Dr Beth Mallard

BSc, Ph.D

Contact Details

Lecturer Below The Bar
Physiology
School of Medicine
NUI Galway

E: BETH.MALLARD@nuigalway.ie
 
researcher

Biography

Beth Mallard received a BSC in Physiology in 2002 from the University of Otago in Dunedin, New Zealand. Following her undergraduate degree, she worked as a Research Assistant at Kings' College London/Guy's Hospital. She returned to New Zealand and was awarded a PhD from the University of Otago in 2011, studying "The role of Toll-like receptor 4 in Concanavalin A-induced immune-mediated hepatitis". She worked as a Teaching Fellow at the University of Otago for 2010-2011. She was appointed as a fixed-term Lecturer in Physiology in 2012.
Her current research interests include:
  • interaction between the gut and the liver
  • changes in gut permeability in acute and chronic liver injuries
  • examination of the microcirculation using intravital microscopy
  • the role of stress in acute and chronic liver injuries

Peer Reviewed Journals

  Year Publication
(2013) 'Concanavalin A-induced hepatitis: Gut derived LPS, intestinal permeability and TLR4'
Mallard BL, Mabuchi A, Akashi-Takamura S, Harper J, Quinlan LR, Wheatley AM (2013) 'Concanavalin A-induced hepatitis: Gut derived LPS, intestinal permeability and TLR4'. Hepatology, 58 (S1):966A-966A [Details]
(2013) 'Concanavalin A-Induced Hepatitis in Mice Is Prevented by Depletion of Gut Bacteria Using Antibiotics'
Beth Mallard, Leo R. Quinlan, Ayako Mabuchi, Antony Wheatley (2013) 'Concanavalin A-Induced Hepatitis in Mice Is Prevented by Depletion of Gut Bacteria Using Antibiotics'. Gastroenterology, 144 (5 Supplement 1) [Details]
(2013) 'Depletion of gut bacteria with antibiotics prevents Concanavalin (Con) A induced hepatitis in mice'
Mallard BL, Quinlan L, Mabuchi A, Wheatley AM (2013) 'Depletion of gut bacteria with antibiotics prevents Concanavalin (Con) A induced hepatitis in mice'. Journal Of Hepatology, 58 (Supplement 1):S145-S145 [Details]
(2009) 'Functional Toll-like receptor 4 (TLR4) signaling pathway in T cells and Kupffer cells is essential for Concanavalin (Con) A-induced hepatitis in mice'
Mallard B; Mabuchi A; Harper J; Wheatley AM (2009) 'Functional Toll-like receptor 4 (TLR4) signaling pathway in T cells and Kupffer cells is essential for Concanavalin (Con) A-induced hepatitis in mice'. Journal Of Hepatology, 50 (S1) [Details]
(2006) 'Short-term suppression of elevated growth hormone concentrations following insulin-like growth factor 1 administration in young adults with type 1 diabetes does not alter glomerular filtration or albumin excretion rates'
Williams RM; Yuen K; White D; Mallard B; Dalton RN; Acerini CL; Dunger DB (2006) 'Short-term suppression of elevated growth hormone concentrations following insulin-like growth factor 1 administration in young adults with type 1 diabetes does not alter glomerular filtration or albumin excretion rates'. Clinical Endocrinology, 65 :439-445 [Details]
(2004) 'Role of hepatic stellate cell/hepatocyte interaction and activation of hepatic stellate cells in the early phase of liver regeneration in the rat'
Mabuchi, A; Mullaney I; Sheard PW; Hessian PA; Mallard BL; Tawadrous MN; Zimmermann A; Senoo H; Wheatley AM (2004) 'Role of hepatic stellate cell/hepatocyte interaction and activation of hepatic stellate cells in the early phase of liver regeneration in the rat'. Journal Of Hepatology, 40 (6):910-916 [Details]

Conference Publications

  Year Publication
(2014) Neuroscience Ireland, Young Neuroscientists Symposium
Killilea M, Flannery L, Kerr DM, Mallard B, Wheatley AM, Roche M (2014) LPS-induced locomotor and inflammatory responding in the stress sensitive WKY rat Neuroscience Ireland, Young Neuroscientists Symposium , pp.45-45 [Details]
(2013) Digestive Diseases Week
Mallard, BL; Quinlan LR; Mabuchi, A; Wheatley, AM (2013) Concanavalin A-Induced Hepatitis in Mice is Prevented by Depletion of Gut Bacteria Using Antibiotics Digestive Diseases Week Orlando, Florida, USA, , 18-MAY-13 - 21-MAY-13 [Details]
(2013) International Liver Congress 2013
Mallard, BL; Quinlan L; Mabuchi, A; Wheatley, AM (2013) Depletion of Gut Bacteria With Antibiotics Prevents Concanavalin (Con) A Induced Hepatitis in Mice International Liver Congress 2013 [Details]
(2013) International Union of Physiological Sciences 2013
Muhamad, M; Mabuchi, A; Mallard, B; Ngatiman, H; Wheatley, AM (2013) Microcirulatory Blood Flow During Liver Regeneration After Partial Hepatectomy in LPS-Sensitive and -Insensitive Mice: An IVFM Study International Union of Physiological Sciences 2013 [Details]
(2013) International Union of Physiologal Sciences 2013
Mallard, BL; Mabuchi, A; Quinlan, L; Wheatley, AM. (2013) Concanavalin A-induced immune-mediated liver injury is attenuated by depletion of gastrointestinal bacteria International Union of Physiologal Sciences 2013 [Details]
(2011) 21st Conference of the Asian Pacific Association for the Study of the Liver
Marlini, M; Mabuchi, A; Mallard, BL, Hairulhisyam, MN, Wheatley, AM (2011) Altered microcirculatory blood flow is associated with delayed liver regeneration in TLR4-mutant mice 21st Conference of the Asian Pacific Association for the Study of the Liver [Details]
(2011) 16th International Symposium on Cells of the Hepatic Sinusoid
Mallard, BL; Mabuchi, A; Akashi-Takamura, S; Harper, J; Quinlan LP; Wheatley, AM (2011) New insights into concanavalin A-induced hepatitis: gut microflora, intestinal permeability, and TLR4 16th International Symposium on Cells of the Hepatic Sinusoid [Details]
(2009) 44th Annual Meeting of the European Association for the Study of the Liver
Mallard B; Mabuchi A; Harper J; Wheatley AM (2009) Functional Toll-like receptor 4 (TLR4) signaling pathway in T cells and Kupffer cells is essential for Concanavalin (Con) A-induced hepatitis in mice 44th Annual Meeting of the European Association for the Study of the Liver [Details]
(2007) The Liver Meeting
Mallard BL; Harper J; Mabuchi A; Wheatley AM (2007) Concanavalin A-induced hepatitis is dependent on Toll-like receptor 4 (TLR4) signaling pathways The Liver Meeting [Details]

Published Reports

  Year Publication
(2013) Concanavalin A-induced hepatitis in mice is prevented by depletion of gut bacteria using antibiotics.
Mallard B, Quinlan LR, Mabuchi A, Wheatley AM (2013) Concanavalin A-induced hepatitis in mice is prevented by depletion of gut bacteria using antibiotics. Gastroenterology 144 (Supplement 1), S939, American Gastoenterological Society. [Details]

Meeting

  Year Publication
(2013) DEPLETION OF GUT BACTERIA WITH ANTIBIOTICS PREVENTS CONCANAVALIN (Con) A INDUCED HEPATITIS IN MICE.
Mallard, BL,Quinlan, L,Mabuchi, A,Wheatley, AM (2013) DEPLETION OF GUT BACTERIA WITH ANTIBIOTICS PREVENTS CONCANAVALIN (Con) A INDUCED HEPATITIS IN MICE. Meeting [Details]