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About NUI Galway
About NUI Galway
Since 1845, NUI Galway has been sharing the highest quality teaching and research with Ireland and the world. Find out what makes our University so special – from our distinguished history to the latest news and campus developments.
Colleges & Schools
Colleges & Schools
NUI Galway has earned international recognition as a research-led university with a commitment to top quality teaching across a rang of key areas of expertise.
- Research Office
Business & Industry
Guiding Breakthrough Research at NUI Galway
We explore and facilitate commercial opportunities for the research community at NUI Galway, as well as facilitating industry partnership.
- Alumni, Friends & Supporters
At NUI Galway, we believe that the best learning takes place when you apply what you learn in a real world context. That's why many of our courses include work placements or community projects.
Prof Brian McStay BA, PhD
Peer Reviewed Journals
|LaVolpe, A., Taggart, M.,McStay, B., and Bird, A.P. (1983) 'DNaseI Hypersensitive sites at promoter like sequences in the spacer of X.laevis and X. Borealis'. Nucl. Acids Res, 11 :5361-5380. [Details]|
|McStay, B. and Bird, A.P. (1983) 'The origin of the rRNA precursor from X.borealis analysed in vivo and in vitro'. Nucl. Acids Res, 11 :8167-8181. [Details]|
|McStay, B. and Reeder, R.H. (1986) 'A termination site for Xenopus RNA polymerase I also acts as an element of an adjacent promoter'. Cell, 47 :913-920. [Details]|
|Reeder, R.H., Pennock, D., McStay, B., Roan, J., Tolentino, E. and Walker, P. (1987) 'Linker scanner mutagenesis of the Xenopus laevis ribosomal gene promoter'. Nucl. Acids Res, 15 :7429-7441. [Details]|
|Reeder, R.H., Labhart, P.L. and Mc Stay, B. (1987) 'Processing and termination of RNA polymerase I transcripts'. BioEssays, 6 :108-112. [Details]|
|Pikaard, C.S., McStay, B.M., Schultz, M.C., Bell, S.P. and Reeder, R.H. (1989) 'The Xenopus ribosomal gene enhancers bind an essential polymerase I transcription factor'. Genes and Development, 3 :1779-1788. [Details]|
|McStay, B. and Reeder, R.H. (1990) 'An RNA polymerase I termination site can stimulate the adjacent ribosomal gene promoter by two distinct mechanisms in Xenopus laevis'. Genes and Devolpment, 4 :1240-1252. [Details]|
|McStay, B. and Reeder, R.H. (1990) 'A DNA-binding protein is required for termination of transcription in Xenopus laevis'. Mol.Cell.Biol, 10 :2793-2800. [Details]|
|McStay, B., Frazier, M. W. and Reeder, R.H. (1991) 'xUBF contains a novel dimerization domain essential for RNA polymerase I transcription'. Genes and Development, 5 :1957-1968. [Details]|
|McStay, B., Hu C. H., Pikaard, C.S. and Reeder, R.H. (1991) 'xUBF and Rib I are both required for formation of a stable RNA polymerase I promoterv complex in X.laevis'. EMBO journal, 10 :2297-2303. [Details]|
|Palmer, T., Miller, A.D., Reeder, R.H. and McStay, B.M. (1993) 'Efficient expression of a protein coding gene under the control of an RNA polymerase I promoter'. Nucleic Acids Res, 21 :3451-3457. [Details]|
|Hu,C.H., McStay B.M. and Reeder, R.H. (1994) 'xUBF, an RNA polymerase I transcription factor, crosslinks DNA'. Mol. Cell. Biol, 14 :2871-2882. [Details]|
|Cairns, C. and McStay, B. (1995) 'HMG box 4 is the principal determinant of species psecificity in the RNA polymerase I transcription factor UBF'. Nuc. Acids Res, 22 :4583-4590. [Details]|
|Cairns, C. and McStay, B. (1995) 'Identification and cDNA cloning of a xenopus nucleolar phosphoprotein xNopp180, that is the homolog of the rat nucleolar protein Nopp140'. J. Cell Science, 108 :3339-3347. [Details]|
|Reeder, R.H., Pikaard, C.S. and McStay, B. (1995) 'UBF an architectural element for RNA polymerase I promoters'. Nucleic Acids and Molecular Biology, 9 :251-263. [Details]|
|Bodeker, M., Cairns,C and McStay,B. (1996) 'Upstream Binding Factor stabilizes Rib1, the TATA-binding-protein-containing RNA Polymerase I transcription factor, by multiple protein interactions in a DNA-independent manner'. Mol. Cell. Biol, 16 :5572-5578. [Details]|
|McStay, B., Sullivan, G.J. and Cairns C. (1997) 'The Xenopus RNA polymerase I transcription factor, UBF, has a role in transcriptional enhancement distinct from that at the promoter'. EMBO Journal, 16 :396-405. [Details]|
|Bell, P., Mais, C., McStay, B. and Scheer, U. (1997) 'Association of the nucleolar transcription factor UBF with the transcriptionally inactive rRNA genes of pronuclei and early Xenopus embryos'. J.Cell Science, 110 :2053-2063. [Details]|
|Sullivan, G.J. Bridger, J.M., Cuthbert, A.P., Newbold, R.. Bickmore, W.A. and McStay. (2001) 'Human acrocentric chromosomes with transcriptionally silent nucleolar organiser regions can associate with heterologous nucleoli'. EMBO Journal, 20 :2867-2877. [Details]|
|Audrey C. O'Sullivan, Gareth J. Sullivan and Brian McStay (2002) 'UBF binding in vivo is not restricted to regulatory sequences within the vertebrate rDNA repeat'. Mol.Cell.Bio, 22 :657-668. [Details]|
|Mais C, McStay B, Scheer U. (2002) 'On the formation of amplified nucleoli during early Xenopus oogenesis'. J Struct Biol, 140 :214-226. [Details]|
|McStay B, Paule M, Schultz MC, Willis I, Pikaard CS (2002) 'Oddpols united: new insights into transcription by RNA polymerases I and III'. Gene Expr, 10 :263-269. [Details]|
|Prieto, J.L. and McStay B (2005) 'Nucleolar biogenesis; the first small steps'. Biochemical Society Transactions, 33 (6):1441-1443. [Details]|
|Mais, C., Wright, J.E., Prieto, J.L., Raggett, S.L. and McStay B. (2005) 'UBF Binding Site Arrays Form Pseudo-NORs and Sequester the RNA Pol I Transcription Machinery'. Genes and Development, 19 :50-64. [Details]|
|F. J. Lawrence, B. McStay and D. A. Matthews (2006) 'Nucleolar protein Upstream Binding Factor is sequestered into adenovirus DNA replication centres during infection without affecting RNA polymerase I location or ablating rRNA synthesis'. J. Cell. Sci, 119 :2621-2631. [Details]|
|McStay, B. (2006) 'Nucleolar dominance: a model for rRNA gene silencing'. Genes and Development, 20 :1207-1214. [Details]|
|Wright, J.E., Mais, C., Prieto, J.L. and McStay B (2006) 'A role for UBF in organising ribosomal gene chromatin'. Biochem Soc Symp, 73 :77-84. [Details]|
|Prieto, J.L. and McStay B (2007) 'Factors linking transcription and processing of pre-rRNA in human cells are recruited to nucleolar organiser region chromatin independent of transcription'. Genes and Development, 21 :2041-2054. [Details]|
|Prieto JL, McStay B. (2008) 'Pseudo-NORs: a novel model for studying nucleoli'. BBA Molecular Cell Research, 1783 :2116-2123. [Details]|
|McStay B, Grummt I (2008) 'The epigenetic regulation of ribosomal gene expression'. Annu Rev Cell Dev Biol, 24 :131-157. [Details]|
|Grob A., Roussel P., Wright J.E., McStay B., Hernandez-Verdun D. and Sirri V. (2008) 'Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis'. J.Cell Sci, . [Details]|
|Turner AJ, Knox AA, Prieto JL, McStay B, Watkins NJ (2009) 'A novel SSU processome assembly intermediate that contains the U3 snoRNP, nucleolin, RRP5 and DBP4'. Mol Cell Biol, 29 (11):3007-3017. [Details]|