Prof. Donal Leech

B.SC., PH.D

Contact Details

Personal Professor
Personal Prof School of Chemisty
Dean, College of Science
Room 209 Arts/Science Building
NUI Galway

T: Ext. 3615
E: donal.leech@nuigalway.ie
 
researcher

Biography

Current Positions:
Dean, College of Science, NUI Galway
Personal Professor, School of Chemistry, NUI Galway
Director, Biomolecular Electronics Research Laboratory, NUI Galway 

Biographical Sketch

  • NIHED (now DCU): B.Sc. in Analytical Science, 1988
  • Dublin City University: Ph.D (M.R. Smyth and J.G Vos with visit to J. Wang in NMSU, now at Univ. of San Diego), 1991 
  • University of Hawaii: Post-doctoral researcher (G.A. Rechnitz), 1991
  • Université de Montréal: Assistant Professor,1993
  • NUI Galway: Lecturer/Senior Lecturer/Professor, 1997-present
  • Ecole Normale Superieure, Paris: Visiting Academic (C. Amatore), 2003
  • University of New South Wales, Sydney: Senior Visitor (J.J. Gooding), 2009
  • Canterbury University, Christchurch, NZ: RSC JWT Jones Visiting Fellow (A. Downard), 2009

Research Interests

The Biomolecular Electronics Research Laboratory, Director Prof. Dónal Leech, was established in NUI, Galway in 1997.

Research in the laboratory focuses on preparation and characterisation of electron-transfer catalysts and modified electrode surfaces directed to eventual application as biomolecular electrochemical devices (sensors and fuel cell electrodes).

This research is undertaken by a group consisting of post-doctoral, doctoral, masters and undergraduate researchers working with collaborating partners within NUIG (Paul Kavanagh, Vincent O'Flaherty, Maeve Duffy, Florence Abrams), nationally and internationally (see joint publications for details).

The research laboratory is located in the Ryan Institute of the National University of Ireland Galway (NUIG), and the laboratory is affiliated to the School of Chemistry and National Centre for Biomedical Engineering Sciences.

The fundamental reactions that form the basis of most of our studies are electron transfer reactions. We have a particular interest in electron transfer reactions at the solid/liquid interface and in harnessing biomolecular electron transfer events. The research programme is aimed at developing eventual applications in bioelectrochemical diagnostics and sensors, biomolecular interaction platforms, biofuel cell prototypes, bio- and electrochemical bleaching methodologies, and trace metal monitoring systems in ocean environments. We have in addition a research effort that seeks to underpin these areas of application, focused on synthesis and characterisation of electrode modifiers, separations science and surface analytical techniques, and electrochemical and biochemical methods. Should you require any further information on our research programme please browse our publications, or contact Prof. Dónal Leech

Research Projects

  Project Start Date End Date
IRC POSTGRADUATE SCHOLARSHIP 2016 RICHARD BENNETT - Optimisation of electrode surface chemistry for fuel cell application 01-OCT-16 30-SEP-19
IRC Postdoctoral Fellowship 2016 Kellie Adamson - HELIOS: Light Activated Drug Delivery System 01-OCT-16 30-SEP-18
Bioelectroammonia 01-JUN-15 31-MAY-18
BIOENERGY DONAL LEECH 01-OCT-13 30-SEP-17
PROTEIN BIOMARKER ARRAYS FOR PERSONALISED TREATMENT OF PROSTATE CANCER D LEECH 01-APR-14 31-MAR-18
BIOLOGICALLY MEDIATED SUSTAINABLE ENERGY D LEECH ROG080 085 04-DEC-06 05-OCT-16
DEVELOPMENT OF A BIOLOGICAL OXYGEN DEMAND MONITORING SYSTEM FOR WASTEWARTERS TIDA D LEECH 01-JAN-13 31-AUG-16
IRC EMPOWER RAGHAVULU SAPIREDDY DONAL LEECH 01-NOV-12 31-OCT-14
IRCSET ERA CHEMISTRY DONAL LEECH 01-JAN-10 08-JUL-14
EU FP7 NMP4 SL 2009 229255 DONAL LEECH 3D NANOBIODEVICE 01-JUL-09 30-JUN-13
EU BIO-MEDNANO NMP4-CT-2006-017350 DONAL LEECH 01-JUL-06 28-FEB-11
EPA ENVIRONMENTAL DIAGNOSTICS DONAL LEECH 01-OCT-06 31-DEC-14
EPA RTDI DOCTORAL SCHOLARSHIP LEECH 01-SEP-02 30-JUN-07
EI IF 2001 033 BIOPOWER DONAL LEECH 01-DEC-01 30-MAR-05
940 EU PUBLIER CEP 599 LEECH 01-SEP-00 14-DEC-05
940 EU QLK3 CT2000 1481 LEECH 01-OCT-00 16-DEC-05
930 ENT IR SC98 444 RECEPTOR ASSAY LEECH 01-OCT-98 30-APR-04

Peer Reviewed Journals

  Year Publication
(2016) 'Comparative proteomics implicates a role for multiple secretion systems in electrode-respiring Geobacter sulfurreducens biofilms'
1. Kavanagh P, Botting CH, Jana P, Leech D and Abram, F (2016) 'Comparative proteomics implicates a role for multiple secretion systems in electrode-respiring Geobacter sulfurreducens biofilms'. Journal Of Proteome Research, [DOI] [Details]
(2016) 'Nitrogenase bioelectrocatalysis: heterogeneous ammonia and hydrogen production by MoFe protein'
Milton, RD,Abdellaoui, S,Khadka, N,Dean, DR,Leech, D,Seefeldt, LC,Minteer, SD (2016) 'Nitrogenase bioelectrocatalysis: heterogeneous ammonia and hydrogen production by MoFe protein'. Energy & Environmental Science, 9 :2550-2554 [DOI] [Details]
(2016) 'Fully Enzymatic Membraneless GlucoselOxygen Fuel Cell That Provides 0.275 mA cm(-2) in 5 mM Glucose, Operates in Human Physiological Solutions, and Powers Transmission of Sensing Data'
Conghaile, PO,Falk, M,MacAodha, D,Yakovleva, ME,Gonaus, C,Peterbauer, CK,Gorton, L,Shleev, S,Leech, D (2016) 'Fully Enzymatic Membraneless GlucoselOxygen Fuel Cell That Provides 0.275 mA cm(-2) in 5 mM Glucose, Operates in Human Physiological Solutions, and Powers Transmission of Sensing Data'. Analytical Chemistry, 88 :2156-2163 [DOI] [Details]
(2015) 'A glucose anode for enzymatic fuel cells optimized for current production under physiological conditions using a design of experiment approach'
Kumar, R,Leech, D (2015) 'A glucose anode for enzymatic fuel cells optimized for current production under physiological conditions using a design of experiment approach'. Bioelectrochemistry, 106 :41-46 [DOI] [Details]
(2015) 'Photoelectrochemical Wiring of Paulschulzia pseudovolvox (Algae) to Osmium Polymer Modified Electrodes for Harnessing Solar Energy'
Hasan, K,Cevik, E,Sperling, E,Packer, MA,Leech, D,Gorton, L (2015) 'Photoelectrochemical Wiring of Paulschulzia pseudovolvox (Algae) to Osmium Polymer Modified Electrodes for Harnessing Solar Energy'. Advanced Energy Materials, 5 [DOI] [Details]
(2015) 'Glucose oxidation by osmium redox polymer mediated enzyme electrodes operating at low potential and in oxygen, for application to enzymatic fuel cells'
Osadebe, I,Conghaile, PO,Kavanagh, P,Leech, D (2015) 'Glucose oxidation by osmium redox polymer mediated enzyme electrodes operating at low potential and in oxygen, for application to enzymatic fuel cells'. Electrochimica Acta, 182 :320-326 [DOI] [Details]
(2015) 'Electrochemical Communication Between Electrodes and Rhodobacter capsulatus Grown in Different Metabolic Modes'
Hasan, K,Reddy, KVR,Essmann, V,Gorecki, K,Conghaile, PO,Schuhmann, W,Leech, D,Hagerhall, C,Gorton, L (2015) 'Electrochemical Communication Between Electrodes and Rhodobacter capsulatus Grown in Different Metabolic Modes'. Electroanalysis, 27 :118-127 [DOI] [Details]
(2015) 'Engineering of pyranose dehydrogenase for application to enzymatic anodes in biofuel cells'
Yakovleva, ME,Gonaus, C,Schropp, K,OConghaile, P,Leech, D,Peterbauer, CK,Gorton, L (2015) 'Engineering of pyranose dehydrogenase for application to enzymatic anodes in biofuel cells'. Physical Chemistry Chemical Physics, 17 :9074-9081 [DOI] [Details]
(2015) 'Photocurrent Generation from Thylakoid Membranes on Osmium-Redox-Polymer-Modified Electrodes'
Hamidi, H,Hasan, K,Emek, SC,Dilgin, Y,Akerlund, HE,Albertsson, PA,Leech, D,Gorton, L (2015) 'Photocurrent Generation from Thylakoid Membranes on Osmium-Redox-Polymer-Modified Electrodes'. Chemsuschem, 8 :990-993 [DOI] [Details]
(2014) 'Composite Material Based on Macroporous Polyaniline and Osmium Redox Complex for Biosensor Development'
Antiochia, R,Mazzei, F,Gorton, L,Leech, D,Favero, G (2014) 'Composite Material Based on Macroporous Polyaniline and Osmium Redox Complex for Biosensor Development'. Electroanalysis, 26 :1623-1630 [DOI] [Details]
(2014) 'Coupling of Amine-Containing Osmium Complexes and Glucose Oxidase with Carboxylic Acid Polymer and Carbon Nanotube Matrix to Provide Enzyme Electrodes for Glucose Oxidation'
Kumar, R,Leech, D (2014) 'Coupling of Amine-Containing Osmium Complexes and Glucose Oxidase with Carboxylic Acid Polymer and Carbon Nanotube Matrix to Provide Enzyme Electrodes for Glucose Oxidation'. Journal Of The Electrochemical Society, 161 :3005-3010 [DOI] [Details]
(2014) 'Self-Powered Wireless Carbohydrate/Oxygen Sensitive Biodevice Based on Radio Signal Transmission'
Falk, M,Alcalde, M,Bartlett, PN,De Lacey, AL,Gorton, L,Gutierrez-Sanchez, C,Haddad, R,Kilburn, J,Leech, D,Ludwig, R,Magner, E,Mate, DM,Conghaile, PO,Ortiz, R,Pita, M,Poller, S,Ruzgas, T,Salaj-Kosla, U,Schuhmann, W,Sebelius, F,Shao, ML,Stoica, L,Sygmund, C,Tilly, J,Toscano, MD,Vivekananthan, J,Wright, E,Shleev, S (2014) 'Self-Powered Wireless Carbohydrate/Oxygen Sensitive Biodevice Based on Radio Signal Transmission'. Plos One, 9 [DOI] [Details]
(2014) 'Immobilisation of Alkylamine-Functionalised Osmium Redox Complex on Glassy Carbon using Electrochemical Oxidation'
Kumar, R,Leech, D (2014) 'Immobilisation of Alkylamine-Functionalised Osmium Redox Complex on Glassy Carbon using Electrochemical Oxidation'. Electrochimica Acta, 140 :209-216 [DOI] [Details]
(2014) 'Effect of Multi-Walled Carbon Nanotubes on Glucose Oxidation by Glucose Oxidase or a Flavin-Dependent Glucose Dehydrogenase in Redox-Polymer-Mediated Enzymatic Fuel Cell Anodes'
Osadebe, I,Leech, D (2014) 'Effect of Multi-Walled Carbon Nanotubes on Glucose Oxidation by Glucose Oxidase or a Flavin-Dependent Glucose Dehydrogenase in Redox-Polymer-Mediated Enzymatic Fuel Cell Anodes'. Chemelectrochem, 1 :1988-1993 [DOI] [Details]
(2014) 'Photo-electrochemical communication between cyanobacteria (Leptolyngbia sp.) and osmium redox polymer modified electrodes'
Hasan, K,Yildiz, HB,Sperling, E,Conghaile, PO,Packer, MA,Leech, D,Hagerhall, C,Gorton, L (2014) 'Photo-electrochemical communication between cyanobacteria (Leptolyngbia sp.) and osmium redox polymer modified electrodes'. Physical Chemistry Chemical Physics, 16 :24676-24680 [DOI] [Details]
(2013) 'Tethering Osmium Complexes within Enzyme Films on Electrodes to Provide a Fully Enzymatic Membrane-Less Glucose/Oxygen Fuel Cell'
Conghaile, PO,MacAodha, D,Egan, B,Kavanagh, P,Leech, D (2013) 'Tethering Osmium Complexes within Enzyme Films on Electrodes to Provide a Fully Enzymatic Membrane-Less Glucose/Oxygen Fuel Cell'. Journal Of The Electrochemical Society, 160 :3165-3170 [DOI] [Details]
(2013) 'Mediated glucose enzyme electrodes by cross-linking films of osmium redox complexes and glucose oxidase on electrodes'
Conghaile, PO,Kamireddy, S,MacAodha, D,Kavanagh, P,Leech, D (2013) 'Mediated glucose enzyme electrodes by cross-linking films of osmium redox complexes and glucose oxidase on electrodes'. Analytical And Bioanalytical Chemistry, 405 :3807-3812 [DOI] [Details]
(2013) 'Mediated electron transfer of cellobiose dehydrogenase and glucose oxidase at osmium polymer-modified nanoporous gold electrodes'
Salaj-Kosla, U,Scanlon, MD,Baumeister, T,Zahma, K,Ludwig, R,Conghaile, PO,MacAodha, D,Leech, D,Magner, E (2013) 'Mediated electron transfer of cellobiose dehydrogenase and glucose oxidase at osmium polymer-modified nanoporous gold electrodes'. Analytical And Bioanalytical Chemistry, 405 :3823-3830 [DOI] [Details]
(2013) 'Comparison of Glucose Oxidation by Crosslinked Redox Polymer Enzyme Electrodes Containing Carbon Nanotubes and a Range of Glucose Oxidising Enzymes'
MacAodha, D,Conghaile, PO,Egan, B,Kavanagh, P,Sygmund, C,Ludwig, R,Leech, D (2013) 'Comparison of Glucose Oxidation by Crosslinked Redox Polymer Enzyme Electrodes Containing Carbon Nanotubes and a Range of Glucose Oxidising Enzymes'. Electroanalysis, 25 :94-100 [DOI] [Details]
(2013) 'Mediated electron transfer in glucose oxidising enzyme electrodes for application to biofuel cells: recent progress and perspectives'
Kavanagh, P,Leech, D (2013) 'Mediated electron transfer in glucose oxidising enzyme electrodes for application to biofuel cells: recent progress and perspectives'. Physical Chemistry Chemical Physics, 15 :4859-4869 [DOI] [Details]
(2013) 'Electrochemical communication between heterotrophically grown Rhodobacter capsulatus with electrodes mediated by an osmium redox polymer'
Hasan, K,Patil, SA,Gorecki, K,Leech, D,Hagerhall, C,Gorton, L (2013) 'Electrochemical communication between heterotrophically grown Rhodobacter capsulatus with electrodes mediated by an osmium redox polymer'. Bioelectrochemistry, 93 :30-36 [DOI] [Details]
(2013) 'Further Insights into the Catalytical Properties of Deglycosylated Pyranose Dehydrogenase from Agaricus meleagris Recombinantly Expressed in Pichia pastoris'
Yakovleva, ME,Killyeni, A,Seubert, O,Conghaile, PO,MacAodha, D,Leech, D,Gonaus, C,Popescu, IC,Peterbauer, CK,Kjellstrom, S,Gorton, L (2013) 'Further Insights into the Catalytical Properties of Deglycosylated Pyranose Dehydrogenase from Agaricus meleagris Recombinantly Expressed in Pichia pastoris'. Analytical Chemistry, 85 :9852-9858 [DOI] [Details]
(2013) 'Catalytic response of microbial biofilms grown under fixed anode potentials depends on electrochemical cell configuration'
Kumar, A,Siggins, A,Katuri, K,Mahony, T,O'Flaherty, V,Lens, P,Leech, D (2013) 'Catalytic response of microbial biofilms grown under fixed anode potentials depends on electrochemical cell configuration'. Chemical Engineering Journal, 230 :532-536 [DOI] [Details]
(2013) 'Arylamine functionalization of carbon anodes for improved microbial electrocatalysis'
Kumar, A,Conghaile, PO,Katuri, K,Lens, P,Leech, D (2013) 'Arylamine functionalization of carbon anodes for improved microbial electrocatalysis'. Rsc Advances, 3 :18759-18761 [DOI] [Details]
(2013) 'Membraneless Glucose/Oxygen Enzymatic Fuel Cells Using Redox Hydrogel Films Containing Carbon Nanotubes'
MacAodha, D,Conghaile, PO,Egan, B,Kavanagh, P,Leech, D (2013) 'Membraneless Glucose/Oxygen Enzymatic Fuel Cells Using Redox Hydrogel Films Containing Carbon Nanotubes'. Chemphyschem, 14 :2302-2307 [DOI] [Details]
(2013) 'Optimization of a Membraneless Glucose/Oxygen Enzymatic Fuel Cell Based on a Bioanode with High Coulombic Efficiency and Current Density'
Shao, ML,Zafar, MN,Falk, M,Ludwig, R,Sygmund, C,Peterbauer, CK,Guschin, DA,MacAodha, D,Conghaile, PO,Leech, D,Toscano, MD,Shleev, S,Schuhmann, W,Gorton, L (2013) 'Optimization of a Membraneless Glucose/Oxygen Enzymatic Fuel Cell Based on a Bioanode with High Coulombic Efficiency and Current Density'. Chemphyschem, 14 :2260-2269 [DOI] [Details]
(2013) 'Coupling osmium complexes to epoxy-functionalised polymers to provide mediated enzyme electrodes for glucose oxidation'
Conghaile, PO,Poller, S,MacAodha, D,Schuhmann, W,Leech, D (2013) 'Coupling osmium complexes to epoxy-functionalised polymers to provide mediated enzyme electrodes for glucose oxidation'. Biosensors & Bioelectronics, 43 :30-37 [DOI] [Details]
(2012) 'Electron-Transfer Studies with a New Flavin Adenine Dinucleotide Dependent Glucose Dehydrogenase and Osmium Polymers of Different Redox Potentials'
Zafar, MN,Wang, XJ,Sygmund, C,Ludwig, R,Leech, D,Gorton, L (2012) 'Electron-Transfer Studies with a New Flavin Adenine Dinucleotide Dependent Glucose Dehydrogenase and Osmium Polymers of Different Redox Potentials'. Analytical Chemistry, 84 :334-341 [DOI] [Details]
(2012) 'A glucose/oxygen enzymatic fuel cell based on redox polymer and enzyme immobilisation at highly-ordered macroporous gold electrodes'
Boland, S,Leech, D (2012) 'A glucose/oxygen enzymatic fuel cell based on redox polymer and enzyme immobilisation at highly-ordered macroporous gold electrodes'. Analyst, 137 :113-117 [DOI] [Details]
(2012) 'Acetic anhydride mediated condensation of aromatic o-diacid dichlorides with benzimidazoles to provide electro-reducible p-dione adducts'
Eamonn Joyce, Paul Kavanagh, Dónal Leech, Jolanta Karpinska, Patrick McArdle, Fawaz Aldabbagh (2012) 'Acetic anhydride mediated condensation of aromatic o-diacid dichlorides with benzimidazoles to provide electro-reducible p-dione adducts'. Tetrahedron Letters, 53 :3788-3791 [DOI] [Details]
(2012) 'Charge Transport through Geobacter sulfurreducens Biofilms Grown on Graphite Rods'
Katuri, KP,Rengaraj, S,Kavanagh, P,O'Flaherty, V,Leech, D (2012) 'Charge Transport through Geobacter sulfurreducens Biofilms Grown on Graphite Rods'. Langmuir, 28 :7904-7913 [DOI] [Details]
(2012) 'Characterization of different FAD-dependent glucose dehydrogenases for possible use in glucose-based biosensors and biofuel cells'
Zafar, MN,Beden, N,Leech, D,Sygmund, C,Ludwig, R,Gorton, L (2012) 'Characterization of different FAD-dependent glucose dehydrogenases for possible use in glucose-based biosensors and biofuel cells'. Analytical And Bioanalytical Chemistry, 402 :2069-2077 [DOI] [Details]
(2012) 'A mediated glucose/oxygen enzymatic fuel cell based on printed carbon inks containing aldose dehydrogenase and laccase as anode and cathode'
Jenkins, P,Tuurala, S,Vaari, A,Valkiainen, M,Smolander, M,Leech, D (2012) 'A mediated glucose/oxygen enzymatic fuel cell based on printed carbon inks containing aldose dehydrogenase and laccase as anode and cathode'. Enzyme And Microbial Technology, 50 :181-187 [DOI] [Details]
(2012) 'Characterization of Nanoporous Gold Electrodes for Bioelectrochemical Applications'
Scanlon, MD,Salaj-Kosla, U,Belochapkine, S,MacAodha, D,Leech, D,Ding, Y,Magner, E (2012) 'Characterization of Nanoporous Gold Electrodes for Bioelectrochemical Applications'. Langmuir, 28 :2251-2261 [DOI] [Details]
(2012) 'A comparison of glucose oxidase and aldose dehydrogenase as mediated anodes in printed glucose/oxygen enzymatic fuel cells using ABTS/laccase cathodes'
Jenkins, P,Tuurala, S,Vaari, A,Valkiainen, M,Smolander, M,Leech, D (2012) 'A comparison of glucose oxidase and aldose dehydrogenase as mediated anodes in printed glucose/oxygen enzymatic fuel cells using ABTS/laccase cathodes'. Bioelectrochemistry, 87 :172-177 [DOI] [Details]
(2012) 'Microbial analysis of anodic biofilm in a microbial fuel cell using slaughterhouse wastewater'
Katuri, KP,Enright, AM,O'Flaherty, V,Leech, D (2012) 'Microbial analysis of anodic biofilm in a microbial fuel cell using slaughterhouse wastewater'. Bioelectrochemistry, 87 :164-171 [DOI] [Details]
(2012) 'Does bioelectrochemical cell configuration and anode potential affect biofilm response?'
Kumar, A,Katuri, K,Lens, P,Leech, D (2012) 'Does bioelectrochemical cell configuration and anode potential affect biofilm response?'. Biochemical Society Transactions, 40 :1308-1314 [DOI] [Details]
(2012) 'Recombinant pyranose dehydrogenase-A versatile enzyme possessing both mediated and direct electron transfer'
Yakovleva, ME,Killyeni, A,Ortiz, R,Schulz, C,MacAodha, D,Conghaile, PO,Leech, D,Popescu, IC,Gonaus, C,Peterbauer, CK,Gorton, L (2012) 'Recombinant pyranose dehydrogenase-A versatile enzyme possessing both mediated and direct electron transfer'. Electrochemistry Communications, 24 :120-122 [DOI] [Details]
(2012) 'Improved microbial electrocatalysis with osmium polymer modified electrodes'
Patil, SA,Hasan, K,Leech, D,Hagerhall, C,Gorton, L (2012) 'Improved microbial electrocatalysis with osmium polymer modified electrodes'. Chemical Communications, 48 :10183-10185 [DOI] [Details]
(2012) 'Electrochemical communication between microbial cells and electrodes via osmium redox systems'
Hasan, K,Patil, SA,Leech, D,Hagerhall, C,Gorton, L (2012) 'Electrochemical communication between microbial cells and electrodes via osmium redox systems'. Biochemical Society Transactions, 40 :1330-1335 [DOI] [Details]
(2012) 'Crosslinked redox polymer enzyme electrodes containing carbon nanotubes for high and stable glucose oxidation current'
MacAodha, D,Ferrer, ML,Conghaile, PO,Kavanagh, P,Leech, D (2012) 'Crosslinked redox polymer enzyme electrodes containing carbon nanotubes for high and stable glucose oxidation current'. Physical Chemistry Chemical Physics, 14 :14667-14672 [DOI] [Details]
(2012) 'EFFECT OF ENZYME DEGLYCOSYLATION ON THE AMPEROMETRIC DETECTION OF GLUCOSE AT PDH-MODIFIED ELECTRODE'
Killyeni, A,Yakovleva, ME,Peterbauer, CK,Leech, D,Gorton, L,Popescu, IC (2012) 'EFFECT OF ENZYME DEGLYCOSYLATION ON THE AMPEROMETRIC DETECTION OF GLUCOSE AT PDH-MODIFIED ELECTRODE'. Studia Universitatis Babes-Bolyai Chemia, 57 :87-99 [Details]
(2011) 'Oxygen Electroreduction Catalyzed by Bilirubin Oxidase Does Not Release Hydrogen Peroxide'
Tonda-Mikiela, P,Habrioux, A,Boland, S,Servat, K,Tingry, S,Kavanagh, P,Napporn, TW,Leech, D,Kokoh, KB (2011) 'Oxygen Electroreduction Catalyzed by Bilirubin Oxidase Does Not Release Hydrogen Peroxide'. Electrocatalysis, 2 :268-272 [DOI] [Details]
(2011) 'A membrane-less enzymatic fuel cell with layer-by-layer assembly of redox polymer and enzyme over graphite electrodes'
Rengaraj, S,Mani, V,Kavanagh, P,Rusling, J,Leech, D (2011) 'A membrane-less enzymatic fuel cell with layer-by-layer assembly of redox polymer and enzyme over graphite electrodes'. Chemical Communications, 47 :11861-11863 [DOI] [Details]
(2011) 'Electricity generation in single-chamber microbial fuel cells using a carbon source sampled from anaerobic reactors utilizing grass silage'
Catal, T,Cysneiros, D,O'Flaherty, V,Leech, D (2011) 'Electricity generation in single-chamber microbial fuel cells using a carbon source sampled from anaerobic reactors utilizing grass silage'. Bioresource Technology, 102 :404-410 [DOI] [Details]
(2011) 'A comparison of redox polymer and enzyme co-immobilization on carbon electrodes to provide membrane-less glucose/O-2 enzymatic fuel cells with improved power output and stability'
Rengaraj, S,Kavanagh, P,Leech, D (2011) 'A comparison of redox polymer and enzyme co-immobilization on carbon electrodes to provide membrane-less glucose/O-2 enzymatic fuel cells with improved power output and stability'. Biosensors & Bioelectronics, 30 :294-299 [DOI] [Details]
(2011) 'Three-dimensional microchanelled electrodes in flow-through configuration for bioanode formation and current generation'
Katuri, K,Ferrer, ML,Gutierrez, MC,Jimenez, R,del Monte, F,Leech, D (2011) 'Three-dimensional microchanelled electrodes in flow-through configuration for bioanode formation and current generation'. Energy & Environmental Science, 4 :4201-4210 [DOI] [Details]
(2010) 'Substantial Influence of Temperature on Anchoring of Gold-Nanoparticle Monolayer for Performance of DNA Biosensors'
Nowicka, AM,Kowalczyk, A,Donten, M,Leech, D,Hepel, M,Stojek, Z (2010) 'Substantial Influence of Temperature on Anchoring of Gold-Nanoparticle Monolayer for Performance of DNA Biosensors'. Electroanalysis, 22 :2323-2329 [DOI] [Details]
(2010) 'Geobacter sulfurreducens biofilms developed under different growth conditions on glassy carbon electrodes: insights using cyclic voltammetry'
Katuri, KP,Kavanagh, P,Rengaraj, S,Leech, D (2010) 'Geobacter sulfurreducens biofilms developed under different growth conditions on glassy carbon electrodes: insights using cyclic voltammetry'. Chemical Communications, 46 :4758-4760 [DOI] [Details]
(2010) 'Preparation and reactivity of carboxylic acid-terminated boron-doped diamond electrodes'
Niedziolka-Jonsson, J., Boland, S., Leech, D., Boukherroub, R., Szunerits, S. (2010) 'Preparation and reactivity of carboxylic acid-terminated boron-doped diamond electrodes'. Electrochimica Acta, 55 (3) [Details]
(2010) 'Wiring of pyranose dehydrogenase with osmium polymers of different redox potentials'
Zafar, MN,Tasca, F,Boland, S,Kujawa, M,Patel, I,Peterbauer, CK,Leech, D,Gorton, L (2010) 'Wiring of pyranose dehydrogenase with osmium polymers of different redox potentials'. Bioelectrochemistry, 80 :38-42 [DOI] [Details]
(2009) 'Evaluation of performance and stability of biocatalytic redox films constructed with different copper oxygenases and osmium-based redox polymers'
Jenkins, PA,Boland, S,Kavanagh, P,Leech, D (2009) 'Evaluation of performance and stability of biocatalytic redox films constructed with different copper oxygenases and osmium-based redox polymers'. Bioelectrochemistry, 76 :162-168 [DOI] [Details]
(2009) 'Biocatalytic anode for glucose oxidation utilizing carbon nanotubes for direct electron transfer with glucose oxidase'
Vaze, A,Hussain, N,Tang, C,Leech, D,Rusling, J (2009) 'Biocatalytic anode for glucose oxidation utilizing carbon nanotubes for direct electron transfer with glucose oxidase'. Electrochemistry Communications, 11 :2004-2007 [DOI] [Details]
(2009) 'Enzyme-Amplified Amperometric Detection of DNA Using Redox Mediating Films on Gold Microelectrodes'
Hajdukiewicz, J,Boland, S,Kavanagh, P,Nowicka, A,Stojek, Z,Leech, D (2009) 'Enzyme-Amplified Amperometric Detection of DNA Using Redox Mediating Films on Gold Microelectrodes'. Electroanalysis, 21 :342-350 [DOI] [Details]
(2009) 'A stability comparison of redox-active layers produced by chemical coupling of an osmium redox complex to pre-functionalized gold and carbon electrodes'
Boland, S,Foster, K,Leech, D (2009) 'A stability comparison of redox-active layers produced by chemical coupling of an osmium redox complex to pre-functionalized gold and carbon electrodes'. Electrochimica Acta, 54 :1986-1991 [DOI] [Details]
(2008) 'Electroreduction of O-2 at a mediated Melanocarpus albomyces laccase cathode in a physiological buffer'
Kavanagh, P,Jenkins, P,Leech, D (2008) 'Electroreduction of O-2 at a mediated Melanocarpus albomyces laccase cathode in a physiological buffer'. Electrochemistry Communications, 10 :970-972 [DOI] [Details]
(2008) 'Designing stable redox-active surfaces: Chemical attachment of an osmium complex to glassy carbon electrodes prefunctionalized by electrochemical reduction of an in situ-generated aryldiazonium cation'
Boland, S,Barriere, F,Leech, D (2008) 'Designing stable redox-active surfaces: Chemical attachment of an osmium complex to glassy carbon electrodes prefunctionalized by electrochemical reduction of an in situ-generated aryldiazonium cation'. Langmuir, 24 :6351-6358 [DOI] [Details]
(2008) 'Improved stability of redox enzyme layers on glassy carbon electrodes via covalent grafting'
Pellissier, M,Barriere, F,Downard, AJ,Leech, D (2008) 'Improved stability of redox enzyme layers on glassy carbon electrodes via covalent grafting'. Electrochemistry Communications, 10 :835-838 [DOI] [Details]
(2008) 'Mediated enzyme electrodes for biological fuel cell and biosensor applications'
Boland,S., Kavanagh, P., Leech, D. (2008) 'Mediated enzyme electrodes for biological fuel cell and biosensor applications'. Ecs Transactions, 13 (21):77-87 [DOI] [Details]
(2007) 'Synthesis by radical cyclization and cytotoxicity of highly potent bioreductive alicyclic ring fused [1,2-a]benzimidazolequinones'
Lynch, M,Hehir, S,Kavanagh, P,Leech, D,O'Shaughnessy, J,Carty, MP,Aldabbagh, F (2007) 'Synthesis by radical cyclization and cytotoxicity of highly potent bioreductive alicyclic ring fused [1,2-a]benzimidazolequinones'. Chemistry-A European Journal, 13 :3218-3226 [DOI] [Details]
(2006) 'A laccase-glucose oxidase biofuel cell prototype operating in a physiological buffer'
Barriere, F,Kavanagh, P,Leech, D (2006) 'A laccase-glucose oxidase biofuel cell prototype operating in a physiological buffer'. Electrochimica Acta, 51 :5187-5192 [DOI] [Details]
(2006) 'Mobile voltammetric laboratory for ship-board and shore-based analyses of dissolved copper'
Knight,S., Morley, N., Leech, D., Cave, R. (2006) 'Mobile voltammetric laboratory for ship-board and shore-based analyses of dissolved copper'. Environmental Chemistry, 3 (6):450-456 [DOI] [Details]
(2005) 'Amperometric detection of catecholamine neurotransmitters using electrocatalytic substrate recycling at a laccase electrode'
Ferry, Y,Leech, D (2005) 'Amperometric detection of catecholamine neurotransmitters using electrocatalytic substrate recycling at a laccase electrode'. Electroanalysis, 17 :113-119 [Details]
(2004) 'Synthesis of benzimidazolequinone analogue of cyclopropamitosene antitumor agents'
John O'Shaughnessy, Desmond Cunningham, Paul Kavanagh, Dónal Leech, Patrick McArdle, Fawaz Aldabbagh (2004) 'Synthesis of benzimidazolequinone analogue of cyclopropamitosene antitumor agents'. Synlett, :2382-2384 [DOI] [Details]
(2004) 'Electron transfer mediator systems for bleaching of paper pulp'
Rochefort, D,Leech, D,Bourbonnais, R (2004) 'Electron transfer mediator systems for bleaching of paper pulp'. Green Chem, 6 :14-24 [DOI] [Details]
(2004) 'Targetting redox polymers as mediators for laccase oxygen reduction in a membrane-less biofuel cell'
Barriere, F,Ferry, Y,Rochefort, D,Leech, D (2004) 'Targetting redox polymers as mediators for laccase oxygen reduction in a membrane-less biofuel cell'. Electrochemistry Communications, 6 :237-241 [DOI] [Details]
(2004) 'Improved synthesis of 4,4 '-diamino-2,2 '-bipyridine from 4,4 '-dinitro-2,2 '-bipyridine-N,N '-dioxide'
Kavanagh, P,Leech, D (2004) 'Improved synthesis of 4,4 '-diamino-2,2 '-bipyridine from 4,4 '-dinitro-2,2 '-bipyridine-N,N '-dioxide'. Tetrahedron Letters, 45 :121-123 [DOI] [Details]
(2003) 'A voltammetric assay of antioxidants and inhibitors of soybean lipoxygenase'
Perusse, P,Leech, D (2003) 'A voltammetric assay of antioxidants and inhibitors of soybean lipoxygenase'. Electroanalysis, 15 :573-578 [Details]
(2002) 'Oxidation of lignin model compounds by organic and transition metal-based electron transfer mediators'
Rochefort, D,Bourbonnais, R,Leech, D,Paice, MG (2002) 'Oxidation of lignin model compounds by organic and transition metal-based electron transfer mediators'. Chemical Communications, :1182-1183 [DOI] [Details]
(2002) 'Electrochemical oxidation of transition metal-based mediators for pulp delignification'
Rochefort, D,Bourbonnais, R,Leech, D,Renaud, S,Paice, M (2002) 'Electrochemical oxidation of transition metal-based mediators for pulp delignification'. Journal Of The Electrochemical Society, 149 :15-20 [DOI] [Details]
(2002) 'Electrochemical determination of electroinactive guests of beta-cyclodextrin at a self-assembled monolayer interface'
Ju, HX,Dai, Z,Leech, D (2002) 'Electrochemical determination of electroinactive guests of beta-cyclodextrin at a self-assembled monolayer interface'. Science In China Series B-Chemistry, 45 :46-53 [Details]
(2002) 'Characterisation of an antibody coated microcantilever as a potential immuno-based biosensor'
Grogan, C,Raiteri, R,O'Connor, GM,Glynn, TJ,Cunningham, V,Kane, M,Charlton, M,Leech, D (2002) 'Characterisation of an antibody coated microcantilever as a potential immuno-based biosensor'. Biosensors & Bioelectronics, 17 :201-207 [DOI] [Details]
(2000) 'Biosensor warning devices: Reagentless detection of modulators of laccase activity'
Leech, D,Feerick, KO (2000) 'Biosensor warning devices: Reagentless detection of modulators of laccase activity'. Electroanalysis, 12 :1339-1342 [Details]
(2000) 'Transition metal complexes: A new class of laccase mediators for pulp bleaching'
Bourbonnais,R.,Rochefort, D.,Paice, M.G., Renaud, S.,Leech, D. (2000) 'Transition metal complexes: A new class of laccase mediators for pulp bleaching'. TAPPI Journal, 83 (10) [Details]
(2000) 'Dual electrode cyclic voltammetry under computer control using graphical programming of a bipotentiostat'
Perusse,P., Leech, D. (2000) 'Dual electrode cyclic voltammetry under computer control using graphical programming of a bipotentiostat'. Instrumentation Science and Technology, 28 (1) [Details]
(1999) 'Electrocatalytic oxidation and trace determination of catecholamine neurotransmitters at osmium complex polymer and Nafion dual-layer membrane carbon-base electrode'
Ni, JA,Ju, HX,Chen, HY,Leech, D (1999) 'Electrocatalytic oxidation and trace determination of catecholamine neurotransmitters at osmium complex polymer and Nafion dual-layer membrane carbon-base electrode'. Chemical Journal Of Chinese Universities-Chinese, 20 :224-226 [Details]
(1999) 'Adsorption and Desorption of Electroactive Self-Assembled Thiolate Monolayers on Gold'
Voicu, R., Ellis, T.J., Ju, H-X., Leech,D. (1999) 'Adsorption and Desorption of Electroactive Self-Assembled Thiolate Monolayers on Gold'. LANGMUIR, * (15):8170-8177 [Details]
(1999) 'Effect of electrolytes on the electrochemical behaviour of 11- (ferrocenylcarbonyloxy)undecanethiol SAMs on gold disk electrodes'
Ju, H., Leech, D. (1999) 'Effect of electrolytes on the electrochemical behaviour of 11- (ferrocenylcarbonyloxy)undecanethiol SAMs on gold disk electrodes'. Physical Chemistry Chemical Physics, 1 (7) [Details]
(1998) 'Laccase/mediator bleaching of kraft pulps: Identification of mediator active species and their role in oxidation of residual lignin subunits'
Bourbonnais,R.,Paice, Michael G., Leech, D.,Rochefort, D. (1998) 'Laccase/mediator bleaching of kraft pulps: Identification of mediator active species and their role in oxidation of residual lignin subunits'. Proceedings of the International Conference on Biotechnology in the Pulp and Paper Industry, 1 [Details]
(1998) 'Electrochemical analysis of the interactions of laccase mediators with lignin model compounds'
Bourbonnais,R., Leech, D., Paice, M.G. (1998) 'Electrochemical analysis of the interactions of laccase mediators with lignin model compounds'. Biochimica et Biophysica Acta - General Subjects, 1379 (3) [Details]
(1998) '[Os(bpy)(2)(PVP)(10)Cl]Cl polymer and Nafion dual-film modified graphite electrode for the amperometric determination of trace amounts of norepinephrine'
Ni, JA,Ju, HX,Chen, HY,Leech, D (1998) '[Os(bpy)(2)(PVP)(10)Cl]Cl polymer and Nafion dual-film modified graphite electrode for the amperometric determination of trace amounts of norepinephrine'. Analyst, 123 :2895-2898 [Details]
(1998) 'Host-guest interaction at a self-assembled monolayer/solution interface: An electrochemical analysis of the inclusion of 11-(ferrocenylcarbonyloxy)undecanethiol by cyclodextrins'
Ju, HX,Leech, D (1998) 'Host-guest interaction at a self-assembled monolayer/solution interface: An electrochemical analysis of the inclusion of 11-(ferrocenylcarbonyloxy)undecanethiol by cyclodextrins'. Langmuir, 14 :300-306 [Details]
(1997) 'Reagentless Mediated Laccase Electrode for the Detection of Enzyme Modulators'
Trudeau, F., Daigle, F., Leech, D. (1997) 'Reagentless Mediated Laccase Electrode for the Detection of Enzyme Modulators'. Analytical Chemistry, 69 (5) [Details]
(1997) 'Electrochemistry of poly(vinylferrocene) formed by direct electrochemical reduction at a glassy carbon electrode'
Ju, H., Leech, D. (1997) 'Electrochemistry of poly(vinylferrocene) formed by direct electrochemical reduction at a glassy carbon electrode'. Journal of the Chemical Society - Faraday Transactions, 93 (7) [Details]
(1997) 'Os(bpy)2(PVI)10Cl]Cl polymer-modified carbon fiber electrodes for the electrocatalytic oxidation of NADH'
Ju, H., Leech, D. (1997) 'Os(bpy)2(PVI)10Cl]Cl polymer-modified carbon fiber electrodes for the electrocatalytic oxidation of NADH'. Analytica Chimica Acta, 345 (1-3) [Details]
(1997) 'Reagentless Tyrosinase Enzyme Electrodes: Effects of Enzyme Loading, Electrolyte pH, Ionic Strength, and Temperature'
Daigle, F., Leech, D. (1997) 'Reagentless Tyrosinase Enzyme Electrodes: Effects of Enzyme Loading, Electrolyte pH, Ionic Strength, and Temperature'. Analytical Chemistry, 69 (20) [Details]
(1996) 'Oxidative detection of nitrite at an electrocatalytic [Ru(bipy)2poly-(4-vinylpyridine)10Cl]Cl electrochemical sensor applied for the flow injection determination of nitrate using a Cu/Cd redactor column'
Doherty,A.P., Stanley, M.A., Leech, D., Vos, J.G. (1996) 'Oxidative detection of nitrite at an electrocatalytic [Ru(bipy)2poly-(4-vinylpyridine)10Cl]Cl electrochemical sensor applied for the flow injection determination of nitrate using a Cu/Cd redactor column'. Analytica Chimica Acta, 319 (1-2) [Details]
(1996) 'Reagentless inhibition enzyme electrodes'
Trudeau, F., Daigle, F., Leech, D. (1996) 'Reagentless inhibition enzyme electrodes'. Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, 2 [Details]
(1996) 'High-performance liquid chromatographic determination of phenols using a tyrosinase-based amperometric biosensor detection system'
Adeyoju,O., Iwuoha, E.I., Smyth, M.R., Leech, D. (1996) 'High-performance liquid chromatographic determination of phenols using a tyrosinase-based amperometric biosensor detection system'. Analyst, 121 (12) [Details]
(1994) 'Affinity biosensors'
Leech,D. (1994) 'Affinity biosensors'. Chemical Society Reviews, 23 (3) [Details]
(1993) 'Biomagnetic neurosensors'
Leech,D., Rechnitz, C.A. (1993) 'Biomagnetic neurosensors'. Analytical Chemistry, 65 (22) [Details]
(1993) 'Crayfish walking leg neuronal biosensor for the detection of pyrazinamide and selected local anesthetics'
Leech,D., Rechnitz, G.A. (1993) 'Crayfish walking leg neuronal biosensor for the detection of pyrazinamide and selected local anesthetics'. Analytica Chimica Acta, 274 (1) [Details]
(1992) 'Determination of nitrite based on mediated oxidation at a carbon paste electrode modified with a ruthenium polymer'
O'Shea, T.J.,Leech, D.,Smyth, M.R., Vos, J.G. (1992) 'Determination of nitrite based on mediated oxidation at a carbon paste electrode modified with a ruthenium polymer'. Talanta, 39 (4) [Details]
(1992) 'Analysis of inorganic solids by laser ablation inductively coupled plasma spectrometry'
Franks, J., Harris, S.J., McKervey, M.A., Bahari, M.S., Criddle, W.J., Thomas, J.D.R., Kane, M., Dean, J.R., Hitchen, S.M., Dowle, C.J., Tranter, R.L., Marshall, J., Brown, I., Garden, L., Leech, D., Wang, J., Smyth,M.R., Arrigan, D.W.M., Svehla, G. (1992) 'Analysis of inorganic solids by laser ablation inductively coupled plasma spectrometry'. Analytical Proceedings, 29 (1) [Details]
(1991) 'Effect of composition of polymer backbone on spectroscopic and electrochemical properties of ruthenium(ii) bis(2,2?-bipyridyl)-containing 4-vinylpyridine/styrene copolymers'
Leech D., Forster R.J., Smyth M.R., Vos J.G. (1991) 'Effect of composition of polymer backbone on spectroscopic and electrochemical properties of ruthenium(ii) bis(2,2?-bipyridyl)-containing 4-vinylpyridine/styrene copolymers'. Journal of Materials Chemistry, 1 (4) [Details]
(1991) 'One-step fabrication of glucose sensors based on entrapment of glucose oxidase within poly(ester-sulfonic acid) coatings'
Wang, J.,Leech, D.,Ozsoz, M.,Martinez, S.,Smyth, M.R. (1991) 'One-step fabrication of glucose sensors based on entrapment of glucose oxidase within poly(ester-sulfonic acid) coatings'. Analytica Chimica Acta, 245 (2) [Details]
(1990) 'Electrocatalytic detection of streptomycin and related antibiotics at ruthenium dioxide modified graphite - Epoxy composite electrodes'
Leech D., Wang J., Smyth M.R. (1990) 'Electrocatalytic detection of streptomycin and related antibiotics at ruthenium dioxide modified graphite - Epoxy composite electrodes'. Analyst, 115 (11):1447-1450 [DOI] [Details]

Professional Associations

  Association Function From / To
Royal Society of Chemistry Fellow and Chair of the executive of Republic of Ireland section of the Analytical Division /
Insitute of Chemistry of Ireland Fellow /
Electrochemical Society Member /
Bioelectrochemical Society Member /
International Society of Electrochemistry Member /
International Society of Microbial Electrochemical Technology Member /

Committees

  Committee Function From / To
Galway branch of the Irish Federation of University Teachers Member of Executive 01-JAN-01 / 01-MAY-12
Executive Committee, Analytical Division, Royal Society of Chemistry Republic of Ireland Section Chair /

Employment

  Employer Position From / To
University of Hawaii, USA Post-Doctoral Researcher in Bioanalytical Chemistry 01-AUG-91 / 31-JUL-93
Université de Montréal, Canada Assistant Professor in Analytical Chemistry 01-AUG-93 / 01-SEP-97
National University of Ireland, Galway Professor in Chemistry 01-SEP-97 / 30-DEC-99

Languages

  Language
Gaeilge
French

Recent Postgraduate Students

  Graduation Name Degree Primary Supervisor
2016 Rakesh Kumar PhD Y
2015 Partha Jana PhD Y
2016 Isioma Osadebe PhD Y
2013 Peter Connolly (O Conghaile) PhD Y
2013 Domhnall MacAodha PhD Y
2012 Joanna Scott (nee Hajdukiewicz) PhD Y
2012 Saravanan Rengaraj PhD Y
2011 Peter Jenkins PhD Y
2010 Vincent Bonifay PhD Y
2008 Susan Boland PhD Y
2007 Sarah Knight PhD
2007 Gayle Kealy PhD Y
2006 Paul Kavanagh PhD Y
2006 Keith Feerick Msc Y
2003 Yvonne Slattery (nee Ferry) PhD Y
2003 Alan Sheridan Msc Y
2002 Dominic Rochefort PhD Y
2002 Eric Villard Msc Y
2001 Marjaneh Sarir Msc Y
1999 Pascal Perusse Msc Y
1997 Francis Daigle Msc Y
1997 Francis Daigle Msc Y
1996 Francis Trudeau Msc Y

Current Postgraduate Students (Research)

  Student Degree Type Type
Ali Ekhtiari Doctorate - Structured PhD (Science) Supervisor
Conan Mercer Doctorate - Structured PhD (Science) Supervisor
Richard Bennett Doctorate - Structured PhD (Science) Supervisor