Dr. Alan Ryder

BSc., PhD

Contact Details

Principal Investigator
Nanoscale Biophotonics
C213
Physical Chemistry section
School of Chemistry

T: +35391492943
F: +35391495576
E: alan.ryder@nuigalway.ie
W: www.nuigalway.ie/nanoscale
Senior Lecturer
School of Chemistry
Room 213
Arts/Science Building
NUI Galway

T: Ext. 2943
E: alan.ryder@nuigalway.ie
 
researcher

Biography

Dr. Alan G. Ryder is a Senior lecturer in the School of Chemistry at the National University of Ireland-Galway.  He obtained a B.Sc.(1.1) in Chemistry (1989) and Ph.D. Inorganic chemistry (1994) from NUI-Galway.  After a stint as a postdoctoral researcher in UCC, he rejoined NUI-Galway in 1997 to work on developing quantitative Raman spectroscopic methods for measuring illicit narcotic concentrations.  In 1998, awarded a Forbairt post-doctoral fellowship, he started to develop time-resolved fluorescence methods for petroleum analysis.  During this time, he began building up the nucleus of the Nanoscale Biophotonics Laboratory (NBL) and in 2003, the NBL was formally established, with a grant from Science Foundation Ireland.  The group is focused on the use of optical spectroscopy for life and physical science applications, with a strong focus on pharmaceutical applications.   Dr. Ryder has two core research areas: Process Analytical Technologies (PAT) and Advanced Fluorescence spectroscopy for biomedical and environmental applications.
 
In the PAT domain projects include the use of Raman and/or fluorescence spectroscopy with multivariate analysis methods for the qualitative and qualitative analysis of materials with particular focus on materials used in large and small molecule Active Pharmaceutical Ingredient (API) manufacture.  In 2005 he began work on the Centre for Bioanalytical Sciences (CBAS) project with Bristol-Myers Squibb developing novel spectroscopic and chemometric methods for the biopharmaceutical manufacturing sector. This research is developing an integrated analytical platform technology (multi-dimensional fluorescence, chemometrics, and experimental design) for the quantitative, rapid analysis of complex biogenic materials.  This ranges from raw materials, to cell culture media, and  to protein solutions.   We collaborate with several biologics manufacturers on developing novel analytical platforms. Past and present industrial collaborations include:  Bristol-Myers Squibb, Janssen-Biologics, Merck, Kaiser Optical Systems Inc., and Agilent. 

In the fluorescence domain, specific projects involve the use of advanced fluorescence spectroscopy and microscopy for the analysis of protein adsorption on surfaces, petroleum fluids, biomedical polymers, and fluorophore photophysics.  We also use fluorescence spectroscopy combined with advanced chemometrics for the study of complex biogenic materials.

To date, we have secured some 10M+ euro in research funding of which 2.8 M euro has been obtained from industrial sources.
He has authored more than 80 publications, generated 3 patents (2 granted, one licensed), and supervised 13 Ph.D. & 4 M.Sc. students to completion. 

Research Interests

My research can be divided into two core areas, Analytical Sciences and Photonics.  In the analytical sciences side we aim to develop new analytical methods for a wide variety of problems from biopharmaceutical manufacturing to oil exploration.  In the photonics research we focus on more fundamental studies of molecules and materials, and also on the building/modification of optical instrumentation.  In the long-term the photonics research feeds into the analytical research in terms of instrumentation and new measurement methodologies.  All of the research is a combination of chemistry, physics and mathematics.   Analytical Sciences:  The underlying goal is to produce novel analytical methods for the rapid, minimally invasive and inexpensive analysis of complex samples.  This covers everything from illicit narcotics, to cell culture media and on to crude petroleum oils.  The most important active projects at the moment are:
  • Biopharmaceutical analysis:  Development of novel rapid, quantitative analytical methods for use in the BioPharma sector.  The primary methods to be employed are vibrational spectroscopy, fluorescence spectroscopy, and chemometrics.  This was initially part of a collaborative project, the Centre for BioAnalytical Science (CBAS), with Bristol Myers-Squibb (2005-09) and has now been extended to projects with Janssen-Biologics (2010-2015), Schering-Plough/Merck (2011-12), and Kaiser Optical Systems Inc. (2011-onwards).  These projects involves the study of all aspects of the biopharma production process from raw staring materials, to media, to process samples, and up to finished product.  The key spectroscopic techniques employed are Raman spectroscopy and Multi-dimensional fluorescence.  A more recent collaboration with Kaiser Optical Systems Inc. is focusing on implementing Raman methods for low-content analysis and the characterization of the complex materials used in biopharmaceutical manufacturing and Real-Time-Release testing of small molecule APIs.

  • Biomaterials:  This encompasses two different yet interlinked projects.  First, the development of fluorescence based methods for measuring surface and bulk polarity of polymers, which is also linked with studies to develop method for measuring drug elution rates from biomedical polymers (in conjunction with Y. Rotchev (NUIG), C. Elvira (Madrid), A Gorelov (UCD), and A. Klymchenko (Strasbourg)).  The second core project is the development of ultra-sensitive methods for measuring the deposition and the conformation of proteins on surfaces.  This project involves the use of advanced microscopy (TIRF) coupled with steady-state and time-resolved fluorescence spectroscopy. 

  • Spectroscopy and Chemometrics:  Development of quantitative methods of analysis for pharmaceutical, forensic, and law enforcement applications.  Development of novel chemometric and machine learning methods for the analysis of Raman spectroscopic data.  Study of materials and microscopic fluid inclusions by Raman analysis.   

  • Petroleum fluid and inclusions analysis:  Development of instrumentation and analysis methods for crude oil characterization and quantification.  Study of the fundamental processes governing petroleum fluorescence.  Study of petroleum bearing fluid inclusions. 
  Photonics:  This aspect of my research is a combination of fundamental research and instrumentation development and use.  It is in some ways closer to physics, but helps feed the analytical science research with new techniques and novel instrumentation
  • Triazine Photophysics: This collaboration with Dr. J. Stephens of NUI Maynooth, looks at the fundamental photophysics of this novel class of fluorophores.  These dual band emitters have unique emission properties and are accessible via a facile synthetic route.  The research involves steady-state and time-resolved methodologies.  In the long-term we hope that this new fluorophore class will have many applications in sensing and protein labelling.
  • Advanced Fluorescence Microscopy:   A second component of the research involves the application of advanced fluorescence microscopy techniques to measuring dynamic biological and chemical processes at surfaces, and in living cells.  The involves the use of methods such as Fluorescence Lifetime Imaging Microscopy (FLIM), Fluorescence Correlation Spectroscopy (FCS), Fluorescence Cross-Correlation Spectroscopy (FCCS), and Total Internal Reflection Fluorescence Microscopy (TIRFM).  This aspect of my research programme encompasses a wide range of collaborators (Anatomy, Biochemistry, Earth & Ocean Sciences etc.).
  • Plasmonics:  Developing novel, highly sensitive, spectroscopic methods, for applications in the clinical and life sciences by the utilisation of the Metal Enhanced Fluorescence (MEF) and Surface Enhanced Raman Scattering (SERS) effects.   Specific aspects of the project involve the development of novel methods for fabricating nano-structured MEF substrates and the study of the physical and chemical factors influencing the emission behavior of fluorophores on surfaces.  More recently we have studied SERS of complex mixtures.
  In addition, to the core research projects outlined above, there are several concurrent interdisciplinary research projects with a variety of disparate departments in NUI-Galway and other Irish third level institutions. 

Research Projects

  Project Start Date End Date
Anisotropy Reseolved Multidimensional Emission Spectroscopy (ARMES) for quantification of protein aggregation 01-OCT-15 30-SEP-18
The Application of Advanced Raman Spectroscopies to the Quantitative Analysis of Complex Biogenic Materials 01-OCT-15 30-SEP-17
CAPES Camila Van Zanten Coura - Alan Ryder 01-SEP-15 31-AUG-19
Advanced Analytics for Biological Therapeutic Manufacture (AA-BTM) 28-AUG-15 31-JUL-20
EFFECTIVE ANALYTICAL METHODOLOGIES FOR JANSSEN MATERIALS ALAN RYDER 01-MAR-14 31-DEC-16
SYNTHESIS & SOLID STATE PHARMACEUTICAL CENTRE(SSPC) A RYDER 01-JUN-13 31-MAY-19
SYNTHESIS & SOLID STATE PHARMACEUTICAL CENTRE(SSPC) INDUSTRY ACCOUNT A RYDER 01-JUN-13 31-MAY-19
RAPID SPECTRSCOPIC METHODS THE SEQUEL ALAN RYDER 01-FEB-13 31-JAN-16
ACTIVE PHARMACEUTICAL INGREDIENT API REAL TIEM RELEASE PAT ALAN RYDER TC AWARD 01-NOV-12 28-FEB-14
IRC EMBARK P ZARSKI ALAN RYDER 01-OCT-12 30-SEP-16
IRC EMBARK RADU CONSTANTIN GROZA ALAN RYDER 01-OCT-12 30-SEP-16
IRC EMBARK INITIATIVE MICHELLE KYNE ALAN RYDER 01-OCT-12 30-SEP-16
RAPID SPECTROSCOPIC METHODS FOR RAW MATERIALS, ALAN RYDER 01-JUL-11 30-JUN-14
NIBRT JANSSEN ALAN RYDER 01-SEP-10 31-DEC-13
EMBARK INITIATIVE AMANDINE CALVET RS2000666- ALAN RYDER 01-OCT-09 30-SEP-13
Total Internal Reflection Fluorescence Microscopy 01-DEC-07 30-MAY-08
NAT BIOPHOTO & IMAGING PLATFORM RYDER DOCKERY 01-OCT-07 30-SEP-15
SPECTROSCOPY RESEARCH ACCOUNT A RYDER 10-SEP-07 31-DEC-15
QUANTITATIVE NON CONTACT POLYMOR MEARSUREMENTS 01-AUG-07 31-JAN-11
OIP 2007 0.5 FTE ADMIN SUPPORT A RYDER 01-JAN-07 31-DEC-07
SFI Petrology,Fluorescence & Microther A Ryder 05-JUN-06 30-SEP-06
SFI PETROLEUM OILS & HYDROCARBON ALAN RYDER 31-JUL-05 31-JAN-09
pH SENSOR CLINICAL USE 02 IN.1 M231 STAR05 RYDER 01-JUN-05 20-OCT-05
SFI UREKA SUPPLEMENT 02 IN3I231ur05.1 A RYDER 06-JUN-05 22-AUG-05
SFI UREKA SUPP. 02 I.1 I231ur05.2 ALAN RYDER 06-JUN-05 12-DEC-05
SFI 02 IN 1 M231NANOSCALE BIOPHOTONICS SUPP EQT 16-NOV-04 31-JUL-05
SFI STAR AWARD 01 IN1 M231STAR ALAN RYDER 01-JUL-04 31-JAN-05
SFI EUREKA SUPPLEMENT DR. ALAN RYDER 01-JUL-04 30-JUN-05
SFI 02 IN 1 M231NANOSCALE BIOPHOTONICS 01-AUG-03 31-JAN-08

Contract Researchers

  Researcher Name Project Role Funding Body
Dr. Boyan Li Current: Synthesis & Solid-State Pharmaceutical Centre. (2006-present):  Works on analytical method development.  Originally employed by Bristol Myers Squibb (2006-09) as part of their commitment to the CBAS project. Then worked on various industrially funded bio-analytical research projects. Form 2014 onwards he has been working on SSPC related research. Science Foundation Ireland (SFI)
Dr. Kevin Buckley IRC Postdoctoral fellowship. IRC postdoctoral fellow researching the use of SORS for biopharma applications. Irish Research Council (IRC)
Dr. V. Murphy Janssen Media analysis projects Working on media and protein characterisation projects. Responsibilities include sample and laboratory management, data collection, data analysis, student project training & supervision, and report writing. Industrial Contracts
Dr. D. Togashi “Nanoscale Biophotonics: Novel Approaches to Ultra-Sensitive and High Accuracy Fluorescence Techniques.” (2004-11).  Dr. Togashi was developing fluorescence-based methods for measuring the interaction of proteins with surfaces, and the structural changes of proteins in solution. He was funded first by SFI (SFI Research Grants Scheme for Investigators (02/IN.1/M231)) and then by HEA PRTLI-IV. Other Government
Dr. R. Rajko CBAS collaboration with BMS Developing novel chemometric based approaches for the quantitative and qualitative analysis of complex mixtures by vibrational and X-Ray fluorescence spectroscopies. Other
B. Kissane Merck, NIBRT/J&J media analysis projects. Worked as a research assistant responsible for sample & laboratory management, report writing, and the collection of spectroscopic data. Industrial Contracts
Dr. M. Phelan “Hazard-IQ: Intelligent Quantification of Raman Spectral Data for Hazardous and Illicit Substances” Enterprise Ireland Technology Development Grant (TD/03/212). Hazard-IQ project, now at Henkl Dublin doing industrial research. Enterprise Ireland (EI)
Dr. C. Morris (2012-14):  Worked on various industrially funded bio-analytical research projects (Merck, Janssen-Biologics).
Mr. Yannick Casamayou Boucau Raman analysis of APIs and cell culture media. Research assistant. Other
Dr. N.S. Sirimuthu CBAS collaboration with BMS Developing novel spectroscopic analysis methods for the quantitative and qualitative analysis of complex mixtures.  Now in Glasgow. Other
Dr. P. Fournet “Nanoscale Biophotonics: Novel Approaches to Ultra-Sensitive and High Accuracy Fluorescence Techniques.” (2004-06):  Novel substrates for Metal Enhanced Fluorescence and also working on making and characterising thin films made from the soluble metal oxides. Science Foundation Ireland (SFI)
Dr. P. Ryan CBAS collaboration with BMS Developing novel spectroscopic analysis methods for the quantitative and qualitative analysis of complex mixtures.  Now in Helsinki. Other
Dr. M. Leger “Hazard-IQ: Intelligent Quantification of Raman Spectral Data for Hazardous and Illicit Substances” Enterprise Ireland Technology Development Grant (TD/03/212). Chemometric based methods for the quantitative and qualitative analysis of illicit narcotics and hazardous materials. Enterprise Ireland (EI)
Dr. B.H. Ray CBAS collaboration with BMS   CBAS project, developing novel spectroscopic methods for the analysis of complex biological based feedstocks for the biopharmaceutical industry. Other
Dr. N. Blamey “Time-resolved fluorescence spectroscopic analysis of petroleum oils and hydrocarbon bearing fluid inclusions.” SFI Research Frontiers Programme, (05/RFP/GEO0002), Analysis of fluid inclusions using time-resolved fluorescence spectroscopy as part of the ongoing collaboration between A.R. and M. Feely.  Now at New Mexico Tech Science Foundation Ireland (SFI)
Dr. A. Calvet Active pharmaceutical ingredient API real time release PAT: Accurate Raman Analysis Methods for Real-Time-Release (ARAM-RTR), (2012-14):  lead postdoctoral researcher on the Enterprise Ireland/IDA funded Pharmaceutical Manufacturing Technology Centre. Enterprise Ireland (EI)
Dr. C. Moschner CBAS collaboration with BMS Developing novel spectroscopic analysis methods for the quantitative and qualitative analysis of complex mixtures.   Now at University of Kiel. Other

Peer Reviewed Journals

  Year Publication
(2016) 'Kernel principal component analysis residual diagnosis (KPCARD): an automated method to remove cosmic ray artefacts in Raman spectra'
Li, B., Calvet, A., Casamayou-Boucau, Y., Ryder, A.G. (2016) 'Kernel principal component analysis residual diagnosis (KPCARD): an automated method to remove cosmic ray artefacts in Raman spectra'. Analytica Chimica Acta, 913 :111-120 [DOI] [Details]
(2002) 'High pressure diamond and diamond-like carbon deposition using a microwave CAP reactor'
McConnell, ML,Dowling, DP,Pope, C,Donnelly, K,Ryder, AG,O'Connor, GM (2002) 'High pressure diamond and diamond-like carbon deposition using a microwave CAP reactor'. Diamond And Related Materials, 11 :1036-1040 [Details]
(2012) 'Ferromagnetic exchange in a twisted, oxime-bridged [Mn-2(III)] dimer'
Houton, E,Taylor, SM,Beedle, CC,Cano, J,Piligkos, S,Hill, S,Ryder, AG,Brechin, EK,Jones, LF (2012) 'Ferromagnetic exchange in a twisted, oxime-bridged [Mn-2(III)] dimer'. Dalton Transactions, 41 :8340-8347 [DOI] [Details]
(2016) 'Bench- and Pilot-Scale Continuous-Flow Hydrothermal Production of Barium Strontium Titanate Nanopowders'
Dunne, P.W.; Starkey, C.L.; Munn, A.S.; Tang, S.V.Y.; Luebben, O.; Shvets, I.; Ryder, A.G.; Casamayou-Boucau, Y.; Morrison, L.; Lester, E.H.; (2016) 'Bench- and Pilot-Scale Continuous-Flow Hydrothermal Production of Barium Strontium Titanate Nanopowders'. Chemical Engineering Journal, 289 :433-441 [DOI] [Details]
(2015) 'Low-content quantification in powders using Raman spectroscopy: a facile chemometric approach to sub 0.1% limits of detection'
Li, B.; Calvet, A.; Casamayou-Boucau, Y.; Morris, C.; Ryder, A.G. (2015) 'Low-content quantification in powders using Raman spectroscopy: a facile chemometric approach to sub 0.1% limits of detection'. Analytical Chemistry, 87 (6):3419-3428 [DOI] [Details]
(2015) 'Anisotropy resolved multidimensional emission spectroscopy (ARMES): A new tool for protein analysis'
Groza, RC; Li, BY; Ryder, AG; (2015) 'Anisotropy resolved multidimensional emission spectroscopy (ARMES): A new tool for protein analysis'. Analytica chimica acta, 886 :133-142 [DOI] [Details]
(2014) 'A fluorescence anisotropy method for measuring protein concentration in complex cell culture media'
Groza, RC; Calvet, A; Ryder, AG; (2014) 'A fluorescence anisotropy method for measuring protein concentration in complex cell culture media'. Analytica chimica acta, 821 :54-61 [DOI] [ARAN Link] [Details]
(2014) 'A rapid fluorescence based method for the quantitative analysis of cell culture media photo-degradation'
Calvet, A; Li, B; Ryder, A.G; (2014) 'A rapid fluorescence based method for the quantitative analysis of cell culture media photo-degradation'. Analytica chimica acta, 807 :111-119 [DOI] [ARAN Link] [Details]
(2014) 'Comprehensive, quantitative bioprocess productivity monitoring using fluorescence EEM spectroscopy and chemometrics'
Li, B; Shanahan, M; Calvet, A; Leister, KJ; Ryder, AG; (2014) 'Comprehensive, quantitative bioprocess productivity monitoring using fluorescence EEM spectroscopy and chemometrics'. Analyst, 139 :1661-1671 [DOI] [ARAN Link] [Details]
(2014) 'Monitoring cell culture media degradation using surface enhanced Raman scattering (SERS) spectroscopy'
Calvet, A; Ryder, AG; (2014) 'Monitoring cell culture media degradation using surface enhanced Raman scattering (SERS) spectroscopy'. Analytica chimica acta, 840 :58-67 [DOI] [ARAN Link] [Details]
(2014) 'A family of [Ni-8] cages templated by mu(6)-peroxide from dioxygen activation'
Perivolaris, A,Stoumpos, CC,Karpinska, J,Ryder, AG,Frost, JM,Mason, K,Prescimone, A,Slawin, AMZ,Kessler, VG,Mathieson, JS,Cronin, L,Brechin, EK,Papaefstathiou, GS (2014) 'A family of [Ni-8] cages templated by mu(6)-peroxide from dioxygen activation'. Inorganic Chemistry Frontiers, 1 :487-494 [DOI] [Details]
(2013) 'Performance Monitoring of a Mammalian Cell Based Bioprocess using Raman spectroscopy'
Li, B; Ray, B.H; Leister, K.J; Ryder, A.G; (2013) 'Performance Monitoring of a Mammalian Cell Based Bioprocess using Raman spectroscopy'. Analytica Chimica Acta, 796 :84-91 [DOI] [ARAN Link] [Details]
(2013) 'Solid-State Transformations of Sulfathiazole Polymorphs: The Effects of Milling and Humidity'
Hu, Y, Erxleben, A, Hodnett, BK, Li, BY, McArdle, P, Rasmuson, AC, Ryder, AG (2013) 'Solid-State Transformations of Sulfathiazole Polymorphs: The Effects of Milling and Humidity'. Crystal Growth & Design, 13 :3404-3413 [DOI] [Details]
(2013) 'Quantitative polymorph contaminant analysis in tablets using Raman and near infra-red spectroscopies'
Hennigan, MC; Ryder, AG; (2013) 'Quantitative polymorph contaminant analysis in tablets using Raman and near infra-red spectroscopies'. Journal Of Pharmaceutical And Biomedical Analysis, 72 :163-171 [DOI] [ARAN Link] [Details]
(2012) 'A comparative study of the use of powder X-ray diffraction, Raman and NIR spectroscopy for quantification of binary polymorphic mixtures of Piracetam'
D.M. Croker, M.C. Hennigan, A. Maher, Y. Hu, A.G. Ryder, B.K. Hodnett. (2012) 'A comparative study of the use of powder X-ray diffraction, Raman and NIR spectroscopy for quantification of binary polymorphic mixtures of Piracetam'. Journal Of Pharmaceutical And Biomedical Analysis, 63 :80-86 [DOI] [Details]
(2012) 'Rapid quantification of tryptophan and tyrosine in chemically defined cell culture media using fluorescence spectroscopy'
Calvet, A.; Li, BY.; Ryder, A.G.; (2012) 'Rapid quantification of tryptophan and tyrosine in chemically defined cell culture media using fluorescence spectroscopy'. Journal Of Pharmaceutical And Biomedical Analysis, 71 :89-98 [DOI] [ARAN Link] [Details]
(2012) 'Cell cycle-dependent mobility of Cdc45 in living cells determined by fluorescence correlation spectroscopy'
R. Broderick, S. Ramadurai, K. Toth, D. Togashi, A. G. Ryder, J. Langwoski, and H.P. Nasheuer. (2012) 'Cell cycle-dependent mobility of Cdc45 in living cells determined by fluorescence correlation spectroscopy'. Plos One, 7 (4):e35537-e35537 [DOI] [ARAN Link] [Details]
(2012) 'Using surface-enhanced Raman scattering (SERS) and fluorescence spectroscopy for screening yeast extracts, a complex component of cell culture media'
Li, BY; Sirimuthu, NMS; Ray, BH; Ryder, AG; (2012) 'Using surface-enhanced Raman scattering (SERS) and fluorescence spectroscopy for screening yeast extracts, a complex component of cell culture media'. Journal Of Raman Spectroscopy, 43 :1074-1082 [DOI] [ARAN Link] [Details]
(2012) 'Ferromagnetic exchange in a twisted, oxime-bridged [MnIII2] dimer'
Houton, E; Taylor, S. M; Beedle, C. C; Cano, J; Piligkos, S; Hill, S; Ryder, A. G; Brechin, E. K.; and Jones L. F; (2012) 'Ferromagnetic exchange in a twisted, oxime-bridged [MnIII2] dimer'. Dalton Transactions, 41 (27):8340-8347 [DOI] [Details]
(2011) 'Fluorescence EEM Spectroscopy for Rapid Identification and Quality Evaluation of Cell Culture Media Components'
B. Li, P.W. Ryan, M. Shanahan, K.J. Leister, and A.G. Ryder (2011) 'Fluorescence EEM Spectroscopy for Rapid Identification and Quality Evaluation of Cell Culture Media Components'. Applied Spectroscopy, 65 (11):1240-1249 [DOI] [ARAN Link] [Details]
(2011) 'Low temperature Fluorescence Study of Crude Petroleum Oils'
P. Owens and A.G. Ryder (2011) 'Low temperature Fluorescence Study of Crude Petroleum Oils'. Energy And Fuels, 25 (11):5022-5032 [DOI] [Details]
(2010) 'Study of water adsorption in Poly(N-isopropylacrylamide) thin films using fluorescence emission of 3-hydroxyflavone probes'
Morris, C. , Szczupak, B. , Klymchenko, A.S., Ryder, A.G. (2010) 'Study of water adsorption in Poly(N-isopropylacrylamide) thin films using fluorescence emission of 3-hydroxyflavone probes'. Macromolecules, 43 (22):9488-9494 [DOI] [Details]
(2010) 'Quantitative Analysis of Sulfathiazole Polymorphs in Ternary Mixtures by Attenuated Total Reflectance Infrared, Near-infrared and Raman Spectroscopy'
Hu, Y., Erxleben, A., Ryder, A.G., McArdle, P. (2010) 'Quantitative Analysis of Sulfathiazole Polymorphs in Ternary Mixtures by Attenuated Total Reflectance Infrared, Near-infrared and Raman Spectroscopy'. Journal of pharmaceutical and biomedical analysis, 53 (3):412-420 [DOI] [Details]
(2010) 'Monitoring Local Unfolding of Bovine Serum Albumin During Denaturation Using Steady-State and Time-Resolved Fluorescence Spectroscopy'
Togashi, D.M.; Ryder, A.G.;O'Shaughnessy, D.; (2010) 'Monitoring Local Unfolding of Bovine Serum Albumin During Denaturation Using Steady-State and Time-Resolved Fluorescence Spectroscopy'. Journal Of Fluorescence, 20 :441-452 [DOI] [ARAN Link] [Details]
(2010) 'Hydrocarbon migration in the Porcupine Basin, offshore Ireland: evidence from fluid inclusion studies'
Conliffe, J.; Blamey, N.F.; Feely, M.; Parnell, J.; Ryder, A.G.; (2010) 'Hydrocarbon migration in the Porcupine Basin, offshore Ireland: evidence from fluid inclusion studies'. Petroleum Geoscience, 16 :67-76 [DOI] [Details]
(2010) 'Qualitative Analysis Using Raman Spectroscopy and Chemometrics: A Comprehensive Model System for Narcotics Analysis'
O'Connell, ML,Ryder, AG,Leger, MN,Howley, T (2010) 'Qualitative Analysis Using Raman Spectroscopy and Chemometrics: A Comprehensive Model System for Narcotics Analysis'. Applied Spectroscopy, 64 :1109-1121 [Details]
(2010) 'Assessing protein-surface interactions with a series of multi-labeled BSA using fluorescence lifetime microscopy and Forster Energy Resonance Transfer'
Togashi, DM,Ryder, AG (2010) 'Assessing protein-surface interactions with a series of multi-labeled BSA using fluorescence lifetime microscopy and Forster Energy Resonance Transfer'. Biophysical Chemistry, 152 :55-64 [DOI] [Details]
(2010) 'Rapid Characterisation and Quality Control of Complex Cell Culture Media using Raman Spectroscopy and Chemometrics'
Li, B; Ryan, P.W; Ray, B.H; Leister, K.J; Sirimuthu, N.M.S; Ryder, A.G; (2010) 'Rapid Characterisation and Quality Control of Complex Cell Culture Media using Raman Spectroscopy and Chemometrics'. Biotechnology And Bioengineering, 107 (2):290-301 [DOI] [Details]
(2010) 'Prediction of Cell Culture Media performance using Fluorescence Spectroscopy'
P.W. Ryan, B. Li, M. Shanahan, K.J. Leister, and A.G. Ryder. (2010) 'Prediction of Cell Culture Media performance using Fluorescence Spectroscopy'. Analytical Chemistry, 82 (4):1311-1317 [DOI] [ARAN Link] [Details]
(2010) 'Corrigendum to Application of fluorescence lifetime measurements on single petroleumbearing fluid inclusions to demonstrate multicharge history in petroleum reservoirs, [Geofluids, (2009), 9, 330-7]'
Blamey,N.J.F., Conliffe, J., Parnell, J., Ryder, A.G., Feely, M. (2010) 'Corrigendum to Application of fluorescence lifetime measurements on single petroleumbearing fluid inclusions to demonstrate multicharge history in petroleum reservoirs, [Geofluids, (2009), 9, 330-7]'. Geofluids, 10 (3) [Details]
(2009) 'Measuring the Micro-Polarity and Hydrogen-Bond Donor/Acceptor Ability of Thermoresponsive N-Isopropylacrylamide/N-tert-Butylacrylamide Copolymer Films Using Solvatochromic Indicators'
Szczupak, B,Ryder, AG,Togashi, DM,Rochev, YA,Gorelov, AV,Glynn, TJ (2009) 'Measuring the Micro-Polarity and Hydrogen-Bond Donor/Acceptor Ability of Thermoresponsive N-Isopropylacrylamide/N-tert-Butylacrylamide Copolymer Films Using Solvatochromic Indicators'. Applied Spectroscopy, 63 :442-449 [ARAN Link] [Details]
(2009) 'Investigating Tryptophan Quenching of Fluorescein Fluorescence under Protolytic Equilibrium'
Togashi, DM,Szczupak, B,Ryder, AG,Calvet, A,O'Loughlin, M (2009) 'Investigating Tryptophan Quenching of Fluorescein Fluorescence under Protolytic Equilibrium'. Journal Of Physical Chemistry A, 113 :2757-2767 [DOI] [ARAN Link] [Details]
(2009) 'A F-bridged Mn(II) molecular square'
Meally, ST,Mason, K,McArdle, P,Brechin, EK,Ryder, AG,Jones, LF (2009) 'A F-bridged Mn(II) molecular square'. Chemical Communications, :7024-7026 [DOI] [ARAN Link] [Details]
(2009) 'Erratum: Investigating tryptophan quenching of fluorescein fluorescence under protolytic equilibrium (Journal of Physical Chemistry (2009) 113 (2757))'
Tosashi,D.M., Szczupak, B., Ryder, A.G., Calvet, A., O'Loughlin, M. (2009) 'Erratum: Investigating tryptophan quenching of fluorescein fluorescence under protolytic equilibrium (Journal of Physical Chemistry (2009) 113 (2757))'. Journal of Physical Chemistry A, 113 (27) [Details]
(2009) 'Trigger factor from the psychrophilic bacterium P Frigidicola is a monomeric chaperone'
Robin,S., Togashi, D.M., Ryder, A.G., Wall, J.G. (2009) 'Trigger factor from the psychrophilic bacterium P Frigidicola is a monomeric chaperone'. JOURNAL OF BACTERIOLOGY, 191 (2):1162-1168 [ARAN Link] [Details]
(2008) 'Frequency domain fluorescence lifetime study of crude petroleum oils'
Owens, P.; Ryder, A.G.; Blamey, N.J.F.; (2008) 'Frequency domain fluorescence lifetime study of crude petroleum oils'. Journal Of Fluorescence, 18 (5):997-1006 [DOI] [ARAN Link] [Details]
(2006) 'Time-resolved fluorescence studies on bovine serum albumin denaturation process'
Togashi,D.M., Ryder, A.G. (2006) 'Time-resolved fluorescence studies on bovine serum albumin denaturation process'. Journal of Fluorescence, 16 (2) [Details]
(2006) 'New reactive fluorophores in the 1,2,3-triazine series'
Butler, RN,Fahy, AM,Fox, A,Stephens, JC,McArdle, P,Cunningham, D,Ryder, AG (2006) 'New reactive fluorophores in the 1,2,3-triazine series'. Tetrahedron Letters, 47 :1721-1724 [DOI] [Details]
(2006) 'Comparison of the fluorescence behavior of a biocrude oil and crude petroleum oils'
Sarma, AK,Ryder, AG (2006) 'Comparison of the fluorescence behavior of a biocrude oil and crude petroleum oils'. Energy & Fuels, 20 :783-785 [DOI] [ARAN Link] [Details]
(2006) 'Time-resolved fluorescence studies on Bovine Serum Albumin denaturation process'
Togashi, D.M.; Ryder, A.G.; (2006) 'Time-resolved fluorescence studies on Bovine Serum Albumin denaturation process'. Journal Of Fluorescence, :153-160 [DOI] [Details]
(2006) 'The Effect of Principal Component Analysis on Machine Learning Accuracy with High Dimensional Spectral Data'
Howley, T., Madden, M.G., O'Connell, M.L., Ryder, A.G. (2006) 'The Effect of Principal Component Analysis on Machine Learning Accuracy with High Dimensional Spectral Data'. Knowledge-Based Systems, 19 (5):363-370 [ARAN Link] [Details]
(2006) 'One-pot synthesis of fluorescent substituted 2,5-Dihydro-1,2,3-Triazines from a cycloaddition, rearrangement, ring-expansion cascade of 1,2,3-Triazolium-1-amide 1,3 dipoles with propiolate esters'
Butler,R.N.,Fahy, A.M.,Fox,A.,Stephen,J.C.,McArdle,P.,Cunningham,D.,Ryder,A.G. (2006) 'One-pot synthesis of fluorescent substituted 2,5-Dihydro-1,2,3-Triazines from a cycloaddition, rearrangement, ring-expansion cascade of 1,2,3-Triazolium-1-amide 1,3 dipoles with propiolate esters'. JOURNAL OF ORGANIC CHEMISTRY, THE, 71 (15):5679-5687 [DOI] [Details]
(2006) 'Thermoresponsive copolymers for tissue engineering and drug delivery'
Carroll, W.; Gorelov, A.; Ryder, A.; Rochev, Y. (2006) 'Thermoresponsive copolymers for tissue engineering and drug delivery'. Tissue Engineering, 124 :1078-1078 [Details]
(2005) 'Spontaneous emission from semiconductor nanocrystals in coupled spherical microcavities'
Yu. P. Rakovich.,Gerlach,M.,Bradley,A.L.,Donegan, J.F.,Bol,J.,Connolly,T.,Przyjalgowski,M.,Ryder,A.,Gaponik,N.,Rogach,A.L. (2005) 'Spontaneous emission from semiconductor nanocrystals in coupled spherical microcavities'. PHYSICA STATUS SOLIDI B-BASIC RESEARCH, 2 (2):858-861 [Details]
(2005) 'Determination of the polymorphic forms of bicifadine hydrochloride by differential scanning calorimetry-thermogravimetric analysis, X-ray powder diffraction, attenuated total reflectance-infrared spectroscopy, and attenuated total reflectance-near-infrared spectroscopy'
McArdle, P.; Gilligan, K.; Cunningham, D.; Ryder, A.; (2005) 'Determination of the polymorphic forms of bicifadine hydrochloride by differential scanning calorimetry-thermogravimetric analysis, X-ray powder diffraction, attenuated total reflectance-infrared spectroscopy, and attenuated total reflectance-near-infrared spectroscopy'. Applied Spectroscopy, 59 :1365-1371 [Details]
(2005) 'Surface enhanced Raman scattering for narcotic detection and applications to chemical biology'
Ryder,A.G. (2005) 'Surface enhanced Raman scattering for narcotic detection and applications to chemical biology'. Current Opinion In Chemical Biology, 9 (5):489-493 [DOI] [ARAN Link] [Details]
(2005) 'An improved genetic programming technique for the classification of Raman spectra'
Hennessy,K., Madden, M.G., Conroy, J., Ryder, A.G. (2005) 'An improved genetic programming technique for the classification of Raman spectra'. Knowledge-Based Systems, 18 (4-5) [Details]
(2004) 'The use of chloroaluminium phthalocyanine tetrasulfonate (AIPcTS) for time-delayed fluorescence imaging'
Gundy,S., Van der Putten, W., Shearer, A., Buckton, D., Ryder, A.G., Ball, M. (2004) 'The use of chloroaluminium phthalocyanine tetrasulfonate (AIPcTS) for time-delayed fluorescence imaging'. Physics in Medicine and Biology, 49 (3) [Details]
(2004) 'The determination of the modulation transfer function MTF) for a time-gated fluorescence imaging system'
Gundy, S.,Van der Putten,W.,Shearer,A.,Buckton,D.,Ryder,A.G. (2004) 'The determination of the modulation transfer function MTF) for a time-gated fluorescence imaging system'. JOURNAL OF BIOMEDICAL OPTICS, 9 (6):1206-1213 [Details]
(2004) 'Time-Resolved Fluorescence Microspectroscopy for Characterizing Crude Oils in Bulk and Hydrocarbon- Bearing Fluid Inclusions'
Ryder, A.G.; Przyjalgowski, M.A.; Feely, M.; Szczupak, B.; Glynn, T.J.; (2004) 'Time-Resolved Fluorescence Microspectroscopy for Characterizing Crude Oils in Bulk and Hydrocarbon- Bearing Fluid Inclusions'. Applied Spectroscopy, 58 (9):1106-1115 [DOI] [Details]
(2004) 'Assessing the maturity of crude petroleum oils using total synchronous fluorescence scan spectra'
Ryder, A.G. (2004) 'Assessing the maturity of crude petroleum oils using total synchronous fluorescence scan spectra'. Journal of Fluorescence, 14 (1) [Details]
(2004) 'Time-resolved fluorescence spectroscopic study of crude petroleum oils: Influence of chemical composition'
Ryder, A.G. (2004) 'Time-resolved fluorescence spectroscopic study of crude petroleum oils: Influence of chemical composition'. Applied Spectroscopy, 58 :613-623 [Details]
(2004) 'Determination of the modulation transfer function for a time-gated fluorescence imaging system'
Gundy, S.; Van der Putten, W.; Shearer, A.; Buckton, D.; Ryder, A.G.; (2004) 'Determination of the modulation transfer function for a time-gated fluorescence imaging system'. Journal Of Biomedical Optics, 9 :1206-1213 [DOI] [Details]
(2004) 'Confined optical modes in small photonic molecules with semiconductor nanocrystals'
Rakovich,Yu.P., Rogach, A.L., Gerlach, M., Bradley, A.L., Donegan, J.F., Connolly, T.M., Boland, J.J., Przyjalgowski, M.A., Ryder, A., Gaponik, N. (2004) 'Confined optical modes in small photonic molecules with semiconductor nanocrystals'. Journal of Applied Physics, 96 (11) [Details]
(2003) 'Evaluation of acridine in Nafion as a fluorescence-lifetime-based pH sensor'
Ryder, A.G..;Power, S.; Glynn, T.J.; (2003) 'Evaluation of acridine in Nafion as a fluorescence-lifetime-based pH sensor'. Applied Spectroscopy, 57 (1):73-79 [ARAN Link] [Details]
(2002) 'Classification of narcotics in solid mixtures using Principal Component Analysis and Raman spectroscopy'
Ryder, AG (2002) 'Classification of narcotics in solid mixtures using Principal Component Analysis and Raman spectroscopy'. Journal Of Forensic Sciences, 47 :275-284 [Details]
(2002) 'Quantitative analysis of crude oils by fluorescence lifetime and steady state measurements using 380 nm excitation'
Ryder, A.G. (2002) 'Quantitative analysis of crude oils by fluorescence lifetime and steady state measurements using 380 nm excitation'. Applied Spectroscopy, 56 (1):107-116 [Details]
(2002) 'Quantitative analysis of crude oils by fluorescence lifetime and steady state measurements using 380 nm excitation'
Ryder, A.G., Glynn, T.J., Feely, M., Barwise, A.J.G. (2002) 'Quantitative analysis of crude oils by fluorescence lifetime and steady state measurements using 380 nm excitation'. Spectrochimica Acta - Part A Molecular And Biomolecular Spectroscopy, 58 (5):1025-1038 [DOI] [Details]
(2002) 'Quantitative analysis of crude oils by fluorescence lifetime and steady state measurements using 380-nm excitation'
Ryder, AG (2002) 'Quantitative analysis of crude oils by fluorescence lifetime and steady state measurements using 380-nm excitation'. Applied Spectroscopy, 56 (1):107-116 [Details]
(2002) 'High pressure diamond and diamond like carbon deposition using a microwave CAP reactor'
McConnell, M.L., Dowling, D.P., Pope, C. Donnelly, K., Ryder, A.G., and O'Connor, G.M. (2002) 'High pressure diamond and diamond like carbon deposition using a microwave CAP reactor'. DIAMOND AND RELATED MATERIALS, 11 (03-Jun):1036-1040 [Details]
(2002) 'A compact violet diode laser based fluorescence lifetime microscope'
Ryder,A.G, Glynn,T.J, Przyjalgowski, M, Szczupak,B. (2002) 'A compact violet diode laser based fluorescence lifetime microscope'. Journal Of Fluorescence, 12 (2):177-180 [DOI] [Details]
(2001) 'Solvent effects on the luminescent properties of conjugated molecules'
Henderson, K,Dalton, AB,Chambers, G,Drury, A,Maier, S,Ryder, AG,Blau, W,Byrne, HJ (2001) 'Solvent effects on the luminescent properties of conjugated molecules'. Synthetic Metals, 119 (1-3):555-556 [DOI] [Details]
(2000) 'Quantitative analysis of cocaine in solid mixtures using Raman spectroscopy and chemometric methods'
Ryder, A.G.; O’Connor, G.M.; Glynn,T.J.; (2000) 'Quantitative analysis of cocaine in solid mixtures using Raman spectroscopy and chemometric methods'. Journal Of Raman Spectroscopy, 31 (3):221-227 [Details]
(1999) 'Identifications and quantitative measurements of narcotics in solid mixtures using near-IR Raman spectroscopy and multivariate analysis'
Alan G. Ryder, Gerard M. O’Connor, and Thomas J. Glynn. (1999) 'Identifications and quantitative measurements of narcotics in solid mixtures using near-IR Raman spectroscopy and multivariate analysis'. Journal Of Forensic Sciences, 44 (5):1013-1019 [ARAN Link] [Details]
(1997) 'Synthesis of novel chiral cyclopentadienes: Synthesis of chiral iron complexes and the crystal structures of [(eta(5)-(1S)-1-(6-methoxynaphthalenyl)-1-(tetramethyl cyclopentadienyl)ethane)Fe(CO)(2)SnCl3] and [(eta(5)-C-5(Me)(4)C(H)(CH3)(C2H5))Fe(CO)-(eta(4)-diphenylbutadiene)](+)[BF4](-)'
McArdle, P, Ryder, AG,Cunningham, D (1997) 'Synthesis of novel chiral cyclopentadienes: Synthesis of chiral iron complexes and the crystal structures of [(eta(5)-(1S)-1-(6-methoxynaphthalenyl)-1-(tetramethyl cyclopentadienyl)ethane)Fe(CO)(2)SnCl3] and [(eta(5)-C-5(Me)(4)C(H)(CH3)(C2H5))Fe(CO)-(eta(4)-diphenylbutadiene)](+)[BF4](-)'. Organometallics, 16 :2638-2645 [Details]

Book Chapters

  Year Publication
(2015) 'Fluorescence Analysis of Thermoresponsive Polymers'
Ryder A. G.; Morris, C. (2015) 'Fluorescence Analysis of Thermoresponsive Polymers' In: Reviews in Fluorescence, Annual volumes 2015. New York: Springer. [DOI] [Details]
(2007) 'Hydrocarbon Fluid Inclusion Fluorescence: A Review'
Ryder, A.G.; Blamey, N.J.F.; (2007) 'Hydrocarbon Fluid Inclusion Fluorescence: A Review' In: Reviews in Fluorescence. New York: Springer. [DOI] [Details]
(2005) 'Analysis of crude petroleum oils using fluorescence spectroscopy'
Ryder, A. G. (2005) 'Analysis of crude petroleum oils using fluorescence spectroscopy' In: Reviews in Fluorescence CD Geddes & JR Lakowicz. New York: Springer. [DOI] [Details]

Conference Publications

  Year Publication
(2005) OptoIreland 2005, published in: Proc SPIE - Int. Soc. Opt. Eng. vol. 5826
O'Connell, M., Ryder, A.G., Leger, M.N., Howley, T., Madden, M.G. (2005) Classification of a target analyte in solid mixtures using principal component analysis, support vector machines and Raman spectroscopy OptoIreland 2005, published in: Proc SPIE - Int. Soc. Opt. Eng. vol. 5826 RDS, Dublin, Ireland, , 04-APR-05 - 06-APR-05 , pp.340-350 [Details]
(2006) KNOWLEDGE-BASED SYSTEMS
Howley, T,Madden, MG,O'Connell, ML,Ryder, AG (2006) The effect of principal component analysis on machine learning accuracy with high-dimensional spectral data KNOWLEDGE-BASED SYSTEMS , pp.363-370 [DOI] [Details]
(2005) OptoIreland 2005, published in: Proc SPIE - Int. Soc. Opt. Eng. vol. 5826
Ryder, A.G, Szczupak,B, Rotchev,Y.A, Klymchenko,A.S, Gorelov,A, Glynn,T.J. (2005) A fluorescence methodology for assessing the polarity and composition of novel thermoresponsive hydrophilic/hydrophobic copolymer system OptoIreland 2005, published in: Proc SPIE - Int. Soc. Opt. Eng. vol. 5826 Dublin, Ireland, , pp.1-11 [DOI] [Details]
(2005) KNOWLEDGE-BASED SYSTEMS
Hennessy, K,Madden, MG,Conroy, J,Ryder, AG (2005) An improved genetic programming technique for the classification of Raman spectra KNOWLEDGE-BASED SYSTEMS , pp.217-224 [DOI] [Details]
(2004) 47th Annual Irish Geological Research Meeting 2004, NUI-Galway, 20-22 Feb., 2004
Przyjalgowski,M.A., Ryder,A.G.,Feely,M., Glynn,T.J. (2004) Towards non-destructive characterization of hydrocarbon bearing fluid inclusions using time-resolved fluorescence (TRF) microscopy 47th Annual Irish Geological Research Meeting 2004, NUI-Galway, 20-22 Feb., 2004 [Details]
(2002) 45th Annual Irish Geological Research Meeting 2002, Dublin, 22-24 Feb., 2002
Przyjalgowski,M.A.,Ryder, A.G.,Szczukap,B.,Glynn,T.J.,Feely,M. (2002) Preliminary studies with a diode laser-based fluorescence lifetime microscope: a new measurement methodology for petroleum bearing fluid inclusions . In: Irish Journal of Earth Sciences eds. 45th Annual Irish Geological Research Meeting 2002, Dublin, 22-24 Feb., 2002 , pp.98-99 [Details]
(2002) A compact violet diode laser-based fluorescence lifetime microscope
Ryder, AG,Glynn, TJ,Przyjalgowski, M,Szczupak, B (2002) JOURNAL OF FLUORESCENCE A compact violet diode laser-based fluorescence lifetime microscope , pp.177-180 [Details]

Other Journals

  Year Publication
(2010) 'Rapid, low-cost, quantitative characterization of cell culture media using a combination of spectroscopic and chemometric methods'
Ryder, A.G.; Li, B.; Leister, K.J.; (2010) 'Rapid, low-cost, quantitative characterization of cell culture media using a combination of spectroscopic and chemometric methods' International Drug Discovery, :18-21. [Details]
(2007) 'Fluorescence study of Bovine Serum Albumin and Ti and Sn Oxide Nanoparticles Interactions'
Togashi, D.M., Ryder,A.G., McMahon, D., Dunne, P., McManus, J. (2007) 'Fluorescence study of Bovine Serum Albumin and Ti and Sn Oxide Nanoparticles Interactions' Proc SPIE - Int. Soc. Opt. Eng. 6628, 6628 . [ARAN Link] [Details]
(2004) 'Fluorescence emission from petroleum; a valuable information source for petroleum analysis'
Ryder, A.G.; Iwanski, P.; Montanari, L. (2004) 'Fluorescence emission from petroleum; a valuable information source for petroleum analysis' Tpoint (in-house journal for EniTecnologie), 2 :9-14. [ARAN Link] [Details]
(2005) 'An improved genetic programming technique for the classification of Raman spectra'
Hennessy,K., Madden,M.G., Conroy,J., Ryder,A.G. (2005) 'An improved genetic programming technique for the classification of Raman spectra' BCS Conference S:, :152-161. [Details]
(2005) 'Qualitative and quantitative analysis of chlorinated solvents using Raman spectroscopy and machine learning'
Conroy, J.; Ryder, A.G.; Leger, M.N.; Hennessey, K.; Madden, M.G. (2005) 'Qualitative and quantitative analysis of chlorinated solvents using Raman spectroscopy and machine learning' Proc SPIE - Int. Soc. Opt. Eng, 5826 :131-142. [DOI] [Details]
(2005) 'Analysis of hydrocarbon bearing fluid inclusions HCFI) using time-resolved fluorescence spectroscopy'
Przyjalgowski, M.A.; Ryder, A.G.; Feely, M.; Glynn, T.J.; (2005) 'Analysis of hydrocarbon bearing fluid inclusions HCFI) using time-resolved fluorescence spectroscopy' Proc SPIE - Int. Soc. Opt. Eng, 5826 :173-184. [DOI] [ARAN Link] [Details]
(2003) 'Machine Learning Methods for Quantitative Analysis of Raman Spectroscopy Data'
Madden,M.G., Ryder,A.G. (2003) 'Machine Learning Methods for Quantitative Analysis of Raman Spectroscopy Data' Proc SPIE - Int. Soc. Opt. Eng, 4876 :1130-1139. [Details]
(2003) 'Time-Gated Fluorescence Imaging of Chloroaluminum Phthalocyanine Tetrasulfonate in a Tissue Phantom'
Gundy,S.,Van der Putten, W.J.,Shearer, A.,Buckton,D.J,Ryder,A.G.,Ball,M. (2003) 'Time-Gated Fluorescence Imaging of Chloroaluminum Phthalocyanine Tetrasulfonate in a Tissue Phantom' Proc SPIE - Int. Soc. Opt. Eng, 4876 . [Details]
(2003) 'Influence of chemical composition on the fluorescence lifetimes of crude petroleum oils'
Ryder, A.G.; Glynn, T.J.; Feely, M.; (2003) 'Influence of chemical composition on the fluorescence lifetimes of crude petroleum oils' Proc SPIE - Int. Soc. Opt. Eng, 4876 :1188-1195. [ARAN Link] [Details]
(2003) 'Fluorescence lifetime based pH sensing using Resorufin'
Ryder,A.G, Power,S, Glynn,T.J. (2003) 'Fluorescence lifetime based pH sensing using Resorufin' Proc SPIE - Int. Soc. Opt. Eng, 4876 :827-835. [Details]
(2003) 'Time-delayed fluorescence imaging of a porphycene derivative'
Gundy,S., Van der Putten,W.J., Shearer,A., Buckton,D.J., Ryder,A.G., Ball,M. (2003) 'Time-delayed fluorescence imaging of a porphycene derivative' Proc SPIE - Int. Soc. Opt. Eng, 4952 . [Details]
(2001) 'Time-resolved fluorescence studies of porphycene and tetrasulfonated phthalocyanine dyes in varying solvents'
Gundy,S, Van der Putten, W, Shearer,A, Ryder,A.G, Ball,M. (2001) 'Time-resolved fluorescence studies of porphycene and tetrasulfonated phthalocyanine dyes in varying solvents' Proc SPIE - Int. Soc. Opt. Eng, 4432 . [Details]
(2001) 'Time-domain measurement of fluorescence lifetime variation with pH'
Ryder, A.G; Power, S; Glynn, T.J; Morrison, J.J.; (2001) 'Time-domain measurement of fluorescence lifetime variation with pH' Proc SPIE - Int. Soc. Opt. Eng, 4259 :102-109. [ARAN Link] [Details]

Article

  Year Publication
(2010) Rapid, low-cost, quantitative characterization of cell culture media using a combination of spectroscopic and chemometric methods.
Ryder, A.G.; Li, B.; Leister, K.J.; (2010) Rapid, low-cost, quantitative characterization of cell culture media using a combination of spectroscopic and chemometric methods. 9225 Priority Way West Drive, Suite 120, Indianapolis, IN 46240: Article [Details]

Conference Contributions

  Year Publication
(2015) Eastern Analytical Symposium,,
A.G. Ryder (2015) The use of multi-dimensional fluorescence spectroscopy for the quantitative analysis of liquid media: from hydrolysates to protein solutions. [Invited Oral Presentation], Eastern Analytical Symposium,, Somerset, NJ, USA , 15-NOV-15 - 18-NOV-15. [Details]
(2005) Microscopical Society of Ireland's 29th Annual Symposium,
Murray,R.; Ryder,A.G. (2005) Development of a wide field fluorescence imaging microscope using a fast gated ICCD camera. [Poster Presentation], Microscopical Society of Ireland's 29th Annual Symposium, NUI Galway, Galway, Ireland , 07-SEP-05 - 09-SEP-05. [Details]
(2004) Polymer Networks 2004,
Szczupak, B*, Ryder,A.G, Rochev,Y.A, Klymchenko,A.S, Gorelov,A, Glynn,T.J. (2004) A fluorescence methodology for assessing the polarity of hydrophilic polymers. Polymer Networks. [Conference Organising Committee Chairperson], Polymer Networks 2004, Bethesda, MD, USA , 15-AUG-04 - 19-AUG-04. [Details]
(2004) 47th Annual Irish Geological Research Meeting,
Przyjalgowski, M.A.; Ryder, A.G.; Feely, M.; Glynn, T.J. (2004) Towards non-destructive characterization of hydrocarbon bearing fluid inclusions using time-resolved fluorescence TRF) microscopy. [Oral Presentation], 47th Annual Irish Geological Research Meeting, TCD, Dublin, Ireland , 20-FEB-04 - 22-FEB-04. [Details]
(2002) Microscopical Society of Ireland's 26th Annual Symposium,
Szczukap, B*, Ryder, A.G, Przyjalgowski, M, Glynn,T.J. (2002) Development of a low cost motorized XY stage with micron accuracy for fluorescence lifetime imagin microscopy. [Poster Presentation], Microscopical Society of Ireland's 26th Annual Symposium, NUI Galway, Galway, Ireland , 28-AUG-02 - 30-AUG-02. [Details]
(2002) 14th Meeting of the British Organic Geochemical Society BOGS,
Ryder, A.G.,Murray-Hayden, E.,Przjalgowski, M.,Feely, M.,Glynn.T.J. (2002) Time-resolved fluorescence spectroscopy of petroleum oils. [Oral Presentation], 14th Meeting of the British Organic Geochemical Society BOGS, Newcastle, England , 02-JUL-02 - 03-JUL-02. [Details]
(2002) OptoIreland 2002,
Przyjalgowski, M.; Ryder, A.G.; Szczupak, B.; Feely, M.; Glynn,T.J. (2002) Time-Resolved Fluorescence spectroscopy of common fluid inclusion host materials. [Poster Presentation], OptoIreland 2002, Galway, Ireland , 05-SEP-02 - 06-SEP-02. [Details]
(2001) Ireland's deepwater frontier: results from the petroleum infrastructure programme,
Parnell,J., Feely,M., Ryder,A., Murray-Hayden, E., (2001) The application of fluid inclusion studies to oil and gas exploration. [Conference Organising Committee Chairperson], Ireland's deepwater frontier: results from the petroleum infrastructure programme, Dublin, Ireland , 12-SEP-01 - 13-SEP-01. [Details]
(2000) International Conference on Forensic Science: From Crime Scene to Court Room,
Ryder, A.G.; O'Connor, G.M.; Glynn,T.J. (2000) Measurement of Narcotic Concentrations by Laser Raman Spectroscopy. [Poster Presentation], International Conference on Forensic Science: From Crime Scene to Court Room, Dublin Castle, Dublin, Ireland , 02-MAY-00 - 05-MAY-00. [Details]
(2015) PEGS Europe: Protein & Antibody Engineering Summit,
Ryder, A.G. (2015) Comprehensive, Quantitative Bioprocess Productivity Monitoring Using Fluorescence EEM Spectroscopy and Chemometrics. [Invited Oral Presentation], PEGS Europe: Protein & Antibody Engineering Summit, Lisbon Portugal , 02-NOV-15 - 06-NOV-15. [Details]
(2015) 11th Australian Conference on Vibrational Spectroscopy,
A. G. Ryder*, B. Li, A. Calvet, C. Morris, and Y. Casamayou-Boucau. (2015) Low-concentration Analyte Quantification in the Solid State Using Raman Spectroscopy and Chemometrics. [Plenary Lecture], 11th Australian Conference on Vibrational Spectroscopy, University of Sydney, Sydney, Australia , 28-SEP-15 - 02-OCT-15. [Details]
(2015) XV Chemometrics in Analytical Chemistry,,
A. G. Ryder, B. Li, A. Calvet, C. Morris, and Y. Casamayou-Boucau. (2015) Low content quantification in solid powder matrix using Raman spectroscopy and chemometric methods. [Keynote Address], XV Chemometrics in Analytical Chemistry,, Changsha, Hunan province, China , 22-JUN-15 - 26-JUN-15. [Details]
(2015) Animal Cell Technology Industrial Platform meeting,,
Ryder, A.G., (2015) Advances in the use of multi-dimensional fluorescence spectroscopies for the quantitative analysis of cell culture media and proteins: new tools for process and product analytics. [Invited Lecture], Animal Cell Technology Industrial Platform meeting,, Lisbon Portugal , 06-MAY-15 - 08-MAY-15. [Details]
(2015) 14th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging and Probes,,
Islam, M.Z.; Ryder, A.G.; (2015) Environmentally insensitive and photostable dyes: Novel 2, 5 Di-hydro 1, 2, 3 triazine. [Poster Presentation], 14th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging and Probes,, Würzburg, Germany , 13-SEP-15 - 16-SEP-15. [Details]
(2015) 14th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging and Probes,,
Groza, R.C; Li, B. ; Ryder, A.G. (2015) Anisotropy Resolved Multi-dimensional Emission Spectroscopy (ARMES): A new tool for protein structure analysis. [Poster Presentation], 14th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging and Probes,, Würzburg, Germany , 13-SEP-15 - 16-SEP-15. [Details]
(2014) The Bioprocessing Summit,
Ryder, A.G., (2014) Comprehensive, quantitative bioprocess monitoring using fluorescence spectroscopy. [Invited Oral Presentation], The Bioprocessing Summit, Renaissance Boston Waterfront Hotel, Boston, Mass., USA , 20-AUG-14 - 21-AUG-14. [Details]
(2014) The Bioprocessing Summit,
Ryder, A.G. (2014) Fast, easy, and reliable methods for quantifying cell culture media variance and stability: Or…how to taste your super soup. [Oral Presentation], The Bioprocessing Summit, Renaissance Boston Waterfront Hotel, Boston, Mass., USA , 20-AUG-14 - 21-AUG-14. [Details]
(2014) 3rd annual Biopharmaceutical Raw Materials: Qualification, Analysis, & supply chain management,,
Ryder, A.G. (2014) Quantitative monitoring raw material and cell culture media quality using fast fluorescence based analytical methods. [Invited Oral Presentation], 3rd annual Biopharmaceutical Raw Materials: Qualification, Analysis, & supply chain management,, Cologne, Germany , 24-JUN-14 - 25-JUN-14. [Details]
(2014) Biological Production Forum,
Ryder, A.G. (2014) Comprehensive, quantitative bioprocess monitoring using spectroscopy and chemometrics: raw materials, cell culture media, and bioprocess broths. [Invited Oral Presentation], Biological Production Forum, CityWest, Dublin , 12-MAY-14 - 14-MAY-14. [Details]
(2013) Combining Multidimensional Fluorescence Spectroscopy and Chemometrics for Industrial Biopharmaceutical Applications,
A.G. Ryder, B. Li, A. Calvet, C. Morris, M. Shanahan, and B. Kissane (2013) 13th Methods and Applications of Fluorescence (poster presentation). [Conference Organising Committee Chairperson], Combining Multidimensional Fluorescence Spectroscopy and Chemometrics for Industrial Biopharmaceutical Applications, Genoa, Italy , 08-SEP-13 - 11-SEP-13. [Details]
(2013) Bioproduction 2013,
Alan G. Ryder,* Boyan Li, Bryan H. Ray, Kirk J. Leister. (2013) Quantitative performance monitoring of a mammalian cell based bioprocess using Raman spectroscopy. [Invited Lecture], Bioproduction 2013, Burlington Hotel, Dublin , 22-OCT-13 - 23-OCT-13. [Details]
(2013) SciX 2013,
A. G. Ryder (2013) Raman spectroscopy in biopharmaceutical manufacturing. [Invited Lecture], SciX 2013, Milwaukee, WI, USA , 29-SEP-13 - 04-OCT-13. [Details]
(2012) Biopharmaceutical Raw Materials: Qualification, Analysis, & supply chain management,
Alan G. Ryder. (2012) Quantitative analysis of cell culture media using multi-dimensional fluorescence spectroscopy. [Invited Oral Presentation], Biopharmaceutical Raw Materials: Qualification, Analysis, & supply chain management, Cologne, Germany , 27-JUN-12 - 28-JUN-12. [Details]
(2012) 26th International Forum and Exhibition Process Analytical Technology,
Ryder, A.G., Li, B., and Kissane, B. (2012) Quantitative Analysis of Cell Culture Media using Raman Spectroscopy. [Invited Oral Presentation], 26th International Forum and Exhibition Process Analytical Technology, Baltimore, MD, USA , 22-JAN-12 - 25-JAN-12. [Details]
(2011) Process2Product, Translating Process Knowledge into Quality Biological Products,
Alan G. Ryder (2011) Rapid, Quantitative analytical methods for hydrosylates using in cell culture media: a spectroscopic approach. [Invited Oral Presentation], Process2Product, Translating Process Knowledge into Quality Biological Products, Omni Shoreham, Washington DC, USA , 04-OCT-11 - 06-OCT-11. [Details]
(2011) 12th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging and Probes,
B. Li and A.G. Ryder (2011) Biannual Fluorescence conference. [Poster Presentation], 12th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging and Probes, Strasbourg, France , 11-SEP-11 - 14-SEP-11. [Details]
(2011) 12th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging and Probes,
B. Kissane, B. Li, and A.G. Ryder (2011) Biannual fluorescence conference. [Poster Presentation], 12th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging and Probes, Strasbourg, France , 11-SEP-11 - 14-SEP-11. [Details]
(2010) Process2Product, Translating Process Knowledge into Quality Biological Products,
Alan G. Ryder (2010) Rapid, Low-Cost, Quantitative Characterization of Cell Culture Media Using a Combination of Spectroscopic and Chemometric Methods. [Invited Oral Presentation], Process2Product, Translating Process Knowledge into Quality Biological Products, Hyatt Regency Bethesda, Bethesda, MD, USA , 21-OCT-10 - 22-OCT-10. [Details]
(2006) Annual Symposium of the Microscopical Society of Ireland,
Alan G. Ryder and Alexander Black (Anatomy) (2006) Microscopy conference, focussed on early-stage researchers. [Conference Organising Committee Chairperson], Annual Symposium of the Microscopical Society of Ireland, Galway , 30-AUG-06 - 01-SEP-06. [Details]
(2006) 6th International ELMI meeting,
Togashi, D.M, Ryder, A.G. (2006) Real-time measurement of absorption of bovine serum albumin on silica glass by confocal fluorescence microscopy. [Poster Presentation], 6th International ELMI meeting, Ofir, Portugal , 30-JUN-06 - 02-JUN-06. [Details]
(2005) Microscopical Society of Ireland's 29th Annual Symposium,
Togashi,D.M, Ryder,A.G. (2005) Study of Protein Adsorption on Silica Glass Surface by Confocal Fluorescence Microscopy. [Oral Presentation], Microscopical Society of Ireland's 29th Annual Symposium, DIT, Dublin , 07-SEP-05 - 09-SEP-05. [Details]
(2005) OptoIreland 2005, published in: Proc SPIE - Int. Soc. Opt. Eng. vol. 5826,
Byrne,H.J., Lewis, E., MacCraith,B.D., McGlynn,E.,McLaughlin,J.A., O'Sullivan,G.D., Ryder,A.G., Walsh,J.E. (2005) Optical Sensing and Spectroscopy. [Conference Organising Committee Chairperson], OptoIreland 2005, published in: Proc SPIE - Int. Soc. Opt. Eng. vol. 5826, RDS, Dublin, Ireland , 04-APR-05 - 06-APR-05. [Details]
(2005) 32nd FACSS Federation of Analytical Chemistry and Spectroscopy Societies,
Leger, M.N.,O'Connell, M.L.,Ryder, A.G., Hennessey, K., Madden, M.G. (2005) Classification and quantification of a pharmaceutical analyte in solid mixtures with Raman spectroscopy. [Conference Organising Committee Chairperson], 32nd FACSS Federation of Analytical Chemistry and Spectroscopy Societies, Quebec City, Canada , 01-OCT-05 - 02-OCT-02. [Details]
(2005) Opto-Ireland (SPIE regional meeting),
Alan G. Ryder (2005) Optics & Photonics Conference. [Chaired Session], Opto-Ireland (SPIE regional meeting), RDS, Dublin , 04-APR-05 - 05-APR-05. [Details]
(2004) Microscopical Society of Ireland's 28th Annual Symposium,
Ryder,A, Przyjalgowski,M, Feely,M. (2004) Time-resolved fluorescence micro-spectroscopy for characterizing crude oils in microscopic hydrocarbon bearing fluid inclusions. [Invited Oral Presentation], Microscopical Society of Ireland's 28th Annual Symposium, TCD, Dublin , 01-SEP-04 - 03-SEP-04. [Details]
(2004) An Improved Genetic Programming Technique for Identification of Solvents from Raman Spectra. AI2004: The Twenty-fourth SGAI International Conference on Innovative Techniques and Applications of Artificial Intelligence Cambridge, UK,
Hennessy,K.,Madden, M.G.,Conroy,J.,Ryder,A.G. (2004) Oral presentation. [Conference Organising Committee Chairperson], An Improved Genetic Programming Technique for Identification of Solvents from Raman Spectra. AI2004: The Twenty-fourth SGAI International Conference on Innovative Techniques and Applications of Artificial Intelligence Cambridge, UK, Cambridge UK , 13-DEC-04 - 15-DEC-04. [Details]
(2005) Applicability of Raman spectroscopy for detection and identification of illicit materials in complex solid mixtures,
Leger,M.N, Ryder,A.G., Madden,M.G. (2005) 32nd FACSS Federation of Analytical Chemistry and Spectroscopy Societies. [Poster Presentation], Applicability of Raman spectroscopy for detection and identification of illicit materials in complex solid mixtures, Quebec City, Canada , 01-OCT-05 - 02-OCT-05. [Details]
(2003) 26th Annual Symposium of the Microscopical Society of Ireland,
Alan Ryder, Michael Ball, Alexander Black (2003) Microscopy Conference. [Conference Organising Committee Chairperson], 26th Annual Symposium of the Microscopical Society of Ireland, NUIG, Galway , 28-AUG-03 - 30-AUG-02. [Details]
(2003) 8th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging and Probes,
Ryder, A.G. (2003) Assessing the Maturity of Crude Petroleum Oils Using Total Synchronous Fluorescence Scan Spectra. [Poster Presentation], 8th Conference on Methods and Applications of Fluorescence: Spectroscopy, Imaging and Probes, Lisbon, Portugal , 24-AUG-03 - 27-AUG-03. [Details]
(2002) 14th Meeting of the British Organic Geochemical Society (BOGS,
Ryder, A.G.,Murray-Hayden, E.,Przyjalgowski, M.,Feely, M.,Glynn,T.J. (2002) Time-resolved fluorescence spectroscopy of petroleum oils. [Published Abstract], 14th Meeting of the British Organic Geochemical Society (BOGS, Newcastle, England , 02-JUL-02 - 03-JUL-02. [Details]
(2000) Gordon Research Conference: Illicit Substance Detection - Explosives,
Ryder, A.G. (2000) In-situ analysis of explosives by optical methods. [Invited Oral Presentation], Gordon Research Conference: Illicit Substance Detection - Explosives, New London, Connecticut, USA , 08-JUL-00 - 13-JUL-00. [Details]
(1998) Microscopical Society of Ireland's 22nd Annual Symposium,
Ryder, A.G.,Feely, M., Moran, R., O'Connor, G.M. & T.J. Glynn. (1998) Raman Microscopy and the Analysis of Microscopic Fluid Inclusions. [Oral Presentation], Microscopical Society of Ireland's 22nd Annual Symposium, Galway, Ireland , 02-SEP-98 - 03-SEP-98. [Details]
(1998) EU symposium: Fighting Crime Through Technology,
Ryder, A.G, O'Connor, G.M, Glynn,T.J. (1998) Near-IR Raman spectroscopy as a tool for the identification of illegal drugs in solid mixtures. [Oral Presentation], EU symposium: Fighting Crime Through Technology, London, England , 24-MAR-98 - 25-MAR-98. [Details]

Conference Paper

  Year Publication
(2006) Analysis of Replication Proteins in Living Human Cells. Microscopical Society of Ireland's 30th Annual Symposium.
Braet,C, Stephan, H, Togashi,D, Ryder,A, Nasheuer,H.P. (2006) Analysis of Replication Proteins in Living Human Cells. Microscopical Society of Ireland's 30th Annual Symposium. Conference Paper [Details]
(2005) Qualitative and quantitative analysis of chlorinated solvents using Raman spectroscopy and machine learning. OptoIreland.
Conroy,J.,Ryder,A.G.,Leger,M.N.,Hennessy,K.,Madden,M.G. (2005) Qualitative and quantitative analysis of chlorinated solvents using Raman spectroscopy and machine learning. OptoIreland. Conference Paper [Details]
(2005) Combining Genetic Algorithms, Neural networks and Wavelet Transforms for Analysis of Raman Spectra. Proceedings of 15th Irish Conference on Artificial Intelligence & Cognitive Science.
K. Hennessy, M.G. Madden and A.G. Ryder (2005) Combining Genetic Algorithms, Neural networks and Wavelet Transforms for Analysis of Raman Spectra. Proceedings of 15th Irish Conference on Artificial Intelligence & Cognitive Science. Conference Paper [Details]
(2005) Investigation into the use of PCA with Machine Learning for the Identification of Narcotics based on Raman Spectroscopy. Proceedings of 16th Irish Conference on Artificial Intelligence & Cognitive Science.
Howley, T.,Madden, M.G.,O'Connell,M.L.,Ryder,A.G. (2005) Investigation into the use of PCA with Machine Learning for the Identification of Narcotics based on Raman Spectroscopy. Proceedings of 16th Irish Conference on Artificial Intelligence & Cognitive Science. Conference Paper [Details]
(2005) A fluorescence methodology for assessing the polarity and composition of novel thermoresponsive hydrophilic/hydrophobic copolymer system. Proc SPIE - Int. Soc. Opt. Eng.
Ryder,A.G, Szczupak,B, Rotchev,Y.A, Klymchenko, A.S, Gorelov,A, Glynn,T.J. (2005) A fluorescence methodology for assessing the polarity and composition of novel thermoresponsive hydrophilic/hydrophobic copolymer system. Proc SPIE - Int. Soc. Opt. Eng. Conference Paper [Details]
(2005) A fluorescence methodology for assessing the polarity and composition of novel thermoresponsive hydrophylic/hydrophobic copolymer system. OptoIreland RDS.
Ryder,A.G, Szczupak,B, Rotchev,Y.A, Klymchenko, A.S, Gorelov,A, Glynn,T.J. (2005) A fluorescence methodology for assessing the polarity and composition of novel thermoresponsive hydrophylic/hydrophobic copolymer system. OptoIreland RDS. Conference Paper [Details]
(2004) Micro-PL studies of small photonic molecules with semiconductor nanocrystals. Microscopical Society of Ireland's 28th Annual Symposium.
YuP.Rakovich.,Gerlach,M.,Bradley,A.L.,Donegan,J.F.,Bol,J.,Connolly,T.,Przyjalgowski,M.A.,Ryder,A.,Gaponik,N.,Rogach,A.L. (2004) Micro-PL studies of small photonic molecules with semiconductor nanocrystals. Microscopical Society of Ireland's 28th Annual Symposium. Conference Paper [Details]
(2003) The first nanosecond time-resolved fluorescence studies of hydrocarbon bearing fluid inclusions using a diode laser based fluorescence lifetime microscope. Microscopical Society of Ireland's 27th Annual Symposium.
Przyjalgowski, M.,Ryder, A.G.,Feely, M.,Szczupak, B.,Glynn,T.J. (2003) The first nanosecond time-resolved fluorescence studies of hydrocarbon bearing fluid inclusions using a diode laser based fluorescence lifetime microscope. Microscopical Society of Ireland's 27th Annual Symposium. Conference Paper [Details]
(2003) Time-Gated Fluorescence Imaging of Chloroaluminum Phthalocyanine Tetrasulfonate in a Tissue Phantom. Proc SPIE - Int. Soc. Opt. Eng.
Gundy, S.,Van der Putten, W.J.,Shearer, A.,Buckton, D.J.,Ryder, A.G.,Ball,M. (2003) Time-Gated Fluorescence Imaging of Chloroaluminum Phthalocyanine Tetrasulfonate in a Tissue Phantom. Proc SPIE - Int. Soc. Opt. Eng. Conference Paper [Details]
(2003) Time-delayed fluorescence imaging of a porphycene derivative. SPIE - Int. Soc. Opt. Eng.
Gundy, S.,Van der Putten, W.J.,Shearer, A.,Buckton, D.J.,Ryder, A.G.,Ball,M. (2003) Time-delayed fluorescence imaging of a porphycene derivative. SPIE - Int. Soc. Opt. Eng. Conference Paper [Details]
(2003) Machine Learning Methods for Quantitative Analysis of Raman Spectroscopy Data. Proc SPIE - Int. Soc. Opt. Eng.
Madden, M.G.,Ryder,A.G. (2003) Machine Learning Methods for Quantitative Analysis of Raman Spectroscopy Data. Proc SPIE - Int. Soc. Opt. Eng. Conference Paper [Details]
(2003) Influence of chemical composition on the fluorescence lifetimes of crude petroleum oils. Proc SPIE - Int. Soc. Opt. Eng.
Ryder, A.G.,Glynn, T.J.,Feely,M. (2003) Influence of chemical composition on the fluorescence lifetimes of crude petroleum oils. Proc SPIE - Int. Soc. Opt. Eng. Conference Paper [Details]
(2003) Fingerprinting of Crude Petroleum Oils in Bulk form and in Fluid Inclusions, using Time-Resolved Fluorescence Microscopy. 46th Annual Irish Geological Research Meeting.
Przyjalgowski, M.,Ryder, A.G.,Feely, M.,Glynn,T.J. (2003) Fingerprinting of Crude Petroleum Oils in Bulk form and in Fluid Inclusions, using Time-Resolved Fluorescence Microscopy. 46th Annual Irish Geological Research Meeting. Conference Paper [Details]
(2002) Fluorescence lifetime FL) measurements of crude oils: towards the in-situ characterization of oil-bearing fluid inclusions. 45th Annual Irish Geological Research Meeting.
Murray-Hayden, E.,Ryder, A.,Feely,M. (2002) Fluorescence lifetime FL) measurements of crude oils: towards the in-situ characterization of oil-bearing fluid inclusions. 45th Annual Irish Geological Research Meeting. Conference Paper [Details]
(2002) Preliminary studies with a diode laser based fluorescence lifetime microscope DLFLM) - a new measurement methodology for petroleum bearing fluid inclusions. 45th Annual Irish Geological Research Meeting.
Przyjalgowski, M.,Ryder, A.G.,Szczupak, B.,Glynn, T.J.,Feely, M.,Murray-Hayden,E. (2002) Preliminary studies with a diode laser based fluorescence lifetime microscope DLFLM) - a new measurement methodology for petroleum bearing fluid inclusions. 45th Annual Irish Geological Research Meeting. Conference Paper [Details]
(2002) Development of a low cost motorized XY stage with micron accuracy for fluorescence lifetime imaging microscopy. Microscopical Society of Ireland's 26th Annual Symposium.
Szczupak, B.,Ryder, A.G.,Przyjalgowski, M.,Glynn,T.J. (2002) Development of a low cost motorized XY stage with micron accuracy for fluorescence lifetime imaging microscopy. Microscopical Society of Ireland's 26th Annual Symposium. Conference Paper [Details]
(2002) Development of a diode laser based fluorescence lifetime microscope. Microscopical Society of Ireland's 26th Annual Symposium.
Przyjalgowski, M.,Ryder, A.G.,Szczupak, B.,Glynn,T.J. (2002) Development of a diode laser based fluorescence lifetime microscope. Microscopical Society of Ireland's 26th Annual Symposium. Conference Paper [Details]
(2001) Time-domain measurement of fluorescence lifetime variation with pH. Proc SPIE - Int. Soc. Opt. Eng.
Ryder, A.G.,Power, S.,Glynn, T.J.,Morrison,J.J. (2001) Time-domain measurement of fluorescence lifetime variation with pH. Proc SPIE - Int. Soc. Opt. Eng. Conference Paper [Details]
(2001) Time-resolved fluorescence studies of porphycene and tetrasulfonated phthalocyanine dyes in varying solvents. Proc SPIE - Int. Soc. Opt. Eng.
Gundy, S.,Van der Putten, W.,Shearer, A.,Ryder, A.G.,Ball,M. (2001) Time-resolved fluorescence studies of porphycene and tetrasulfonated phthalocyanine dyes in varying solvents. Proc SPIE - Int. Soc. Opt. Eng. Conference Paper [Details]

Conference Poster

  Year Publication
(2006) Analysis or Replication Proteins in Living Human Cells. Irish Association for Cancer Research/Irish Society for Medical Oncology, Joint Annual Cancer Research meeting.
Braet,C, Stephan,H, Togashi,D, Ryder,A, Nasheuer,H.P. (2006) Analysis or Replication Proteins in Living Human Cells. Irish Association for Cancer Research/Irish Society for Medical Oncology, Joint Annual Cancer Research meeting. Conference Poster [Details]
(2005) Classification of a target analyte in solid mixtures using principal component analysis, support vector machines and Raman spectroscopy. OptoIreland.
O'Connell,M.,Ryder, A.G.,Leger, M.N.,Howley,T.,Madden,M.G. (2005) Classification of a target analyte in solid mixtures using principal component analysis, support vector machines and Raman spectroscopy. OptoIreland. Conference Poster [Details]
(2005) Time-resolved fluorescence studies on bovine serum albumin denaturation process. MAF 9, 9th International Conference on Methods and Applications of Fluorescence: Spectroscopy, Imagin and Probes.
Togashi,D, Ryder,A.G. (2005) Time-resolved fluorescence studies on bovine serum albumin denaturation process. MAF 9, 9th International Conference on Methods and Applications of Fluorescence: Spectroscopy, Imagin and Probes. Conference Poster [Details]
(2005) Thermoresponsive copolymers for tissue engineering and drug delivery. 8th Annual Meeting of Tissur Engineering Society International.
Gorelov,A, Ryder,A, Carroll,W, Rochev,Y. (2005) Thermoresponsive copolymers for tissue engineering and drug delivery. 8th Annual Meeting of Tissur Engineering Society International. Conference Poster [Details]
(2003) Polymer polarity measurements using fluorescence techniques. BioNet.
Szczupak, B.,Ryder, A.G.,Rochev, Y.A.,Gorelov, A.V.,Glynn,T.J. (2003) Polymer polarity measurements using fluorescence techniques. BioNet. Conference Poster [Details]
(2003) A Regression Model to Depict Time-resolved Images Using a Phthalocyanine Derivative. 8th EFOMP conference.
Gundy, S.,Van der Putten, W.,Shearer, A.,Buckton, D.,Ryder, A.,Ball,M. (2003) A Regression Model to Depict Time-resolved Images Using a Phthalocyanine Derivative. 8th EFOMP conference. Conference Poster [Details]
(2003) Time Resolved Fluorescence Spectroscopy For Characterising Crude Oils In Bulk And Fluid Inclusions. 21st IMOG International Meeting of Organic Geochemists.
Ryder, A.G.,Przyjalgowski, M.,Feely, M.,Glynn,TJ. (2003) Time Resolved Fluorescence Spectroscopy For Characterising Crude Oils In Bulk And Fluid Inclusions. 21st IMOG International Meeting of Organic Geochemists. Conference Poster [Details]
(2002) Integrating a low cost motorized XY stage with a Time Correlated Single Photon Counting based microscopy system. OptoIreland.
Szczupak, B.,Ryder, A.G.,Przyjalgowski, M.,Glynn,T.J. (2002) Integrating a low cost motorized XY stage with a Time Correlated Single Photon Counting based microscopy system. OptoIreland. Conference Poster [Details]
(2001) Using fluorescence lifetime measurements to quantitatively characterise crude oils. IMOG 2001 International Meeting of Organic Geochemists.
Ryder, A.G.,Glynn, T.J.,Feely, M.,Murray-Hayden,E. (2001) Using fluorescence lifetime measurements to quantitatively characterise crude oils. IMOG 2001 International Meeting of Organic Geochemists. Conference Poster [Details]
(2001) The application of fluid inclusion studies to oil and gas exploration. Ireland's Deepwater Frontier: Results from the Petroleum Infrastructure Programme PIP.
Parnell, J.,Feely, M.,Ryder, A.,Murray-Hayden, E.,Glynn,T. (2001) The application of fluid inclusion studies to oil and gas exploration. Ireland's Deepwater Frontier: Results from the Petroleum Infrastructure Programme PIP. Conference Poster [Details]

Correction

  Year Publication
(2010) Application of fluorescence lifetime measurements on single petroleum-bearing fluid inclusions to demonstrate multicharge history in petroleum reservoirs (vol 9, pg 330, 2009).
Blamey, NJF,Conliffe, J,Parnell, J,Ryder, AG,Feely, M (2010) Application of fluorescence lifetime measurements on single petroleum-bearing fluid inclusions to demonstrate multicharge history in petroleum reservoirs (vol 9, pg 330, 2009). Correction [DOI] [Details]

Published abstracts

  Year Publication
(1999) Raman microscopy and the analysis of microscopic fluid inclusions. Supplement to proceedings of the royal microscopical society.
Ryder,A.G, Feely,M, Moran,R, O'Connor,G.M, Glynn,T.J. (1999) Raman microscopy and the analysis of microscopic fluid inclusions. Supplement to proceedings of the royal microscopical society. Published abstracts [Details]

Reviews

  Year Publication
(2005) Surface enhanced Raman scattering for narcotic detection and applications to chemical biology.
Ryder, AG (2005) Surface enhanced Raman scattering for narcotic detection and applications to chemical biology. Reviews [DOI] [Details]

Research Paper

  Year Publication
(2005) Analysis of hydrocarbon bearing fluid inclusions (HCFI) using time-resolved fluorescence spectroscopy.
Przyjalgowski,M.A.,Ryder,A.G.,Feely,M.,Glynn,T.J. (2005) Analysis of hydrocarbon bearing fluid inclusions (HCFI) using time-resolved fluorescence spectroscopy. Opto Ireland 2005, Published in: Proc SPIE - Int. Soc. Opt. Eng. vol. 5826: Research Paper [Details]

Professional Associations

  Association Function From / To
Society for Applied Spectroscopy Past Member 30-DEC-99 / 31-DEC-10
Microscopical Society of Ireland Public Relations Officer 30-DEC-99 / 18-JUN-09

Patents

  Patent Number Title Granted
US7,983,874B2 Similarity Index: a rapid classification method for multivariate data arrays 01-JAN-99

Committees

  Committee Function From / To
26th Annual Symposium of the Microscopical Society of Ireland Organiser 28-AUG-02 / 30-AUG-02
Opto-Ireland, SPIE regional meeting, Dublin Co-chair for Spectroscopy conference at Opto-Irela 04-APR-05 / 05-APR-05
Member of IUPAC committee for developing fluorescence standards /
Member of the Society for Applied Spectroscopy /
Member of the Editorial Board, Journal of Fluorescence /
Member of the Research committee and APRC sub groups of Governing Authority /
Opto-Ireland, SPIE regional meeting, Galway. Co-chaired Applications of Spectroscopy conference. 05-SEP-02 / 06-SEP-02
Research Committee, College of Science Ordinary member, representing School of Chemistry 01-JAN-12 /

Employment

  Employer Position From / To
National Centre for National University of Ireland, Galway Adjunct Lecturer 01-AUG-03 / 30-DEC-99
NUI Galway Senior Lecturer 01-AUG-06 /
National Centre for Biomedical Engineering Science SFI Investigator 01-AUG-03 / 30-DEC-99
University College Cork Postdoctoral Researcher 01-JAN-93 / 31-DEC-95
NUI, Galway Research fellow 01-JAN-97 / 31-DEC-03

Education

  Year Institution Qualification Subject
1989 NUI Galway BSc Chemistry
1994 NUI Galway PhD Chemistry

Teaching Interests

Undergraduate teaching:
  •     4th year lecture courses on:  Fluorescence Spectroscopy & Microscopy.
  •     3rd year lecture courses on:  Rotational and Vibrational spectroscopy, Quantum Chemistry, X-Ray Fluorescence, thermal
        analysis, and  techniques for surface analysis..
  •     2nd year lecture courses on:  Spectroscopy, Applied Spectroscopy, and Chemical Equilibrium.
  •     Course director for CH205:  Analytical and Environmental Chemistry.
  •     4th year undergraduate chemistry student research project supervision.
  •     Chemistry laboratory supervision of 1st, 2nd, and 3rd undergraduate students.


Postgraduate Teaching:  Currently supervising seven PhD students:

  1.   Y. Casamayou-Boucou (2015 - , Chemistry), IRC scholar: Anisotropy Resolved Multidimensional Emission Spectroscopy
      (ARMES) for quantification of protein aggregation
    .
     
     
  2.   C. van Zanten (2015 -, Chemistry), CAPES scholarship:  Study of protein-nanoparticle interactions using advanced fluorescence
      based approaches.

  3.   A. Memmo (2015 -, Chemistry), College of Science scholarship:  Impurity Profiling using Raman spectroscopy & Chemometrics.

  4.   M. Kyne (2012 - , Chemistry), IRC scholar.  Novel triazine fluorophores.

  5.   R. Groza (2012 - , Chemistry), IRC scholar.  EEM & Chemometrics of complex mixtures.

  6.   P. Zarski (2012 - , Chemistry), IRC scholar.  TIRF & protein/surface interactions.

  7.   M. Zakarul (2011-, Chemistry), Bangladeshi Gov. Scholar:  Analysis of biomedical polymers.


Recent Postgraduate Students

  Graduation Name Degree Primary Supervisor
2015 B. Kissane PhD Y
2014 M. Hennigan (Chemistry) PhD Y
2013 A. Calvet (Chemistry) PhD Y
2013 R. McCarthy (Chemistry) co-supervised with Prof. D. Leech PhD N
2012 C. Morris, (2007-11, Chemistry) PhD Y
2012 D. O'Shaughnessy, (2007-12, Chemistry) PhD Y
2010 P. Owens, (2006-10, Chemistry) PhD Y
2010 C.Y. Chong, M.Sc. (2006-09, Chemistry) Msc Y
2009 B. Szczupak, (2000-09, Physics) PhD Y
2009 M.-L. O' Connell, (2003-08, Chemistry) PhD Y
2011 R. Murray, (2004-10, Chemistry) PhD Y
2006 M. Przyjalgowski, (2000-05, Physics) PhD Y
2003 S. Power, (1999-2002, Physics) PhD Y
2006 S. Cawley, (2002-05, Physics) Msc Y
2006 J. Conroy, (2003-05, Chemistry) Msc Y
2004 E. Murray-Hayden, (2000-04, Geology) Msc

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
2nd year, SEM 1 Physical Chemistry CH203 6 lectures on spectroscopy & chemical equilibrium.
3rd year, SEM 1 Analytical Chemistry and Molecular Structure CH326 X-Ray Fluorescence, XPS, SEM, SIMS, and EDS (6 lectures)
3rd year, SEM 2 Physical Chemistry CH313 Spectroscopy (Raman, NIR, Rotational) and quantum chemistry (10 lectures).
4th year, SEM 1 Physical Chemistry CH449 Fluorescence spectroscopy (6 lectures).
4th year, SEM 2 Spectroscopy, Physical Methods, & Applications. CH448 6 lectures on fluorescence microscopy.
2nd Year, SEM 2 Analytical and Environmental Chemistry CH205 6 lectures on applied spectroscopy.

Internal Collaborators

  Name Description of Collaboration
Prof. Martin Feely
1998-2010, Spectroscopic analysis of petroleum fluids and hydrocarbon bearing fluid inclusions.
Dr. Y. Rotchev
2000-2010, Development of fluorescence based methods for the analysis of biomedical polymers, [see publication list for more details].
Dr. H.-P. Nasheuer
2003-2010: Fluorescence Correlation Spectroscopy (FCS) and Fluorescence Lifetime Imaging Microscopy (FLIM) of biological systems. [see publication list for more details].
Prof. P. Dockery
Studying the use of structured light illumination for fluid inclusion analysis.

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
Dr Leigh F. Jones Bangor University WALES
Dr. G. S. Papaefstathiou Laboratory of Inorganic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 157 71 Zogragfou. GREECE
Raman analysis of inorganic materials.
Dr. Kirk Leister Bristol-Myers Squibb, Syracuse, NY, U.S.A.
Development of novel bio-analytical methods. [see publication list for more details].
Dr. John Stephens Department of Chemistry, NUI, Maynooth IRELAND
Novel fluorophores produced by Dr. Stephens and his group are characterized photophysically in Galway.
Dr. A.S. Klymchenko Laboratoire de Pharmacologie et Physicochimie des interactions cellulaires et moleculaires, Faculte de Pharmacie, Universite Louis Pasteur, Illkirch, FRANCE
Use of ESIPT fluorophores for the measurement of polymer polarity and other physio-chemical parameters. [see publication list for more details].