Dr Manus Biggs

Ph.D

 
researcher
 

Biography

Peer Reviewed Journals

  Year Publication
(2018) 'Fractal form PEDOT/Au assemblies as thin-film neural interface materials'
Katarzyna Krukiewicz, Magdalena Chudy, Catalina Vallejo-Giraldo, Małgorzata Skorupa, Daria Więcławska, Manus Biggs (2018) 'Fractal form PEDOT/Au assemblies as thin-film neural interface materials'. Biomedical Materials, 13 [DOI] [ARAN Link] [Details]
(2019) 'Electrodeposited poly(3,4-ethylenedioxypyrrole) films as neural interfaces: cytocompatibility and electrochemical studies'
Katarzyna Krukiewicz, Agnieszka Kowalik, Dominika Czerwinska-Glowka, Manus J.P. Biggs (2019) 'Electrodeposited poly(3,4-ethylenedioxypyrrole) films as neural interfaces: cytocompatibility and electrochemical studies'. Electrochimica Acta, 302 :21-30 [DOI] [Details]
(2019) 'Electrodeposited poly(3,4-ethylenedioxypyrrole) films as neural interfaces: cytocompatibility and electrochemical studies'
Katarzyna Krukiewicz, Agnieszka Kowalik, Dominika Czerwińska-Główka, Manus J.P. Biggs (2019) 'Electrodeposited poly(3,4-ethylenedioxypyrrole) films as neural interfaces: cytocompatibility and electrochemical studies'. Electrochimica Acta, [DOI] [ARAN Link] [Details]
(2018) 'Chirality-Sorted Carbon Nanotube Films as High Capacity Electrode Materials'
Krukiewicz K, Maciej Krzywiecki, Biggs MJ, Janas D. (2018) 'Chirality-Sorted Carbon Nanotube Films as High Capacity Electrode Materials'. Rsc Advances, 8 (53):30600-30609 [DOI] [ARAN Link] [Details]
(2017) 'In Vitro Enzymatic Degradation of Tissue Grafts and Collagen Biomaterials by Matrix Metalloproteinases: Improving the Collagenase Assay'
Helling, AL,Tsekoura, EK,Biggs, M,Bayon, Y,Pandit, A,Zeugolis, DI (2017) 'In Vitro Enzymatic Degradation of Tissue Grafts and Collagen Biomaterials by Matrix Metalloproteinases: Improving the Collagenase Assay'. ACS Biomaterials Science & Engineering, 3 :1922-1932 [DOI] [Details]
(2018) 'Stable tissue-mimicking materials and an anatomically realistic, adjustable head phantom for electrical impedance tomography'
McDermott, B;McGinley, B;Krukiewicz, K;Divilly, B;Jones, M;Biggs, M;O'Halloran, M;Porter, E (2018) 'Stable tissue-mimicking materials and an anatomically realistic, adjustable head phantom for electrical impedance tomography'. Biomedical Physics & Engineering Express, 4 [DOI] [ARAN Link] [Details]
(2018) 'Stable tissue-mimicking materials and an anatomically realistic, adjustable head phantom for electrical impedance tomography'
McDermott, B,McGinley, B,Krukiewicz, K,Divilly, B,Jones, M,Biggs, M,O'Halloran, M,Porter, E (2018) 'Stable tissue-mimicking materials and an anatomically realistic, adjustable head phantom for electrical impedance tomography'. Biomedical Physics & Engineering Express, 4 [DOI] [Details]
(2015) 'Sensing the Difference: The Influence of Anisotropic Surfaces on Cell Behavior'
Ballester-Beltrán J, Biggs M, Dalby MJ, Salmeron-Sanchez M, and Leal-Egaña A. (2015) 'Sensing the Difference: The Influence of Anisotropic Surfaces on Cell Behavior'. Frontiers In Bioscience, 2 (39) [DOI] [Details]
(2015) 'An academic, clinical and industrial update on electro-spun, additive manufactured and imprinted medical devices'
Ryan CNM, Fuller KP, Larrañaga A, Biggs M, Bayon Y, Sarasua JR, Pandit A, Zeugolis D. (2015) 'An academic, clinical and industrial update on electro-spun, additive manufactured and imprinted medical devices'. Expert Review Of Medical Devices, [Details]
(2015) 'Substrate topography: A valuable in vitro tool, but a clinical red herring for in vivo tenogenesis'
English A, Azeem A, Biggs M, Jones E, Tripathi B, Basu N, Rooney N, Riley G, O'Riordan A, Cross G, Hutmacher D, Pandit A, Zeugolis DI, (2015) 'Substrate topography: A valuable in vitro tool, but a clinical red herring for in vivo tenogenesis'. Acta Biomaterialia, [Details]
(2015) 'The influence of anisotropic nano- to micro-topography on in vitro and in vivo osteogenesis'
Azeem, A,English, A,Kumar, P,Satyam, A,Biggs, M,Jones, E,Tripathi, B,Basu, N,Henkel, J,Vaquette, C,Rooney, N,Riley, G,O'Riordan, A,Cross, G,Ivanovski, S,Hutmacher, D,Pandit, A,Zeugolis, D (2015) 'The influence of anisotropic nano- to micro-topography on in vitro and in vivo osteogenesis'. Nanomedicine, 10 :693-711 [DOI] [Details]
(2015) 'Nanoscale neuroelectrode modification through self-assembly of block copolymers'
Mokarian-Tabari P, Vallejo-Giraldo C, Fernandez-Yague M, Cummins C, Morris MA, Biggs M.J. (2015) 'Nanoscale neuroelectrode modification through self-assembly of block copolymers'. Journal Of Materials Science: Materials In Medicine, 26 (120):1-5 [Details]
(2015) 'The influence of anisotropic nano- to micro-topography on in vitro and in vivo osteogenesis'
Azeem A, English E, Biggs M, Jones E, Tripathi B, Henkel J, Vaquette C, Rooney N, Riley G, O’Riordan A, Cross G, Hutmacher D, Pandit A, Zeugolis D (2015) 'The influence of anisotropic nano- to micro-topography on in vitro and in vivo osteogenesis'. Nanomedicine (London, England), 10 (5):693-711 [Details]
(2015) 'Special Focus on Nanoscale Regeneration'
Dalby MJ, Biggs MJ (2015) 'Special Focus on Nanoscale Regeneration'. Nanomedicine (London, England), 10 (5):677-680 [Details]
(2014) 'Biofunctionalisation of electrically conducting polymers'
Vallejo-Giraldo C, Kelly A, Biggs MJ (2014) 'Biofunctionalisation of electrically conducting polymers'. Drug Discovery Today, [Details]
(2014) 'Osteogenic Lineage Restriction by Osteoprogenitors Cultured on Nanometric Grooved Surfaces – the Role of Focal Adhesion Maturation'
Cassidy JW, Roberts JN, Smith C, Robertson M, White K, Biggs MJ, Oreffo RO, Dalby MJ (2014) 'Osteogenic Lineage Restriction by Osteoprogenitors Cultured on Nanometric Grooved Surfaces – the Role of Focal Adhesion Maturation'. Acta Biomateriala, [Details]
(2014) 'Cellular response to ferroelectric PVDF-TrFE surfaces of varying polymer concentration'
Biggs MJ, Parisi-Capdevila E, Valejo-Giraldo C, Wind SJ (2014) 'Cellular response to ferroelectric PVDF-TrFE surfaces of varying polymer concentration'. Journal Of Biomedical Nanotechnology, [Details]
(2014) 'Biomimetic Approaches in Bone Tissue Engineering: Integrating Biological and Physicomechanical Strategies'
Fernandez-Yague MA, Abbah SA, McNamara L, Zeugolis DI, Pandit A, * Biggs MJ (2014) 'Biomimetic Approaches in Bone Tissue Engineering: Integrating Biological and Physicomechanical Strategies'. Advanced Drug Delivery Reviews, [DOI] [Details]
(2014) 'An insight into morphometric descriptors of cell shape that pertain to regenerative medicine'
Lobo J, See E, Biggs MJ, Pandit A. (2014) 'An insight into morphometric descriptors of cell shape that pertain to regenerative medicine'. Journal Of Tissue Engineering And Regenerative Medicine, [DOI] [Details]
(2014) 'The past, present and future in scaffold-based tendon treatments'
Lomas, A. J. Ryan, C. N. Sorushanova, A. Shologu, N. Sideri, A. I. Tsioli, V. Fthenakis, G. C. Tzora, A. Skoufos, I. Quinlan, L. R. O'Laighin, G. Mullen, A. M. Kelly, J. L. Kearns, S. Biggs, M. Pandit, A. Zeugolis, D. I. (2014) 'The past, present and future in scaffold-based tendon treatments'. Advanced Drug Delivery Reviews, [Details]
(2014) 'Diatoms: A Biotemplating Approach to Fabricating Drug Delivery Reservoirs'
Chao J, Biggs MJ, Pandit A. (2014) 'Diatoms: A Biotemplating Approach to Fabricating Drug Delivery Reservoirs'. Expert Opinion On Drug Delivery, 11 (11):1687-1695 [Details]
(2012) 'The role of microtopography in cellular mechanotransduction'
McNamara LE, Burchmore R, Riehle MO, Herzyk P, Tsimbouri PM, Biggs MJP, Wilkinson CDW, Curtis ASG, Dalby MJ. (2012) 'The role of microtopography in cellular mechanotransduction'. Biomaterials, [Details]
(2011) 'High resolution imaging of the immunological synapse and TCR microclustering through micro fabricated substrates’'
Biggs MJ, Gondarenko A, Milone MC, Santos L, Wind SJ (2011) 'High resolution imaging of the immunological synapse and TCR microclustering through micro fabricated substrates’'. Journal Of The Royal Society Interface, [Details]
(2010) 'Focal adhesions in osteoneogenesis'
Biggs MJ, Dalby MJ (2010) 'Focal adhesions in osteoneogenesis'. Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, [Details]
(2010) 'Nanotopographical modification: a regulator of cellular function through focal adhesions'
Biggs MJ, Dalby MJ. (2010) 'Nanotopographical modification: a regulator of cellular function through focal adhesions'. Nanomedicine: Nanotechnology, Biology, And Medicine, [Details]
(2010) 'Nanotopographical control of stem cell differentiation'
McNamara L, McMurray RJ, Biggs MJ, Kantawong F, Oreffo ROC, Dalby MJ (2010) 'Nanotopographical control of stem cell differentiation'. Tissue Engineering, [Details]
(2009) 'The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+ enriched skeletal stem cells'
Biggs MJ, Richards RG, Gadegaard N, Wilkinson CD, Oreffo RO, Dalby MJ. (2009) 'The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+ enriched skeletal stem cells'. Biomaterials, [Details]
(2009) 'Interactions with nanoscale topography: Adhesion quantification and signal transduction in cells of osteogenic and multipotent lineage'
Biggs MJ, Richards RG, Gadegaard N, McMurray RJ, Affrossman S, Wilkinson CD, Oreffo RO, Dalby MJ. (2009) 'Interactions with nanoscale topography: Adhesion quantification and signal transduction in cells of osteogenic and multipotent lineage'. J. Biomedical Materials Research- Part A, [Details]
(2008) 'Focal adhesion interactions with nanostructures: A novel method for immuno-SEM labelling of focal adhesions in S-phase cells'
Biggs MJ, Richards RG, Wilkinson CD, Dalby MJ. (2008) 'Focal adhesion interactions with nanostructures: A novel method for immuno-SEM labelling of focal adhesions in S-phase cells'. Journal Of Microscopy-Oxford, [Details]
(2008) 'Adhesion formation of primary human osteoblasts and the functional response of mesenchymal stem cells to 330 nm deep microgrooves'
Biggs MJ, Richards RG, Gadegaard N, Wilkinson CD, Oreffo ROC, Affrossman S, Dalby MJ. (2008) 'Adhesion formation of primary human osteoblasts and the functional response of mesenchymal stem cells to 330 nm deep microgrooves'. Journal Of The Royal Society Interface, [Details]
(2007) 'The effects of nanoscale pits on primary human osteoblast adhesion formation and cellular spreading'
Biggs MJ, Richards RG, Gadegaard N, Wilkinson CD, Dalby MJ (2007) 'The effects of nanoscale pits on primary human osteoblast adhesion formation and cellular spreading'. Journal Of Material Science: Materials In Medicine, [Details]
(2006) 'Nanotopographical stimulation of mechanotransduction and changes in interphase centromere positioning'
Dalby MJ, Biggs MJ, Gadegaard N, Kalna G, Wilkinson CD, Curtis AS (2006) 'Nanotopographical stimulation of mechanotransduction and changes in interphase centromere positioning'. Journal Of Cellular Biochemistry, [Details]
(2006) 'Regulation of implant surface cell adhesion: characterization and quantification of S-phase primary osteoblast adhesions on biomimetic nanoscale substrates'
Biggs MJ, Richards RG, Gadegaard N, Wilkinson CD, Dalby MJ (2006) 'Regulation of implant surface cell adhesion: characterization and quantification of S-phase primary osteoblast adhesions on biomimetic nanoscale substrates'. Journal Of Orthopaedic Research, [Details]

Book Chapters

  Year Publication
(2018) 'Cell Carriers for Bone and Cartilage Repair In Vivo'
Thomas, D., Biggs, M., O’Brien, T. and Pandit, A. (2018) 'Cell Carriers for Bone and Cartilage Repair In Vivo' In: Biomaterials for Cell Delivery: Vehicles in Regenerative Medicine. London: CRC/Press Taylor & Francis Group. [DOI] [Details]
(2015) 'On the use of stereology in tissue scaffolds'
Dockery, P & Biggs, M. (2015) 'On the use of stereology in tissue scaffolds' In: Characterisation and design of Tissue Scaffolds. UK: Wiley. [Details]
(2015) 'Tendon regeneration: Understanding tissue physiology and development to engineer functional substitutes'
Lomas, A., English, A., Biggs, M., Pandit, A., Zeugolis, D.I. (2015) 'Tendon regeneration: Understanding tissue physiology and development to engineer functional substitutes' In: Engineering anisotropic 2D and 3D structures for tendon repair and regeneration. UK: Elsevier Science. [Details]
(2013) 'The Modulation of Skeletal Stem Cell Function Through Nanoscale Topography'
Biggs MJ, McNamara L. (2013) 'The Modulation of Skeletal Stem Cell Function Through Nanoscale Topography' In: Stem Cells & Bone Tissue. Boca Raton, FL: CRC Press. [Details]
(2012) 'Cellular response to nanoscale features'
Biggs MJ, Dalby MJ, Wind SJ (2012) 'Cellular response to nanoscale features' In: The Nanobiotechnology Handbook. Boca Raton, FL: CRC Press. [Details]
(2011) 'Using immuno-scanning electron microscopy for simultaneous observation of cell adhesion interaction at the nano/microscale in S-phase cells'
Biggs MJ, Richards RG, Dalby (2011) 'Using immuno-scanning electron microscopy for simultaneous observation of cell adhesion interaction at the nano/microscale in S-phase cells' In: Methods in Molecular Biology 3D Cell Culture. New York, NY 10013-1578: Humana Press. [Details]

Conference Publications

  Year Publication
(2016) 10th World Biomaterials Congress
Vallejo-Giraldo, C., Dowd, E., Papy-Garcia, D., Pandit, A. and Biggs, M.J. (2016) Functionalized PEDOT Polymeric Coatings for Neuroelectrodes: Topographical and Biological Strategies 10th World Biomaterials Congress [Details]
(2016) Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland
Ryan, C.N.M., Biggs, M.J., Pandit, A. and Zeugolis, D.I. (2016) Multifactorial Approaches for Cell Phenotype Maintenance and Function Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland [Details]
(2016) Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland
Vallejo-Giraldo, C., Dowd, E., Papy-Garcia, D., Pandit, A. and Biggs, M.J.P. (2016) PEDOT Polymeric Coatings for Neuroelectrodes: Topographical and Biologic Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland [Details]
(2016) 10th World Biomaterials Congress
Fernandez-Yague, M.A., Zeugolis, D., Pandit, A. and Biggs, M.J. (2016) Piezoelectric Nanoscaffolds: Mediating Tendon Regeneration through Activation of Piezoresponsive Receptors 10th World Biomaterials Congress [Details]
(2016) Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland
Rahman, A.A., Tofail, S.A.M., Lukasz, B., Rodriguez, B.J., Biggs, M.J. and Pandit, A. (2016) Modification of Living Diatom, Thalassiosira weissflogii by Calcium Precursor as a Sacrificial Template for Development of Artificial Antigen Presenting Cell Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland [Details]
(2016) 10th World Biomaterials Congress
Biggs, M., Mokarian-Tabari, P., Vallejo-Giraldo, C., Thomas, D., Morris, M.A. and Pandit, A. (2016) Nanopillar Modified Neuroelectrodes through Block Copolymer Self-Assembly 10th World Biomaterials Congress [Details]
(2016) 10th World Biomaterials Congress
Pugliese, E., Larranaga, A., Fernandez-Yague, M., Vallejo Giraldo, C., Tadajon, G., Pandit, A. and Biggs, M.J. (2016) Investigating a Novel Polyhydroxyalkanoate/Multiwall Carbon Nanotubes Nanocomposite as an Electrically Conducting Implant Coating for Neuroprosthetic Devices 10th World Biomaterials Congress [Details]
(2016) Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland
Fernandez-Yague, M.A., Zeugolis, D., Pandit, A. and Biggs, M.J.P. (2016) Piezoelectric Nanoscaffolds: Mediating Tendon Regeneration through Activation of Piezoresponsive Receptors Bioengineering in Ireland 2016, the Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland [Details]
(2016) 10th World Biomaterials Congress
Delgado, L., Fuller, K., Fernandez-Yague, M.A., Biggs, M., Pandit, A. and Zeugolis, D.I. (2016) Collagen Cross-Linking Increases Scaffold Stability while Modulates Pro-Inflammatory Macrophage Response 10th World Biomaterials Congress [Details]
(2016) Tissue Engineering and Regenerative Medicine International Society (TERMIS) – EU Meeting
Ryan, C., Biggs, M.J., Pandit, A. and Zeugolis, D.I. (2016) Multifactorial Approaches for Cell Phenotype Maintenance and Function Tissue Engineering and Regenerative Medicine International Society (TERMIS) – EU Meeting [Details]
(2014) TISSUE ENGINEERING AND REGENERATIVE MEDICINE
MJP Biggs, C Vallejo-giraldo, A Pandit (2014) Morphological modification of conducting polymers TISSUE ENGINEERING AND REGENERATIVE MEDICINE [Details]
(2012) AMERICAN SOCIETY FOR CELL BIOLOGY Meeting
LC Santos, M Biggs, S Wind, M Dustin, M Sheetz (2012) Rigidity Sensing in T cells by Actin-Dependent Phosphorylation of Src Family Kinase Substrate Cas-L AMERICAN SOCIETY FOR CELL BIOLOGY Meeting [Details]
(2007) Comparative Biochemistry and Physiology, Part A
M Biggs, M Dalby, C Wilkinson, N Gadegaard, G Richards (2007) The influence of nanoscale structures on osteoblast adhesion Comparative Biochemistry and Physiology, Part A [Details]

Conference Poster

  Year Publication
(2005) Cholecyst Derived Extracellular Matrix, a Potential Scaffold. 19th European Conference on Biomaterials.
Anilkumar, T., Biggs, M., and Pandit A (2005) Cholecyst Derived Extracellular Matrix, a Potential Scaffold. 19th European Conference on Biomaterials. Sorrento, Italy: Conference Poster [Details]

Editorial

  Year Publication
(2017) Biomimetic Bioactive Biomaterials: The Next Generation of Implantable Devices.
Tsiapalis, D,De Pieri, A,Biggs, M,Pandit, A,Zeugolis, DI (2017) Biomimetic Bioactive Biomaterials: The Next Generation of Implantable Devices. Editorial [DOI] [Details]
(2018) Foreword to special issue on two-dimensional biomaterials in regenerative medicine Editorial.
Biggs, M,Zeugolis, D,Pandit, A (2018) Foreword to special issue on two-dimensional biomaterials in regenerative medicine Editorial. Editorial [DOI] [Details]