Dr Aaron Liew

MB Bch BAO LRCP & SI, MRCPI, Ph.D

Contact Details

Senior Lecturer
Endocrinology
School of Medicine
CSI
NUI Galway

T: Ext. 2963
E: aaron.liew@nuigalway.ie
 
researcher

Biography

Research Interests

Peer Reviewed Journals

  Year Publication
(2016) 'Gene therapy for peripheral arterial disease (Protocol)'
Liew A, Bhattacharya V, Shaw J, Stansby G (2016) 'Gene therapy for peripheral arterial disease (Protocol)'. Cochrane Database Of Systematic Reviews, (1) [DOI] [Details]
(2015) 'De Novo Donor-Specific HLA Antibodies Are Associated With Rapid Loss of Graft Function Following Islet Transplantation in Type 1 Diabetes'
Brooks AM, Carter V, Liew A, Marshall H, Aldibbiat A, Sheerin NS, Manas DM, White SA, Shaw JA (2015) 'De Novo Donor-Specific HLA Antibodies Are Associated With Rapid Loss of Graft Function Following Islet Transplantation in Type 1 Diabetes'. American Journal Of Transplantation, 15 (12):3239-3246 [DOI] [Details]
(2015) 'Cell Therapy for Critical Limb Ischemia: A Meta-Analysis of Randomized Controlled Trials'
Liew A, Bhattacharya V, Shaw J, Stansby G (2015) 'Cell Therapy for Critical Limb Ischemia: A Meta-Analysis of Randomized Controlled Trials'. Angiology, [DOI] [Details]
(2014) 'The Potential of Cell-based Therapy for Diabetes and Diabetes-related Vascular Complications'
Liew, A,O'Brien, T (2014) 'The Potential of Cell-based Therapy for Diabetes and Diabetes-related Vascular Complications'. Current Diabetes Reports, 14 [DOI] [Details]
(2014) 'Mesenchymal Stromal Cell Therapy for Crohn's Disease'
Liew, A,O'Brien, T,Egan, L (2014) 'Mesenchymal Stromal Cell Therapy for Crohn's Disease'. Digestive Diseases, 32 :50-60 [DOI] [Details]
(2014) 'Extended-duration new oral anticoagulants for venous thromboprophylaxis in patients undergoing total hip arthroplasty: a meta-analysis of the randomized controlled trials'
Liew, A,Eikelboom, JW,O'Donnell, M (2014) 'Extended-duration new oral anticoagulants for venous thromboprophylaxis in patients undergoing total hip arthroplasty: a meta-analysis of the randomized controlled trials'. Journal Of Thrombosis And Haemostasis, 12 :107-109 [DOI] [Details]
(2014) 'Comparing mortality in patients with atrial fibrillation who are receiving a direct-acting oral anticoagulant or warfarin: a meta-analysis of randomized trials'
Liew, A,O'Donnell, M,Douketis, J (2014) 'Comparing mortality in patients with atrial fibrillation who are receiving a direct-acting oral anticoagulant or warfarin: a meta-analysis of randomized trials'. Journal Of Thrombosis And Haemostasis, 12 :1419-1424 [DOI] [Details]
(2013) 'Assessment of Anticoagulation Intensity and Management of Bleeding With Old and New Oral Anticoagulants'
Liew, A,Eikelboom, JW,O'Donnell, M,Hart, RG (2013) 'Assessment of Anticoagulation Intensity and Management of Bleeding With Old and New Oral Anticoagulants'. Canadian Journal Of Cardiology, 29 :34-44 [DOI] [Details]
(2013) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model'
O'Loughlin, A,Kulkarni, M,Vaughan, EE,Creane, M,Liew, A,Dockery, P,Pandit, A,O'Brien, T (2013) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model'. Stem Cell Research & Therapy, 4 [DOI] [Details]
(2013) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model'
O'Loughlin A, Kulkarni M, Vaughan EE, Creane M, Liew A, Dockery P, Pandit A, O'Brien T (2013) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model'. Stem Cell Research & Therapy, 4 (6) [DOI] [Details]
(2013) 'Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury'
Riegler, J,Liew, A,Hynes, SO,Ortega, D,O'Brien, T,Day, RM,Richards, T,Sharif, F,Pankhurst, QA,Lythgoe, MF (2013) 'Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury'. Biomaterials, 34 :1987-1994 [DOI] [Details]
(2013) 'Robust, Efficient, and Practical Electrogene Transfer Method for Human Mesenchymal Stem Cells Using Square Electric Pulses'
Liew, A,Andre, FM,Lesueur, LL,De Menorval, MA,O'Brien, T,Mir, LM (2013) 'Robust, Efficient, and Practical Electrogene Transfer Method for Human Mesenchymal Stem Cells Using Square Electric Pulses'. Human Gene Therapy Methods, 24 :289-297 [DOI] [Details]
(2012) 'Therapeutic potential for mesenchymal stem cell transplantation in critical limb ischemia'
Liew, A,O'Brien, T (2012) 'Therapeutic potential for mesenchymal stem cell transplantation in critical limb ischemia'. Stem Cell Research & Therapy, 3 [DOI] [Details]
(2012) 'Randomized controlled trials of new oral anticoagulants for stroke prevention in atrial fibrillation'
Liew, A,Eikelboom, JW,O'Donnell, M (2012) 'Randomized controlled trials of new oral anticoagulants for stroke prevention in atrial fibrillation'. Current Opinion In Cardiology, 27 :331-339 [DOI] [Details]
(2012) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhances wound healing in the alloxan-induced diabetic rabbit ear ulcer model'
O'Loughlin, A,Mangesh, M,Vaughan, EE,Creane, M,Liew, A,Dockery, P,Pandit, A,O'Brien, T (2012) 'Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhances wound healing in the alloxan-induced diabetic rabbit ear ulcer model'. Stem Cell Research & Therapy, :248-248 [Details]
(2012) 'Optimal Electrogene Transfer Method for Human Mesenchymal Stem Cells'
Liew, A,Andre, F,De Menorval, MA,O'Brien, T,Mir, L (2012) 'Optimal Electrogene Transfer Method for Human Mesenchymal Stem Cells'. Human Gene Therapy Methods, :242-243 [Details]
(2012) 'Pre-treatment of Endothelial Progenitor Cells with Osteopontin Enhances Cell Therapy for Peripheral Vascular Disease'
Vaughan, E; Liew, A; Mashayekhi, K; Dockery, P; McDermott, J; Kealy, B; Flynn, A; Duffy, A; Coleman, C.M.; O'Regan A; Barry, F; O'Brien, T. (2012) 'Pre-treatment of Endothelial Progenitor Cells with Osteopontin Enhances Cell Therapy for Peripheral Vascular Disease'. Cell Transplantation, 21 (6):1095-1107 [Details]
(2012) 'Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury'
Riegler J, Liew A, Hynes SO, Ortega D, O'Brien T, Day RM, Richards T, Sharif F, Pankhurst QA, Lythgoe MF. (2012) 'Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury'. Biomaterials, [Details]
(2012) 'Therapeutic potential for mesenchymal stem cell transplantation in critical limb ischemia'
Liew A, O’Brien T (2012) 'Therapeutic potential for mesenchymal stem cell transplantation in critical limb ischemia'. Stem Cell Res Ther, [Details]
(2012) 'Pretreatment of Endothelial Progenitor Cells With Osteopontin Enhances Cell Therapy for Peripheral Vascular Disease'
Vaughan, EE,Liew, A,Mashayekhi, K,Dockery, P,McDermott, J,Kealy, B,Flynn, A,Duffy, A,Coleman, C,O'Regan, A,Barry, FP,O'Brien, T (2012) 'Pretreatment of Endothelial Progenitor Cells With Osteopontin Enhances Cell Therapy for Peripheral Vascular Disease'. Cell Transplantation, 21 :1095-1107 [DOI] [Details]
(2011) 'Developing Cell-Specific Antibodies to Endothelial Progenitor Cells Using Avian Immune Phage Display Technology'
Bowes, T,Hanley, SA,Liew, A,Eglon, M,Mashayekhi, K,O'Kennedy, R,Barry, F,Taylor, WR,O'Brien, T,Griffin, MD,Finlay, WJJ,Greiser, U (2011) 'Developing Cell-Specific Antibodies to Endothelial Progenitor Cells Using Avian Immune Phage Display Technology'. Journal of biomolecular screening, 16 :744-754 [DOI] [Details]
(2009) 'Comparison of Viral and Nonviral Vectors for Gene Transfer to Human Endothelial Progenitor Cells'
Kealy, B,Liew, A,McMahon, JM,Ritter, T,O'Doherty, A,Hoare, M,Greiser, U,Vaughan, EE,Maenz, M,O'Shea, C,Barry, F,O'Brien, T (2009) 'Comparison of Viral and Nonviral Vectors for Gene Transfer to Human Endothelial Progenitor Cells'. Tissue Engineering Part C-Methods, 15 :223-231 [DOI] [Details]
(2008) 'Clinical insights into the safety and utility of the insulin tolerance test (ITT) in the assessment of the hypothalamo-pituitary-adrenal axis'
Finucane FM, Liew A, Thornton E, Rogers B, Tormey W, Agha A. (2008) 'Clinical insights into the safety and utility of the insulin tolerance test (ITT) in the assessment of the hypothalamo-pituitary-adrenal axis'. Clin Endocrinol (Oxf), 69 (4):603-607 [DOI] [Details]
(2006) 'Endothelial progenitor cells: diagnostic and therapeutic considerations'
Liew, A,Barry, F,O'Brien, T (2006) 'Endothelial progenitor cells: diagnostic and therapeutic considerations'. Bioessays, 28 :261-270 [DOI] [Details]
(2006) 'Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins'
Duffy A, Liew A, O'Sullivan J, Avalos G, Samali A, O'Brien T (2006) 'Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins'. Endothelium, 13 (1):9-16 [DOI] [Details]
(2006) 'The role of the combined diabetic nephropathy clinic'
McDermott, J., Liew, A., Dunne, F. & Lappin, D. (2006) 'The role of the combined diabetic nephropathy clinic'. DiabetesWise, [Details]
(2004) 'Conventional glucocorticoid replacement overtreats adult hypopituitary patients with partial ACTH deficiency'
Agha A, Liew A, Finucane F, Baker L, O'Kelly P, Tormey W, Thompson CJ. (2004) 'Conventional glucocorticoid replacement overtreats adult hypopituitary patients with partial ACTH deficiency'. Clin Endocrinol (Oxf), 60 (6):688-693 [DOI] [Details]

Book Chapters

  Year Publication
(2015) 'Chapter 5: Isolation of Endothelial Progenitor Cells (EPCs)'
Liew A, O'Brien T (2015) 'Chapter 5: Isolation of Endothelial Progenitor Cells (EPCs)' In: Handbook of Vascular Biology Techniques. Springer: Springer. [DOI] [Details]
(2012) 'Mesenchymal Stem Cells: Clinical Applications (An Overview)'
Liew A, O’Brien T. (2012) 'Mesenchymal Stem Cells: Clinical Applications (An Overview)' In: Stem Cells and Cancer Stem Cells, Volume 6. U.S.A: Springer. [Details]

Abstract

  Year Publication
(2012) Osteopontin Treated Circulating Angiogenic Cells Enhance Functional Recovery in a SCID Model of Hindlimb Ischemia.
Vaughan, EE,Chen, XZ,Creane, M,Nogues, CS,Liew, A,Duffy, A,O'Brien, T (2012) Osteopontin Treated Circulating Angiogenic Cells Enhance Functional Recovery in a SCID Model of Hindlimb Ischemia. Abstract [Details]
(2012) Intramuscular allogeneic mesenchymal stem cells are of comparable efficacy to syngeneic MSCs in hind limb ischaemia of diabetic animals.
Liew, A,Baustian, C,Thomas, D,Vaughan, E,Chen, X,Nogues, CS,Creane, M,Alagesan, S,Owens, P,Horan, J,Ceredig, R,Dockery, P,Griffin, M,Duffy, A,O'Brien, T (2012) Intramuscular allogeneic mesenchymal stem cells are of comparable efficacy to syngeneic MSCs in hind limb ischaemia of diabetic animals. Abstract [Details]
(2010) American Diabetes Association recommendation adherence among patients attending the adult diabetes clinic in Galway University Hospital.
Cahill, S,Liew, A,O'Brien, T (2010) American Diabetes Association recommendation adherence among patients attending the adult diabetes clinic in Galway University Hospital. Abstract [Details]
(2005) Distinct Effects of High Glucose Conditions on endothelial cells of macrovascular and microvascular origin. Irish Angiology Society, Fifth Annual Meeting, March 2005 and Irish Endocrinology Society.
Duffy A, Liew A, O' Sullivan J, Samali A, Avalos G, O' Brien T (2005) Distinct Effects of High Glucose Conditions on endothelial cells of macrovascular and microvascular origin. Irish Angiology Society, Fifth Annual Meeting, March 2005 and Irish Endocrinology Society. Abstract [Details]
(2005) Adenoviral-mediated antioxidant overexpression: possible protective role against hyperglycemic conditions in HAEC. American Society for Gene Therapy.
Duffy A, Liew A, Samali A, O' Brien T (2005) Adenoviral-mediated antioxidant overexpression: possible protective role against hyperglycemic conditions in HAEC. American Society for Gene Therapy. Abstract [Details]
(2005) EPC number and functions in patients with poorly controlled, uncomplicated Type 1 Diabetes Mellitus. Irish Endocrine Society 30th Annual Meeting.
Liew A, McDermott J, Kealy B, Gaffney M, Sharif F, DeLappe E, O'Brien T (2005) EPC number and functions in patients with poorly controlled, uncomplicated Type 1 Diabetes Mellitus. Irish Endocrine Society 30th Annual Meeting. Abstract [Details]
(2005) Temporo-profile of Stent Based Adenovirus Mediated Gene Therapy. Irish Journal of Medical Science.
Sharif, F, McMahon, J, Hynes, SO, Hynes, N, Liew, A, Crowley, J, O'Brien, T (2005) Temporo-profile of Stent Based Adenovirus Mediated Gene Therapy. Irish Journal of Medical Science. Abstract [Details]
(2005) SestMIBI Scanning in Hyperparathyroidism; the Galway Experience. Irish Endocrine Society.
Ali-Khan K, McDermott JH, Liew A, Grimes H, McCarthy P, Dunne F, Dinneen S OBrien T. (2005) SestMIBI Scanning in Hyperparathyroidism; the Galway Experience. Irish Endocrine Society. Abstract [Details]
(2006) Endothelial progenitor cells in Type 1 Diabetes: Declining in tandem with increasing cardiovascular risk?. Irish Endocrine Society 31st Annual Meeting.
McDermott JH, Liew A, Avalos G, O'Brien T (2006) Endothelial progenitor cells in Type 1 Diabetes: Declining in tandem with increasing cardiovascular risk?. Irish Endocrine Society 31st Annual Meeting. Abstract [Details]
(2006) Induction of therapeutic angiogenesis by endothelial progenitor cells. Irish Endocrine Society 31st Annual Meeting.
Liew A, McDermott J, Sharif F, Dockery P, Gaffney M, O'Brien T (2006) Induction of therapeutic angiogenesis by endothelial progenitor cells. Irish Endocrine Society 31st Annual Meeting. Abstract [Details]
(2007) Deleterious effect of hydrocortisone on endothelial progenitor cell number and function. Oral Presentation in Irish Endocrine Society 32nd Annual Meeting, Dublin, Ireland.
McDermott JH, Liew A, MacCarthy F, Sheahan J, Logie JJ, Hadoke PW, Walker BR, O'Brien T (2007) Deleterious effect of hydrocortisone on endothelial progenitor cell number and function. Oral Presentation in Irish Endocrine Society 32nd Annual Meeting, Dublin, Ireland. Abstract [Details]
(2008) The Role of Osteopontin in Angiogenesis. ISGCT Annual Conference.
Vaughan, Erin, Liew, A, Coleman C, O'Brien, T (2008) The Role of Osteopontin in Angiogenesis. ISGCT Annual Conference. Abstract [Details]
(2008) Critical Role for Osteopontin in Endothelial Progenitor Cell (EPC) Function. International Society for Cell Therapy in Miami, FL.
Liew A, Bowes T, Coleman C, Greiser U, O'Brien T (2008) Critical Role for Osteopontin in Endothelial Progenitor Cell (EPC) Function. International Society for Cell Therapy in Miami, FL. Abstract [Details]
(2008) Endothelial Progenitor Cell Dysfunction in Diabetes Mellitus: A Role for Osteopontin. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies, Hilton Head Island, South Carolina USA.
Liew A, Bowes T, Coleman CM, Greiser U, O'Brien T (2008) Endothelial Progenitor Cell Dysfunction in Diabetes Mellitus: A Role for Osteopontin. 12th Annual Hilton Head Workshop, Regenerative Medicine: Advancing to Next Generation Therapies, Hilton Head Island, South Carolina USA. Abstract [Details]
(2010) OPN exposure increases the angiogenic potential of endothelial progenitor cells. Irish Journal of Medical Science Poster 27.
Vaughan EE, O'Loughlin A, Liew A, Duffy A, O'Brien T (2010) OPN exposure increases the angiogenic potential of endothelial progenitor cells. Irish Journal of Medical Science Poster 27. Abstract [Details]
(2010) OPN exposure increases the angiogenic potential of endothelial progenitor cells. Irish Endocrine Society.
Vaughan EE, O'Loughlin A, Liew A, Duffy A, O'Brien T (2010) OPN exposure increases the angiogenic potential of endothelial progenitor cells. Irish Endocrine Society. Abstract [Details]
(2012) Short Term Safety of Human Bone Marrow Derived Mesenchymal Stem Cells in Immunodeficient Mice Following Intramuscular Delivery.
Creane, M,Alagesan, SK,Flavin, R,Hynes, S,Griffin, D,Thomas, D,Vaughan, E,Liew, A,Duffy, A,O'Brien, T (2012) Short Term Safety of Human Bone Marrow Derived Mesenchymal Stem Cells in Immunodeficient Mice Following Intramuscular Delivery. Abstract [Details]
(2013) Therapeutic Potential of Different Osteopontin Isoforms in Pulmonary and Vascular Diseases.
O'Toole, D,Liew, A,Gaffney, D,Pandit, A,O'Brien, T (2013) Therapeutic Potential of Different Osteopontin Isoforms in Pulmonary and Vascular Diseases. Abstract [Details]

Meeting

  Year Publication
(2007) Endothelial progenitor cell number: A novel concept in pathogenesis of increased cardiovascular risks in obstructive sleep apnoea syndrome.
Uzbeck, M,Liew, A,Mcdermott, J,Gallagher, D,Saleem, I,Avalos, G,Gilmartin, JJ,O'Brien, T (2007) Endothelial progenitor cell number: A novel concept in pathogenesis of increased cardiovascular risks in obstructive sleep apnoea syndrome. Meeting [Details]

Reviews

  Year Publication
(2008) Endothelial progenitor cells for the treatment of diabetic vasculopathy: panacea or Pandora's box?.
Liew, A,McDermott, JH,Barry, F,O'Brien, T (2008) Endothelial progenitor cells for the treatment of diabetic vasculopathy: panacea or Pandora's box?. Reviews [DOI] [Details]