Professor Colm mcDonald

Colm McDonald was appointed Professor of Psychiatry at National University of Ireland, Galway in June 2005 and also holds the post of visiting Professor at the Institute of Psychiatry, King’s College London. A graduate of University College Dublin, he completed his basic clinical training on the St. John of God rotational scheme in psychiatry. In 1998 he moved to the Institute of Psychiatry in London, where he completed his clinical and research training and his PhD. His research centred upon neurobiological abnormalities associated with the major psychotic disorders of schizophrenia and bipolar disorder, and their relationship with genetic liability. His research projects have been supported by the Wellcome Trust, the Medical Research Council, the Royal Society and the National Alliance for Research on Schizophrenia and Depression.

Recent Publications
 

• S.M. O’Brien, E. Devitt, M. Ahmed, C. McDonald (in press) High prevalence of risk factors for physical illness in a long-stay psychiatric unit. Irish Journal of Psychological Medicine

• M. Walshe, M. Taylor, E. Bramon, S. Frangou, K.Schulze, D. Stahl, J. Kravariti, E. Daly, P. Fearon, R.M Murray, C. McDonald (in press). Familial liability to schizophrenia is characterised by impaired academic performance during adolescence. British Journal of Psychiatry

• K.K. Schulze, M.H. Hall, C. McDonald, N. Marshall, M. Walshe, R.M. Murray, E. Bramon (in press). Auditory P300 in patients with bipolar disorder and their unaffected relatives. Bipolar Disorders

• K.K. Schulze, M.H. Hall, C. McDonald, N. Marshall, M. Walshe, R.M. Murray, E. Bramon (in press). P50 auditory evoked potential suppression in bipolar disorder patients with psychotic features and their unaffected relatives. Biological Psychiatry

• D.G. Dikeos, C. Mc Donald, M. Walshe, P.C. Sham, R.M. Murray (2007). Symptom dimensions and the Kraepelinian dichotomy [ltr]. British Journal of Psychiatry 190:361-362

• E.L. Dempster, T. Toulopoulou, C. McDonald, E. Bramon, M. Walshe, H. Wickham, P.C. Sham, R.M. Murray, D.A. Collier (2006). Episodic Memory Performance Predicted by the 2bp Deletion in Exon 6 of the "Alpha 7-Like" Nicotinic Receptor Subunit Gene. American Journal of Psychiatry 163(10):1832-1834.

• D.G.. Dikeos, H. Wickham, C. Mc Donald, M. Walshe, T. Sigmundsson, E. Bramon, A. Grech, R.M. Murray, P.C. Sham (2006). Distribution of symptom dimensions across Kraepelinian divisions. British Journal of Psychiatry 189:346-53

• K. Schulze, J. MacCabe, S. Rabe-Hesketh, T. Crawford, N. Marshall, J. Zanelli, M. Walshe, E. Bramon, R.M. Murray, C. McDonald (2006). The relationship between eye movement and brain structural abnormalities in patients with schizophrenia and their unaffected relatives. Journal of Psychiatry Research 40: 589–598

• C. McDonald, E. Bullmore, R.M. Murray (2006). The Kraepelinian Dichotomy [ltr]. British Journal of Psychiatry 188: 392-393

• C. McDonald, N. Marshall, P. Sham, E.T. Bullmore, K. Schulze, B. Chapple, E. Bramon, F. Filbey, S. Quraishi, M. Walshe, R.M. Murray (2006). Regional brain morphometry in patients with schizophrenia or bipolar disorder and their unaffected relatives. American Journal of Psychiatry 163: 478-487

• E. Bramon, E. Dempster, S. Frangou, C. McDonald, P. Schoenberg, J.H. MacCabe, M. Walshe, P. Sham, D. Collier, R.M. Murray (2006). Is there an association between the COMT gene and P300 endophenotypes? European Psychiatry 21: 70-73

• E. Kravariti, T. Toulopoulou, F. Mapua-Filbey, K. Schulze, M. Walshe, P. Sham, R.M. Murray, C. McDonald (2006). Intellectual asymmetry and genetic liability in first-degree relatives of probands with schizophrenia. British Journal of Psychiatry, 188:186-7

• T. Toulopoulou, S. Quraishi, C. McDonald, R.M. Murray (2006) The Maudsley Family Study: Premorbid and current general intellectual function levels in familial bipolar I disorder and schizophrenia. Journal of Clinical and Experimental Neuropsychology, 28(2): 243-59

• C. McDonald, K. Schulze, R. Murray, M. Tohen (Eds). Bipolar Disorder: The Upswing in Research and Treatment. Martin Dunitz, London, 2005.

• J. MacCabe, H. Simon, R. Walwyn, C. McDonald, R. Murray (2005). Saccadic distractibility is elevated in schizophrenic patients, but not in their well relatives. Psychological Medicine, 35(12):1727-36

• E. Bramon, C. McDonald, R.J. Croft, J.H. Gruzelier, S. Landau, P.C. Sham, S. Frangou, R.M. Murray (2005). Is the P300 wave an endophenotype for schizophrenia? A meta-analysis and a family study. Neuroimage, 27(4):960-8

• F.V. Rijsdijk, N.E.M. vanHaren, M. Picchioni, C. McDonald, N. Davies, T. Sharma, H.E. Hulshoff Pol, R.S. Kahn, R. Murray, P.C. Sham (2005). Brain MRI Abnormalities in Schizophrenia: Same Genes or Same Environment? Psychological Medicine, 35(10):1399-409

• J. Zanelli, H. Simon, S. Rabe-Hesketh, M. Walshe, C. McDonald, R.M. Murray, J.H. MacCabe (2005). Eye tracking in schizophrenia: does the antisaccade task measure anything that the smooth pursuit task does not? Psychiatry Research,136(2-3):181-8

• T. Toulopoulou, F. Mapua-Filbey, S. Quraishi , E. Kravariti, R.G. Morris, C. McDonald, M. Walshe, E. Bramon, R.M. Murray (2005). Cognitive performance in presumed obligate carriers for psychosis. British Journal of Psychiatry, 187: 284-285.

• C. McDonald, E. Bullmore, P. Sham, X. Chitnis, J. Suckling, J. MacCabe, M. Walshe, R. Murray (2005). Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder: a computational morphometry study. British Journal of Psychiatry, 186: 369-77

• E. Bramon, M. Walshe, C. McDonald, B. Martin, T. Toulopoulou, H. Wickham, J. van Os, P. Fearon, P. Sham, L. Fañanás, R. Murray (2005). Dermatoglyphics and Schizophrenia: A meta-analysis investigation of the impact of obstetric complications upon a–b ridge count. Schizophrenia Research, 75: 399-404

• E. Dempster, T. Toulopoulou, C. McDonald, E. Bramon, M. Walshe, F. Mapua-Filbey, H. Wickham, P.C. Sham, R.M. Murray, D.A. Collier (2005). Association between BDNF val66met genotype and episodic memory. American Journal of Medical Genetics B Neuropsychiatric Genetics, 134 (1):73-5

• M. Walshe, C. McDonald, M. Taylor, J. Zhao, P. Sham, A. Grech, K. Schulze, E. Bramon, R.M. Murray (2005). Obstetric Complications In Patients With Schizophrenia And Their Unaffected Siblings. European Psychiatry, 20:28-34

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