Dr Sanjeev Gupta

B.Sc.,M.Sc.,Ph.D

 
researcher
 

Biography

Education

1997- 2002                  Ph.D
                                   Centre for Cellular and Molecular Biology.
                                   Jawaharlal Nehru University, New Delhi, India
                                    Award date: 20 May, 2002

1994- 1996                  Master of Science (M. Sc.) Biochemistry
                                    First class, Hamdard University, New Delhi, India

1991- 1994                  Bachelor of Science (B. Sc.)
                                    First class, Delhi University, Delhi, India

Employment

Post-doctoral fellow                       Kimmel Cancer Center, Thomas Jefferson University
                                                        Philadelphia, USA. 2003 to 2006.

Assistant Professor                         Indian Institute of Technology-Madras (IIT-Madras),
(fixed term)                                     Department of Biotechnology, Chennai, India. 2006-2007.

Senior Researcher                           School of Natural Sciences & NCBES, National University of Ireland,
                                                        Galway, September 2007-2010.                                   

Lecturer                                          School of Medicine, Discipline of Pathology National University of Ireland,                                                        Galway, October 2010-present.

Peer Reviewed Journals

  Year Publication
(2020) 'Differential expression, function and prognostic value of miR-17-92 cluster in ER-positive and triple-negative breast cancer'
Hossain MM;Sultana A;Barua D;Islam MN;Gupta A;Gupta S; (2020) 'Differential expression, function and prognostic value of miR-17-92 cluster in ER-positive and triple-negative breast cancer'. Cancer Treatment And Research Communications, 25 [DOI] [Details]
(2020) 'XBP1 increases transactivation of somatic mutants of ESR1 and loss of XBP1 reverses endocrine resistance conferred by gain-of-function Y537S ESR1 mutation'
Barua D;Abbasi B;Gupta A;Gupta S; (2020) 'XBP1 increases transactivation of somatic mutants of ESR1 and loss of XBP1 reverses endocrine resistance conferred by gain-of-function Y537S ESR1 mutation'. Heliyon, 6 (10) [DOI] [Details]
(2020) 'Targeting the IRE1-XBP1 axis to overcome endocrine resistance in breast cancer: Opportunities and challenges'
Barua D;Gupta A;Gupta S; (2020) 'Targeting the IRE1-XBP1 axis to overcome endocrine resistance in breast cancer: Opportunities and challenges'. Cancer Letters, 486 [DOI] [Details]
(2019) 'Management of Chemotherapy Induced Neutropenia – an Unmet Clinical Need'
Ananya Gupta, Benazir Abbasi, Sanjeev Gupta (2019) 'Management of Chemotherapy Induced Neutropenia – an Unmet Clinical Need'. American Journal Of Clinical Oncology, [DOI] [Details]
(2018) 'Hyperactivation of nuclear receptor coactivators induces PERK-dependent cell death'
Hossain MM;Barua D;Arabkari V;Islam N;Gupta A;Gupta S; (2018) 'Hyperactivation of nuclear receptor coactivators induces PERK-dependent cell death'. Oncotarget, 9 (14) [DOI] [Details]
(2016) 'NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2¿-ATF4 signalling in breast cancer'
Gupta A;Hossain MM;Miller N;Kerin M;Callagy G;Gupta S; (2016) 'NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2¿-ATF4 signalling in breast cancer'. Oncogene, [DOI] [Details]
(2015) 'BCL-2 modulates the unfolded protein response by enhancing splicing of X-box binding protein-1'
Chonghaile TN, Gupta S;John M;Szegezdi E;Logue SE;Samali A (2015) 'BCL-2 modulates the unfolded protein response by enhancing splicing of X-box binding protein-1'. Biochem. Biophys. Res. Commun, 466 (1):40-45 [DOI] [Details]
(2015) 'PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response'
Gupta, A,Hossain, MM,Read, DE,Hetz, C,Samali, A,Gupta, S (2015) 'PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response'. Scientific Reports, 5 [DOI] [Details]
(2015) 'A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy'
Deegan, S,Koryga, I,Glynn, SA,Gupta, S,Gorman, AM,Samali, A (2015) 'A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy'. Biochemical And Biophysical Research Communications, 456 :305-311 [DOI] [Details]
(2014) 'miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts'
Read, DE,Gupta, A,Ladilov, Y,Samali, A,Gupta, S (2014) 'miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts'. Cell And Bioscience, 4 [DOI] [ARAN Link] [Details]
(2014) 'ER stress responses in the absence of apoptosome: A comparative study in CASP9 proficient vs deficient mouse embryonic fibroblasts'
Deegan, S,Saveljeva, S,Gupta, S,MacDonald, DC,Samali, A (2014) 'ER stress responses in the absence of apoptosome: A comparative study in CASP9 proficient vs deficient mouse embryonic fibroblasts'. Biochemical And Biophysical Research Communications, 451 :367-373 [DOI] [Details]
(2014) 'Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions'
Deegan S, Saveljeva S;Logue SE;Pakos-Zebrucka K;Gupta S;Vandenabeele P;Bertrand MJ;Samali A (2014) 'Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions'. Autophagy, 10 (11):1921-1936 [DOI] [Details]
(2013) 'Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim'
Verfaillie T, van Vliet A, Garg AD, Dewaele M, Rubio N, Gupta S, de Witte P, Samali A, Agostinis P (2013) 'Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim'. Biochem, 438 (3):500-506 [DOI] [Details]
(2013) 'Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion'
Cawley K;Logue SE;Gorman AM;Zeng Q;Patterson J;Gupta S;Samali A; (2013) 'Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion'. Plos One, 8 (8) [DOI] [Details]
(2013) 'The eIF2 alpha kinases: their structures and functions'
Donnelly, N,Gorman, AM,Gupta, S,Samali, A (2013) 'The eIF2 alpha kinases: their structures and functions'. Cell Mol Life Sci, 70 :3493-3511 [DOI] [Details]
(2012) 'Bisphenol A-mediated suppression of LPL gene expression inhibits triglyceride accumulation during adipogenic differentiation of human adult stem cells'
Linehan C, Gupta S, Samali A, O'Connor L (2012) 'Bisphenol A-mediated suppression of LPL gene expression inhibits triglyceride accumulation during adipogenic differentiation of human adult stem cells'. Plos One, 7 (5) [DOI] [Details]
(2012) 'Impairment of endoplasmic reticulum in liver as an early consequence of the systemic inflammatory response in rats'
Nurnberger, S,Miller, I,Duvigneau, JC,Kavanagh, ET,Gupta, S,Hartl, RT,Hori, O,Gesslbauer, B,Samali, A,Kungl, A,Redl, H,Kozlov, AV (2012) 'Impairment of endoplasmic reticulum in liver as an early consequence of the systemic inflammatory response in rats'. American Journal Of Physiology-Gastrointestinal And Liver Physiology, 303 :1373-1383 [DOI] [Details]
(2012) 'NOXA contributes to the sensitivity of PERK-deficient cells to ER stress'
Gupta S, Giricz Z, Natoni A, Donnelly N, Deegan S, Szegezdi E, Samali A (2012) 'NOXA contributes to the sensitivity of PERK-deficient cells to ER stress'. Febs Letters, 586 (22):4023-4030 [DOI] [Details]
(2012) 'PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress'
Verfaillie, T,Rubio, N,Garg, AD,Bultynck, G,Rizzuto, R,Decuypere, JP,Piette, J,Linehan, C,Gupta, S,Samali, A,Agostinis, P (2012) 'PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress'. Cell Death And Differentiation, 19 :1880-1891 [DOI] [Details]
(2012) 'Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis'
Gupta, S,Read, DE,Deepti, A,Cawley, K,Gupta, A,Oommen, D,Verfaillie, T,Matus, S,Smith, MA,Mott, JL,Agostinis, P,Hetz, C,Samali, A (2012) 'Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis'. Cell Death & Disease, 3 [DOI] [Details]
(2011) 'Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders'
Doyle KM, Kennedy D, Gorman AM, Gupta S, Healy SJ, Samali A (2011) 'Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders'. Journal Of Cellular And Molecular Medicine, 15 (10):2025-2039 [DOI] [Details]
(2010) 'Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization'
Gupta S;Cuffe L;Szegezdi E;Logue SE;Neary C;Healy S;Samali A; (2010) 'Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization'. International Journal Of Cell Biology, 2010 [DOI] [Details]
(2010) 'HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction'
Gupta S, Deepti A, Deegan S, Lisbona F, Hetz C, Samali A (2010) 'HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction'. Plos Biology, 8 (7) [DOI] [Details]
(2010) 'Methods for monitoring endoplasmic reticulum stress and the unfolded protein response'
Samali A, Fitzgerald U, Deegan S, Gupta S (2010) 'Methods for monitoring endoplasmic reticulum stress and the unfolded protein response'. International Journal Of Cell Biology, 2010 [DOI] [Details]
(2009) 'Bcl-2 family on guard at the ER'
Szegezdi E, Macdonald DC, Ní Chonghaile T, Gupta S, Samali A. (2009) 'Bcl-2 family on guard at the ER'. Am J Physiol Cell Physiol (Epub 2009 Mar 11. Review.PMID: 19279228 [PubMed - indexed for MEDLINE]), 296 (5):941-953 [Details]
(2009) 'Targeting the endoplasmic reticulum-stress response as an anticancer strategy'
Healy, SJM,Gorman, AM,Mousavi-Shafaei, P,Gupta, S,Samali, A (2009) 'Targeting the endoplasmic reticulum-stress response as an anticancer strategy'. European Journal Of Pharmacology, 625 :234-246 [DOI] [Details]
(2009) 'The mitochondrial death pathway: a promising therapeutic target in diseases'
Gupta S;Kass GE;Szegezdi E;Joseph B; (2009) 'The mitochondrial death pathway: a promising therapeutic target in diseases'. Journal Of Cellular And Molecular Medicine, 13 (6) [DOI] [Details]
(2011) 'ASSAYS FOR DETECTING THE UNFOLDED PROTEIN RESPONSE'
Cawley, K;Deegan, S;Samali, A;Gupta, S (2011) 'ASSAYS FOR DETECTING THE UNFOLDED PROTEIN RESPONSE'. Methods In Enzymology: Unfolded Protein Response And Cellular Stress, Vol 490, Pt B, 490 :31-51 [DOI] [Details]
(2012) 'Oestrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'
Gupta, A;Caffrey, E;Callagy, G;Gupta, S (2012) 'Oestrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'. Biochemical Society Transactions, 40 :752-758 [DOI] [Details]
(2013) 'Prognostic Significance of Deregulated Dicer Expression in Breast Cancer'
Caffrey, E;Ingoldsby, H;Wall, D;Webber, M;Dinneen, K;Murillo, LS;Inderhaug, C;Newell, J;Gupta, S;Callagy, G (2013) 'Prognostic Significance of Deregulated Dicer Expression in Breast Cancer'. Plos One, 8 [DOI] [Details]
(2015) 'Assays for Induction of the Unfolded Protein Response and Selective Activation of the Three Major Pathways'
Gupta, A;Read, DE;Gupta, S (2015) 'Assays for Induction of the Unfolded Protein Response and Selective Activation of the Three Major Pathways'. Methods in Molecular Biology, 1292 :19-38 [DOI] [Details]
(2017) 'HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis'
Kennedy, D,Mnich, K,Oommen, D,Chakravarthy, R,Almeida-Souza, L,Krols, M,Saveljeva, S,Doyle, K,Gupta, S,Timmerman, V,Janssens, S,Gorman, AM,Samali, A (2017) 'HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis'. Cell Death & Disease, 8 [DOI] [Details]
(2018) 'Investigation of Anemia and Pie Dielectric Properties of Human Blood at Microwave Frequencies'
Santorelli, A;Abbasi, B;Lyons, M;Hayat, A;Gupta, S;O'Halloran, M;Gupta, A (2018) 'Investigation of Anemia and Pie Dielectric Properties of Human Blood at Microwave Frequencies'. Ieee Access, 6 :56885-56892 [DOI] [Details]
(2012) 'Estrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'
Ananya Gupta, Emer Caffrey, Grace Callagy, Sanjeev Gupta. (2012) 'Estrogen-dependent regulation of miRNA biogenesis: many ways to skin the cat'. Biochemical Society Transactions, [Details]
(2006) 'cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas'
Hu S, Du M-Q, Park S-M, Alcivar A, Qu L, Gupta S, Tang J, Baens M, Ye H, Lee TH, Marynen P, Riley JL, Yang X (2006) 'cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas'. Journal Of Clinical Investigation, [Details]
(2005) 'Role of p73 in regulating human caspase-1 gene transcription induced by interferon-gamma and cisplatin'
Jain N, Gupta S, Sudhakar Ch, Radha V, Swarup G. (2005) 'Role of p73 in regulating human caspase-1 gene transcription induced by interferon-gamma and cisplatin'. Journal Of Biological Chemistry, [Details]
(2005) 'Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis'
Sadasivam S, Gupta S, Radha V, Batta K, Kundu TK, Swarup G (2005) 'Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis'. Oncogene, [Details]
(2004) 'The carboxy terminal tail of Presenilin regulates Omi/HtrA2 protease activity'
Gupta S, Singh R, Datta P, Zhang Z, Orr C, Lu Z, DuBois G, Zervos AS, Meisler MH, Srinivasula SM, Fernandes-Alnemri T, Alnemri ES (2004) 'The carboxy terminal tail of Presenilin regulates Omi/HtrA2 protease activity'. Journal Of Biological Chemistry, [Details]
(2004) 'Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death'
Cilenti L, Soundarapandian MM, Kyriazis GA, Stratico V, Singh S, Gupta S, Bonventre JV, Alnemri ES, Zervos AS (2004) 'Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death'. Journal Of Biological Chemistry, [Details]
(2003) 'Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2'
Srinivasula SM, Gupta S, Datta P, Zhang Z, Hegde R, Cheong N, Fernandes-Alnemri T, Alnemri ES (2003) 'Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2'. Journal Of Biological Chemistry, [Details]
(2003) 'Loss of Omi/HtrA2 protease activity causes neuromuscular disorder in mnd2 mutant mice'
Jones JM, Datta P, Srinivasula SM, Ji W, Gupta S, Zhang Z, Davies E, Hajnóczky G, Saunders TL, Van Keuren ML, Fernandes-Alnemri T, Meisler MH, Alnemri ES. (2003) 'Loss of Omi/HtrA2 protease activity causes neuromuscular disorder in mnd2 mutant mice'. Nature, [Details]
(2002) 'A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis'
Gupta S, Radha V, Sudhakar Ch, Swarup G. (2002) 'A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis'. Febs Letters, [Details]
(2001) 'Direct transcriptional activation of human caspase-1 by tumor suppressor p53'
Gupta S, Radha V, Furukawa Y, Swarup G. (2001) 'Direct transcriptional activation of human caspase-1 by tumor suppressor p53'. Journal Of Biological Chemistry, [Details]
(2001) 'A Nuclear protein tyrosine phosphatase induces shortening of G1 phase and increase in c-myc protein level'
Ganapati U, Gupta S, Radha V, Manogaran PS, Swarup G (2001) 'A Nuclear protein tyrosine phosphatase induces shortening of G1 phase and increase in c-myc protein level'. Experimental Cell Research, [Details]

Book Chapters

  Year Publication
(2015) 'Assays for Induction of the Unfolded Protein Response and Selective Activation of the Three Major Pathways'
Gupta, A,Read, DE,Gupta, S,Oslowski, CM (2015) 'Assays for Induction of the Unfolded Protein Response and Selective Activation of the Three Major Pathways' In: Moethod and Protocols. UK: Elsevier Inc. [DOI] [Details]
(2011) 'ASSAYS FOR DETECTING THE UNFOLDED PROTEIN RESPONSE'
Cawley, K,Deegan, S,Samali, A,Gupta, S (2011) 'ASSAYS FOR DETECTING THE UNFOLDED PROTEIN RESPONSE' In: Methods in enzymology. UK: Elsevier Inc. [DOI] [Details]

Conference Publications

  Year Publication
(2017) San Antonio Breast Cancer Symposium; 2017 Dec 5-9
. MM Hossain, V Arabkari, D Barua, A Gupta, MN Islam and S Gupta (2017) miR-17-92 cluster, an oncogenic microRNA cluster acts as a context dependent tumour suppressor in breast cancer. Cancer Res 2018;78(4 Suppl):Abstract nr P5-07-14 San Antonio Breast Cancer Symposium; 2017 Dec 5-9 [Details]
(2013) 7th Joint Meeting of the British-Division of the Pathology Society
Caffrey, E,Wall, D,Webber, M,Dinneen, K,Ingoldsby, H,Murillo, L,Inderhaug, CR,Newell, J,Gupta, S,Callagy, G (2013) Prognostic Significance of Deregulated Dicer Expression in Breast Cancer. Journal of Pathology. Volume: 231 7th Joint Meeting of the British-Division of the Pathology Society , pp.32-32 [Details]
(2013) 7th Joint Meeting of the British-Division of the Pathology Society
Ingoldsby, H,Caffrey, E,Webber, M,Gupta, S,Callagy, G (2013) Characterisation of Expression of MicroRNAs miR-4726 and miR-4728 in HER2-expressing Breast Cancer. Journal of Pathology.Vol 231 7th Joint Meeting of the British-Division of the Pathology Society , pp.32-32 [Details]
(2010) 8th World Congress on Trauma, Shock, Inflammation and Sepsis
Sanjeev Gupta. (2010) Pathologic impact of ER stress: regulation by Hsp72. Inflammation Research Volume: 59 Pages: S159-S160 8th World Congress on Trauma, Shock, Inflammation and Sepsis [Details]
(2010) 8th World Congress on Trauma, Shock, Inflammation and Sepsis
Nuernberger, S,Gupta, S,Kavanagh, ET,Duvigneau, JC,Miller, I,Hori, O,Samali, A,Redl, H,Kozlov, AV (2010) 9. Ultrastructural changes and underlying molecular mechanisms in rat livers induced by endotoxic shock. Nuernberger, S.; Gupta, S.; Kavanagh, E. T.; et al. Shock Volume: 33 Pages: 79 8th World Congress on Trauma, Shock, Inflammation and Sepsis , pp.79-79 [Details]
(2010) Annual Conference of the Society-for-Glycobiology
Gupta, S; Gerlach, J; Miura, Y; Yamazaki, T; Nakahara, T; Asada, H; Samali, A; Joshi, L. (2010) High Throughput Glycanmap (R) Analysis of Glycosylation during ER Stress and Apoptosis in a Colon Cancer Model.Glycobiology Volume: 20 Issue: 11 Pages: 1471 Annual Conference of the Society-for-Glycobiology [Details]
(2020) American Association for Cancer Research. 2020
D Barua, A Sultana, MN Islam, A Gupta, S Gupta (2020) XBP1 regulates the expression of cell cycle associated genes in ERα positive breast cancer cells. Cancer Research 80 (16 Supplement), 5843-5843 American Association for Cancer Research. 2020 [Details]
(2016) The European Association for Cancer Research is hosting EACR24 in Manchester, UK on July 9-12, 2016
1. Sanjeev Gupta, Ananya Gupta, Muhammad Mosaraf Hossain, Grace Callagy, Michael Kerin (2016) XBP1 modulates luminal breast cancer by transcriptional regulation of SRC-3 during estrogen signaling. European Journal of Cancer 2016; 61 (Supplement 1): S166 The European Association for Cancer Research is hosting EACR24 in Manchester, UK on July 9-12, 2016 [Details]

Other Journals

  Year Publication
(2020) '1. Downregulation of miR-17-92 cluster by PERK fine-tunes unfolded protein response mediated apoptosis'
Danielle E. Read, Ananya Gupta, Karen Cawley, Laura Fontana, Patrizia Agostinis, Afshin Samali, Sanjeev Gupta (2020) '1. Downregulation of miR-17-92 cluster by PERK fine-tunes unfolded protein response mediated apoptosis' BioRxiv, . [DOI] [Details]
(2015) 'Loss of Dicer1 in mouse embryonic fibroblasts impairs ER stress-induced apoptosis'
A Gupta, D Read, D Oommen, A Samali, S Gupta (2015) 'Loss of Dicer1 in mouse embryonic fibroblasts impairs ER stress-induced apoptosis' BioRxiv, . [Details]
(2016) 'Reduced CREB3L2 expression is associated with resistance to sorafenib and poor prognosis in ER-positive breast cancer'
S Mullarkey, V Arabkari, MM Hossain, S Gupta, A Gupta (2016) 'Reduced CREB3L2 expression is associated with resistance to sorafenib and poor prognosis in ER-positive breast cancer' BioRxiv, . [Details]

Conference Contributions

  Year Publication
(2013) BELPSO Meeting,
Logue SE, Deegan S, Saveljeva S, Pakos-Zebrucka K, Gupta S, Vandenabeele P, Bertrand MJ, Samali A. (2013) Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions. [Oral Presentation], BELPSO Meeting, Ghent , 04-APR-13 - 06-APR-13. [Details]
(2011) Annual IAS Meeting 2011- Protein folding and misfolding: mechanisms and consequences,
Sanjeev Gupta (2011) Unfolded Protein Response: Jekyll and Hyde in cancer progression. [Invited Oral Presentation], Annual IAS Meeting 2011- Protein folding and misfolding: mechanisms and consequences, Glenroyal Hotel/National University of Ireland, Ireland , 01-DEC-11 - 03-FEB-12. [Details]
(2011) FASEB SUMMER RESEARCH CONFERENCE:From Unfolded Proteins in the ER to Disease,
Sanjeev Gupta (2011) Perk-dependent Repression of miR-106b-25 Cluster is required for ER stress-induced Apoptosis. [Invited Oral Presentation], FASEB SUMMER RESEARCH CONFERENCE:From Unfolded Proteins in the ER to Disease, VERMONT ACADEMY, Saxtons River, Vermont, USA , 12-JUN-11 - 17-FEB-12. [Details]
(2011) 8th World Congress on Trauma, Shock, Inflammation and Sepsis,
Sanjeev Gupta (2011) Pathologic Impact of ER Stress: regulation by Hsp72. [Invited Oral Presentation], 8th World Congress on Trauma, Shock, Inflammation and Sepsis, Munich/Germany , 09-MAR-11 - 13-MAR-11. [Details]

Reviews

  Year Publication
(2020) Targeting the IRE1-XBP1 axis to overcome endocrine resistance in breast cancer: Opportunities and challenges.
Barua, D;Gupta, A;Gupta, S (2020) Targeting the IRE1-XBP1 axis to overcome endocrine resistance in breast cancer: Opportunities and challenges. CLARE: Reviews [DOI] [Details]
(2009) Bcl-2 family on guard at the ER.
Szegezdi, E;MacDonald, DC;Chonghaile, TN;Gupta, S;Samali, A (2009) Bcl-2 family on guard at the ER. BETHESDA: Reviews [DOI] [Details]
(2009) Targeting the endoplasmic reticulum-stress response as an anticancer strategy.
Healy, SJM;Gorman, AM;Mousavi-Shafaei, P;Gupta, S;Samali, A (2009) Targeting the endoplasmic reticulum-stress response as an anticancer strategy. AMSTERDAM: Reviews [DOI] [Details]
(2009) The mitochondrial death pathway: a promising therapeutic target in diseases.
Gupta, S;Kass, GEN;Szegezdi, E;Joseph, B (2009) The mitochondrial death pathway: a promising therapeutic target in diseases. HOBOKEN: Reviews [DOI] [Details]
(2013) The eIF2 alpha kinases: their structures and functions.
Donnelly, N;Gorman, AM;Gupta, S;Samali, A (2013) The eIF2 alpha kinases: their structures and functions. BASEL: Reviews [DOI] [Details]