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Chemistry

Prof Olivier Thomas

PhD

 
researcher
 

Biography

2015-: Established Professor in Marine Biodiscovery at NUI Galway
2012: Professor in Marine Natural Product Chemistry at University Nice Sophia Antipolis, France
2004: Lecturer in Marine Natural Product Chemistry at University Nice Sophia Antipolis, France
2002: Post-Doctorate at CEA Saclay, France
2002: PhD in Organic Chemistry at University Paris Descartes, France
under the supervision of Henri-Philippe HUSSON
1999: Master Degree in Organic Chemistry from University Paris Descartes, France
1996-1998: Teacher at French School La Condamine Quito, Ecuador
1996: Agregation in Chemistry at Ecole Normale Superieure de Cachan, France

Research Interests

Our research focuses on the specialized metabolites, also called natural products, produced by marine organisms and especially marine invertebrates like sponges, zoantharians, soft corals but also algae, microalgae, or cyanobacteria. While our main playground for biodiscovery is the North-eastern Atlantic and especially the Irish waters from the seashore until the deep sea, through collaborations with local marine biologists and ecologists, we work in the Caribbean and Mediterranean Seas or the Atlantic and Pacific Oceans.
We have expertise in the purification by HPLC and structure elucidation by NMR and MS of all types of specialized metabolites. Such natural products may find applications in the pharmaceutical, the cosmetical or agri-food sectors. Through the establishment of a National Marine Biodiscovery Laboratory in Ireland we strive for a strong collaboration between marine biologists, taxonomists, microbiologists, and chemists to organize a biological and chemical repository of marine products. We are also engaged in several projects in marine chemical ecology first to understand their metabolic pathways but also their ecological role in the environment. Although omnipresent, the chemical mediation in the marine environment is still very poorly understood. We develop new tools to point out the key role of some chemical cues in the structure of ecosystems. These findings may also find applications in several sectors like the aquaculture sector. These approaches are of special interest in the field of marine biotoxins. Under the impacts of anthropogenic activities and global changes the proliferation of non-indigenous species and especially toxic dinoflagellates and cyanobacteria affect local ecosystems through the production and release of specialized metabolites. The marine seafood sector is frequently under the threat of such toxic contamination. To address these basic and applied questions we want to apply the recent technological and more global approach called marine environmental metabolomics by mass spectrometry but also nuclear magnetic resonance.

Keywords:  Natural Product Chemistry, Bioactive Natural Products, Chemical Ecology, Marine Invertebrates, Sponges, Microalgae, Metabolic Pathways, Metabolomics

Research Projects

  Project Start Date End Date
CULLEN FELLOWSHIP - CULTURE OPTIMISATION, AND BIOACTIVITY OF SELECTED TOXIC IRISH MICROALGAE 01-OCT-18 30-SEP-21
MARINE CHIROPTICS 01-DEC-17 30-NOV-18
ALERTOX-NET (Interreg) 01-OCT-17 30-SEP-20
Registrars Office 01-NOV-15 31-OCT-20
OCEAN-15 04-JAN-16 31-DEC-19
TARA-PACIFIC 01-JUL-16 01-JUL-18

Contract Researchers

  Researcher Name Project Role Funding Body
Kevin CALABRO NMBLI Post-Doctorate in the Structure Elucidation of Marine Toxins
Eva TERNON French ANR OCEAN-15 Post-Doctorate in Plankton Chemical Ecology
Christine MORROW Integrative Taxonomy Marine Sponges Post-Doctorate in cosupervision with Grace McCormack NUIG
Sathees KUMAR Biology and Chemistry of Irish Marine Ascidians Post-Doctorate in cosupervision with Grace McCormack NUIG
Maria MIGUEL Sponges from the Tara Expedition PhD Hardiman
Sam AFOULLOUSS Deep Sea Marine Biodiscovery (Louise Allcock) PhD student cosupervised with Louise Allcock
Karla JARAMILLO Marine Biodiversity in Ecuador PhD student in codirection with Grace McCormack NUIG and Jenny Rodriguez CENAIM Ecuador
Hiren SOLANKI Marine Biodiscovery PhD Student in cosupervision with Christine MORROW (NUIG) and Mayalen ZUBIA (French Polynesia University)
Paul GUILLEN Natural Product Chemistry of Ecuadorian Cnidarians PhD student between NUI Galway and CENAIM Ecuador
Julie GAUBERT Brown Algae Chemical Ecology PhD Student in codirection with Claude PAYRI at Noumea New Caledonia
Elliot MURPHY NMBLI MSc in Natural Product Chemistry of Marine Macroalgae
Manon PERALEZ OCEAN-15 Research Assitant in Natural Product Chemistry of Dinoflagellates
Perrine LASSERRE NMBLI Research Assistant in Bioassays and Marine Toxins
Navdeep KAUR NMBLI Research Assistant in Marine Natural Product Chemistry
Daniel RODRIGUES NMBLI Research Assistant in Marine Biology

Peer Reviewed Journals

  Year Publication
(2019) 'Metabolomic variability of four macroalgal species of the genus Lobophora using diverse approaches'
Gaubert, Julie,Greff, Stephane,Thomas, Olivier P.,Payri, Claude E. (2019) 'Metabolomic variability of four macroalgal species of the genus Lobophora using diverse approaches'. Phytochemistry, 162 :165-172 [Details]
(2019) 'Structure Revision of Microginins 674 and 690 from the Cultured Cyanobacterium Microcystis aeruginosa'
Calabro, Kevin,Genta-Jouve, Gregory,Thomas, Olivier P. (2019) 'Structure Revision of Microginins 674 and 690 from the Cultured Cyanobacterium Microcystis aeruginosa'. Journal of Natural Products, [Details]
(2019) 'Insights into the Biosynthesis of Cyclic Guanidine Alkaloids from Crambeidae Marine Sponges'
Silva, Siguara B. L.,Oberhaensli, Francois,Tribalat, Marie-Aude,Genta-Jouve, Gregory,Teyssie, Jean-Louis,Dechraoui-Bottein, Marie-Yasmine,Gallard, Jean-Francois,Evanno, Laurent,Poupon, Erwan,Thomas, Olivier P. (2019) 'Insights into the Biosynthesis of Cyclic Guanidine Alkaloids from Crambeidae Marine Sponges'. Angewandte Chemie-International Edition In English, 58 (2):520-525 [Details]
(2019) 'Treasures from the Deep: Characellides as Anti-Inflammatory Lipoglycotripeptides from the Sponge Characella pachastrelloides'
Afoullouss, Sam,Calabro, Kevin,Genta-Jouve, Gregory,Gegunde, Sandra,Alfonso, Amparo,Nesbitt, Robert,Morrow, Christine,Alonso, Eva,Botana, Luis,Allcock, Louise,Thomas, Olivier P. (2019) 'Treasures from the Deep: Characellides as Anti-Inflammatory Lipoglycotripeptides from the Sponge Characella pachastrelloides'. Organic Letters, 21 (1):246-251 [Details]
(2018) 'Stereochemical Study of Puna'auic Acid, an Allenic Fatty Acid from the Eastern Indo-Pacific Cyanobacterium Pseudanabaena sp'
Roulland, Emmanuel,Solanki, Hiren,Calabro, Kevin,Zubia, Mayalen,Genta-Jouve, Gregory,Thomas, Olivier P. (2018) 'Stereochemical Study of Puna'auic Acid, an Allenic Fatty Acid from the Eastern Indo-Pacific Cyanobacterium Pseudanabaena sp'. Organic Letters, 20 (8):2311-2314 [Details]
(2018) 'Suberitane sesterterpenoids from the Antarctic sponge Phorbas areolatus (Thiele, 1905)'
Solanki, Hiren,Angulo-Preckler, Carlos,Calabro, Kevin,Kaur, Navdeep,Lasserre, Perrine,Cautain, Bastien,de la Cruz, Mercedes,Reyes, Fernando,Avila, Conxita,Thomas, Olivier P. (2018) 'Suberitane sesterterpenoids from the Antarctic sponge Phorbas areolatus (Thiele, 1905)'. Tetrahedron Letters, 59 (36):3353-3356 [Details]
(2018) 'Ecdysonelactones, ecdysteroids from the tropical eastern pacific zoantharian Antipathozoanthus hickmani'
Guillen, Paul O.,Calabro, Kevin,Jaramillo, Karla B.,Dominguez, Cristobal,Genta-Jouve, Gregory,Rodriguez, Jenny,Thomas, Olivier P. (2018) 'Ecdysonelactones, ecdysteroids from the tropical eastern pacific zoantharian Antipathozoanthus hickmani'. Marine Drugs, 16 (2) [Details]
(2018) 'Distance interaction between marine cave-dwelling sponges and crustaceans'
Santonja, Mathieu,Greff, Stephane,Le Croller, Marie,Thomas, Olivier P.,Perez, Thierry. (2018) 'Distance interaction between marine cave-dwelling sponges and crustaceans'. Marine Biology (Heidelberg, Germany), 165 (7):1-15 [Details]
(2018) 'Marine invasive macroalgae: Turning a real threat into a major opportunity - the biotechnological potential of Sargassum muticum and Asparagopsis armata'
Pinteus, Susete,Lemos, Marco F.L.,Alves, Celso,Neugebauer, Agnieszka,Silva, Joana,Thomas, Olivier P.,Botana, Luis M.,Gaspar, Helena,Pedrosa, Rui (2018) 'Marine invasive macroalgae: Turning a real threat into a major opportunity - the biotechnological potential of Sargassum muticum and Asparagopsis armata'. Algal Research, 34 :217-234 [Details]
(2018) 'Zoanthamine alkaloids from the zoantharian Zoanthus cf. pulchellus and their effects in neuroinflammation'
Guillen, Paul O.,Gegunde, Sandra,Jaramillo, Karla B.,Alfonso, Amparo,Calabro, Kevin,Alonso, Eva,Rodriguez, Jenny,Botana, Luis M.,Thomas, Olivier P. (2018) 'Zoanthamine alkaloids from the zoantharian Zoanthus cf. pulchellus and their effects in neuroinflammation'. Marine Drugs, 16 (7) [Details]
(2018) 'Variations in Microbial Diversity and Metabolite Profiles of the Tropical Marine Sponge Xestospongia muta with Season and Depth'
Villegas-Plazas, Marcela,Wos-Oxley, Melissa L.,Sanchez, Juan A.,Pieper, Dietmar H.,Thomas, Olivier P.,Junca, Howard. (2018) 'Variations in Microbial Diversity and Metabolite Profiles of the Tropical Marine Sponge Xestospongia muta with Season and Depth'. Microbial Ecology, [Details]
(2018) 'Unusual polycyclic fused product by oxidative enzymatic dimerisation of 5-methylpyrogallol catalyzed by horseradish peroxidase/H2O2'
Bouges, Helene,Calabro, Kevin,Thomas, Olivier P.,Antoniotti, Sylvain. (2018) 'Unusual polycyclic fused product by oxidative enzymatic dimerisation of 5-methylpyrogallol catalyzed by horseradish peroxidase/H2O2'. Molecules, 23 (10) [Details]
(2018) 'Callyspongidic Acids: Amphiphilic Diacids from the Tropical Eastern Pacific Sponge Callyspongia cf. californica'
Calabro, Kevin,Chalen, Bolivar E.,Genta-Jouve, Gregory,Jaramillo, Karla B.,Dominguez, Cristobal,de la Cruz, Mercedes,Cautain, Bastien,Reyes, Fernando,Thomas, Olivier P.,Rodriguez, Jenny. (2018) 'Callyspongidic Acids: Amphiphilic Diacids from the Tropical Eastern Pacific Sponge Callyspongia cf. californica'. Journal of Natural Products, 81 (10):2301-2305 [Details]
(2018) 'Metabolome variability for two Mediterranean sponge species of the genus Haliclona: specificity, time, and space'
Reverter, Miriam,Tribalat, Marie-Aude,Perez, Thierry,Thomas, Olivier P. (2018) 'Metabolome variability for two Mediterranean sponge species of the genus Haliclona: specificity, time, and space'. Metabolomics, 14 (9):1-12 [Details]
(2018) 'Allelopathic interactions between the benthic toxic dinoflagellate Ostreopsis cf. ovata and a co-occurring diatom'
Ternon, Eva,Pavaux, Anne-Sophie,Marro, Sophie,Thomas, Olivier P.,Lemee, Rodolphe (2018) 'Allelopathic interactions between the benthic toxic dinoflagellate Ostreopsis cf. ovata and a co-occurring diatom'. Harmful Algae, 75 :35-44 [Details]
(2018) 'Marine sponges as a powerful tool for trace elements biomonitoring studies in coastal environment'
Orani, Anna Maria,Barats, Aurelie,Vassileva, Emilia,Thomas, Olivier P. (2018) 'Marine sponges as a powerful tool for trace elements biomonitoring studies in coastal environment'. Marine Pollution Bulletin, 131 :633-645 [Details]
(2018) 'Comparative study on the bioaccumulation and biotransformation of arsenic by some northeastern Atlantic and northwestern Mediterranean sponges'
Orani, Anna Maria,Barats, Aurelie,Zitte, Wendy,Morrow, Christine,Thomas, Olivier P. (2018) 'Comparative study on the bioaccumulation and biotransformation of arsenic by some northeastern Atlantic and northwestern Mediterranean sponges'. Chemosphere, 201 :826-839 [Details]
(2018) 'Assessing the Zoantharian Diversity of the Tropical Eastern Pacific through an Integrative Approach'
Jaramillo, Karla B.,Reverter, Miriam,Guillen, Paul O.,McCormack, Grace,Rodriguez, Jenny,Sinniger, Frederic,Thomas, Olivier P. (2018) 'Assessing the Zoantharian Diversity of the Tropical Eastern Pacific through an Integrative Approach'. Scientific Reports, 8 (1) [Details]
(2017) 'Poecillastrosides, steroidal saponins from the mediterranean deep-sea sponge Poecillastra compressa (Bowerbank, 1866)'
Calabro, Kevin,Kalahroodi, Elaheh Lotfi,Rodrigues, Daniel,Diaz, Caridad,Cruz, Mercedes de la,Cautain, Bastien,Laville, Remi,Reyes, Fernando,Perez, Thierry,Soussi, Bassam,Thomas, Olivier P. (2017) 'Poecillastrosides, steroidal saponins from the mediterranean deep-sea sponge Poecillastra compressa (Bowerbank, 1866)'. Marine Drugs, 15 (7):1-12 [Details]
(2017) 'How environmental factors affect the production of guanidine alkaloids by the mediterranean sponge Crambe crambe'
Ternon, Eva,Perino, Erica,Manconi, Renata,Pronzato, Roberto,Thomas, Olivier P. (2017) 'How environmental factors affect the production of guanidine alkaloids by the mediterranean sponge Crambe crambe'. Marine Drugs, 15 (6) [Details]
(2017) 'Introducing the 2016 CASMI contest'
Genta-Jouve, Gregory, Thomas, Olivier P., Schymanski, Emma L.,Neumann, Steffen (2017) 'Introducing the 2016 CASMI contest'. Phytochemistry Letters, 21 (Supplement C) [Details]
(2017) 'The Marine Guanidine Alkaloid Crambescidin 816 Induces Calcium Influx and Cytotoxicity in Primary Cultures of Cortical Neurons through Glutamate Receptors'
Mendez, Aida G.,Juncal, Andrea Boente,Silva, Siguara B. L.,Thomas, Olivier P.,Martin Vazquez, Victor,Alfonso, Amparo,Vieytes, Mercedes R.,Vale, Carmen,Botana, Luis M. (2017) 'The Marine Guanidine Alkaloid Crambescidin 816 Induces Calcium Influx and Cytotoxicity in Primary Cultures of Cortical Neurons through Glutamate Receptors'. ACS Chemical Neuroscience, 8 (7):1609-1617 [Details]
(2017) 'Evaluation of the Protective Effects of Sarains on H2O2-Induced Mitochondrial Dysfunction and Oxidative Stress in SH-SY5Y Neuroblastoma Cells'
Alvarino, Rebeca,Alonso, Eva,Tribalat, Marie-Aude,Gegunde, Sandra,Thomas, Olivier P.,Botana, Luis M. (2017) 'Evaluation of the Protective Effects of Sarains on H2O2-Induced Mitochondrial Dysfunction and Oxidative Stress in SH-SY5Y Neuroblastoma Cells'. Neurotoxicity Research, 32 (3):368-380 [Details]
(2017) 'Isoguanosine derivatives from the Northeastern Atlantic sponge Clathria (Microciona) strepsitoxa'
Firsova, Daria,Calabro, Kevin,Lasserre, Perrine,Reyes, Fernando,Thomas, Olivier P. (2017) 'Isoguanosine derivatives from the Northeastern Atlantic sponge Clathria (Microciona) strepsitoxa'. Tetrahedron Letters, 58 (49):4652-4654 [Details]
(2017) 'N-Didehydrotyrosine identified from the Northeastern Atlantic marine sponge Hymeniacidon perlevis after Chemical Screening'
Nipun Mahajan, Kevin Calabro, Christine Morrow, Olivier P Thomas (2017) 'N-Didehydrotyrosine identified from the Northeastern Atlantic marine sponge Hymeniacidon perlevis after Chemical Screening'. Natural Product Communications, 12 [Details]
(2017) 'Poecillastrosides, Steroidal Saponins from the Mediterranean Deep-Sea Sponge Poecillastra compressa (Bowerbank, 1866)'
Calabro, K.; Kalahroodi, E.L.; Rodrigues, D.; Díaz, C.; Cruz, M.; Cautain, B.; Laville, R.; Reyes, F.; Pérez, T.; Soussi, B.; Thomas, O.P. (2017) 'Poecillastrosides, Steroidal Saponins from the Mediterranean Deep-Sea Sponge Poecillastra compressa (Bowerbank, 1866)'. Marine Drugs, 15 [DOI] [Details]
(2017) 'Bio-invasive ascidians in Ireland: A threat for the shellfish industry but also a source of high added value products'
Satheesh Kumar Palanisamy, Olivier P. Thomas & Grace P. McCormack (2017) 'Bio-invasive ascidians in Ireland: A threat for the shellfish industry but also a source of high added value products'. Bioengineered, [DOI] [Details]
(2017) 'Terrazoanthines, 2-Aminoimidazole Alkaloids from the Tropical Eastern Pacific Zoantharian Terrazoanthus onoi'
Guillen, Paul O.,Jaramillo, Karla B.,Genta-Jouve, Gregory,Sinniger, Frederic,Rodriguez, Jenny,Thomas, Olivier P. (2017) 'Terrazoanthines, 2-Aminoimidazole Alkaloids from the Tropical Eastern Pacific Zoantharian Terrazoanthus onoi'. Organic Letters, [Details]
(2017) 'Discrimination of Four Marine Biofilm-Forming Bacteria by LC-MS Metabolomics and Influence of Culture Parameters'
Favre, Laurie,Ortalo-Magne, Annick,Greff, Stephane,Perez, Thierry,Thomas, Olivier Paul,Martin, Jean-Charles,Culioli, Gerald. (2017) 'Discrimination of Four Marine Biofilm-Forming Bacteria by LC-MS Metabolomics and Influence of Culture Parameters'. Journal of Proteome Research, [Details]
(2017) 'Isolation and synthesis of pygmanilines, phenylurea derivatives from the Northeastern Atlantic lichen Lichina pygmaea'
Mahajan, Nipun,Chadda, Rekha,Calabro, Kevin,Solanki, Hiren,O'Connell, Enda,Murphy, Paul V.,Thomas, Olivier P. (2017) 'Isolation and synthesis of pygmanilines, phenylurea derivatives from the Northeastern Atlantic lichen Lichina pygmaea'. Tetrahedron Letters, 58 (12):1237-1239 [Details]
(2017) 'The interaction between the proliferating macroalga Asparagopsis taxiformis and the coral Astroides calycularis induces changes in microbiome and metabolomic fingerprints'
Greff, Stephane,Aires, Tania,Serrao, Ester A.,Engelen, Aschwin H.,Thomas, Olivier P.,Perez, Thierry. (2017) 'The interaction between the proliferating macroalga Asparagopsis taxiformis and the coral Astroides calycularis induces changes in microbiome and metabolomic fingerprints'. Scientific Reports, 7 [Details]
(2017) 'Chemogeography of the red macroalgae Asparagopsis: metabolomics, bioactivity, and relation to invasiveness'
Greff, Stephane,Zubia, Mayalen,Payri, Claude,Thomas, Olivier P.,Perez, Thierry. (2017) 'Chemogeography of the red macroalgae Asparagopsis: metabolomics, bioactivity, and relation to invasiveness'. Metabolomics, 13 (4):1-13 [Details]
(2017) 'Biological activities associated to the chemodiversity of the brown algae belonging to genus Lobophora (Dictyotales, Phaeophyceae)'
Vieira, Christophe,Gaubert, Julie,De Clerck, Olivier,Payri, Claude,Culioli, Gerald,Thomas, Olivier P. (2017) 'Biological activities associated to the chemodiversity of the brown algae belonging to genus Lobophora (Dictyotales, Phaeophyceae)'. Phytochemistry Reviews, 16 :1-17 [Details]
(2017) 'Autumnalamide targeted proteins of the immunophilin family'
Sanchez, Jon Andoni,Alfonso, Amparo,Thomas, Olivier P.,Botana, Lui­s M. (2017) 'Autumnalamide targeted proteins of the immunophilin family'. Immunobiology, 222 (2):241-250 [DOI] [Details]
(2016) 'Spherulization as a process for the exudation of chemical cues by the encrusting sponge C. crambe'
Eva Ternon, Lina Zarate, Sandrine Chenesseau, Julie Croué, Rémi Dumollard, Marcelino T. Suzuki & Olivier P. Thomas (2016) 'Spherulization as a process for the exudation of chemical cues by the encrusting sponge C. crambe'. Scientific Reports, 6 [ARAN Link] [Details]
(2016) 'Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model'
María Roel, Juan A. Rubiolo, Jorge Guerra-Varela, Siguara B. L. Silva, Olivier P. Thomas, Pablo Cabezas-Sainz, Laura Sánchez, Rafael López, Luis M. Botana (2016) 'Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model'. Oncotarget, 7 (50):83071-83087 [DOI] [Details]
(2016) 'Does the Chemical Diversity of the Order Haplosclerida (Phylum Porifera: Class Demospongia) Fit with Current Taxonomic Classification?'
Tribalat, Marie-Aude,Marra, Maria V.,McCormack, Grace P.,Thomas, Olivier P. (2016) 'Does the Chemical Diversity of the Order Haplosclerida (Phylum Porifera: Class Demospongia) Fit with Current Taxonomic Classification?'. Planta Medica, 82 (9-10):843-856 [ARAN Link] [Details]
(2016) 'Metabolomics for the Authentication of Natural Extracts Used in Flavours and Fragrances: the Case Study of Violet Leaf Absolutes from Viola odorata'
Saint-Lary L;Roy C;Paris JP;Martin JF;Thomas OP;Fernandez X; (2016) 'Metabolomics for the Authentication of Natural Extracts Used in Flavours and Fragrances: the Case Study of Violet Leaf Absolutes from Viola odorata'. Chemistry & biodiversity, 13 (6):737-747 [DOI] [Details]
(2016) 'Allelopathic interactions between the brown algal genus Lobophora (Dictyotales, Phaeophyceae) and scleractinian corals'
Vieira, Christophe,Thomas, Olivier P.,Culioli, Gerald,Genta-Jouve, Gregory,Houlbreque, Fanny,Gaubert, Julie,De Clerck, Olivier,Payri, Claude E. (2016) 'Allelopathic interactions between the brown algal genus Lobophora (Dictyotales, Phaeophyceae) and scleractinian corals'. Scientific Reports, 6 [ARAN Link] [Details]
(2016) 'Metabolomics as a tool for the authentication of rose extracts used in flavour and fragrance area'
Saint-Lary, Laure,Roy, Celine,Paris, Jean-Philippe,Martin, Jean-Francois,Thomas, Olivier P.,Fernandez, Xavier. (2016) 'Metabolomics as a tool for the authentication of rose extracts used in flavour and fragrance area'. Metabolomics, 12 (3):1-11 [Details]
(2016) 'On the use of 31P NMR for the quantification of hydrosoluble phosphorus-containing compounds in coral host tissues and cultured zooxanthellae'
Godinot, Claire,Gaysinski, Marc,Thomas, Olivier P.,Ferrier-Pages, Christine,Grover, Renaud. (2016) 'On the use of 31P NMR for the quantification of hydrosoluble phosphorus-containing compounds in coral host tissues and cultured zooxanthellae'. Scientific Reports, 6 [ARAN Link] [Details]
(2016) 'Gersemiols A-“C and Eunicellol A, Diterpenoids from the Arctic Soft Coral Gersemia fruticosa'
Angulo-Preckler, Carlos,Genta-Jouve, Grégory,Mahajan, Nipun,de la Cruz, Mercedes,de Pedro, Nuria,Reyes, Fernando,Iken, Katrin,Avila, Conxita,Thomas, Olivier P. (2016) 'Gersemiols A-“C and Eunicellol A, Diterpenoids from the Arctic Soft Coral Gersemia fruticosa'. Journal Of Natural Products, 79 :1132-1139 [Details]
(2015) 'Speciation of americium in seawater and accumulation in the marine sponge Aplysina cavernicola'
Maloubier, Melody,Michel, Herve,Solari, Pier Lorenzo,Moisy, Philippe,Tribalat, Marie-Aude,Oberhaensli, Francois R.,Dechraoui Bottein, Marie Yasmine,Thomas, Olivier P.,Monfort, Marguerite,Moulin, Christophe,Den Auwer, Christophe. (2015) 'Speciation of americium in seawater and accumulation in the marine sponge Aplysina cavernicola'. Dalton Transactions, 44 (47):20584-20596 [Details]
(2015) 'Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cells'
Fiorini, Laura,Sauvard, Lucy,Cazareth, Julie,Lalli, Enzo,Mus-Veteau, Isabelle,Tribalat, Marie-Aude,Sauvard, Lucy,Thomas, Olivier P.,Broutin, Isabelle,Thomas, Olivier P. (2015) 'Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cells'. Oncotarget, 6 (26):22282-22297 [Details]
(2015) 'Extraction, Purification, and NMR Analysis of Terpenes from Brown Algae'
Gaysinski, Marc,Ortalo-Magne, Annick,Thomas, Olivier P.,Culioli, Gerald (2015) 'Extraction, Purification, and NMR Analysis of Terpenes from Brown Algae'. Methods in molecular biology (Clifton, N.J.), 1308 :207-23 [Details]
(2015) 'Crambescin C1 Exerts a Cytoprotective Effect on HepG2 Cells through Metallothionein Induction'
Roel, Maria,Rubiolo, Juan A.,Botana, Luis M.,Ternon, Eva,Thomas, Olivier P.,Thomas, Olivier P.,Vieytes, Mercedes R. (2015) 'Crambescin C1 Exerts a Cytoprotective Effect on HepG2 Cells through Metallothionein Induction'. Marine drugs, 13 (8):4633-53 [Details]
(2015) 'Indole alkaloids from the Marquesan plant Rauvolfia nukuhivensis and their effects on ion channels'
Martin, Nicolas J.,Ferreiro, Sara F.,Barbault, Florent,Nicolas, Mael,Lecellier, Gael,Paetz, Christian,Gaysinski, Marc,Alonso, Eva,Thomas, Olivier P.,Botana, Luis M.,Raharivelomanana, Phila. (2015) 'Indole alkaloids from the Marquesan plant Rauvolfia nukuhivensis and their effects on ion channels'. Phytochemistry (Elsevier), 109 :84-95 [Details]
(2015) 'Antitumor and antimicrobial potential of bromoditerpenes isolated from the red alga, Sphaerococcus coronopifolius'
Rodrigues, Daniel,Alves, Celso,Horta, Andre,Pinteus, Susete,Silva, Joana,Culioli, Gerald,Thomas, Olivier P.,Pedrosa, Rui. (2015) 'Antitumor and antimicrobial potential of bromoditerpenes isolated from the red alga, Sphaerococcus coronopifolius'. Marine Drugs, 13 (2) [Details]
(2015) 'Gambierone, a Ladder-Shaped Polyether from the Dinoflagellate Gambierdiscus belizeanus'
Rodriguez, Ines,Genta-Jouve, Gregory,Alfonso, Carmen,Calabro, Kevin,Alonso, Eva,Sanchez, Jon A.,Alfonso, Amparo,Thomas, Olivier P.,Botana, Luis M. (2015) 'Gambierone, a Ladder-Shaped Polyether from the Dinoflagellate Gambierdiscus belizeanus'. Organic Letters, 17 (10):2392-2395 [Details]
(2015) 'Cystophloroketals A-E, unusual phloroglucinol-meroterpenoid hybrids from the brown alga Cystoseira tamariscifolia'
El Hattab, Mohamed,Genta-Jouve, Gregory,Bouzidi, Naima,Ortalo-Magne, Annick,Hellio, Claire,Marechal, Jean-Philippe,Piovetti, Louis,Thomas, Olivier P.,Culioli, Gerald. (2015) 'Cystophloroketals A-E, unusual phloroglucinol-meroterpenoid hybrids from the brown alga Cystoseira tamariscifolia'. Journal of Natural Products, 78 (7):1663-1670 [Details]
(2015) 'Metabolomic profiling reveals deep chemical divergence between two morphotypes of the zoanthid Parazoanthus axinellae'
Cachet, Nadja,Genta-Jouve, Gregory,Ivanisevic, Julijana,Chevaldonne, Pierre,Sinniger, Frederic,Culioli, Gerald,Perez, Thierry,Thomas, Olivier P. (2015) 'Metabolomic profiling reveals deep chemical divergence between two morphotypes of the zoanthid Parazoanthus axinellae'. Scientific Reports, 5 [Details]
(2015) 'Eryloside W, a triterpenoid saponin from the sponge Dictyonella marsilii'
Genta-Jouve, Gregory,Boughanem, Cecile,Ocana, Oscar,Perez, Thierry,Thomas, Olivier P. (2015) 'Eryloside W, a triterpenoid saponin from the sponge Dictyonella marsilii'. Phytochemistry Letters, 13 :252-255 [Details]
(2014) 'Autumnalamide, a Prenylated Cyclic Peptide from the Cyanobacterium Phormidium autumnale, Acts on SH-SY5Y Cells at the Mitochondrial Level'
Audoin, Coralie,Sanchez, Jon Andoni,Genta-Jouve, Gregory,Alfonso, Amparo,Rios, Laurent,Vale, Carmen,Thomas, Olivier P.,Botana, Luis M. (2014) 'Autumnalamide, a Prenylated Cyclic Peptide from the Cyanobacterium Phormidium autumnale, Acts on SH-SY5Y Cells at the Mitochondrial Level'. Journal of Natural Products, 77 (10):2196-2205 [Details]
(2014) 'Mahorones, highly brominated cyclopentenones from the red alga Asparagopsis taxiformis'
Greff, Stephane,Zubia, Mayalen,Genta-Jouve, Gregory,Massi, Lionel,Perez, Thierry,Thomas, Olivier P. (2014) 'Mahorones, highly brominated cyclopentenones from the red alga Asparagopsis taxiformis'. Journal of Natural Products, 77 (5):1150-1155 [Details]
(2014) 'Volatile Compounds of Viola odorata Absolutes: Identification of Odorant Active Markers to Distinguish Plants Originating from France and Egypt'
Saint-Lary, Laure,Roy, Celine,Paris, Jean-Philippe,Tournayre, Pascal,Berdague, Jean-Louis,Thomas, Olivier P.,Fernandez, Xavier. (2014) 'Volatile Compounds of Viola odorata Absolutes: Identification of Odorant Active Markers to Distinguish Plants Originating from France and Egypt'. Chemistry & Biodiversity, 11 (6):843-860 [Details]
(2014) 'Metabolome consistency: additional parazoanthines from the Mediterranean zoanthid Parazoanthus axinellae'
Audoin, Coralie,Cocandeau, Vincent,Thomas, Olivier P.,Bruschini, Adrien,Holderith, Serge,Genta-Jouve, Gregory. (2014) 'Metabolome consistency: additional parazoanthines from the Mediterranean zoanthid Parazoanthus axinellae'. Metabolites, 4 (2) [Details]
(2014) 'Further insights into brevetoxin metabolism by de Novo radiolabeling'
Calabro, Kevin,Guigonis, Jean-Marie,Teyssie, Jean-Louis,Oberhaensli, Francois,Goudour, Jean-Pierre,Warnau, Michel,Bottein, Marie-Yasmine Dechraoui,Thomas, Olivier P. (2014) 'Further insights into brevetoxin metabolism by de Novo radiolabeling'. Toxins, 6 (6) [Details]
(2014) 'Development of a work-flow for high-performance thin-layer chromatography data processing for untargeted metabolomics'
Audoin, Coralie,Holderith, Serge,Romari, Khadidja,Thomas, Olivier P.,Genta-Jouve, Gregory. (2014) 'Development of a work-flow for high-performance thin-layer chromatography data processing for untargeted metabolomics'. Journal of Planar Chromatography--Modern TLC, 27 (5):328-332 [Details]
(2014) 'Two-dimensional ultra high pressure liquid chromatography quadrupole/time-of-flight mass spectrometry for semi-targeted natural compounds identification'
Genta-Jouve, Gregory,Croue, Julie,Weinberg, Lionel,Cocandeau, Vincent,Holderith, Serge,Bontemps, Nataly,Suzuki, Marcelino,Thomas, Olivier P. (2014) 'Two-dimensional ultra high pressure liquid chromatography quadrupole/time-of-flight mass spectrometry for semi-targeted natural compounds identification'. Phytochemistry Letters, 10 :318-323 [Details]
(2014) 'Environmental solutions for the sustainable production of bioactive natural products from the marine sponge Crambe crambe'
Perez-Lopez, Paula,Ternon, Eva,Gonzalez-Garcia, Sara,Genta-Jouve, Gregory,Feijoo, Gumersindo,Thomas, Olivier P.,Moreira, Teresa. (2014) 'Environmental solutions for the sustainable production of bioactive natural products from the marine sponge Crambe crambe'. Science of the Total Environment, 475 :71-82 [Details]
(2014) 'In vitro antiplasmodial activity, cytotoxicity and chemical profiles of sponge species of Cuban coasts'
Mendiola, Judith,Regalado, Erik L.,Diaz-Garcia, Alexis,Thomas, Olivier P.,Fernandez-Calienes, Ayme,Rodriguez, Hermis,Laguna, Abilio,Valdes, Olga. (2014) 'In vitro antiplasmodial activity, cytotoxicity and chemical profiles of sponge species of Cuban coasts'. Natural Product Research, 28 (5):312-317 [Details]
(2013) 'Ulososides and urabosides - triterpenoid saponins from the Caribbean marine sponge Ectyoplasia ferox'
Colorado, Jhonny,Munoz, Diana,Marquez, Diana,Marquez, Maria Elena,Lopez, Juan,Thomas, Olivier P.,Martinez, Alejandro. (2013) 'Ulososides and urabosides - triterpenoid saponins from the Caribbean marine sponge Ectyoplasia ferox'. Molecules, 18 :2598-2610 [Details]
(2013) 'Sustainable production of biologically active molecules of marine based origin'
Murray, Patrick M.,Moane, Siobhan,Collins, Catherine,Beletskaya, Tanya,Thomas, Olivier P.,Duarte, Alysson W. F.,Nobre, Fernando S.,Owoyemi, Ifeloju O.,Pagnocca, Fernando C.,Sette, L. D.,McHugh, Edward,Causse, Eric,Perez-Lopez, Paula,Feijoo, Gumersindo,Moreira, .T.,Rubiolo, Juan,Leiros, Marta,Botana, Luis M.,Pinteus, Susete,Alves, Celso,Horta, Andre,Pedrosa, Rui,Jeffryes, Clayton,Agathos, Spiros N.,Allewaert, Celine,Verween, Annick,Vyverman, Wim,Laptev, Ivan,Sineoky, Sergei,Bisio, Angela,Manconi, Renata,Ledda, Fabio,Marchi, Mario,Pronzato, Roberto,Walsh, Daniel J. (2013) 'Sustainable production of biologically active molecules of marine based origin'. New Biotechnology, 30 (6):839-850 [Details]
(2013) 'Ligerin, an Antiproliferative Chlorinated Sesquiterpenoid from a Marine-Derived Penicillium Strain'
Vansteelandt, Marieke,Blanchet, Elodie,Egorov, Maxim,Petit, Fabien,Toupet, Loic,Bondon, Arnaud,Monteau, Fabrice,Le Bizec, Bruno,Thomas, Olivier P.,Pouchus, Yves Francois,Le Bot, Ronan,Grovel, Olivier. (2013) 'Ligerin, an Antiproliferative Chlorinated Sesquiterpenoid from a Marine-Derived Penicillium Strain'. Journal of Natural Products, 76 (2):297-301 [Details]
(2013) 'Absolute configuration of the new 3-epi-cladocroic acid from the Mediterranean sponge Haliclona fulva'
Genta-Jouve, Gregory,Thomas, Olivier P. (2013) 'Absolute configuration of the new 3-epi-cladocroic acid from the Mediterranean sponge Haliclona fulva'. Metabolites, 3 (1):24-32 [Details]
(2013) 'Differential Effects of Crambescins and Crambescidin 816 in Voltage-Gated Sodium, Potassium and Calcium Channels in Neurons'
Martin, Victor,Vale, Carmen,Bondu, Stephanie,Thomas, Olivier P.,Vieytes, Mercedes R.,Botana, Luis M. (2013) 'Differential Effects of Crambescins and Crambescidin 816 in Voltage-Gated Sodium, Potassium and Calcium Channels in Neurons'. Chemical Research in Toxicology, 26 (1):169-178 [Details]
(2013) 'Revising the Absolute Configurations of Coatlines via Density Functional Theory Calculations of Electronic Circular Dichroism Spectra'
Genta-Jouve, Gregory,Weinberg, Lionel,Cocandeau, Vincent,Maestro, Yannick,Thomas, Olivier Paul,Holderith, Serge. (2013) 'Revising the Absolute Configurations of Coatlines via Density Functional Theory Calculations of Electronic Circular Dichroism Spectra'. Chirality, 25 (3):180-184 [Details]
(2013) 'Balibalosides, an original family of glucosylated sesterterpenes produced by the Mediterranean sponge Oscarella balibaloi'
Audoin, Coralie,Bonhomme, Dominique,Ivanisevic, Julijana,de, la Cruz Mercedes,Cautain, Bastien,Monteiro, Maria Candida,Reyes, Fernando,Rios, Laurent,Perez, Thierry,Thomas, Olivier P. (2013) 'Balibalosides, an original family of glucosylated sesterterpenes produced by the Mediterranean sponge Oscarella balibaloi'. Marine drugs, 11 (5):1477-89 [Details]
(2013) 'Balibalosides, an original family of glycosylated sesterterpenes produced by the Mediterranean sponge Oscarella balibaloi'
Audoin, Coralie,Bonhomme, Dominique,Ivanisevic, Julijana,de la Cruz, Mercedes,Cautain, Bastien,Monteiro, Maria Candida,Reyes, Fernando,Rios, Laurent,Perez, Thierry,Thomas, Olivier P. (2013) 'Balibalosides, an original family of glycosylated sesterterpenes produced by the Mediterranean sponge Oscarella balibaloi'. Marine Drugs, 11 :1477-1489 [Details]
(2013) 'Additional Cytotoxic Pyridoacridine Alkaloids from the Ascidian Cystodytes violatinctus and Biogenetic Considerations'
Bontemps, Nataly,Gattacceca, Florence,Long, Christophe,Thomas, Olivier P.,Banaigs, Bernard. (2013) 'Additional Cytotoxic Pyridoacridine Alkaloids from the Ascidian Cystodytes violatinctus and Biogenetic Considerations'. Journal of Natural Products, 76 (9):1801-1805 [Details]
(2013) 'Biosynthesis in marine sponges: the radiolabelling strikes back'
Genta-Jouve, Gregory,Thomas, Olivier P. (2013) 'Biosynthesis in marine sponges: the radiolabelling strikes back'. Phytochemistry Reviews, 12 (3):425-434 [Details]
(2013) 'Crambescidin-816 acts as a fungicidal with more potency than crambescidin-800 and -830, inducing cell cycle arrest, increased cell size and apoptosis in Saccharomyces cerevisiae'
Rubiolo, Juan A.,Ternon, Eva,Lopez-Alonso, Henar,Thomas, Olivier P.,Vega, Felix V.,Vieytes, Mercedes R.,Botana, Luis M. (2013) 'Crambescidin-816 acts as a fungicidal with more potency than crambescidin-800 and -830, inducing cell cycle arrest, increased cell size and apoptosis in Saccharomyces cerevisiae'. Marine Drugs, 11 (11) [Details]
(2013) 'Chemical diversity in the scleractinian coral Astroides calycularis'
Cachet, Nadja,Loffredo, Loic,Vicente, Oscar Ocana,Thomas, Olivier P. (2013) 'Chemical diversity in the scleractinian coral Astroides calycularis'. Phytochemistry Letters, 6 (2):205-208 [Details]
(2012) 'Nukuhivensiums, indolo[2,3-a]quinoliziniums from the Marquesan plant Rauvolfia nukuhivensis'
Martin, Nicolas J.,Prado, Soizic,Lecellier, Gael,Thomas, Olivier P.,Raharivelomanana, Phila. (2012) 'Nukuhivensiums, indolo[2,3-a]quinoliziniums from the Marquesan plant Rauvolfia nukuhivensis'. Molecules, 17 :12015-12022 [Details]
(2012) 'Determination of the absolute configuration and evaluation of the in vitro antitumor activity of dilospirane B'
Genta-Jouve, Gregory,Ioannou, Efstathia,Mathieu, Veronique,Bruyere, Celine,Lefranc, Florence,Thomas, Olivier P.,Kiss, Robert,Roussis, Vassilios. (2012) 'Determination of the absolute configuration and evaluation of the in vitro antitumor activity of dilospirane B'. Phytochemistry Letters, 5 (4):747-751 [Details]
(2012) 'Antiparasitic bromotyrosine derivatives from the Caribbean marine sponge Aiolochroia crassa'
Galeano, Elkin,Martinez, Alejandro,Thomas, Olivier P.,Robledo, Sara,Munoz, Diana. (2012) 'Antiparasitic bromotyrosine derivatives from the Caribbean marine sponge Aiolochroia crassa'. Quimica Nova, 35 (6):1189-1193 [Details]
(2012) 'Comparative bioaccumulation kinetics of trace elements in Mediterranean marine sponges'
Genta-Jouve, Gregory,Cachet, Nadja,Oberhansli, Francois,Noyer, Charlotte,Teyssie, Jean-Louis,Thomas, Olivier P.,Lacoue-Labarthe, Thomas. (2012) 'Comparative bioaccumulation kinetics of trace elements in Mediterranean marine sponges'. Chemosphere, 89 (3):340-349 [Details]
(2012) 'Additional bioactive guanidine alkaloids from the Mediterranean sponge Crambe crambe'
Bondu, Stephanie,Genta-Jouve, Gregory,Leiros, Marta,Vale, Carmen,Guigonis, Jean-Marie,Botana, Luis M.,Thomas, Olivier P. (2012) 'Additional bioactive guanidine alkaloids from the Mediterranean sponge Crambe crambe'. RSC Advances, 2 (7):2828-2835 [Details]
(2012) 'Phytochemical analysis and antioxidant capacity of BM-21, a bioactive extract rich in polyphenolic metabolites from the sea grass Thalassia testudinum'
Regalado, Erik L.,Menendez, Roberto,Valdes, Olga,Morales, Ruth A.,Laguna, Abilio,Thomas, Olivier P.,Hernandez, Yasnay,Nogueiras, Clara,Kijjoa, Anake. (2012) 'Phytochemical analysis and antioxidant capacity of BM-21, a bioactive extract rich in polyphenolic metabolites from the sea grass Thalassia testudinum'. Natural Product Communications, 7 (1):47-50 [Details]
(2012) 'Sponge chemical diversity: from biosynthetic pathways to ecological roles'
Genta-Jouve, Gregory,Thomas, Olivier P. (2012) 'Sponge chemical diversity: from biosynthetic pathways to ecological roles'. Advances in marine biology, 62 :183-230 [Details]
(2011) 'Biochemical trade-offs: evidence for ecologically linked secondary metabolism of the sponge Oscarella balibaloi'
Ivanisevic, Julijana,Thomas, Olivier P.,Pedel, Laura,Penez, Nicolas,Ereskovsky, Alexander V.,Culioli, Gerald,Perez, Thierry. (2011) 'Biochemical trade-offs: evidence for ecologically linked secondary metabolism of the sponge Oscarella balibaloi'. PLoS One, 6 (11) [Details]
(2011) 'Acanthifoliosides, minor steroidal saponins from the Caribbean sponge Pandaros acanthifolium'
Regalado, Erik L.,Jimenez-Romero, Carlos,Genta-Jouve, Gregory,Tasdemir, Deniz,Amade, Philippe,Nogueiras, Clara,Thomas, Olivier P. (2011) 'Acanthifoliosides, minor steroidal saponins from the Caribbean sponge Pandaros acanthifolium'. Tetrahedron, 67 (5):1011-1018 [Details]
(2011) 'Antiparasitic bromotyrosine derivatives from the marine sponge Verongula rigida'
Galeano, Elkin,Thomas, Olivier P.,Robledo, Sara,Munoz, Diana,Martinez, Alejandro. (2011) 'Antiparasitic bromotyrosine derivatives from the marine sponge Verongula rigida'. Marine Drugs, 9 :1902-1913 [Details]
(2011) 'Photoprotecting action and phytochemical analysis of a multiple radical scavenger lipophilic fraction obtained from the leaf of the seagrass Thalassia testudinum'
Regalado, Erik L.,Rodriguez, Maria,Menendez, Roberto,Fernandez, Xavier,Hernandez, Ivones,Morales, Ruth A.,Fernandez, Miguel D.,Thomas, Olivier P.,Pino, Jorge A.,Concepcion, Angel R.,Laguna, Abilio. (2011) 'Photoprotecting action and phytochemical analysis of a multiple radical scavenger lipophilic fraction obtained from the leaf of the seagrass Thalassia testudinum'. Photochemistry and Photobiology, 87 (5):1058-1066 [Details]
(2011) 'New Insight into Marine Alkaloid Metabolic Pathways: Revisiting Oroidin Biosynthesis [Erratum to document cited in CA155:609335]'
Genta-Jouve, Gregory,Cachet, Nadja,Holderith, Serge,Oberhaensli, Francois,Teyssie, Jean-Louis,Jeffree, Ross,Al Mourabit, Ali,Thomas, Olivier P. (2011) 'New Insight into Marine Alkaloid Metabolic Pathways: Revisiting Oroidin Biosynthesis [Erratum to document cited in CA155:609335]'. ChemBioChem, 12 (15) [Details]
(2011) 'Antifouling Properties of Simple Indole and Purine Alkaloids from the Mediterranean Gorgonian Paramuricea clavata'
Penez, Nicolas,Culioli, Gerald,Perez, Thierry,Briand, Jean-Francois,Thomas, Olivier P.,Blache, Yves. (2011) 'Antifouling Properties of Simple Indole and Purine Alkaloids from the Mediterranean Gorgonian Paramuricea clavata'. Journal of Natural Products, 74 (10):2304-2308 [Details]
(2011) 'Cytotoxic and hemolytic steroidal glycosides from the Caribbean sponge Pandaros acanthifolium'
Regalado, Erik L.,Turk, Tom,Tasdemir, Deniz,Gorjanc, Manca,Kaiser, Marcel,Thomas, Olivier P.,Fernandez, Rogelio,Amade, Philippe. (2011) 'Cytotoxic and hemolytic steroidal glycosides from the Caribbean sponge Pandaros acanthifolium'. Steroids, 76 (12):1389-1396 [Details]
(2011) 'New Insight into Marine Alkaloid Metabolic Pathways: Revisiting Oroidin Biosynthesis'
Genta-Jouve, Gregory,Cachet, Nadja,Holderith, Serge,Oberhaensli, Francois,Teyssie, Jean-Louis,Jeffree, Ross,Al Mourabit, Ali,Thomas, Olivier P. (2011) 'New Insight into Marine Alkaloid Metabolic Pathways: Revisiting Oroidin Biosynthesis'. ChemBioChem, 12 (15):2298-2301 [Details]
(2011) 'Structure elucidation of the new citharoxazole from the Mediterranean deep-sea sponge Latrunculia (Biannulata) citharistae'
Genta-Jouve, Gregory,Francezon, Nellie,Puissant, Alexandre,Auberger, Patrick,Vacelet, Jean,Perez, Thierry,Fontana, Angelo,Mourabit, Ali Al,Thomas, Olivier P. (2011) 'Structure elucidation of the new citharoxazole from the Mediterranean deep-sea sponge Latrunculia (Biannulata) citharistae'. Magnetic Resonance in Chemistry, 49 (8):533-536 [Details]
(2011) 'Isolation of a bromotyrosine derivative compound of a bioactive fraction from the marine sponge Iotrochota birotulata from the Uraba Gulf (Colombia)'
Marquez, Diana M.,Marquez, Maria E.,Martinez, Alejandro,Thomas, Olivier P. (2011) 'Isolation of a bromotyrosine derivative compound of a bioactive fraction from the marine sponge Iotrochota birotulata from the Uraba Gulf (Colombia)'. Latin American Journal of Pharmacy, 30 (2):392-396 [Details]
(2011) 'Patterns of chemical diversity in the Mediterranean sponge Spongia lamella'
Noyer, Charlotte,Thomas, Olivier P.,Becerro, Mikel A. (2011) 'Patterns of chemical diversity in the Mediterranean sponge Spongia lamella'. PLoS One, 6 (6) [Details]
(2011) 'Metabolic fingerprinting as an indicator of biodiversity: towards understanding inter-specific relationships among Homoscleromorpha sponges'
Ivanisevic, Julijana,Thomas, Olivier P.,Lejeusne, Christophe,Chevaldonne, Pierre,Perez, Thierry. (2011) 'Metabolic fingerprinting as an indicator of biodiversity: towards understanding inter-specific relationships among Homoscleromorpha sponges'. Metabolomics, 7 (2):289-304 [Details]
(2011) 'Lysophospholipids in the Mediterranean Sponge Oscarella tuberculata: Seasonal Variability and Putative Biological Role'
Ivanisevic, Julijana,Perez, Thierry,Ereskovsky, Alexander V.,Barnathan, Gilles,Thomas, Olivier P. (2011) 'Lysophospholipids in the Mediterranean Sponge Oscarella tuberculata: Seasonal Variability and Putative Biological Role'. Journal of Chemical Ecology, 37 (5):537-545 [Details]
(2011) 'Bromopyrrole alkaloids from the Caribbean sponge Agelas cerebrum'
Regalado, Erik L.,Laguna, Abilio,Mendiola, Judith,Thomas, Olivier P.,Nogueiras, Clara. (2011) 'Bromopyrrole alkaloids from the Caribbean sponge Agelas cerebrum'. Quimica Nova, 34 (2):289-291 [Details]
(2011) 'Antinociception produced by Thalassia testudinum extract BM-21 is mediated by the inhibition of acid-sensing ionic channels by the phenolic compound thalassiolin B'
Garateix, Anoland,Salceda, Emilio,Menendez, Roberto,Regalado, Erik L.,Lopez, Omar,Garcia, Teidy,Morales, Ruth A.,Laguna, Abilio,Thomas, Olivier P.,Soto, Enrique. (2011) 'Antinociception produced by Thalassia testudinum extract BM-21 is mediated by the inhibition of acid-sensing ionic channels by the phenolic compound thalassiolin B'. Molecular Pain, 7 [Details]
(2011) 'Dictyotadimer A, a new dissymmetric bis-diterpene from a brown alga of the genus Dictyota'
Viano, Yannick,Bonhomme, Dominique,Ortalo-Magne, Annick,Thomas, Olivier P.,El Hattab, Mohamed,Piovetti, Louis,Blache, Yves,Culioli, Gerald. (2011) 'Dictyotadimer A, a new dissymmetric bis-diterpene from a brown alga of the genus Dictyota'. Tetrahedron Letters, 52 (9):1031-1035 [Details]
(2011) 'Furfuran lignans and a flavone from Artemisia gorgonum Webb and their in vitro activity against Plasmodium falciparum'
Ortet, Risoleta,Prado, Soizic,Regalado, Erik L.,Valeriote, Frederick A.,Media, Joseph,Mendiola, Judith,Thomas, Olivier P. (2011) 'Furfuran lignans and a flavone from Artemisia gorgonum Webb and their in vitro activity against Plasmodium falciparum'. Journal of Ethnopharmacology, 138 (2):637-640 [Details]
(2010) 'Polar alkaloids from the Caribbean marine sponge Niphates digitalis'
Regalado, Erik L.,Mendiola, Judith,Laguna, Abilio,Nogueiras, Clara,Thomas, Olivier P. (2010) 'Polar alkaloids from the Caribbean marine sponge Niphates digitalis'. Natural Product Communications, 5 (8):1187-1190 [Details]
(2010) 'Composition and Biological Properties of the Volatile Oil of Artemisia gorgonum Webb'
Ortet, Risoleta,Thomas, Olivier P.,Regalado, Erik L.,Pino, Jorge A.,Filippi, Jean-Jacques,Fernandez, Miguel D. (2010) 'Composition and Biological Properties of the Volatile Oil of Artemisia gorgonum Webb'. Chemistry & Biodiversity, 7 (5):1325-1332 [Details]
(2010) 'Antiprotozoal Steroidal Saponins from the Marine Sponge Pandaros acanthifolium'
Regalado, Erik L.,Tasdemir, Deniz,Kaiser, Marcel,Cachet, Nadja,Amade, Philippe,Thomas, Olivier P. (2010) 'Antiprotozoal Steroidal Saponins from the Marine Sponge Pandaros acanthifolium'. Journal of Natural Products, 73 (8):1404-1410 [Details]
(2009) 'Njaoaminiums A, B, and C: cyclic 3-alkylpyridinium salts from the marine sponge Reniera sp'
Laville, Remi,Genta-Jouve, Gregory,Urda, Carlos,Fernandez, Rogelio,Thomas, Olivier P.,Reyes, Fernando,Amade, Philippe. (2009) 'Njaoaminiums A, B, and C: cyclic 3-alkylpyridinium salts from the marine sponge Reniera sp'. Molecules, 14 (11):4716-4724 [Details]
(2009) 'Composition and antioxidant properties of the essential oil of the endemic cape verdean Satureja forbesii'
Ortet, Risoleta,Regalado, Erik L.,Thomas, Olivier P.,Pino, Jorge A.,Fernandez, Miguel D.,Filippi, Jean-Jacques. (2009) 'Composition and antioxidant properties of the essential oil of the endemic cape verdean Satureja forbesii'. Natural Product Communications, 4 (9):1277-1280 [Details]
(2009) 'Bioactive Guanidine Alkaloids from two Caribbean Marine Sponges'
Laville, Remi,Thomas, Olivier P.,Berrue, Fabrice,Marquez, Diana,Vacelet, Jean,Amade, Philippe. (2009) 'Bioactive Guanidine Alkaloids from two Caribbean Marine Sponges'. Journal of Natural Products, 72 (9):1589-1594 [Details]
(2009) 'Parazoanthines A-E, Hydantoin Alkaloids from the Mediterranean Sea Anemone Parazoanthus axinellae'
Cachet, Nadja,Genta-Jouve, Gregory,Regalado, Erik L.,Mokrini, Redouane,Amade, Philippe,Culioli, Gerald,Thomas, Olivier P. (2009) 'Parazoanthines A-E, Hydantoin Alkaloids from the Mediterranean Sea Anemone Parazoanthus axinellae'. Journal of Natural Products, 72 (9):1612-1615 [Details]
(2009) 'Steroidal glycosides from the marine sponge Pandaros acanthifolium'
Cachet, Nadja,Regalado, Erik L.,Genta-Jouve, Gregory,Mehiri, Mohamed,Amade, Philippe,Thomas, Olivier P. (2009) 'Steroidal glycosides from the marine sponge Pandaros acanthifolium'. Steroids, 74 (9):746-750 [Details]
(2009) '3-Alkylpyridinium salts from Haplosclerida marine sponges: isolation, structure elucidations, and biosynthetic considerations'
Laville, Remi,Amade, Philippe,Thomas, Olivier P. (2009) '3-Alkylpyridinium salts from Haplosclerida marine sponges: isolation, structure elucidations, and biosynthetic considerations'. Pure and Applied Chemistry, 81 (6):1033-1040 [Details]

Book Chapters

  Year Publication
(2017) 'Current Status and Perspectives in Marine Biodiscovery'
Firsova D., Mahajan N., Solanki H., Morrow C., Thomas O.P. (2017) 'Current Status and Perspectives in Marine Biodiscovery' In: Bioprospecting. Topics in Biodiversity and Conservation. Vol 16. Cham: Springer. [Details]
(2016) 'Metabolomic Contributions to Chemical Ecology'
Philippe Potin , Florence Nicolè, Olivier P. Thomas (2016) 'Metabolomic Contributions to Chemical Ecology' In: Chemical Ecology. Hoboken, NJ, USA: John Wiley & Sons, Inc.. [DOI] [Details]
(2014) 'Toxins from marine invertebrates'
Ternon, Eva,Thomas, Olivier P. (2014) 'Toxins from marine invertebrates' In: Seafood Freshwater Toxins (3rd Ed.). Boca Raton, FL: CRC Press. [Details]
(2011) 'Polyketide assembly mimics and biomimetic access to aromatic rings'
Genta-Jouve, Gregory,Antoniotti, Sylvain,Thomas, Olivier P. (2011) 'Polyketide assembly mimics and biomimetic access to aromatic rings' In: Biomimetic Organic Synthesis. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA. [Details]

Languages

  Language
Spanish
French
English

Reviews

  Journal Role
Journal Of Natural Products Reviewer
Polar Biology Reviewer
Scientific Reports Editoral Board
Tetrahedron Reviewer
Frontiers In Ecology And The Environment Editoral Board
Phytochemistry Reviewer
Planta Medica Reviewer
Organic Letters Reviewer
Plos One Reviewer
Journal of chemical ecology Reviewer

Current Postgraduate Students (Research)

  Student Degree Type Type
Paul Guillen Mena Doctorate - Structured PhD (Science) Supervisor
Hiren Solanki Doctorate - Structured PhD (Science) Supervisor

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
4th Year BSC and BPC Bioorganic Chemistry CH4108 and 4104 Structure Elucidation by NMR
3rd year Chemistry Nuclear Magnetic Resonance CH326
3rd year Chemistry Experimental Chemistry CH333 Nuclear Magnetic Resonance
3rd Year BSc Natural Products and Drugs CH332 Metabolic Pathways
2nd Year BSc Separation science and water chemistry CH205
2nd Year BSc Organic Chemistry CH202 Practicals
2nd Year BPS Plant Natural Products BPS3105 Isolation and purification

Internal Collaborators

  Name Description of Collaboration
Louise Allcock
SFI Grant
Grace McCormack
Common interest in the the application of metabolomic approaches to understand the systematics of Haliclona sponges
Paul MURPHY
Total synthesis of Marine natural products
Abhay PANDIT
CURAM-Biomaterials and medical devices

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
Jeffrey FISHER Marine Institute IRELAND
Shellfish toxins and Marine Biodiscovery
Alan DOBSON UCC IRELAND
Marine microbes and metagenomics
Gregory Genta-Jouve University Paris Descartes FRANCE
Determination of the stereochemistry of natural products and environmental metabolomics
Erwan Poupon Universite Paris Sud FRANCE
Study of sponge metabolic pathways
Thierry Perez IMBE Marseille FRANCE
Multidiscilpinary approach in sponge ecology and chemical ecology
Luis Botana Universidad de Santiago de Compostella SPAIN
Biological applications of our marine natural compounds
Fernando REYES Fundacion Medina SPAIN
antimicrobial bioassays
Bassam Soussi Mabiotech OMAN
Omani sponge natural products for the pharmaceutical industry
Jenny Rodriguez CENAIM-ESPOL ECUADOR
Natural Product Chemistry
Howard JUNCA Microbiomas COLOMBIA
Omics for the classification of sponges and metabolic pathways
Mayalen Zubia University French Polynesia FRANCE
Chemical ecology of cyanobacteria from the Pacific
Claude Payri UMR Entropie, IRD New Caledonia FRANCE
Chemical ecology of Pacific macroalgae