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About NUI Galway
About NUI Galway
Since 1845, NUI Galway has been sharing the highest quality teaching and research with Ireland and the world. Find out what makes our University so special – from our distinguished history to the latest news and campus developments.
Colleges & Schools
Colleges & Schools
NUI Galway has earned international recognition as a research-led university with a commitment to top quality teaching across a rang of key areas of expertise.
Business & Industry
Guiding Breakthrough Research at NUI Galway
We explore and facilitate commercial opportunities for the research community at NUI Galway, as well as facilitating industry partnership.
- Alumni, Friends & Supporters
At NUI Galway, we believe that the best learning takes place when you apply what you learn in a real world context. That's why many of our courses include work placements or community projects.
Dr Karl McCullagh B.Sc, M.Sc, Ph.D.
| Muscle biology and plasticity
Adeno-associated virus gene delivery in vivo
Peer Reviewed Journals
|McCullagh, KJA and Perlingeiro, R (2014) 'Coaxing Stem Cells for Skeletal Muscle repair'. Advanced Drug Delivery Reviews, . [Details]|
|Ganly S, Hynes SO, Sharif F, Aied A, Barron V, McCullagh K, McMahon J, McHugh P, Crowley J, Wang W, O'Brien T, Greiser U (2013) 'Liposomal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'. J Control Release, 167 (2):109-119. [Details]|
|Sharif, F,Hynes, SO,McCullagh, KJA,Ganley, S,Greiser, U,McHugh, P,Crowley, J,Barry, F,O'Brien, T (2012) 'Gene-eluting stents: non-viral, liposome-based gene delivery of eNOS to the blood vessel wall in vivo results in enhanced endothelialization but does not reduce restenosis in a hypercholesterolemic model'. Gene Therapy, 19 :321-328. [DOI] [Details]|
|McCullagh, Karl JA (2012) 'Can a young muscle’s stem cell secretome prolong our lives?'. Stem Cell Research & Therapy, 3 (3). [ARAN Link] [Details]|
|Sharif F, Hynes S, McCullagh KJA, Ganley S, Geiser U, McHugh P, Crowley J, Barry F, O'Brien T. (2012) 'Gene-Eluting Stents: liposome-based eNOS enhances re-endothelialisation but does not prevent restenosis in a hypercholesterolemic model'. Gene Therapy. Impact Factor 4.8, . [Details]|
|WT Clarke, B Edwards, KJA McCullagh, MW Kemp, C Moorwood, DL Sherman, M Burgress and KE Davies. (2010) 'Syncoilin modulates peripherin filament networks and is necessary for large- calibre motor neurons'. Journal of Cell Science. Cover Issue (Impact factor:6.1), 123 :2543-2552. [Details]|
|Karl JA McCullagh, Ben Edwards, Matthew W. Kemp, Laura C. Giles, Matthew Burges and Kay E. Davies (2008) 'Analysis of skeletal muscle function in the C57BL6/SV129 syncoilin knockout mouse'. Mammalian Genome (Impact factor: 2.94), 19 (5):339-351. [Details]|
|Karl JA McCullagh, Ben Edwards, Richard M. Lovering, Ellen Poon, Denise Paulin and Kay E Davies. (2007) 'Intermediate filament-like protein syncoilin in normal and myopathic striated muscle. Neuromuscular Disorders'. Neuromuscular Disorders (Impact factor:2.98), 17 ((11-12)):970-979. [Details]|
|Lara-Pezzi E, Paul A, Winn N, McCullagh KJA, Slominsky E, Paola Santini M, Mourkioti F, Fukushima S, Suzuki K and Rosenthal N. (2007) 'A naturally occurring calcineurin variant inhibits FoxO activity and enhances skeletal muscle regeneration'. J. Cell. Biol (Impact factor:9.57), 179 (6):1205-1218. [Details]|
|Nowak K, McCullagh K, Poon E, Davies KE. (2005) 'Muscular dystrophies related to the cytoskeleton/nuclear envelope'. Novartis Found Symp discussion 112-7, 227-30. Review, :227-230. [Details]|
|Hirst, RC, McCullagh, KJA., Davies KE (2005) 'Utrophin upregulation in Duchenne muscular dystrophy'. Acta Myologica Review, 24 (3):209-216. [Details]|
|McCullagh KJ, Calabria E, Pallafacchina G, Ciciliot S, Serrano AL, Argentini C, Kalhovde JM, Lomo T, Schiaffino S (2004) 'NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching'. Proc Natl Acad Sci U S A. (Impact factor 9.4), 20 (101(29)):10590-10595. [Details]|
|Musaro, A., McCullagh, K., Paul, A., Houghton, L., Dobrowolny, G., Molinaro, M., Barton, E.R., Sweeney, H.L. : Rosenthal, N. (2001) 'Localized IGF-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle'. Nature Genetics . (Impact factor 34.3), 27 (2):195-200. [Details]|
|Tsao L, Neville C, Musaro A, McCullagh KJA, Rosenthal N (2000) 'Revisiting calcineurin and human heart failure'. Nature Medicine (Impact factor 27.1), 6 (1):2-3. [Details]|
|Musarò, Antonio, Karl J.A. McCullagh, Frank Naya, Eric N.Olson and Nadia Rosenthal (1999) 'IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1'. Nature (Impact factor 34.5), 400 (6744):581-585. [Details]|
|Baker, S.K., McCullagh, K.J.A., Bonen, A. (1998) 'Training intensity dependent and tissue specific increases in lactate uptake and MCT1 in heart and muscle'. Journal of Applied Physiology, 84 :987-994. [Details]|
|Bonen, A., K. J. A. McCullagh, C. T. Putman, E. Hultman, N. L. Jones, G. J. F. Heigenhauser. (1998) 'Short-term training increases human muscle MCT1 and femoral venous lactate in relation to muscle lactate'. American Journal of Physiology (Endocrinol. Metab.), 274 :E102-E107. [Details]|
|McCullagh, K. J. A., Poole, R. C., Halestrap, A. P., Tipton, K. F., O'Brien, M., : Bonen, A. (1997) 'Chronic electrical stimulation increases MCT1 and lactate uptake in red and white skeletal muscle'. American Journal of Physiology, (Endocrinol. Metab.)(Impact factor: 4.4), 273 :e239-e246. [Details]|
|Johannsson, E.,Nagelhus, E. A., McCullagh, K. J. A., Sejersted, O. M.,Blackstad, T.W.,Bonen, A., : Ottersen, O. P. (1997) 'Cellular and subcellular expression of the monocarboxylate transporter MCT1 in rat heart'. Circulation Research, 80 :400-407. [Details]|
|Handberg, A., Megeney, L. A., McCullagh, K. J. A., Kayser, L. : Bonen, A. (1996) 'Reciprocal GLUT1 and GLUT4 expression and glucose transport in denervated muscles'. American Journal of Physiology (Endocrinol. Metab. 34), 271 :E50-E57. [Details]|
|Johannsson, E., McCullagh, K. J. A., Han, X. X., Fernando, P. K., Jensen, J., Dahl, H. A. : Bonen, A. (1996) 'Effect of overexpressing GLUT-1 and GLUT-4 on insulin- and contraction-stimulated glucose transport in muscle'. American Journal of Physiology (Endocrinol. Metab. 34), 271 :E547-E555. [Details]|
|McCullagh, K. J. A., Juel, C., O'Brien, M. : Bonen, A. ( (1996) 'Chronic muscle stimulation increases lactate transport in rat skeletal muscle'. Molecular Cellular Biochemistry, 156 :51-57. [Details]|
|McCullagh, K. J. A., Poole, R. C., Halestrap, A. P., O'Brien, M. : Bonen, A. (1996) 'The role of the lactate transporter (MCT1) in skeletal muscles'. American Journal of Physiology.(Endocrinol. Metab. 34), 271 :e143-e150. [Details]|
|McCullagh, K. J. A. : Bonen, A. (1995) 'Reduced lactate transport in denervated rat skeletal muscle'. American Journal of Physiology (Reg. Integ. Comp. Physiol. 37), 268 :R884-R888. [Details]|
|McCullagh, K. J. A. : Bonen, A. (1995) 'L(+)-lactate binding to a protein in rat skeletal muscle plasma membranes. '. Canadian Journal of Applied Physiology, 20 :112-124. [Details]|
|Bonen, A. : McCullagh, K. J. A. ( (1994) 'Effects of exercise on lactate transport into mouse skeletal muscles'. Canadian Journal of Applied Physiology, 19 :275-285. [Details]|
|BAHRI OA, WHEATLEY AM, McCULLAGH KJA (2015) Morphometric and capillary analyses of panniculus carnosus skeletal muscle in the mdx mouse 1st NUIG Microcirculation & Angiogenesis Symposium [Details]|
|McCarthy, SD McCullagh, KJA (2013) Gene Therapy for Muscular Dystrophy in an mdx mouse model Royal Academy of Medicine Ireland: Biomedical Science Meeting [Details]|
|McCullagh, KJA (2012) Can a young muscle's stem cell secretome prolong our lives?. Editorial [DOI] [Details]|
|McCarthy, SD,McCullagh, KJA (2013) Gene delivery and targeting nos as therapy for muscular dystrophy. Meeting [Details]|
|Dr Richard Lovering (USA), Dr Karl McCullagh (IRE), Dr. Brent Baker (USA) (2013) Symposium: Functional Outcomes in Skeletal Muscle Disorders: Integrated Biological Evidence. [Invited Oral Presentation], American College of Sports Medicine 60th Annual Meeting & 4th World Congress on Exercise is Medicine, Indianapolis, Indiana, USA , 28-MAY-13 - 01-JUN-13.|