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Chemistry

Prof Olivier Thomas

PhD

Contact Details

Est. Professor in Marine Biodiscovery
National University of Ireland Galway Marine Biodiscovery, School of Chemistry and Ryan Institute, College of Science, Room C212
University Road,
H91TK33 Galway
Ireland
T: +353(0)91493563
M: +33(0)674802384
E: olivier.thomas@nuigalway.ie
www.imbd.ie
 
researcher
 

Biography

2015-: Established Professor in Marine Biodiscovery at NUI Galway
2012: Professor in Marine Natural Product Chemistry at University Nice Sophia Antipolis, France
2004: Lecturer in Marine Natural Product Chemistry at University Nice Sophia Antipolis, France
2002: Post-Doctorate at CEA Saclay, France
2002: PhD in Organic Chemistry at University Paris Descartes, France
under the supervision of Henri-Philippe HUSSON
1999: Master Degree in Organic Chemistry from University Paris Descartes, France
1996-1998: Teacher at French School La Condamine Quito, Ecuador
1996: Agregation in Chemistry at Ecole Normale Superieure de Cachan, France

Research Interests

Our research focuses on the specialized metabolites, also called natural products, produced by marine organisms and especially marine invertebrates like sponges, zoantharians, soft corals but also algae, microalgae, or cyanobacteria. While our main playground for biodiscovery is the North-eastern Atlantic and especially the Irish waters from the seashore until the deep sea, through collaborations with local marine biologists and ecologists, we work in the Caribbean and Mediterranean Seas or the Atlantic and Pacific Oceans. See our website at www.imbd.ie
We have expertise in the purification by HPLC and structure elucidation by NMR and MS of all types of specialized metabolites. Such natural products may find applications in the pharmaceutical, the cosmetical or agri-food sectors. Through the establishment of a National Marine Biodiscovery Laboratory in Ireland we strive for a strong collaboration between marine biologists, taxonomists, microbiologists, and chemists to organize a biological and chemical repository of marine products. We are also engaged in several projects in marine chemical ecology first to understand their metabolic pathways but also their ecological role in the environment. Although omnipresent, the chemical mediation in the marine environment is still very poorly understood. We develop new tools to point out the key role of some chemical cues in the structure of ecosystems. These findings may also find applications in several sectors like the aquaculture sector. These approaches are of special interest in the field of marine biotoxins. Under the impacts of anthropogenic activities and global changes the proliferation of non-indigenous species and especially toxic dinoflagellates and cyanobacteria affect local ecosystems through the production and release of specialized metabolites. The marine seafood sector is frequently under the threat of such toxic contamination. To address these basic and applied questions we want to apply the recent technological and more global approach called marine environmental metabolomics by mass spectrometry but also nuclear magnetic resonance.

Keywords:  Natural Product Chemistry, Bioactive Natural Products, Chemical Ecology, Marine Invertebrates, Sponges, Microalgae, Metabolic Pathways, Metabolomics

Research Projects

  Project Start Date End Date
BIOMATERIALS REPOSITORY PROJECT - MI TENDER 01-JUL-20 30-JUN-26
PROGRESSING MARINE BIODISCOVERY IN IRELAND 01-MAR-20 28-FEB-25
CULLEN FELLOWSHIP - CULTURE OPTIMISATION, AND BIOACTIVITY OF SELECTED TOXIC IRISH MICROALGAE 01-OCT-18 30-SEP-21
A NATIONAL MARINE BIODISCOVERY LABORATORY 09-DEC-16 31-JUL-20
Olivier Thomas Research General Account 01-JAN-16 31-DEC-26
CÚRAM - MedTrain Co-fund - Olivier Thomas 01-JAN-15 31-DEC-20
MARINE CHIROPTICS 01-DEC-17 31-DEC-19
ALERTOX-NET (Interreg) 01-OCT-17 31-MAR-21
Registrars Office 01-NOV-15 31-OCT-20
OCEAN-15 04-JAN-16 31-DEC-19
TARA-PACIFIC 01-JUL-16 01-JUL-18

Contract Researchers

  Researcher Name Project Role Funding Body
Maggie REDDY Integrative taxonomy Postdoctoral researcher Marine Institute
Laurence JENNINGS NMBLI PostDoctorate Management of the project and marine natural product chemistry
Maria MIGUEL Sponges from the Tara Expedition PhD Hardiman
Sam AFOULLOUSS Deep Sea Marine Biodiscovery (Louise Allcock) PhD student cosupervised with Louise Allcock
Elliot MURPHY Toxic microalgae from Ireland PhD cosupervised with Joe Silke MI
Shauna O'BRIEN Chemical diversity of Irish toxic cyanobacteria PhD in chemistry NUI Galway
Caoimhe FITZGIBBON Chemical diversity of toxic cyanobacteria from New Caledonia MSc by research
Jordan BUCKLEY Irish marine natural products to fight degenerative diseases MSc by research

Peer Reviewed Journals

  Year Publication
(2020) 'A New Network for the Advancement of Marine Biotechnology in Europe and Beyond'
Rotter, Ana and Bacu, Ariola and Barbier, Michèle and Bertoni, Francesco and Bones, Atle M. and Cancela, M. Leonor and Carlsson, Jens and Carvalho, Maria F. and Cegłowska, Marta and Dalay, Meltem Conk and Dailianis, Thanos and Deniz, Irem and Drakulovic, Dragana and Dubnika, Arita and Einarsson, Hjörleifur and Erdoğan, Ayşegül and Eroldoğan, Orhan Tufan and Ezra, David and Fazi, Stefano and FitzGerald, Richard J. and Gargan, Laura M. and Gaudêncio, Susana P. and Ivošević DeNardis, Nadica and Joksimovic, Danijela and Kataržytė, Marija and Kotta, Jonne and Mandalakis, Manolis and Matijošytė, Inga and Mazur-Marzec, Hanna and Massa-Gallucci, Alexia and Mehiri, Mohamed and Nielsen, Søren Laurentius and Novoveská, Lucie and Overlingė, Donata and Portman, Michelle E. and Pyrc, Kr (2020) 'A New Network for the Advancement of Marine Biotechnology in Europe and Beyond'. Frontiers in Marine Science, 7 [DOI] [Details]
(2020) 'Insights into the Metabolome of the Cyanobacterium Leibleinia gracilis from the Lagoon of Tahiti and First Inspection of Its Variability'
Solanki, Hiren and Pierdet, Manon and Thomas, Olivier P. and Zubia, Mayalen (2020) 'Insights into the Metabolome of the Cyanobacterium Leibleinia gracilis from the Lagoon of Tahiti and First Inspection of Its Variability'. Metabolites, 10 (5) [DOI] [Details]
(2020) 'Impact of ocean acidification on the metabolome of the brown macroalgae Lobophora rosacea from New Caledonia'
Julie Gaubert and Riccardo Rodolfo-Metalpa and Stéphane Greff and Olivier P. Thomas and Claude E. Payri (2020) 'Impact of ocean acidification on the metabolome of the brown macroalgae Lobophora rosacea from New Caledonia'. Algal Research, 46 [DOI] [Details]
(2020) 'Efficient, fast and inexpensive bioassay to monitor benthic microalgae toxicity: Application to Ostreopsis species'
Anne-Sophie Pavaux and Eva Ternon and Louison Dufour and Sophie Marro and Marin-Pierre Gémin and Olivier P. Thomas and Rodolphe Lemée (2020) 'Efficient, fast and inexpensive bioassay to monitor benthic microalgae toxicity: Application to Ostreopsis species'. Aquatic Toxicology, 223 [DOI] [Details]
(2020) 'Metabolomic study of soft corals from the Colombian Caribbean: PSYCHE and 1H-NMR comparative analysis'
Santacruz, Liliana,Hurtado, Diana X.,Doohan, Roisin,Thomas, Olivier P.,Puyana, Mónica,Tello, Edisson (2020) 'Metabolomic study of soft corals from the Colombian Caribbean: PSYCHE and 1H-NMR comparative analysis'. Scientific Reports, 10 (1) [Details]
(2020) 'Specialized microbiome of the cave-dwelling sponge Plakina kanaky (Porifera, Homoscleromorpha)'
Ruiz, César and Villegas-Plazas, Marcela and Thomas, Olivier P and Junca, Howard and Pérez, Thierry (2020) 'Specialized microbiome of the cave-dwelling sponge Plakina kanaky (Porifera, Homoscleromorpha)'. FEMS Microbiology Ecology, 96 (4) [DOI] [Details]
(2020) 'Cytotoxic and Anti-Inflammatory Effects of Ent-Kaurane Derivatives Isolated from the Alpine Plant Sideritis hyssopifolia'
Aimond, Axelle and Calabro, Kevin and Audoin, Coralie and Olivier, Elodie and Dutot, Mélody and Buron, Pauline and Rat, Patrice and Laprévote, Olivier and Prado, Soizic and Roulland, Emmanuel and Thomas, Olivier P. and Genta-Jouve, Grégory (2020) 'Cytotoxic and Anti-Inflammatory Effects of Ent-Kaurane Derivatives Isolated from the Alpine Plant Sideritis hyssopifolia'. Molecules, 25 (3) [DOI] [Details]
(2020) 'A Novel High-Throughput Screening Platform Identifies Itaconate Derivatives from Marine Penicillium antarcticum as Inhibitors of Mesenchymal Stem Cell Differentiation'
Marchese, Pietro and Mahajan, Nipun and O’Connell, Enda and Fearnhead, Howard and Tuohy, Maria and Krawczyk, Janusz and Thomas, Olivier P. and Barry, Frank and Murphy, Mary J. (2020) 'A Novel High-Throughput Screening Platform Identifies Itaconate Derivatives from Marine Penicillium antarcticum as Inhibitors of Mesenchymal Stem Cell Differentiation'. Marine Drugs, 18 (4) [DOI] [Details]
(2019) 'Brominated Bisindole Alkaloids from the Celtic Sea Sponge Spongosorites calcicola'
Jennings, Laurence K. and Khan, Neyaz M. D. and Kaur, Navdeep and Rodrigues, Daniel and Morrow, Christine and Boyd, Aoife and Thomas, Olivier P. (2019) 'Brominated Bisindole Alkaloids from the Celtic Sea Sponge Spongosorites calcicola'. Molecules, 24 (21) [DOI] [Details]
(2019) 'Tara Pacific Expedition’s Atmospheric Measurements of Marine Aerosols across the Atlantic and Pacific Oceans: Overview and Preliminary Results'
Flores, J. M.,Bourdin, G.,Altaratz, O.,Trainic, M.,Lang-Yona, N.,Dzimban, E.,Steinau, S.,Tettich, F.,Planes, S.,Allemand, D.,Agostini, S.,Banaigs, B.,Boissin, E.,Boss, E.,Douville, E.,Forcioli, D.,Furla, P.,Galand, P. E.,Sullivan, M. B.,Gilson, É.,Lombard, F.,Moulin, C.,Pesant, S.,Poulain, J.,Reynaud, S.,Romac, S.,Sunagawa, S.,Thomas, O. P.,Troublé, R.,de Vargas, C.,Thurber, R. Vega,Voolstra, C. R.,Wincker, P.,Zoccola, D.,Bowler, C.,Gorsky, G.,Rudich, Y.,Vardi, A.,Koren, I. (2019) 'Tara Pacific Expedition’s Atmospheric Measurements of Marine Aerosols across the Atlantic and Pacific Oceans: Overview and Preliminary Results'. Bulletin of the American Meteorological Society, 101 (5) [Details]
(2019) 'Expanding Tara Oceans Protocols for Underway, Ecosystemic Sampling of the Ocean-Atmosphere Interface During Tara Pacific Expedition (2016–2018)'
Gorsky, Gabriel and Bourdin, Guillaume and Lombard, Fabien and Pedrotti, Maria Luiza and Audrain, Samuel and Bin, Nicolas and Boss, Emmanuel and Bowler, Chris and Cassar, Nicolas and Caudan, Loic and Chabot, Genevieve and Cohen, Natalie R. and Cron, Daniel and De Vargas, Colomban and Dolan, John R. and Douville, Eric and Elineau, Amanda and Flores, J. Michel and Ghiglione, Jean Francois and Haëntjens, Nils and Hertau, Martin and John, Seth G. and Kelly, Rachel L. and Koren, Ilan and Lin, Yajuan and Marie, Dominique and Moulin, Clémentine and Moucherie, Yohann and Pesant, Stéphane and Picheral, Marc and Poulain, Julie and Pujo-Pay, Mireille and Reverdin, Gilles and Romac, Sarah and Sullivan, Mathew B. and Trainic, Miri and Tressol, Marc and Troublé, Romain and Vardi, Assaf and Voolstra, (2019) 'Expanding Tara Oceans Protocols for Underway, Ecosystemic Sampling of the Ocean-Atmosphere Interface During Tara Pacific Expedition (2016–2018)'. Frontiers in Marine Science, 6 [DOI] [Details]
(2019) 'Genome Mining Coupled with OSMAC-Based Cultivation Reveal Differential Production of Surugamide A by the Marine Sponge Isolate Streptomyces sp. SM17 When Compared to Its Terrestrial Relative S. albidoflavus J1074'
Almeida, Eduardo L. and Kaur, Navdeep and Jennings, Laurence K. and Carrillo Rincón, Andrés Felipe and Jackson, Stephen A. and Thomas, Olivier P. and Dobson, Alan D.W. (2019) 'Genome Mining Coupled with OSMAC-Based Cultivation Reveal Differential Production of Surugamide A by the Marine Sponge Isolate Streptomyces sp. SM17 When Compared to Its Terrestrial Relative S. albidoflavus J1074'. Microorganisms, 7 (10) [DOI] [Details]
(2019) 'Chemical Insights into the Anchinopeptolide Series'
Bastos Lemos Silva, Siguara and Beniddir, Mehdi A. and Gallard, Jean-François and Poupon, Erwan and Thomas, Olivier P. and Evanno, Laurent (2019) 'Chemical Insights into the Anchinopeptolide Series'. European Journal of Organic Chemistry, 2019 (31-32):5515-5518 [DOI] [Details]
(2019) 'Potential of tropical macroalgae from French Polynesia for biotechnological applications'
Zubia, Mayalen,Thomas, Olivier P.,Soulet, Stéphanie,Demoy-Schneider, Marina,Saulnier, Denis,Connan, Solène,Murphy, Elliot C.,Tintillier, Florent,Stiger-Pouvreau, Valérie,Petek, Sylvain (2019) 'Potential of tropical macroalgae from French Polynesia for biotechnological applications'. Journal of Applied Phycology, [Details]
(2019) 'Chemical insights in the anchinopeptolide series'
Siguara Bastos Lemos; Silva Mehdi A Beniddir; Jean-François Gallard; Erwan Poupon; Olivier P Thomas; Laurent Evanno (2019) 'Chemical insights in the anchinopeptolide series'. European Journal Of Organic Chemistry, [Details]
(2019) 'The Tara Pacific expedition—A pan-ecosystemic approach of the “-omics” complexity of coral reef holobionts across the Pacific Ocean'
Planes, Serge AND Allemand, Denis AND Agostini, Sylvain AND Banaigs, Bernard AND Boissin, Emilie AND Boss, Emmanuel AND Bourdin, Guillaume AND Bowler, Chris AND Douville, Eric AND Flores, J. Michel AND Forcioli, Didier AND Furla, Paola AND Galand, Pierre E. AND Ghiglione, Jean-François AND Gilson, Eric AND Lombard, Fabien AND Moulin, Clémentine AND Pesant, Stephane AND Poulain, Julie AND Reynaud, Stéphanie AND Romac, Sarah AND Sullivan, Matthew B. AND Sunagawa, Shinichi AND Thomas, Olivier P. AND Troublé, Romain AND de Vargas, Colomban AND Vega Thurber, Rebecca AND Voolstra, Christian R. AND Wincker, Patrick AND Zoccola, Didier AND the Tara Pacific Consortium (2019) 'The Tara Pacific expedition—A pan-ecosystemic approach of the “-omics” complexity of coral reef holobionts across the Pacific Ocean'. PLOS Biology, 17 (9):1-14 [DOI] [Details]
(2019) 'Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra'
Miguel-Gordo, Maria and Gegunde, Sandra and Calabro, Kevin and Jennings, Laurence K. and Alfonso, Amparo and Genta-Jouve, Grégory and Vacelet, Jean and Botana, Luis M. and Thomas, Olivier P. (2019) 'Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra'. Marine Drugs, 17 (6) [DOI] [Details]
(2019) 'Effects of the toxic dinoflagellate Ostreopsis cf. ovata on survival, feeding and reproduction of a phytal harpacticoid copepod'
Pavaux Anne-Sophie and Rostan Julie and Guidi-Guilvard Laurence and Marro Sophie and Ternon Eva and Olivier P. Thomas and Lemée Rodolphe and Gasparini Stéphane (2019) 'Effects of the toxic dinoflagellate Ostreopsis cf. ovata on survival, feeding and reproduction of a phytal harpacticoid copepod'. Journal of Experimental Marine Biology and Ecology, 516 :103-113 [DOI] [Details]
(2019) 'Effects of the toxic dinoflagellate Ostreopsis cf. ovata on survival, feeding and reproduction of a phytal harpacticoid copepod'
Pavaux Anne-Sophie, Rostan Julie, Guidi-Guilvard Laurence, Marro Sophie, Ternon Eva, Olivier P. Thomas, Lemee Rodolphe, Gasparini Stephane (2019) 'Effects of the toxic dinoflagellate Ostreopsis cf. ovata on survival, feeding and reproduction of a phytal harpacticoid copepod'. Journal Of Experimental Marine Biology And Ecology, 516 :103-113 [DOI] [Details]
(2019) 'Comparative Analyses of Metabolomic Fingerprints and Cytotoxic Activities of Soft Corals from the Colombian Caribbean'
Santacruz, Liliana and Thomas, Olivier P. and Duque, Carmenza and Puyana, Mónica and Tello, Edisson (2019) 'Comparative Analyses of Metabolomic Fingerprints and Cytotoxic Activities of Soft Corals from the Colombian Caribbean'. Marine Drugs, 17 (1) [DOI] [Details]
(2019) 'Structure Elucidation and Biological Evaluation of Maitotoxin-3, a Homologue of Gambierone, from Gambierdiscus belizeanus'
Boente-Juncal, Andrea and Álvarez, Mercedes and Antelo, Álvaro and Rodríguez, Inés and Calabro, Kevin and Vale, Carmen and Thomas, Olivier P. and Botana, Luis M. (2019) 'Structure Elucidation and Biological Evaluation of Maitotoxin-3, a Homologue of Gambierone, from Gambierdiscus belizeanus'. Toxins, 11 (2) [DOI] [Details]
(2019) 'Inhibition of Leucoagaricus gongylophorus with Carica papaya: an alternative to control the leaf-cutter ant Acromyrmex octospinosus'
Tatiana Lobo-Echeverri and Víctor Manuel Galindo and Pilar Aubad and Adriana Ortiz-Reyes and Lina Maria Preciado and Mauricio Sánchez and James Jiménez and Olivier P. Thomas (2019) 'Inhibition of Leucoagaricus gongylophorus with Carica papaya: an alternative to control the leaf-cutter ant Acromyrmex octospinosus'. International Journal of Pest Management, 0 (0):1-14 [DOI] [Details]
(2019) 'Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra'
Miguel-Gordo, Maria; Gegunde, Sandra; Calabro, Kevin; Jennings, Laurence K.; Alfonso, Amparo; Genta-Jouve, Gregory; Vacelet, Jean; Botana, Luis M.; Thomas, Olivier P. (2019) 'Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra'. Marine Drugs, 17 (6) [DOI] [Details]
(2009) 'Hormigas (Hymenoptera: Formicidae) de Tabasco: explorando la diversidad de la mirmecofauna en las selvas tropicales de baja altitud [Ants (Hymenoptera: Formicidae) from Tabasco: exploring the myrmecofauna diversity in lowland tropical forests]'
del Toro I (2009) 'Hormigas (Hymenoptera: Formicidae) de Tabasco: explorando la diversidad de la mirmecofauna en las selvas tropicales de baja altitud [Ants (Hymenoptera: Formicidae) from Tabasco: exploring the myrmecofauna diversity in lowland tropical forests]'. Dugesiana (Spanish), 16 [Details]
(2019) 'Metabolomic variability of four macroalgal species of the genus Lobophora using diverse approaches'
Gaubert, Julie,Greff, Stephane,Thomas, Olivier P.,Payri, Claude E. (2019) 'Metabolomic variability of four macroalgal species of the genus Lobophora using diverse approaches'. Phytochemistry, 162 :165-172 [Details]
(2019) 'Structure Revision of Microginins 674 and 690 from the Cultured Cyanobacterium Microcystis aeruginosa'
Calabro, Kevin,Genta-Jouve, Gregory,Thomas, Olivier P. (2019) 'Structure Revision of Microginins 674 and 690 from the Cultured Cyanobacterium Microcystis aeruginosa'. Journal of Natural Products, [Details]
(2019) 'Insights into the Biosynthesis of Cyclic Guanidine Alkaloids from Crambeidae Marine Sponges'
Silva, Siguara B. L.,Oberhaensli, Francois,Tribalat, Marie-Aude,Genta-Jouve, Gregory,Teyssie, Jean-Louis,Dechraoui-Bottein, Marie-Yasmine,Gallard, Jean-Francois,Evanno, Laurent,Poupon, Erwan,Thomas, Olivier P. (2019) 'Insights into the Biosynthesis of Cyclic Guanidine Alkaloids from Crambeidae Marine Sponges'. Angewandte Chemie-International Edition In English, 58 (2):520-525 [Details]
(2019) 'Treasures from the Deep: Characellides as Anti-Inflammatory Lipoglycotripeptides from the Sponge Characella pachastrelloides'
Afoullouss, Sam,Calabro, Kevin,Genta-Jouve, Gregory,Gegunde, Sandra,Alfonso, Amparo,Nesbitt, Robert,Morrow, Christine,Alonso, Eva,Botana, Luis,Allcock, Louise,Thomas, Olivier P. (2019) 'Treasures from the Deep: Characellides as Anti-Inflammatory Lipoglycotripeptides from the Sponge Characella pachastrelloides'. Organic Letters, 21 (1):246-251 [Details]
(2018) 'Stereochemical Study of Puna'auic Acid, an Allenic Fatty Acid from the Eastern Indo-Pacific Cyanobacterium Pseudanabaena sp'
Roulland, Emmanuel,Solanki, Hiren,Calabro, Kevin,Zubia, Mayalen,Genta-Jouve, Gregory,Thomas, Olivier P. (2018) 'Stereochemical Study of Puna'auic Acid, an Allenic Fatty Acid from the Eastern Indo-Pacific Cyanobacterium Pseudanabaena sp'. Organic Letters, 20 (8):2311-2314 [Details]
(2018) 'Suberitane sesterterpenoids from the Antarctic sponge Phorbas areolatus (Thiele, 1905)'
Solanki, Hiren,Angulo-Preckler, Carlos,Calabro, Kevin,Kaur, Navdeep,Lasserre, Perrine,Cautain, Bastien,de la Cruz, Mercedes,Reyes, Fernando,Avila, Conxita,Thomas, Olivier P. (2018) 'Suberitane sesterterpenoids from the Antarctic sponge Phorbas areolatus (Thiele, 1905)'. Tetrahedron Letters, 59 (36):3353-3356 [Details]
(2018) 'Distance interaction between marine cave-dwelling sponges and crustaceans'
Santonja, Mathieu,Greff, Stephane,Le Croller, Marie,Thomas, Olivier P.,Perez, Thierry. (2018) 'Distance interaction between marine cave-dwelling sponges and crustaceans'. Marine Biology (Heidelberg, Germany), 165 (7):1-15 [Details]
(2018) 'Marine invasive macroalgae: Turning a real threat into a major opportunity - the biotechnological potential of Sargassum muticum and Asparagopsis armata'
Pinteus, Susete,Lemos, Marco F.L.,Alves, Celso,Neugebauer, Agnieszka,Silva, Joana,Thomas, Olivier P.,Botana, Luis M.,Gaspar, Helena,Pedrosa, Rui (2018) 'Marine invasive macroalgae: Turning a real threat into a major opportunity - the biotechnological potential of Sargassum muticum and Asparagopsis armata'. Algal Research, 34 :217-234 [Details]
(2018) 'Variations in Microbial Diversity and Metabolite Profiles of the Tropical Marine Sponge Xestospongia muta with Season and Depth'
Villegas-Plazas, Marcela,Wos-Oxley, Melissa L.,Sanchez, Juan A.,Pieper, Dietmar H.,Thomas, Olivier P.,Junca, Howard. (2018) 'Variations in Microbial Diversity and Metabolite Profiles of the Tropical Marine Sponge Xestospongia muta with Season and Depth'. Microbial Ecology, [Details]
(2018) 'Unusual polycyclic fused product by oxidative enzymatic dimerisation of 5-methylpyrogallol catalyzed by horseradish peroxidase/H2O2'
Bouges, Helene,Calabro, Kevin,Thomas, Olivier P.,Antoniotti, Sylvain. (2018) 'Unusual polycyclic fused product by oxidative enzymatic dimerisation of 5-methylpyrogallol catalyzed by horseradish peroxidase/H2O2'. Molecules, 23 (10) [Details]
(2018) 'Metabolome variability for two Mediterranean sponge species of the genus Haliclona: specificity, time, and space'
Reverter, Miriam,Tribalat, Marie-Aude,Perez, Thierry,Thomas, Olivier P. (2018) 'Metabolome variability for two Mediterranean sponge species of the genus Haliclona: specificity, time, and space'. Metabolomics, 14 (9):1-12 [Details]
(2018) 'Allelopathic interactions between the benthic toxic dinoflagellate Ostreopsis cf. ovata and a co-occurring diatom'
Ternon, Eva,Pavaux, Anne-Sophie,Marro, Sophie,Thomas, Olivier P.,Lemee, Rodolphe (2018) 'Allelopathic interactions between the benthic toxic dinoflagellate Ostreopsis cf. ovata and a co-occurring diatom'. Harmful Algae, 75 :35-44 [Details]
(2018) 'Marine sponges as a powerful tool for trace elements biomonitoring studies in coastal environment'
Orani, Anna Maria,Barats, Aurelie,Vassileva, Emilia,Thomas, Olivier P. (2018) 'Marine sponges as a powerful tool for trace elements biomonitoring studies in coastal environment'. Marine Pollution Bulletin, 131 :633-645 [Details]
(2018) 'Comparative study on the bioaccumulation and biotransformation of arsenic by some northeastern Atlantic and northwestern Mediterranean sponges'
Orani, Anna Maria,Barats, Aurelie,Zitte, Wendy,Morrow, Christine,Thomas, Olivier P. (2018) 'Comparative study on the bioaccumulation and biotransformation of arsenic by some northeastern Atlantic and northwestern Mediterranean sponges'. Chemosphere, 201 :826-839 [Details]
(2017) 'Poecillastrosides, steroidal saponins from the mediterranean deep-sea sponge Poecillastra compressa (Bowerbank, 1866)'
Calabro, Kevin,Kalahroodi, Elaheh Lotfi,Rodrigues, Daniel,Diaz, Caridad,Cruz, Mercedes de la,Cautain, Bastien,Laville, Remi,Reyes, Fernando,Perez, Thierry,Soussi, Bassam,Thomas, Olivier P. (2017) 'Poecillastrosides, steroidal saponins from the mediterranean deep-sea sponge Poecillastra compressa (Bowerbank, 1866)'. Marine Drugs, 15 (7):1-12 [Details]
(2017) 'How environmental factors affect the production of guanidine alkaloids by the mediterranean sponge Crambe crambe'
Ternon, Eva,Perino, Erica,Manconi, Renata,Pronzato, Roberto,Thomas, Olivier P. (2017) 'How environmental factors affect the production of guanidine alkaloids by the mediterranean sponge Crambe crambe'. Marine Drugs, 15 (6) [Details]
(2017) 'Introducing the 2016 CASMI contest'
Genta-Jouve, Gregory, Thomas, Olivier P., Schymanski, Emma L.,Neumann, Steffen (2017) 'Introducing the 2016 CASMI contest'. Phytochemistry Letters, 21 (Supplement C) [Details]
(2017) 'The Marine Guanidine Alkaloid Crambescidin 816 Induces Calcium Influx and Cytotoxicity in Primary Cultures of Cortical Neurons through Glutamate Receptors'
Mendez, Aida G.,Juncal, Andrea Boente,Silva, Siguara B. L.,Thomas, Olivier P.,Martin Vazquez, Victor,Alfonso, Amparo,Vieytes, Mercedes R.,Vale, Carmen,Botana, Luis M. (2017) 'The Marine Guanidine Alkaloid Crambescidin 816 Induces Calcium Influx and Cytotoxicity in Primary Cultures of Cortical Neurons through Glutamate Receptors'. ACS Chemical Neuroscience, 8 (7):1609-1617 [Details]
(2017) 'Evaluation of the Protective Effects of Sarains on H2O2-Induced Mitochondrial Dysfunction and Oxidative Stress in SH-SY5Y Neuroblastoma Cells'
Alvarino, Rebeca,Alonso, Eva,Tribalat, Marie-Aude,Gegunde, Sandra,Thomas, Olivier P.,Botana, Luis M. (2017) 'Evaluation of the Protective Effects of Sarains on H2O2-Induced Mitochondrial Dysfunction and Oxidative Stress in SH-SY5Y Neuroblastoma Cells'. Neurotoxicity Research, 32 (3):368-380 [Details]
(2017) 'Isoguanosine derivatives from the Northeastern Atlantic sponge Clathria (Microciona) strepsitoxa'
Firsova, Daria,Calabro, Kevin,Lasserre, Perrine,Reyes, Fernando,Thomas, Olivier P. (2017) 'Isoguanosine derivatives from the Northeastern Atlantic sponge Clathria (Microciona) strepsitoxa'. Tetrahedron Letters, 58 (49):4652-4654 [Details]
(2017) 'N-Didehydrotyrosine identified from the Northeastern Atlantic marine sponge Hymeniacidon perlevis after Chemical Screening'
Nipun Mahajan, Kevin Calabro, Christine Morrow, Olivier P Thomas (2017) 'N-Didehydrotyrosine identified from the Northeastern Atlantic marine sponge Hymeniacidon perlevis after Chemical Screening'. Natural Product Communications, 12 [Details]
(2017) 'Poecillastrosides, Steroidal Saponins from the Mediterranean Deep-Sea Sponge Poecillastra compressa (Bowerbank, 1866)'
Calabro, K.; Kalahroodi, E.L.; Rodrigues, D.; Díaz, C.; Cruz, M.; Cautain, B.; Laville, R.; Reyes, F.; Pérez, T.; Soussi, B.; Thomas, O.P. (2017) 'Poecillastrosides, Steroidal Saponins from the Mediterranean Deep-Sea Sponge Poecillastra compressa (Bowerbank, 1866)'. Marine Drugs, 15 [DOI] [Details]
(2017) 'Bio-invasive ascidians in Ireland: A threat for the shellfish industry but also a source of high added value products'
Satheesh Kumar Palanisamy, Olivier P. Thomas & Grace P. McCormack (2017) 'Bio-invasive ascidians in Ireland: A threat for the shellfish industry but also a source of high added value products'. Bioengineered, [DOI] [Details]
(2017) 'Discrimination of Four Marine Biofilm-Forming Bacteria by LC-MS Metabolomics and Influence of Culture Parameters'
Favre, Laurie,Ortalo-Magne, Annick,Greff, Stephane,Perez, Thierry,Thomas, Olivier Paul,Martin, Jean-Charles,Culioli, Gerald. (2017) 'Discrimination of Four Marine Biofilm-Forming Bacteria by LC-MS Metabolomics and Influence of Culture Parameters'. Journal of Proteome Research, [Details]
(2017) 'Isolation and synthesis of pygmanilines, phenylurea derivatives from the Northeastern Atlantic lichen Lichina pygmaea'
Mahajan, Nipun,Chadda, Rekha,Calabro, Kevin,Solanki, Hiren,O'Connell, Enda,Murphy, Paul V.,Thomas, Olivier P. (2017) 'Isolation and synthesis of pygmanilines, phenylurea derivatives from the Northeastern Atlantic lichen Lichina pygmaea'. Tetrahedron Letters, 58 (12):1237-1239 [Details]
(2017) 'The interaction between the proliferating macroalga Asparagopsis taxiformis and the coral Astroides calycularis induces changes in microbiome and metabolomic fingerprints'
Greff, Stephane,Aires, Tania,Serrao, Ester A.,Engelen, Aschwin H.,Thomas, Olivier P.,Perez, Thierry. (2017) 'The interaction between the proliferating macroalga Asparagopsis taxiformis and the coral Astroides calycularis induces changes in microbiome and metabolomic fingerprints'. Scientific Reports, 7 [Details]
(2017) 'Chemogeography of the red macroalgae Asparagopsis: metabolomics, bioactivity, and relation to invasiveness'
Greff, Stephane,Zubia, Mayalen,Payri, Claude,Thomas, Olivier P.,Perez, Thierry. (2017) 'Chemogeography of the red macroalgae Asparagopsis: metabolomics, bioactivity, and relation to invasiveness'. Metabolomics, 13 (4):1-13 [Details]
(2017) 'Biological activities associated to the chemodiversity of the brown algae belonging to genus Lobophora (Dictyotales, Phaeophyceae)'
Vieira, Christophe,Gaubert, Julie,De Clerck, Olivier,Payri, Claude,Culioli, Gerald,Thomas, Olivier P. (2017) 'Biological activities associated to the chemodiversity of the brown algae belonging to genus Lobophora (Dictyotales, Phaeophyceae)'. Phytochemistry Reviews, 16 :1-17 [Details]
(2017) 'Autumnalamide targeted proteins of the immunophilin family'
Sanchez, Jon Andoni,Alfonso, Amparo,Thomas, Olivier P.,Botana, Lui­s M. (2017) 'Autumnalamide targeted proteins of the immunophilin family'. Immunobiology, 222 (2):241-250 [DOI] [Details]
(2016) 'Spherulization as a process for the exudation of chemical cues by the encrusting sponge C. crambe'
Eva Ternon, Lina Zarate, Sandrine Chenesseau, Julie Croué, Rémi Dumollard, Marcelino T. Suzuki & Olivier P. Thomas (2016) 'Spherulization as a process for the exudation of chemical cues by the encrusting sponge C. crambe'. Scientific Reports, 6 [ARAN Link] [Details]
(2016) 'Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model'
María Roel, Juan A. Rubiolo, Jorge Guerra-Varela, Siguara B. L. Silva, Olivier P. Thomas, Pablo Cabezas-Sainz, Laura Sánchez, Rafael López, Luis M. Botana (2016) 'Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model'. Oncotarget, 7 (50):83071-83087 [DOI] [Details]
(2016) 'Does the Chemical Diversity of the Order Haplosclerida (Phylum Porifera: Class Demospongia) Fit with Current Taxonomic Classification?'
Tribalat, Marie-Aude,Marra, Maria V.,McCormack, Grace P.,Thomas, Olivier P. (2016) 'Does the Chemical Diversity of the Order Haplosclerida (Phylum Porifera: Class Demospongia) Fit with Current Taxonomic Classification?'. Planta Medica, 82 (9-10):843-856 [ARAN Link] [Details]
(2016) 'Metabolomics for the Authentication of Natural Extracts Used in Flavours and Fragrances: the Case Study of Violet Leaf Absolutes from Viola odorata'
Saint-Lary L;Roy C;Paris JP;Martin JF;Thomas OP;Fernandez X; (2016) 'Metabolomics for the Authentication of Natural Extracts Used in Flavours and Fragrances: the Case Study of Violet Leaf Absolutes from Viola odorata'. Chemistry & biodiversity, 13 (6):737-747 [DOI] [Details]
(2016) 'Allelopathic interactions between the brown algal genus Lobophora (Dictyotales, Phaeophyceae) and scleractinian corals'
Vieira, Christophe,Thomas, Olivier P.,Culioli, Gerald,Genta-Jouve, Gregory,Houlbreque, Fanny,Gaubert, Julie,De Clerck, Olivier,Payri, Claude E. (2016) 'Allelopathic interactions between the brown algal genus Lobophora (Dictyotales, Phaeophyceae) and scleractinian corals'. Scientific Reports, 6 [ARAN Link] [Details]
(2016) 'Metabolomics as a tool for the authentication of rose extracts used in flavour and fragrance area'
Saint-Lary, Laure,Roy, Celine,Paris, Jean-Philippe,Martin, Jean-Francois,Thomas, Olivier P.,Fernandez, Xavier. (2016) 'Metabolomics as a tool for the authentication of rose extracts used in flavour and fragrance area'. Metabolomics, 12 (3):1-11 [Details]
(2016) 'On the use of 31P NMR for the quantification of hydrosoluble phosphorus-containing compounds in coral host tissues and cultured zooxanthellae'
Godinot, Claire,Gaysinski, Marc,Thomas, Olivier P.,Ferrier-Pages, Christine,Grover, Renaud. (2016) 'On the use of 31P NMR for the quantification of hydrosoluble phosphorus-containing compounds in coral host tissues and cultured zooxanthellae'. Scientific Reports, 6 [ARAN Link] [Details]
(2016) 'Gersemiols A-“C and Eunicellol A, Diterpenoids from the Arctic Soft Coral Gersemia fruticosa'
Angulo-Preckler, Carlos,Genta-Jouve, Grégory,Mahajan, Nipun,de la Cruz, Mercedes,de Pedro, Nuria,Reyes, Fernando,Iken, Katrin,Avila, Conxita,Thomas, Olivier P. (2016) 'Gersemiols A-“C and Eunicellol A, Diterpenoids from the Arctic Soft Coral Gersemia fruticosa'. Journal Of Natural Products, 79 :1132-1139 [Details]
(2015) 'Speciation of americium in seawater and accumulation in the marine sponge Aplysina cavernicola'
Maloubier, Melody,Michel, Herve,Solari, Pier Lorenzo,Moisy, Philippe,Tribalat, Marie-Aude,Oberhaensli, Francois R.,Dechraoui Bottein, Marie Yasmine,Thomas, Olivier P.,Monfort, Marguerite,Moulin, Christophe,Den Auwer, Christophe. (2015) 'Speciation of americium in seawater and accumulation in the marine sponge Aplysina cavernicola'. Dalton Transactions, 44 (47):20584-20596 [Details]
(2015) 'Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cells'
Fiorini, Laura,Sauvard, Lucy,Cazareth, Julie,Lalli, Enzo,Mus-Veteau, Isabelle,Tribalat, Marie-Aude,Sauvard, Lucy,Thomas, Olivier P.,Broutin, Isabelle,Thomas, Olivier P. (2015) 'Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cells'. Oncotarget, 6 (26):22282-22297 [Details]
(2015) 'Extraction, Purification, and NMR Analysis of Terpenes from Brown Algae'
Gaysinski, Marc,Ortalo-Magne, Annick,Thomas, Olivier P.,Culioli, Gerald (2015) 'Extraction, Purification, and NMR Analysis of Terpenes from Brown Algae'. Methods in molecular biology (Clifton, N.J.), 1308 :207-23 [Details]
(2015) 'Crambescin C1 Exerts a Cytoprotective Effect on HepG2 Cells through Metallothionein Induction'
Roel, Maria,Rubiolo, Juan A.,Botana, Luis M.,Ternon, Eva,Thomas, Olivier P.,Thomas, Olivier P.,Vieytes, Mercedes R. (2015) 'Crambescin C1 Exerts a Cytoprotective Effect on HepG2 Cells through Metallothionein Induction'. Marine drugs, 13 (8):4633-53 [Details]
(2015) 'Indole alkaloids from the Marquesan plant Rauvolfia nukuhivensis and their effects on ion channels'
Martin, Nicolas J.,Ferreiro, Sara F.,Barbault, Florent,Nicolas, Mael,Lecellier, Gael,Paetz, Christian,Gaysinski, Marc,Alonso, Eva,Thomas, Olivier P.,Botana, Luis M.,Raharivelomanana, Phila. (2015) 'Indole alkaloids from the Marquesan plant Rauvolfia nukuhivensis and their effects on ion channels'. Phytochemistry (Elsevier), 109 :84-95 [Details]
(2015) 'Antitumor and antimicrobial potential of bromoditerpenes isolated from the red alga, Sphaerococcus coronopifolius'
Rodrigues, Daniel,Alves, Celso,Horta, Andre,Pinteus, Susete,Silva, Joana,Culioli, Gerald,Thomas, Olivier P.,Pedrosa, Rui. (2015) 'Antitumor and antimicrobial potential of bromoditerpenes isolated from the red alga, Sphaerococcus coronopifolius'. Marine Drugs, 13 (2) [Details]
(2015) 'Gambierone, a Ladder-Shaped Polyether from the Dinoflagellate Gambierdiscus belizeanus'
Rodriguez, Ines,Genta-Jouve, Gregory,Alfonso, Carmen,Calabro, Kevin,Alonso, Eva,Sanchez, Jon A.,Alfonso, Amparo,Thomas, Olivier P.,Botana, Luis M. (2015) 'Gambierone, a Ladder-Shaped Polyether from the Dinoflagellate Gambierdiscus belizeanus'. Organic Letters, 17 (10):2392-2395 [Details]
(2015) 'Cystophloroketals A-E, unusual phloroglucinol-meroterpenoid hybrids from the brown alga Cystoseira tamariscifolia'
El Hattab, Mohamed,Genta-Jouve, Gregory,Bouzidi, Naima,Ortalo-Magne, Annick,Hellio, Claire,Marechal, Jean-Philippe,Piovetti, Louis,Thomas, Olivier P.,Culioli, Gerald. (2015) 'Cystophloroketals A-E, unusual phloroglucinol-meroterpenoid hybrids from the brown alga Cystoseira tamariscifolia'. Journal of Natural Products, 78 (7):1663-1670 [Details]
(2015) 'Metabolomic profiling reveals deep chemical divergence between two morphotypes of the zoanthid Parazoanthus axinellae'
Cachet, Nadja,Genta-Jouve, Gregory,Ivanisevic, Julijana,Chevaldonne, Pierre,Sinniger, Frederic,Culioli, Gerald,Perez, Thierry,Thomas, Olivier P. (2015) 'Metabolomic profiling reveals deep chemical divergence between two morphotypes of the zoanthid Parazoanthus axinellae'. Scientific Reports, 5 [Details]
(2015) 'Eryloside W, a triterpenoid saponin from the sponge Dictyonella marsilii'
Genta-Jouve, Gregory,Boughanem, Cecile,Ocana, Oscar,Perez, Thierry,Thomas, Olivier P. (2015) 'Eryloside W, a triterpenoid saponin from the sponge Dictyonella marsilii'. Phytochemistry Letters, 13 :252-255 [Details]
(2014) 'Autumnalamide, a Prenylated Cyclic Peptide from the Cyanobacterium Phormidium autumnale, Acts on SH-SY5Y Cells at the Mitochondrial Level'
Audoin, Coralie,Sanchez, Jon Andoni,Genta-Jouve, Gregory,Alfonso, Amparo,Rios, Laurent,Vale, Carmen,Thomas, Olivier P.,Botana, Luis M. (2014) 'Autumnalamide, a Prenylated Cyclic Peptide from the Cyanobacterium Phormidium autumnale, Acts on SH-SY5Y Cells at the Mitochondrial Level'. Journal of Natural Products, 77 (10):2196-2205 [Details]
(2014) 'Mahorones, highly brominated cyclopentenones from the red alga Asparagopsis taxiformis'
Greff, Stephane,Zubia, Mayalen,Genta-Jouve, Gregory,Massi, Lionel,Perez, Thierry,Thomas, Olivier P. (2014) 'Mahorones, highly brominated cyclopentenones from the red alga Asparagopsis taxiformis'. Journal of Natural Products, 77 (5):1150-1155 [Details]
(2014) 'Volatile Compounds of Viola odorata Absolutes: Identification of Odorant Active Markers to Distinguish Plants Originating from France and Egypt'
Saint-Lary, Laure,Roy, Celine,Paris, Jean-Philippe,Tournayre, Pascal,Berdague, Jean-Louis,Thomas, Olivier P.,Fernandez, Xavier. (2014) 'Volatile Compounds of Viola odorata Absolutes: Identification of Odorant Active Markers to Distinguish Plants Originating from France and Egypt'. Chemistry & Biodiversity, 11 (6):843-860 [Details]
(2014) 'Metabolome consistency: additional parazoanthines from the Mediterranean zoanthid Parazoanthus axinellae'
Audoin, Coralie,Cocandeau, Vincent,Thomas, Olivier P.,Bruschini, Adrien,Holderith, Serge,Genta-Jouve, Gregory. (2014) 'Metabolome consistency: additional parazoanthines from the Mediterranean zoanthid Parazoanthus axinellae'. Metabolites, 4 (2) [Details]
(2014) 'Further insights into brevetoxin metabolism by de Novo radiolabeling'
Calabro, Kevin,Guigonis, Jean-Marie,Teyssie, Jean-Louis,Oberhaensli, Francois,Goudour, Jean-Pierre,Warnau, Michel,Bottein, Marie-Yasmine Dechraoui,Thomas, Olivier P. (2014) 'Further insights into brevetoxin metabolism by de Novo radiolabeling'. Toxins, 6 (6) [Details]
(2014) 'Development of a work-flow for high-performance thin-layer chromatography data processing for untargeted metabolomics'
Audoin, Coralie,Holderith, Serge,Romari, Khadidja,Thomas, Olivier P.,Genta-Jouve, Gregory. (2014) 'Development of a work-flow for high-performance thin-layer chromatography data processing for untargeted metabolomics'. Journal of Planar Chromatography--Modern TLC, 27 (5):328-332 [Details]
(2014) 'Two-dimensional ultra high pressure liquid chromatography quadrupole/time-of-flight mass spectrometry for semi-targeted natural compounds identification'
Genta-Jouve, Gregory,Croue, Julie,Weinberg, Lionel,Cocandeau, Vincent,Holderith, Serge,Bontemps, Nataly,Suzuki, Marcelino,Thomas, Olivier P. (2014) 'Two-dimensional ultra high pressure liquid chromatography quadrupole/time-of-flight mass spectrometry for semi-targeted natural compounds identification'. Phytochemistry Letters, 10 :318-323 [Details]
(2014) 'Environmental solutions for the sustainable production of bioactive natural products from the marine sponge Crambe crambe'
Perez-Lopez, Paula,Ternon, Eva,Gonzalez-Garcia, Sara,Genta-Jouve, Gregory,Feijoo, Gumersindo,Thomas, Olivier P.,Moreira, Teresa. (2014) 'Environmental solutions for the sustainable production of bioactive natural products from the marine sponge Crambe crambe'. Science of the Total Environment, 475 :71-82 [Details]
(2014) 'In vitro antiplasmodial activity, cytotoxicity and chemical profiles of sponge species of Cuban coasts'
Mendiola, Judith,Regalado, Erik L.,Diaz-Garcia, Alexis,Thomas, Olivier P.,Fernandez-Calienes, Ayme,Rodriguez, Hermis,Laguna, Abilio,Valdes, Olga. (2014) 'In vitro antiplasmodial activity, cytotoxicity and chemical profiles of sponge species of Cuban coasts'. Natural Product Research, 28 (5):312-317 [Details]
(2013) 'Ulososides and urabosides - triterpenoid saponins from the Caribbean marine sponge Ectyoplasia ferox'
Colorado, Jhonny,Munoz, Diana,Marquez, Diana,Marquez, Maria Elena,Lopez, Juan,Thomas, Olivier P.,Martinez, Alejandro. (2013) 'Ulososides and urabosides - triterpenoid saponins from the Caribbean marine sponge Ectyoplasia ferox'. Molecules, 18 :2598-2610 [Details]
(2013) 'Sustainable production of biologically active molecules of marine based origin'
Murray, Patrick M.,Moane, Siobhan,Collins, Catherine,Beletskaya, Tanya,Thomas, Olivier P.,Duarte, Alysson W. F.,Nobre, Fernando S.,Owoyemi, Ifeloju O.,Pagnocca, Fernando C.,Sette, L. D.,McHugh, Edward,Causse, Eric,Perez-Lopez, Paula,Feijoo, Gumersindo,Moreira, .T.,Rubiolo, Juan,Leiros, Marta,Botana, Luis M.,Pinteus, Susete,Alves, Celso,Horta, Andre,Pedrosa, Rui,Jeffryes, Clayton,Agathos, Spiros N.,Allewaert, Celine,Verween, Annick,Vyverman, Wim,Laptev, Ivan,Sineoky, Sergei,Bisio, Angela,Manconi, Renata,Ledda, Fabio,Marchi, Mario,Pronzato, Roberto,Walsh, Daniel J. (2013) 'Sustainable production of biologically active molecules of marine based origin'. New Biotechnology, 30 (6):839-850 [Details]
(2013) 'Ligerin, an Antiproliferative Chlorinated Sesquiterpenoid from a Marine-Derived Penicillium Strain'
Vansteelandt, Marieke,Blanchet, Elodie,Egorov, Maxim,Petit, Fabien,Toupet, Loic,Bondon, Arnaud,Monteau, Fabrice,Le Bizec, Bruno,Thomas, Olivier P.,Pouchus, Yves Francois,Le Bot, Ronan,Grovel, Olivier. (2013) 'Ligerin, an Antiproliferative Chlorinated Sesquiterpenoid from a Marine-Derived Penicillium Strain'. Journal of Natural Products, 76 (2):297-301 [Details]
(2013) 'Absolute configuration of the new 3-epi-cladocroic acid from the Mediterranean sponge Haliclona fulva'
Genta-Jouve, Gregory,Thomas, Olivier P. (2013) 'Absolute configuration of the new 3-epi-cladocroic acid from the Mediterranean sponge Haliclona fulva'. Metabolites, 3 (1):24-32 [Details]
(2013) 'Differential Effects of Crambescins and Crambescidin 816 in Voltage-Gated Sodium, Potassium and Calcium Channels in Neurons'
Martin, Victor,Vale, Carmen,Bondu, Stephanie,Thomas, Olivier P.,Vieytes, Mercedes R.,Botana, Luis M. (2013) 'Differential Effects of Crambescins and Crambescidin 816 in Voltage-Gated Sodium, Potassium and Calcium Channels in Neurons'. Chemical Research in Toxicology, 26 (1):169-178 [Details]
(2013) 'Revising the Absolute Configurations of Coatlines via Density Functional Theory Calculations of Electronic Circular Dichroism Spectra'
Genta-Jouve, Gregory,Weinberg, Lionel,Cocandeau, Vincent,Maestro, Yannick,Thomas, Olivier Paul,Holderith, Serge. (2013) 'Revising the Absolute Configurations of Coatlines via Density Functional Theory Calculations of Electronic Circular Dichroism Spectra'. Chirality, 25 (3):180-184 [Details]
(2013) 'Balibalosides, an original family of glucosylated sesterterpenes produced by the Mediterranean sponge Oscarella balibaloi'
Audoin, Coralie,Bonhomme, Dominique,Ivanisevic, Julijana,de, la Cruz Mercedes,Cautain, Bastien,Monteiro, Maria Candida,Reyes, Fernando,Rios, Laurent,Perez, Thierry,Thomas, Olivier P. (2013) 'Balibalosides, an original family of glucosylated sesterterpenes produced by the Mediterranean sponge Oscarella balibaloi'. Marine drugs, 11 (5):1477-89 [Details]
(2013) 'Balibalosides, an original family of glycosylated sesterterpenes produced by the Mediterranean sponge Oscarella balibaloi'
Audoin, Coralie,Bonhomme, Dominique,Ivanisevic, Julijana,de la Cruz, Mercedes,Cautain, Bastien,Monteiro, Maria Candida,Reyes, Fernando,Rios, Laurent,Perez, Thierry,Thomas, Olivier P. (2013) 'Balibalosides, an original family of glycosylated sesterterpenes produced by the Mediterranean sponge Oscarella balibaloi'. Marine Drugs, 11 :1477-1489 [Details]
(2013) 'Additional Cytotoxic Pyridoacridine Alkaloids from the Ascidian Cystodytes violatinctus and Biogenetic Considerations'
Bontemps, Nataly,Gattacceca, Florence,Long, Christophe,Thomas, Olivier P.,Banaigs, Bernard. (2013) 'Additional Cytotoxic Pyridoacridine Alkaloids from the Ascidian Cystodytes violatinctus and Biogenetic Considerations'. Journal of Natural Products, 76 (9):1801-1805 [Details]
(2013) 'Biosynthesis in marine sponges: the radiolabelling strikes back'
Genta-Jouve, Gregory,Thomas, Olivier P. (2013) 'Biosynthesis in marine sponges: the radiolabelling strikes back'. Phytochemistry Reviews, 12 (3):425-434 [Details]
(2013) 'Crambescidin-816 acts as a fungicidal with more potency than crambescidin-800 and -830, inducing cell cycle arrest, increased cell size and apoptosis in Saccharomyces cerevisiae'
Rubiolo, Juan A.,Ternon, Eva,Lopez-Alonso, Henar,Thomas, Olivier P.,Vega, Felix V.,Vieytes, Mercedes R.,Botana, Luis M. (2013) 'Crambescidin-816 acts as a fungicidal with more potency than crambescidin-800 and -830, inducing cell cycle arrest, increased cell size and apoptosis in Saccharomyces cerevisiae'. Marine Drugs, 11 (11) [Details]
(2013) 'Chemical diversity in the scleractinian coral Astroides calycularis'
Cachet, Nadja,Loffredo, Loic,Vicente, Oscar Ocana,Thomas, Olivier P. (2013) 'Chemical diversity in the scleractinian coral Astroides calycularis'. Phytochemistry Letters, 6 (2):205-208 [Details]
(2012) 'Nukuhivensiums, indolo[2,3-a]quinoliziniums from the Marquesan plant Rauvolfia nukuhivensis'
Martin, Nicolas J.,Prado, Soizic,Lecellier, Gael,Thomas, Olivier P.,Raharivelomanana, Phila. (2012) 'Nukuhivensiums, indolo[2,3-a]quinoliziniums from the Marquesan plant Rauvolfia nukuhivensis'. Molecules, 17 :12015-12022 [Details]
(2012) 'Determination of the absolute configuration and evaluation of the in vitro antitumor activity of dilospirane B'
Genta-Jouve, Gregory,Ioannou, Efstathia,Mathieu, Veronique,Bruyere, Celine,Lefranc, Florence,Thomas, Olivier P.,Kiss, Robert,Roussis, Vassilios. (2012) 'Determination of the absolute configuration and evaluation of the in vitro antitumor activity of dilospirane B'. Phytochemistry Letters, 5 (4):747-751 [Details]
(2012) 'Antiparasitic bromotyrosine derivatives from the Caribbean marine sponge Aiolochroia crassa'
Galeano, Elkin,Martinez, Alejandro,Thomas, Olivier P.,Robledo, Sara,Munoz, Diana. (2012) 'Antiparasitic bromotyrosine derivatives from the Caribbean marine sponge Aiolochroia crassa'. Quimica Nova, 35 (6):1189-1193 [Details]
(2012) 'Comparative bioaccumulation kinetics of trace elements in Mediterranean marine sponges'
Genta-Jouve, Gregory,Cachet, Nadja,Oberhansli, Francois,Noyer, Charlotte,Teyssie, Jean-Louis,Thomas, Olivier P.,Lacoue-Labarthe, Thomas. (2012) 'Comparative bioaccumulation kinetics of trace elements in Mediterranean marine sponges'. Chemosphere, 89 (3):340-349 [Details]
(2012) 'Additional bioactive guanidine alkaloids from the Mediterranean sponge Crambe crambe'
Bondu, Stephanie,Genta-Jouve, Gregory,Leiros, Marta,Vale, Carmen,Guigonis, Jean-Marie,Botana, Luis M.,Thomas, Olivier P. (2012) 'Additional bioactive guanidine alkaloids from the Mediterranean sponge Crambe crambe'. RSC Advances, 2 (7):2828-2835 [Details]
(2012) 'Phytochemical analysis and antioxidant capacity of BM-21, a bioactive extract rich in polyphenolic metabolites from the sea grass Thalassia testudinum'
Regalado, Erik L.,Menendez, Roberto,Valdes, Olga,Morales, Ruth A.,Laguna, Abilio,Thomas, Olivier P.,Hernandez, Yasnay,Nogueiras, Clara,Kijjoa, Anake. (2012) 'Phytochemical analysis and antioxidant capacity of BM-21, a bioactive extract rich in polyphenolic metabolites from the sea grass Thalassia testudinum'. Natural Product Communications, 7 (1):47-50 [Details]
(2012) 'Sponge chemical diversity: from biosynthetic pathways to ecological roles'
Genta-Jouve, Gregory,Thomas, Olivier P. (2012) 'Sponge chemical diversity: from biosynthetic pathways to ecological roles'. Advances in marine biology, 62 :183-230 [Details]
(2011) 'Biochemical trade-offs: evidence for ecologically linked secondary metabolism of the sponge Oscarella balibaloi'
Ivanisevic, Julijana,Thomas, Olivier P.,Pedel, Laura,Penez, Nicolas,Ereskovsky, Alexander V.,Culioli, Gerald,Perez, Thierry. (2011) 'Biochemical trade-offs: evidence for ecologically linked secondary metabolism of the sponge Oscarella balibaloi'. PLoS One, 6 (11) [Details]
(2011) 'Acanthifoliosides, minor steroidal saponins from the Caribbean sponge Pandaros acanthifolium'
Regalado, Erik L.,Jimenez-Romero, Carlos,Genta-Jouve, Gregory,Tasdemir, Deniz,Amade, Philippe,Nogueiras, Clara,Thomas, Olivier P. (2011) 'Acanthifoliosides, minor steroidal saponins from the Caribbean sponge Pandaros acanthifolium'. Tetrahedron, 67 (5):1011-1018 [Details]
(2011) 'Antiparasitic bromotyrosine derivatives from the marine sponge Verongula rigida'
Galeano, Elkin,Thomas, Olivier P.,Robledo, Sara,Munoz, Diana,Martinez, Alejandro. (2011) 'Antiparasitic bromotyrosine derivatives from the marine sponge Verongula rigida'. Marine Drugs, 9 :1902-1913 [Details]
(2011) 'Photoprotecting action and phytochemical analysis of a multiple radical scavenger lipophilic fraction obtained from the leaf of the seagrass Thalassia testudinum'
Regalado, Erik L.,Rodriguez, Maria,Menendez, Roberto,Fernandez, Xavier,Hernandez, Ivones,Morales, Ruth A.,Fernandez, Miguel D.,Thomas, Olivier P.,Pino, Jorge A.,Concepcion, Angel R.,Laguna, Abilio. (2011) 'Photoprotecting action and phytochemical analysis of a multiple radical scavenger lipophilic fraction obtained from the leaf of the seagrass Thalassia testudinum'. Photochemistry and Photobiology, 87 (5):1058-1066 [Details]
(2011) 'New Insight into Marine Alkaloid Metabolic Pathways: Revisiting Oroidin Biosynthesis [Erratum to document cited in CA155:609335]'
Genta-Jouve, Gregory,Cachet, Nadja,Holderith, Serge,Oberhaensli, Francois,Teyssie, Jean-Louis,Jeffree, Ross,Al Mourabit, Ali,Thomas, Olivier P. (2011) 'New Insight into Marine Alkaloid Metabolic Pathways: Revisiting Oroidin Biosynthesis [Erratum to document cited in CA155:609335]'. ChemBioChem, 12 (15) [Details]
(2011) 'Antifouling Properties of Simple Indole and Purine Alkaloids from the Mediterranean Gorgonian Paramuricea clavata'
Penez, Nicolas,Culioli, Gerald,Perez, Thierry,Briand, Jean-Francois,Thomas, Olivier P.,Blache, Yves. (2011) 'Antifouling Properties of Simple Indole and Purine Alkaloids from the Mediterranean Gorgonian Paramuricea clavata'. Journal of Natural Products, 74 (10):2304-2308 [Details]
(2011) 'Cytotoxic and hemolytic steroidal glycosides from the Caribbean sponge Pandaros acanthifolium'
Regalado, Erik L.,Turk, Tom,Tasdemir, Deniz,Gorjanc, Manca,Kaiser, Marcel,Thomas, Olivier P.,Fernandez, Rogelio,Amade, Philippe. (2011) 'Cytotoxic and hemolytic steroidal glycosides from the Caribbean sponge Pandaros acanthifolium'. Steroids, 76 (12):1389-1396 [Details]
(2011) 'New Insight into Marine Alkaloid Metabolic Pathways: Revisiting Oroidin Biosynthesis'
Genta-Jouve, Gregory,Cachet, Nadja,Holderith, Serge,Oberhaensli, Francois,Teyssie, Jean-Louis,Jeffree, Ross,Al Mourabit, Ali,Thomas, Olivier P. (2011) 'New Insight into Marine Alkaloid Metabolic Pathways: Revisiting Oroidin Biosynthesis'. ChemBioChem, 12 (15):2298-2301 [Details]
(2011) 'Structure elucidation of the new citharoxazole from the Mediterranean deep-sea sponge Latrunculia (Biannulata) citharistae'
Genta-Jouve, Gregory,Francezon, Nellie,Puissant, Alexandre,Auberger, Patrick,Vacelet, Jean,Perez, Thierry,Fontana, Angelo,Mourabit, Ali Al,Thomas, Olivier P. (2011) 'Structure elucidation of the new citharoxazole from the Mediterranean deep-sea sponge Latrunculia (Biannulata) citharistae'. Magnetic Resonance in Chemistry, 49 (8):533-536 [Details]
(2011) 'Patterns of chemical diversity in the Mediterranean sponge Spongia lamella'
Noyer, Charlotte,Thomas, Olivier P.,Becerro, Mikel A. (2011) 'Patterns of chemical diversity in the Mediterranean sponge Spongia lamella'. PLoS One, 6 (6) [Details]
(2011) 'Metabolic fingerprinting as an indicator of biodiversity: towards understanding inter-specific relationships among Homoscleromorpha sponges'
Ivanisevic, Julijana,Thomas, Olivier P.,Lejeusne, Christophe,Chevaldonne, Pierre,Perez, Thierry. (2011) 'Metabolic fingerprinting as an indicator of biodiversity: towards understanding inter-specific relationships among Homoscleromorpha sponges'. Metabolomics, 7 (2):289-304 [Details]
(2011) 'Lysophospholipids in the Mediterranean Sponge Oscarella tuberculata: Seasonal Variability and Putative Biological Role'
Ivanisevic, Julijana,Perez, Thierry,Ereskovsky, Alexander V.,Barnathan, Gilles,Thomas, Olivier P. (2011) 'Lysophospholipids in the Mediterranean Sponge Oscarella tuberculata: Seasonal Variability and Putative Biological Role'. Journal of Chemical Ecology, 37 (5):537-545 [Details]
(2011) 'Bromopyrrole alkaloids from the Caribbean sponge Agelas cerebrum'
Regalado, Erik L.,Laguna, Abilio,Mendiola, Judith,Thomas, Olivier P.,Nogueiras, Clara. (2011) 'Bromopyrrole alkaloids from the Caribbean sponge Agelas cerebrum'. Quimica Nova, 34 (2):289-291 [Details]
(2011) 'Antinociception produced by Thalassia testudinum extract BM-21 is mediated by the inhibition of acid-sensing ionic channels by the phenolic compound thalassiolin B'
Garateix, Anoland,Salceda, Emilio,Menendez, Roberto,Regalado, Erik L.,Lopez, Omar,Garcia, Teidy,Morales, Ruth A.,Laguna, Abilio,Thomas, Olivier P.,Soto, Enrique. (2011) 'Antinociception produced by Thalassia testudinum extract BM-21 is mediated by the inhibition of acid-sensing ionic channels by the phenolic compound thalassiolin B'. Molecular Pain, 7 [Details]
(2011) 'Dictyotadimer A, a new dissymmetric bis-diterpene from a brown alga of the genus Dictyota'
Viano, Yannick,Bonhomme, Dominique,Ortalo-Magne, Annick,Thomas, Olivier P.,El Hattab, Mohamed,Piovetti, Louis,Blache, Yves,Culioli, Gerald. (2011) 'Dictyotadimer A, a new dissymmetric bis-diterpene from a brown alga of the genus Dictyota'. Tetrahedron Letters, 52 (9):1031-1035 [Details]
(2011) 'Furfuran lignans and a flavone from Artemisia gorgonum Webb and their in vitro activity against Plasmodium falciparum'
Ortet, Risoleta,Prado, Soizic,Regalado, Erik L.,Valeriote, Frederick A.,Media, Joseph,Mendiola, Judith,Thomas, Olivier P. (2011) 'Furfuran lignans and a flavone from Artemisia gorgonum Webb and their in vitro activity against Plasmodium falciparum'. Journal of Ethnopharmacology, 138 (2):637-640 [Details]
(2010) 'Polar alkaloids from the Caribbean marine sponge Niphates digitalis'
Regalado, Erik L.,Mendiola, Judith,Laguna, Abilio,Nogueiras, Clara,Thomas, Olivier P. (2010) 'Polar alkaloids from the Caribbean marine sponge Niphates digitalis'. Natural Product Communications, 5 (8):1187-1190 [Details]
(2010) 'Composition and Biological Properties of the Volatile Oil of Artemisia gorgonum Webb'
Ortet, Risoleta,Thomas, Olivier P.,Regalado, Erik L.,Pino, Jorge A.,Filippi, Jean-Jacques,Fernandez, Miguel D. (2010) 'Composition and Biological Properties of the Volatile Oil of Artemisia gorgonum Webb'. Chemistry & Biodiversity, 7 (5):1325-1332 [Details]
(2010) 'Antiprotozoal Steroidal Saponins from the Marine Sponge Pandaros acanthifolium'
Regalado, Erik L.,Tasdemir, Deniz,Kaiser, Marcel,Cachet, Nadja,Amade, Philippe,Thomas, Olivier P. (2010) 'Antiprotozoal Steroidal Saponins from the Marine Sponge Pandaros acanthifolium'. Journal of Natural Products, 73 (8):1404-1410 [Details]
(2009) 'Njaoaminiums A, B, and C: cyclic 3-alkylpyridinium salts from the marine sponge Reniera sp'
Laville, Remi,Genta-Jouve, Gregory,Urda, Carlos,Fernandez, Rogelio,Thomas, Olivier P.,Reyes, Fernando,Amade, Philippe. (2009) 'Njaoaminiums A, B, and C: cyclic 3-alkylpyridinium salts from the marine sponge Reniera sp'. Molecules, 14 (11):4716-4724 [Details]
(2009) 'Composition and antioxidant properties of the essential oil of the endemic cape verdean Satureja forbesii'
Ortet, Risoleta,Regalado, Erik L.,Thomas, Olivier P.,Pino, Jorge A.,Fernandez, Miguel D.,Filippi, Jean-Jacques. (2009) 'Composition and antioxidant properties of the essential oil of the endemic cape verdean Satureja forbesii'. Natural Product Communications, 4 (9):1277-1280 [Details]
(2009) 'Bioactive Guanidine Alkaloids from two Caribbean Marine Sponges'
Laville, Remi,Thomas, Olivier P.,Berrue, Fabrice,Marquez, Diana,Vacelet, Jean,Amade, Philippe. (2009) 'Bioactive Guanidine Alkaloids from two Caribbean Marine Sponges'. Journal of Natural Products, 72 (9):1589-1594 [Details]
(2009) 'Parazoanthines A-E, Hydantoin Alkaloids from the Mediterranean Sea Anemone Parazoanthus axinellae'
Cachet, Nadja,Genta-Jouve, Gregory,Regalado, Erik L.,Mokrini, Redouane,Amade, Philippe,Culioli, Gerald,Thomas, Olivier P. (2009) 'Parazoanthines A-E, Hydantoin Alkaloids from the Mediterranean Sea Anemone Parazoanthus axinellae'. Journal of Natural Products, 72 (9):1612-1615 [Details]
(2009) 'Steroidal glycosides from the marine sponge Pandaros acanthifolium'
Cachet, Nadja,Regalado, Erik L.,Genta-Jouve, Gregory,Mehiri, Mohamed,Amade, Philippe,Thomas, Olivier P. (2009) 'Steroidal glycosides from the marine sponge Pandaros acanthifolium'. Steroids, 74 (9):746-750 [Details]
(2009) '3-Alkylpyridinium salts from Haplosclerida marine sponges: isolation, structure elucidations, and biosynthetic considerations'
Laville, Remi,Amade, Philippe,Thomas, Olivier P. (2009) '3-Alkylpyridinium salts from Haplosclerida marine sponges: isolation, structure elucidations, and biosynthetic considerations'. Pure and Applied Chemistry, 81 (6):1033-1040 [Details]

Book Chapters

  Year Publication
(2020) 'Dictyotaceae (Dictyotales, Phaeophyceae) species from French Polynesia: current knowledge and future research'
Theophilus, Tohei Vieira, Christophe Culioli, Gérald Thomas, Olivier P. N'Yeurt, Antoine De Ramon Andréfouët, Serge Mattio, Lydiane Payri, Claude E. Zubia, Mayalen (2020) 'Dictyotaceae (Dictyotales, Phaeophyceae) species from French Polynesia: current knowledge and future research' In: Advances in Botanical Research. Amsterdam, Netherlands: Elsevier. [Details]
(2017) 'Current Status and Perspectives in Marine Biodiscovery'
Firsova D., Mahajan N., Solanki H., Morrow C., Thomas O.P. (2017) 'Current Status and Perspectives in Marine Biodiscovery' In: Bioprospecting. Topics in Biodiversity and Conservation. Vol 16. Cham: Springer. [Details]
(2016) 'Metabolomic Contributions to Chemical Ecology'
Philippe Potin , Florence Nicolè, Olivier P. Thomas (2016) 'Metabolomic Contributions to Chemical Ecology' In: Chemical Ecology. :137-158 Hoboken, NJ, USA: John Wiley & Sons, Inc.. [DOI] [Details]
(2014) 'Toxins from marine invertebrates'
Ternon, Eva,Thomas, Olivier P. (2014) 'Toxins from marine invertebrates' In: Seafood Freshwater Toxins (3rd Ed.). :77-103 Boca Raton, FL: CRC Press. [Details]
(2011) 'Polyketide assembly mimics and biomimetic access to aromatic rings'
Genta-Jouve, Gregory,Antoniotti, Sylvain,Thomas, Olivier P. (2011) 'Polyketide assembly mimics and biomimetic access to aromatic rings' In: Biomimetic Organic Synthesis. :471-502 Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA. [Details]

Languages

  Language
Spanish
French
English

Reviews

  Journal Role
Journal Of Natural Products Reviewer
Polar Biology Reviewer
Scientific Reports Editoral Board
Tetrahedron Reviewer
Frontiers In Ecology And The Environment Editoral Board
Phytochemistry Reviewer
Planta Medica Reviewer
Organic Letters Reviewer
Plos One Reviewer
Journal of chemical ecology Reviewer

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
4th Year BSC and BPC Bioorganic Chemistry CH4108 and 4104 Structure Elucidation by NMR
3rd year Chemistry Nuclear Magnetic Resonance CH326
3rd year Chemistry Experimental Chemistry CH333 Nuclear Magnetic Resonance
3rd Year BSc Natural Products and Drugs CH332 Metabolic Pathways
2nd Year BSc Separation science and water chemistry CH205
2nd Year BSc Organic Chemistry CH202 Practicals

Internal Collaborators

  Name Description of Collaboration
Louise Allcock
SFI Grant
Grace McCormack
Common interest in the the application of metabolomic approaches to understand the systematics of Haliclona sponges
Abhay PANDIT
CURAM-Biomaterials and medical devices

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
Alan DOBSON UCC IRELAND
Marine microbes and metagenomics
Gregory Genta-Jouve University Paris Descartes FRANCE
Determination of the stereochemistry of natural products and environmental metabolomics
Erwan Poupon Universite Paris Sud FRANCE
Study of sponge metabolic pathways
Thierry Perez IMBE Marseille FRANCE
Multidiscilpinary approach in sponge ecology and chemical ecology
Luis Botana Universidad de Santiago de Compostella SPAIN
Biological applications of our marine natural compounds
Fernando REYES Fundacion Medina SPAIN
antimicrobial bioassays
Mayalen Zubia University French Polynesia FRANCE
Chemical ecology of cyanobacteria from the Pacific
Claude Payri UMR Entropie, IRD New Caledonia FRANCE
Chemical ecology of Pacific macroalgae