Dr. Fabio Quondamatteo M.D.
Contact Details
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Biography:
| 1985-1992: Medical student at Medical School of the University of Bari, Italy, 1992 Title Dottore in Medicina e Chirurgia (University of Bari, Italy) and state examination for italian licence to practice medicine. Sep.1992-Dec.1992 German Primate Centre, Goettingen Jan. 1993- Dec 2006 University of Goettingen, Centre of Anatomy, Dept. of Histology. 1995 German licence to practice medicine 1997 Dr. med. (University of Goettingen, Germany) 1998 Specialist in Anatomy (Medical Association of Lower Saxony, Germany) 2001 Habilitation in Anatomy, i.e. qualification to teach Anatomy at University level (University of Goettingen, Germany). Titel PD (Privatdozent). 2006 Award for best teaching in Anatomy in 2006 (Association of medical students of the University of Goettingen, Germany) 2007 Department of Anatomy, NUI, Galway |
Research Interests
| 1- Cell biological role of extracellular matrix components, basement membranes and their receptors in vivo 2- Cell/matrix interactions and role of Rho GTPases in tuomr progression 3- Normal and pathologic development 4- Biological role of phase II enzymes in metabolism 5- Biology of glycoconjugates |
Peer Reviewed Journals
| Bertossi M, Ribatti D, Mancini L, Virgintino D, Nico B, Quondamatteo F, Marzullo A, Roncali L. (1991) '[Changes in the subendothelial compartment during the maturation process of cerebral microvessels]'. Boll Soc Ital Biol Sper. Italian, 67 (2):159-166. [Details] |
| Ribatti D, Contino R, Quondamatteo F, Formica V, Tursi A. (1992) 'Mast cell populations in the chick embryo lung and their response to compound 48/80 and dexamethasone'. Anat Embryol (Berl), 186 (3):241-244. [Details] |
| Quondamatteo F, Scharif K, Herken R. (1994) 'Changes in laminin immunoreactivity as a marker for the state of liver preservation'. Histochem J, 26 (11):827-832. [Details] |
| Jürgens U, Lu CL, Quondamatteo F. (1996) 'C-fos expression during vocal mobbing in the new world monkey Saguinus fuscicollis'. Eur J Neurosci, 8 (1):2-10. [Details] |
| Michalski S, Quondamatteo F, Meyer E, Schlemminger R, Herken R, Becker HD. (1996) 'Paneth and goblet cells modify their sugar moieties during acute rejection and up to one year after small bowel transplantation in rats'. Transplant Proc, 28 (5):2477-2478. [Details] |
| Quondamatteo F, Götz W, Lübben U, Herken R. (1997) 'Changes in lectin binding sites during early human liver development'. Histochem Cell Biol, 107 (3):223-228. [Details] |
| Nico B, Quondamatteo F, Ribatti D, Bertossi M, Russo G, Herken R, Roncali L. (1998) 'Ultrastructural localization of lectin binding sites in the developing brain microvasculature'. Anat Embryol (Berl), 197 (4):305-315. [Details] |
| Ribatti D, Vacca A, Nico B, Quondamatteo F, Herken R, Roncali L. (1998) 'Free laminin in the extracellular matrix of B-cell non Hodgkin's lymphomas'. J Submicrosc Cytol Pathol, 30 (3):459-461. [Details] |
| Miosge N, Götz W, Quondamatteo F, Herken R. (1998) 'Comparison of lectin binding patterns in malformed and normal human embryos and fetuses'. Teratology, 57 (2):85-92. [Details] |
| Quondamatteo F, Michalski S, Wesling F, Miosge N, Schlemminger R, Herken R. (1998) 'Laminin localization in enterocytic basement membrane of rat small bowel grafts. A light and electron microscopic study'. Matrix Biol, 17 ((8-9)):647-655. [Details] |
| Miosge N, Waletzko K, Bode C, Quondamatteo F, Schultz W, Herken R. (1998) 'Light and electron microscopic in-situ hybridization of collagen type I and type II mRNA in the fibrocartilaginous tissue of late-stage osteoarthritis'. Osteoarthritis Cartilage, 6 (4):278-285. [Details] |
| Quondamatteo F, Schulz TG, Bunzel N, Hallier E, Herken R. (1998) 'Immunohistochemical localization of glutathione S-transferase-T1 in murine kidney, liver, and lung'. Histochem Cell Biol, 110 (4):417-423. [Details] |
| Ribatti D, Vacca A, Nico B, Quondamatteo F, Ria R, Minischetti M, Marzullo A, Herken R, Roncali L, Dammacco F. (1999) 'Bone marrow angiogenesis and mast cell density increase simultaneously with progression of human multiple myeloma'. Br J Cancer, 79 ((3-4)):451-455. [Details] |
| Quondamatteo F, Scherf C, Miosge N, Herken R. (1999) 'Immunohistochemical localization of laminin, nidogen, and type IV collagen during the early development of human liver'. Histochem Cell Biol, 111 (1):39-47. [Details] |
| Nico B, Quondamatteo F, Herken R, Marzullo A, Corsi P, Bertossi M, Russo G, Ribatti D, Roncali L. (1999) 'Developmental expression of ZO-1 antigen in the mouse blood-brain barrier'. Brain Res Dev Brain Res, 114 (2):161-169. [Details] |
| Braun F, Quondamatteo F, Bothuri P, Hosseini M, Laabs S, Sattler B, Ringe B. (1999) 'Determination of intestinal alpha-glutathione S-transferase after ischemia-reperfusion injury'. Acta Gastroenterol Belg, 62 (2):229-233. [Details] |
| Quondamatteo F, Knittel T, Mehde M, Ramadori G, Herken R. (1999) 'Matrix metalloproteinases in early human liver development'. Histochem Cell Biol, 112 (4):277-282. [Details] |
| Neubauer K, Krüger M, Quondamatteo F, Knittel T, Saile B, Ramadori G. (1999) 'Transforming growth factor-beta1 stimulates the synthesis of basement membrane proteins laminin,collagen type IV and entactin in rat liver sinusoidal endothelial cells'. J Hepatol, 31 (4):692-702. [Details] |
| Vacca A, Ribatti D, Ruco L, Giacchetta F, Nico B, Quondamatteo F, Ria R, Iurlaro M, Dammacco F. (1999) 'Angiogenesis extent and macrophage density increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas'. Br J Cancer, 79 ((5-6)):965-970. [Details] |
| Brakebusch C, Grose R, Quondamatteo F, Ramirez A, Jorcano JL, Pirro A, Svensson M, Herken R, Sasaki T,Timpl R, Werner S, Fässler R. (2000) 'Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes'. EMBO J, 19 (15):3990-4003. [Details] |
| Quondamatteo F, Zieger J, Götz W, Miosge N, Herken R. (2000) 'Extensive glycosylation changes revealed by lectin histochemistry in morphologically normal prenatal tissues of the mouse mutant undulated (un/un)'. Anat Rec, 258 (3):243-251. [Details] |
| Miosge N, Quondamatteo F, Klenczar C, Herken R. (2000) 'Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo'. J Histochem Cytochem, 48 (2):229-238. [Details] |
| Nico B, Quondamatteo F, Herken R, Blumchen T, Defazio G, Giorelli M, Livrea P, Marzullo A, Russo G, Ribatti D, Roncali L. (2000) 'Interferon beta-1a prevents the effects of lipopolysaccharide on embryonic brain microvessels'. Brain Res Dev Brain Res, 119 (2):231-242. [Details] |
| Nicchia GP, Frigeri A, Liuzzi GM, Santacroce MP, Nico B, Procino G, Quondamatteo F, Herken R, Roncali L,Svelto M. (2000) 'Aquaporin-4-containing astrocytes sustain a temperature- and mercury-insensitive swelling in vitro'. Glia, 31 (1):29-38. [Details] |
| Nico B, Frigeri A, Nicchia GP, Quondamatteo F, Herken R, Errede M, Ribatti D, Svelto M, Roncali L. (2001) 'Role of aquaporin-4 water channel in the development and integrity of the blood-brain barrier'. J Cell Sci, 114 ((Pt 7)):1297-1307. [Details] |
| Götz W, Quondamatteo F. (2001) 'Glycoconjugate distribution in early human notochord and axial mesenchyme'. Acta Histochem, 103 (1):21-35. [Details] |
| Frigeri A, Nicchia GP, Nico B, Quondamatteo F, Herken R, Roncali L, Svelto M. (2001) 'Aquaporin-4 deficiency in skeletal muscle and brain of dystrophic mdx mice'. FASEB J, 15 (1):90-98. [Details] |
| Quondamatteo F, Reinhardt DP, Charbonneau NL, Pophal G, Sakai LY, Herken R. (2002) 'Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development'. Matrix Biol, 21 (8):637-646. [Details] |
| F. Quondamatteo, D.P. Reinhardt, N.L. Charbonneau, G. Pophal, L.Y. Sakai, R. Herken. (2002) 'Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development. (color figures in Matrix Biol 2003, 22:93-96)'. MATRIX BIOLOGY, 21 :637-646. [Details] |
| Quondamatteo F. (2002) 'Assembly, stability and integrity of basement membranes in vivo'. Histochem J Review, 34 ((8-9)):369-381. [Details] |
| Nico B, Frigeri A, Nicchia GP, Corsi P, Ribatti D, Quondamatteo F, Herken R, Girolamo F, Marzullo A, Svelto M, Roncali L. (2003) 'Severe alterations of endothelial and glial cells in the blood-brain barrier of dystrophic mdx mice'. Glia, 42 (3):235-251. [Details] |
| M. Ellies, R. Laskawi, S. Schütz, F. Quondamatteo. (2003) 'Immunohistochemical evidence of nNOS and changes after intraglandular application of botulinum toxin A in cephalic salivary glands of adult rats'. 65 :140-143. [Details] |
| Ellies M, Laskawi R, Schütz S, Quondamatteo F. (2003) 'Immunohistochemical evidence of nNOS and changes after intraglandular application of botulinum toxin A in cephalic salivary glands of adult rats'. ORL J Otorhinolaryngol Relat Spec, 65 (3):140-143. [Details] |
| B. Nico, A. Frigeri, G.P. Nicchia, P. Corsi, D. Ribatti, F. Quondamatteo, R. Herken, F. Girolamo, A. Marzullo , M. Svelto, L. Roncali. (2003) 'Severe alterations of endothelial and glial cells in the blood-brain barrier of dystrophic mdx mice'. 42 :235-251. [Details] |
| F. Quondamatteo, C. Kempkensteffen, N. Miosge, A. Sonnenberg, R. Herken. (2004) 'Ultrastructural localization of integrin subunits alpha3 and alpha6 in capillarized sinusoids of the human cirrhotic liver'. HISTOLOGY AND HISTOPATHOLOGY, 19 :799-806. [Details] |
| Cozzolino M, Ferraro E, Ferri A, Rigamonti D, Quondamatteo F, Ding H, Xu ZS, Ferrari F, Angelini DF, RotilioG, Cattaneo E, Carrì MT, Cecconi F. (2004) 'Apoptosome inactivation rescues proneural and neural cells from neurodegeneration'. Cell Death Differ, 11 (11):1179-1191. [Details] |
| M. Cozzolino, E. Ferraro, A. Ferri, D. Rigamonti, F. Quondamatteo, H. Ding, ZS Xu, F. Ferrari, D.F. Angelini, G. Rotilio, E. Cattaneo, M.T. Carri, F. Cecconi. (2004) 'Apoptosome inactivation rescues proneural and neural cells from neurodegeneration'. CELL DEATH AND DIFFERENTIATION, 11 :1179-1191. [Details] |
| Quondamatteo F, Kempkensteffen C, Miosge N, Sonnenberg A, Herken R. (2004) 'Ultrastructural localization of integrin subunits alpha3 and alpha6 in capillarized sinusoids of the human cirrhotic liver'. Histol Histopathol, 19 (3):799-806. [Details] |
| Müller M, Berger J, Gersdorff N, Cecconi F, Herken R, Quondamatteo F. (2005) 'Localization of Apaf1 gene expression in the early development of the mouse by means of in situreverse transcriptase-polymerase chain reaction'. Dev Dyn, 234 (1):215-221. [Details] |
| M. Müller, J. Berger, N. Gersdorf, F. Cecconi, R. Herken, F. Quondamatteo. (2005) 'Localization of gene expression of the apoptotic protein activating factor 1 (apaf-1) in the early development of the mouse using in-situ RT-PCR'. 234 :215-221. [Details] |
| Chrostek A, Wu X, Quondamatteo F, Hu R, Sanecka A, Niemann C, Langbein L, Haase I, Brakebusch C. (2006) 'Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis'. Mol Cell Biol, 26 (18):6957-6970. [Details] |
| Ellies M, Schütz S, Quondamatteo F, Laskawi R. (2006) 'The effect of local injection of botulinum toxin A on the immunoreactivity of nNOS in the rat submandibular gland: an immunohistochemical study'. Int J Pediatr Otorhinolaryngol, 70 (1):59-63. [Details] |
| Wu X, Quondamatteo F, Lefever T, Czuchra A, Meyer H, Chrostek A, Paus R, Langbein L, Brakebusch C. (2006) 'Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin'. Genes Dev, 20 (5):571-585. [Details] |
| Tomte LT, Annatshah Y, Schlüter NK, Miosge N, Herken R, Quondamatteo F. (2006) 'Hematopoietic cells are a source of nidogen-1 and nidogen-2 during mouse liver development'. J Histochem Cytochem, 54 (5):593-604. [Details] |
| Ellies M, Schütz S, Quondamatteo F, Laskawi R. (2006) 'Immunohistochemical investigations of the influence of botulinum toxin A on the immunoreactivity of nNOS in the parotid gland of the rat'. J Oral Maxillofac Surg, 64 (3):397-401. [Details] |
| Quondamatteo F, Krick W, Hagos Y, Krüger MH, Neubauer-Saile K, Herken R, Ramadori G, BurckhardtG, Burckhardt BC. (2006) 'Localization of the sulfate/anion exchanger in the rat liver'. Am J Physiol Gastrointest Liver Physiol, 290 (5). [DOI] [Details] |
| A. Diedrich, H.C. Bock, F. König, T.G. Schulz, H.C. Ludwig, R. Herken, F. Quondamatteo. (2006) 'Expression of glutathione S-transferase T1 (GSTT1) in human brain tumours'. HISTOLOGY AND HISTOPATHOLOGY, 21 :1199-1207. [Details] |
| L.T. Tomte, Y. Annatshah, N.K. Schlüter, N. Miosge, R. Herken, F. Quondamatteo. (2006) 'Hematopoietic cells are a source of nidogen-1 and nidogen-2 during mouse liver development'. 54 :593-604. [Details] |
| M. Ellies, S. Schütz, F. Quondamatteo, R. Laskawi. (2006) 'Immunohistochemical investigations on the influence of botulinum toxin A on the immunoreactivity of nNOS in the parotid gland of the rat'. 64 :397-401. [Details] |
| M. Ellies, S. Schütz, F. Quondamatteo, R. Laskawi. (2006) 'The effect of local injection of botulinum toxin A on the immunoreactivity of nNOS in the rat submandibular gland: An immunohistochemical study'. 70 :59-63. [Details] |
| F. Quondamatteo, W. Krick, Y. Hagos , M.H. Krüger, K. Neubauer-Saile, R. Herken , G. Ramadori, G. Burckhardt, B.C. Burckhardt. (2006) 'Localization of the sulfate-anion exchanger (sat-1) in rat liver'. AMERICAN JOURNAL OF PHYSIOLOGY, 290 :G1075-1081. [Details] |
| X. Wu, F. Quondamatteo, T. Lefever, A. Czuchra, H. Meyer, A.Chrostek, R. Paus, L. Langbein, C. Brakebusch. (2006) 'Cdc 42 controls progenitor cell differentiation and beta-catenin turnover in skin'. GENES AND DEVELOPMENT, 20 :571-585. [Details] |
| X. Wu, F. Quondamatteo, C. Brakebusch (2006) 'Cdc42 expression in keratinocytes is required for the maintenance of the basement membrane in skin'. MATRIX BIOLOGY, 25 :466-474. [Details] |
| A. Chrostek, X.Wu, F. Quondamatteo, R. Hu, A. Sanecka, C. Niemann, L. Langbein, I. Haase, C. Brakebusch. (2006) 'Rac-1 is crucial for hair follicle integrity but is not essential for the maintainance of the epidermis'. MOLECULAR AND CELLULAR BIOLOGY, 26 :6957-6970. [Details] |
| Wu X, Quondamatteo F, Brakebusch C. (2006) 'Cdc42 expression in keratinocytes is required for the maintenance of the basement membrane in skin'. Matrix Biol, 25 (8):466-474. [Details] |
| M.C. Zweers, J. M. Davidson, A. Pozzi, R. Hallinger, K. Janz, F. Quondamatteo, B. Leutgeb, T. Krieg, B. Eckes (2007) 'Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization'. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 127 :467-478. [Details] |
| Zweers MC, Davidson JM, Pozzi A, Hallinger R, Janz K, Quondamatteo F, Leutgeb B, Krieg T, Eckes B. (2007) 'Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization'. J Invest Dermatol, 127 (2):467-478. [Details] |
| Broderick BJ, Corley GJ, Quondamatteo F, Grace PA, Breen PP, Olaighin G. (2008) 'A haemodynamic study of the physiological mechanisms of the venous pump in the healthy human foot'. Conf Proc IEEE Eng Med Biol Soc, :1411-1414. [Details] |
| van Hengel J, D'Hooge P, Hooghe B, Wu X, Libbrecht L, De Vos R, Quondamatteo F, Klempt M, Brakebusch C, van Roy F. (2008) 'Continuous cell injury promotes hepatic tumorigenesis in cdc42-deficient mouse liver'. Gastroenterology, 134 (3):781-792. [Details] |
| Fricke M, Langer C, Brunner E, Sakai LY, Füzesi L, Reinhardt DP, Quondamatteo F. (2008) 'Fibrillin-1 in incisional hernias: an immunohistochemical study in scar and non-scar regions of human skin and muscle fasciae'. J Anat, 212 (5):674-685. [DOI] [Details] |
| Bîrlea SI, Corley GJ, Bîrlea NM, Breen PP, Quondamatteo F, OLaighin G. (2009) 'Detecting electroporation by assessing the time constants in the exponential response of human skin to voltage controlled impulse electrical stimulation'. Conf Proc IEEE Eng Med Biol Soc, :1355-1358. [Details] |
| Broderick BJ, Corley GJ, Quondamatteo F, Breen PP, Serrador J, Ólaighin G. (2010) 'Venous emptying from the foot: influences of weight bearing, toe curls, electrical stimulation, passive compression, and posture'. J Appl Physiol, 109 (4):1045-1052. [Details] |
| Kane MJ, Breen PP, Quondamatteo F, ÓLaighin G. (2010) 'BION microstimulators: a case study in the engineering of an electronic implantable medical device'. Med Eng Phys, 33 (1):7-16. [Details] |
| Lefever T, Pedersen E, Basse A, Paus R, Quondamatteo F, Stanley AC, Langbein L, Wu X, Wehland J,Lommel S, Brakebusch C (2010) 'N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGF{beta} pathways'. J Cell Sci, 123 ((Pt 1)):128-140. [Details] |
| Corley GJ, Broderick BJ, Nestor SM, Breen PP, Grace PA, Quondamatteo F, Olaighin G. (2010) 'The anatomy and physiology of the venous foot pump'. Anat Rec, 293 (3):370-378. [Details] |
| Jackson B, Peyrollier K, Pedersen E, Basse A, Karlsson R, Wang Z, Lefever T, Ochsenbein AM, Schmidt G, Aktories K, Stanley A, Quondamatteo F, Ladwein M, Rottner K, van Hengel J, Brakebusch C. (2011) 'RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes'. Mol Biol Cell, 22 (5):593-605. [DOI] [Details] |
Conference Paper
| QUONDAMATTEO, F. Gordon Conference on Basement Membranes. P= poster as a first author. Conference Paper [Details] |
| QUONDAMATTEO, F. FECTS (Federation of European Connective Tissues Societies)-Meeting P=poster as a first author. Conference Paper [Details] |
| QUONDAMATTEO, F. Arbeitstagung der Arbeitsgemeinschaft für Teratologie, Greifswald. Conference Paper [Details] |
| QUONDAMATTEO, F. Arbeitstagung der Anatomischen Gesellschaft, Würzburg. Conference Paper [Details] |
| QUONDAMATTEO, F. Congresso Nazionale della Societa' Italiana di Anatomia. Conference Paper [Details] |
| QUONDAMATTEO, F. Workshop Programmed Cell Death, Villa Vigoni. Conference Paper [Details] |
| QUONDAMATTEO, F. Meeting of the German Connective Tissue Society. P= poster as a first or last author. Conference Paper [Details] |
| QUONDAMATTEO, F. GLYCO XIV, International Symposium on Glycoconjugates. P=poster as a first author. Conference Paper [Details] |
| QUONDAMATTEO, F. Meeting of the Society for Histochemistry P=poster as a first author. Conference Paper [Details] |
| QUONDAMATTEO, F. Hauptversammlung der Anatomischen Gesellschaft. Conference Paper [Details] |