch, E.C.,Lippert, B. (1996) 'Bispurine) complexes of trans-a2)PtII): Preparation and X-ray structures of bis9-methyladenine) and mixed 9-methyladenine, 9-methylguanine complexes and chemistry relevant to metal-modified nucleobase triples and quartets'. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 118 (17):4124-4132 [Details]
(1996) 'Heteronuclear Pt-Pd, Pt2Cu and Pt2Ni complexes with bridging acetamidate: Crystal structures and spectroscopic studies'
Erxleben,A.,Albinati, A.,Lippert, B. (1996) 'Heteronuclear Pt-Pd, Pt2Cu and Pt2Ni complexes with bridging acetamidate: Crystal structures and spectroscopic studies'. Journal of the Chemical Society - Dalton Transactions, (9) [Details]
(1995) 'HETERONUCLEAR NUCLEOBASE COMPLEXES AS TOOLS FOR THE ISOLATION OF THE MINOR ROTAMER OF THE PARENT COMPOUND - SYNTHESIS AND CRYSTAL-STRUCTURE DETERMINATION OF HEAD-HEAD AND HEAD-TAIL FORMS OF TRANS-[CH3NH2)2)PT1-MEC-N3)2)]2+) 1-MEC=1-METHYLCYTOSINE)'
HOLTHENRICH,D.,SOVAGO, I.,FUSCH, G.,ERXLEBEN, A.,FUSCH, EC.,ROMBECK, I.,LIPPERT, B. (1995) 'HETERONUCLEAR NUCLEOBASE COMPLEXES AS TOOLS FOR THE ISOLATION OF THE MINOR ROTAMER OF THE PARENT COMPOUND - SYNTHESIS AND CRYSTAL-STRUCTURE DETERMINATION OF HEAD-HEAD AND HEAD-TAIL FORMS OF TRANS-[CH3NH2)2)PT1-MEC-N3)2)]2+) 1-MEC=1-METHYLCYTOSINE)'. ZEITSCHRIFT FEUR NATURFORSCH, 50 (11):1767-1775 [Details]
(1994) '[(en)Pt(uracilate)]44+: A metal analogue of calix[4]arene. Similarities and differences with classical calix[4]arenes'
Rauter,H.,Hillgeris, E.C.,Erxleben, A.,Lippert, B. (1994) '[(en)Pt(uracilate)]44+: A metal analogue of calix[4]arene. Similarities and differences with classical calix[4]arenes'. Journal of the American Chemical Society, 116 (2) [Details]
(1994) 'CONVERSION OF ACETONITRILE INTO ACETAMIDE IN THE COORDINATION SPHERES OF CIS-MII)AMINE)2) AND TRANS-MII)AMINE)2) M=PT OR PD) - SOLUTION AND CRYSTAL STRUCTURAL STUDIES'
ERXLEBEN,A.,MUTIKAINEN, I.,LIPPERT, B. (1994) 'CONVERSION OF ACETONITRILE INTO ACETAMIDE IN THE COORDINATION SPHERES OF CIS-MII)AMINE)2) AND TRANS-MII)AMINE)2) M=PT OR PD) - SOLUTION AND CRYSTAL STRUCTURAL STUDIES'. DALTON TRANSACTIONS, (24):3667-3675 [Details]