Natural Sciences

     

Peer Reviewed Journals

Rea, S., Eisenhaber, F., O'Carroll, D., Strahl, B. D., Sun, Z. W., Schmid, M., Opravil, S., Mechtler, K., Ponting, C. P., Allis, C. D., and Jenuwein, T. (2000) 'Regulation of chromatin structure by site-specific histone H3 methyltransferases'. Nature, 406 :593-599. [Details]

O'Carroll, D., Scherthan, H., Peters, A. H., Opravil, S., Haynes, A. R., Laible, G., Rea, S., Schmid, M., Lebersorger, A., Jerratsch, M., Sattler, L., Mattei, M. G., Denny, P., Brown, S. D., Schweizer, D., and Jenuwein, T. (2000) 'Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression'. Mol Cell Biol, . [Details]

Lachner, M., O'Carroll, D., Rea, S., Mechtler, K., and Jenuwein, T. (2001) 'Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins'. Nature, 410 :116-120. [Details]

Schotta, G., Ebert, A., Krauss, V., Fischer, A., Hoffmann, J., Rea, S., Jenuwein, T., Dorn, R., and Reuter, G. (2002) 'Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing'. Embo J, . [Details]

Taipale, M., Rea, S., Richter, K., Vilar, A., Lichter, P., Imhof, A., and Akhtar, A. (2005) 'hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells'. Mol Cell Biol, 25 :6798-6810. [Details]

Kubicek, S, O'Sullivan, RJ, August, EM, Hickey, ER, Zhang, Q, Teodoro, ML, Rea, S, Mechtler, K, Kowalski, JA, Homon, CA, Kelly, TA and Jenuwein, T. (2007) 'Reversal of H3K9Me2 by a small molecule inhibitor for the G9a histone methyltransferase'. Mol. Cell, 25 (3):473-481. [Details]

Pfister, S., Rea, S., Taipale M., Mendrzyk, F., Straub, B., Ittrich, C., Thuerigen, O., Sinn, H.P., Lichter, P. and Akhtar, A. (2008) 'The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma'. Int J Can, 122 (6):1207-1213. [Details]

                                                                                                             

Reviews

Rea, S., Akhtar, A., (2006) MSL proteins and the regulation of gene expression. Curr Top Microbiol Immunol. Reviews [Details]

Rea, S., Xouri, G., Akhtar, A., (2007) Males absent on the first MOF: from flies to humans. Oncogene. Reviews [Details]

Chubb JE, Rea S. Subcell Biochem. (2010) Core and linker histone modifications involved in the DNA amage response. Reviews [Details]