Francis Finucane

Clinical Lecturer

Contact Details

Senior Lecturer
Medicine
Bariatric Medicine Service
Department of Diabetes, Endocrinology and Metabolism
Galway University Hospitals
Saolta University Health Care Group

 
researcher

Biography

Francis Finucane is a consultant endocrinologist at Galway University Hospitals and an honorary senior lecturer in medicine at NUI Galway.  Prior to this he was awarded an MD from the University of Dublin (TCD) for research on the mechanistic basis for type 2 diabetes in young people.  Thereafter, he completed an MRC-funded post-doctoral career development fellowship at the Institute of Metabolic Science in Cambridge, UK.

Since returning to Ireland in 2010, Dr. Finucane has established a regional bariatric service for patients with severe and complicated obesity.  He chairs the regional Diabetes Service Implementation Group for the West of Ireland, is a member of the National Clinical Advisory Group for Diabetes and is the clinical lead for endocrinology for the Saolta University Health Care Group.

Peer Reviewed Journals

  Year Publication
(2014) 'Liver fat accumulation is associated with reduced hepatic insulin extraction and beta cell dysfunction in healthy older individuals'
Finucane, F. M.,Sharp, S. J.,Hatunic, M.,Sleigh, A.,De Lucia Rolfe, E.,Aihie Sayer, A.,Cooper, C.,Griffin, S. J.,Wareham, N. J. (2014) 'Liver fat accumulation is associated with reduced hepatic insulin extraction and beta cell dysfunction in healthy older individuals'. Diabetology & metabolic syndrome, 6 (11) [Details]
(2013) 'Differences in the structure of outpatient diabetes care between endocrinologist-led and general physician- led services'
O'Donnell, M,de Siun, A,O'Mullane, M,Smith, D,Bradley, C,Finucane, FM,Dinneen, SF (2013) 'Differences in the structure of outpatient diabetes care between endocrinologist-led and general physician- led services'. BMC Health Services Research, 13 [DOI] [Details]
(2011) 'Genetic defects in human pericentrin are associated with severe insulin resistance and diabetes.Osteodysplastic Primordial Dwarfism Study Group'
Huang-Doran I, Bicknell LS, Finucane FM, Rocha N, Porter KM, Tung YC, Szekeres F, Krook A, Nolan JJ, O'Driscoll M, Bober M, O'Rahilly S, Jackson AP, Semple RK, Majewski (2011) 'Genetic defects in human pericentrin are associated with severe insulin resistance and diabetes.Osteodysplastic Primordial Dwarfism Study Group'. Diabetes, 60 (3):925-935 [DOI] [Details]
(2011) 'Reduced insulin requirements during participation in the DAFNE (dose adjustment for normal eating) structured education programme'
Leelarathna L, Ward C, Davenport K, Donald S, Housden A, Finucane FM, Evans M. (2011) 'Reduced insulin requirements during participation in the DAFNE (dose adjustment for normal eating) structured education programme'. Diabetes Res Clin Pract, 92 (2):e34-e36 [DOI] [Details]
(2011) 'Protocol for the ADDITION-Plus study: a randomised controlled trial of an individually-tailored behaviour change intervention among people with recently diagnosed type 2 diabetes under intensive UK general practice care'
Griffin SJ, Simmons RK, Williams KM, Prevost AT, Hardeman W, Grant J, Whittle F, Boase S, Hobbis I, Brage S, Westgate K, Fanshawe T, Sutton S, Wareham NJ, Kinmonth AL, ADDITION-Plus study team. (2011) 'Protocol for the ADDITION-Plus study: a randomised controlled trial of an individually-tailored behaviour change intervention among people with recently diagnosed type 2 diabetes under intensive UK general practice care'. BMC Public Health, 11 [DOI] [Details]
(2010) 'Validation of the historical adulthood physical activity questionnaire (HAPAQ) against objective measurements of physical activity'
Besson H, Harwood CA, Ekelund U, Finucane FM, McDermott CJ, Shaw PJ, Wareham NJ. (2010) 'Validation of the historical adulthood physical activity questionnaire (HAPAQ) against objective measurements of physical activity'. Int J Behav Nutr Phys Act, 7 (54) [DOI] [Details]
(2010) 'The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial'
Finucane FM, Sharp SJ, Purslow LR, Horton K, Horton J, Savage DB, Brage S, Besson H, De Lucia Rolfe E, Sleigh A, Martin HJ, Aihie Sayer A, Cooper C, Ekelund U, Griffin SJ, Wareham NJ. (2010) 'The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial'. Diabetologia, 53 (4):624-631 [DOI] [Details]
(2010) 'Glucose metabolism after normalization of markers of iron overload by venesection in subjects with hereditary hemochromatosis'
Hatunic M, Finucane FM, Norris S, Pacini G, Nolan JJ. (2010) 'Glucose metabolism after normalization of markers of iron overload by venesection in subjects with hereditary hemochromatosis'. Metabolism, 59 (12):1811-1815 [DOI] [Details]
(2010) 'Altered C-fiber function as an indicator of early peripheral neuropathy in individuals with impaired glucose tolerance'
Green AQ, Krishnan S, Finucane FM, Rayman G. (2010) 'Altered C-fiber function as an indicator of early peripheral neuropathy in individuals with impaired glucose tolerance'. Diabetes Care, 33 (1):174-176 [DOI] [Details]
(2010) 'Effect of iron overload on glucose metabolism in patients with hereditary hemochromatosis'
Hatunic M, Finucane FM, Brennan AM, Norris S, Pacini G, Nolan JJ. (2010) 'Effect of iron overload on glucose metabolism in patients with hereditary hemochromatosis'. Metabolism, 59 (3):380-384 [DOI] [Details]
(2010) 'Caesarean section and macrosomia increase transient tachypnoea of the newborn in type 1 diabetes pregnancies'
Al-Agha R, Kinsley BT, Finucane FM, Murray S, Daly S, Foley M, Smith SC, Firth RG. (2010) 'Caesarean section and macrosomia increase transient tachypnoea of the newborn in type 1 diabetes pregnancies'. Diabetes Res Clin Pract, 89 (3):e46-e48 [DOI] [Details]
(2010) 'Ultrasound measurements of visceral and subcutaneous abdominal thickness to predict abdominal adiposity among older men and women'
De Lucia Rolfe E, Sleigh A, Finucane FM, Brage S, Stolk RP, Cooper C, Sharp SJ, Wareham NJ, Ong KK. (2010) 'Ultrasound measurements of visceral and subcutaneous abdominal thickness to predict abdominal adiposity among older men and women'. Obesity (Silver Spring), 18 (3):625-631 [DOI] [Details]
(2010) 'Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1{alpha}/Mitofusin-2 regulatory pathway in response to physical activity'
Hernández-Alvarez MI, Thabit H, Burns N, Shah S, Brema I, Hatunic M, Finucane F, Liesa M, Chiellini C, Naon D, Zorzano A, Nolan JJ. (2010) 'Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1{alpha}/Mitofusin-2 regulatory pathway in response to physical activity'. Diabetes Care, 33 (3):645-651 [DOI] [Details]
(2009) 'An intensive nurse-led, multi-interventional clinic is more successful in achieving vascular risk reduction targets than standard diabetes care'
MacMahon Tone J, Agha A, Sherlock M, Finucane F, Tormey W, Thompson CJ. (2009) 'An intensive nurse-led, multi-interventional clinic is more successful in achieving vascular risk reduction targets than standard diabetes care'. Ir J Med Sci, 178 (2):179-186 [DOI] [Details]
(2009) 'Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial'
Finucane FM, Horton J, Purslow LR, Savage DB, Brage S, Besson H, Horton K, Rolfe Ede L, Sleigh A, Sharp SJ, Martin HJ, Sayer AA, Cooper C, Ekelund U, Griffin SJ, Wareham NJ. (2009) 'Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial'. BMC Endocr Disord, 19 (9) [DOI] [Details]
(2009) 'Obesity is associated with altered lung function independently of physical activity and fitness'
Steele RM, Finucane FM, Griffin SJ, Wareham NJ, Ekelund U. (2009) 'Obesity is associated with altered lung function independently of physical activity and fitness'. Obesity (Silver Spring), 17 (3):578-584 [DOI] [Details]
(2009) 'Incidence and pathophysiology of severe hyponatraemia in neurosurgical patients'
Sherlock M, O'Sullivan E, Agha A, Behan LA, Owens D, Finucane F, Rawluk D, Tormey W, Thompson CJ. (2009) 'Incidence and pathophysiology of severe hyponatraemia in neurosurgical patients'. Postgrad Med J, 85 (1002):171-175 [DOI] [Details]
(2009) 'Altered respiratory function is associated with increased metabolic risk, independently of adiposity, fitness and physical activity'
Steele RM, Finucane FM, Simmons RK, Griffin SJ, Wareham NJ, Ekelund U, ProActive research team. (2009) 'Altered respiratory function is associated with increased metabolic risk, independently of adiposity, fitness and physical activity'. Diabet Med, 26 (4):362-369 [DOI] [Details]
(2009) 'European Group for the Study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular Disease Risk Study Group), Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals'
Finucane FM, Luan J, Wareham NJ, Sharp SJ, O'Rahilly S, Balkau B, Flyvbjerg A, Walker M, Højlund K, Nolan JJ, Savage DB. (2009) 'European Group for the Study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular Disease Risk Study Group), Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals'. Diabetologia, 52 (11):2345-2349 [DOI] [Details]
(2009) 'Obesity in Irish youth: epidemiology and implications'
Finucane FM. (2009) 'Obesity in Irish youth: epidemiology and implications'. Ir J Med Sci, 178 (3):249-255 [DOI] [Details]
(2008) 'Propylthiouracil induced C-ANCA positive agranulocytosis complicating Graves' thyrotoxicosis in pregnancy'
Finucane FM, O'Connell J, Kinsley BT. (2008) 'Propylthiouracil induced C-ANCA positive agranulocytosis complicating Graves' thyrotoxicosis in pregnancy'. Ir J Med Sci, 177 (1):69-71 [DOI] [Details]
(2008) 'Plasma visfatin is reduced after aerobic exercise in early onset type 2 diabetes mellitus'
Brema I, Hatunic M, Finucane F, Burns N, Nolan JJ, Haider D, Wolzt M, Ludvik B. (2008) 'Plasma visfatin is reduced after aerobic exercise in early onset type 2 diabetes mellitus'. Diabetes Obes Metab, 10 (7):600-602 [DOI] [Details]
(2008) 'Adverse metabolic profiles in a cohort of obese Irish children'
Finucane FM, Teong L, Pittock S, Fallon M, Hatunic M, Costigan C, Murphy N, Crowley VE, Nolan JJ. (2008) 'Adverse metabolic profiles in a cohort of obese Irish children'. Ann Clin Biochem, :206-209 [DOI] [Details]
(2008) 'Genomic variants at the PINK1 locus are associated with transcript abundance and plasma nonesterified fatty acid concentrations in European whites'
Franks PW, Scheele C, Loos RJ, Nielsen AR, Finucane FM, Wahlestedt C, Pedersen BK, Wareham NJ, Timmons JA. (2008) 'Genomic variants at the PINK1 locus are associated with transcript abundance and plasma nonesterified fatty acid concentrations in European whites'. FASEB J, 22 (9):3135-3145 [DOI] [Details]
(2008) 'Clinical insights into the safety and utility of the insulin tolerance test (ITT) in the assessment of the hypothalamo-pituitary-adrenal axis'
Finucane FM, Liew A, Thornton E, Rogers B, Tormey W, Agha A. (2008) 'Clinical insights into the safety and utility of the insulin tolerance test (ITT) in the assessment of the hypothalamo-pituitary-adrenal axis'. Clin Endocrinol (Oxf), 69 (4):603-607 [DOI] [Details]
(2007) 'Vascular inflammatory markers in early-onset obese and type 2 diabetes subjects before and after three months' aerobic exercise training'
Hatunic M, Finucane F, Burns N, Gasparro D, Nolan JJ. (2007) 'Vascular inflammatory markers in early-onset obese and type 2 diabetes subjects before and after three months' aerobic exercise training'. Diab Vasc Dis Res, 4 (3):231-234 [DOI] [Details]
(2007) 'Early-onset type 2 diabetes in obese white subjects is characterised by a marked defect in beta cell insulin secretion, severe insulin resistance and a lack of response to aerobic exercise training'
Burns N, Finucane FM, Hatunic M, Gilman M, Murphy M, Gasparro D, Mari A, Gastaldelli A, Nolan JJ. (2007) 'Early-onset type 2 diabetes in obese white subjects is characterised by a marked defect in beta cell insulin secretion, severe insulin resistance and a lack of response to aerobic exercise training'. Diabetologia, 50 (7):1500-1508 [DOI] [Details]
(2007) 'Attendance at an Irish diabetes dietetic outpatient clinic'
Finucane FM, Gaffney L, Hatunic M, Burns N, Nolan JJ. (2007) 'Attendance at an Irish diabetes dietetic outpatient clinic'. Diabetes Res Clin Pract, 77 (2):335-336 [DOI] [Details]
(2006) 'Cerebral aneurysms'
Finucane FM. (2006) 'Cerebral aneurysms'. N Engl J Med author reply 2705, 355 (25) [DOI] [Details]
(2005) 'Contrasting clinical and cardiovascular risk status between early and later onset type 2 diabetes'
Hatunic M, Burns N, Finucane F, Mannion C, Nolan JJ. (2005) 'Contrasting clinical and cardiovascular risk status between early and later onset type 2 diabetes'. Diab Vasc Dis Res, 2 (2):73-75 [DOI] [Details]
(2004) 'Attenuation of vasopressin-induced antidiuresis in poorly controlled type 2 diabetes'
Agha A, Smith D, Finucane F, Sherlock M, Morris A, Baylis P, Thompson CJ. (2004) 'Attenuation of vasopressin-induced antidiuresis in poorly controlled type 2 diabetes'. Am J Physiol Endocrinol Metab, 287 (6):e1100-E1106 [DOI] [Details]
(2004) 'Abnormal regulation of thirst and vasopressin secretion following surgery for craniopharyngioma'
Smith D, Finucane F, Phillips J, Baylis PH, Finucane J, Tormey W, Thompson CJ. (2004) 'Abnormal regulation of thirst and vasopressin secretion following surgery for craniopharyngioma'. Clin Endocrinol (Oxf), 61 (2):273-279 [DOI] [Details]
(2004) 'Conventional glucocorticoid replacement overtreats adult hypopituitary patients with partial ACTH deficiency'
Agha A, Liew A, Finucane F, Baker L, O'Kelly P, Tormey W, Thompson CJ. (2004) 'Conventional glucocorticoid replacement overtreats adult hypopituitary patients with partial ACTH deficiency'. Clin Endocrinol (Oxf), 60 (6):688-693 [DOI] [Details]

Meeting

  Year Publication
(2012) Medication Costs for Patients with Type 2 Diabetes Mellitus: How They Vary with Body Mass Index Status, Age, Gender and Co-morbidity.
Queally, M,O'Neill, C,Finucane, FM (2012) Medication Costs for Patients with Type 2 Diabetes Mellitus: How They Vary with Body Mass Index Status, Age, Gender and Co-morbidity. Meeting [Details]
(2012) The Influence of Body Mass Index on All-cause Mortality in Patients with Established Cardiovascular Disease.
Fitzgibbon, MS,Iglesias, AA,Glynn, LG,Murphy, AW,Finucane, FM (2012) The Influence of Body Mass Index on All-cause Mortality in Patients with Established Cardiovascular Disease. Meeting [Details]