Researcher profile

 

Professor Lokesh Joshi

Introducing Lokesh Joshi


Professor Joshi’s research centres on complex sugars (glycans) which are present on every living cell and are key modulators of chemical communication between molecules and cells. Unlike genomics and proteomics, the field of glycomics has lagged behind, primarily because of the complexity of glycans and because of the paucity of simpler and faster analytical technologies. Researchers in Joshi's laboratory are developing biomolecular, imaging and sensor technologies to accelerate the field of glycosciences. These technologies will be applied to a variety of clinical and industrial applications such as chronic and infectious diseases, regenerative biology, protein drug production and bioprocess monitoring.

“Ireland has the momentum and critical mass to become the centre of excellence in this emerging and important field”


As Professor Joshi explains, ”Glycoscience is a truly interdisciplinary field with widespread roles and applications in biomedical science and engineering. Ireland has the momentum and critical mass to become the centre of excellence in this emerging and important field.”

Joshi’s distinguished career


Now living close to the sea in Galway with his wife and two young daughters; Joshi grew up in the desert of India, in the State of Rajasthan, where he completed his Bachelors in chemistry and biology and a Masters degree in zoology.   With a strong curiosity for the natural world, from an early age he wanted to understand the mechanisms controlling complex biological systems. Awarded with a British High Commission Fellowship to study in the UK, Joshi received his PhD in biological sciences at Bath University where he worked on the strategies adopted by pathogenic fungi to colonize the host. Following graduate work, he joined the Boyce Thompson Institute at Cornell University in Ithaca, New York where he completed Post-Doctoral and Research Associate experience in molecular fungal pathology and glycobiology.

An interest in biomedical technology and glycobiology took Joshi to Arizona State University in 2000 where he was appointed Assistant Professor in Life Sciences and then as Associate Professor in the Department of Bioengineering and a member of the Biodesign Institute. There he led a team of researchers working on the glycosylation pathway discovery and engineering and peptide therapeutics to produce biomolecules of therapeutic value.   During this period, Professor Joshi also co-founded a successful biotechnology startup, Arizona Engineered Therapeutics.

In 2005, Joshi was appointed the Interim Director of the Center for Protein and Peptide Therapeutics and then as the Director of the Center for Glycosciences and Technology in the Biodesign Institute at ASU and was active on interdisciplinary research programs for glycotechnology development.

At NUI Galway, Joshi’s lab is comprised of a team made up of experienced and highly capable researchers including four members from Arizona State University; Michelle Kilcoyne, Kausar Nadim Samli, Jared Gerlach and Emily-Joy Farah Samli who are all involved in a wide array of projects for basic glycoscience discovery and the development of next generation glycotechnology tools. Joshi’s team is also collaborating synergistically with existing expertise in Ireland and at NUI Galway, including NCBES and Martin Ryan Institute.

Associate Director of the Centre for BioAnalytical Science

Professor Joshi is also the Associate Director of the Centre for BioAnalytical Science (CBAS) funded by Bristol Myers-Squib (BMS) and IDA Ireland and being coordinated at both Dublin City University (DCU) and NUI Galway. CBAS is a premier example of industrial-government-University partnership in Ireland for developing novel bioanalytical technologies for biopharmaceutical industry.

Lokesh Joshi

Lokesh Joshi