Congratulations to Dr Sean Hynes who recently won the Royal Academy of Medicine in Ireland (RAMI) Pathology Registrar's medal. The medal was presented to Dr Hynes at the Royal College of Physicians of Ireland in Kildare Street, Dublin for his previous work at REMEDI on gene therapy versus stem cell therapy in vascular remodelling. The prize was presented by Dr. Christian Gulmann, President of the Pathology Section in RAMI.
Gene-eluting stents: non-viral, liposome-based gene delivery of eNOS to the blood vessel wall in vivo results in enhanced endothelialization but does not reduce restenosis in a hypercholesterolemic model. Sharif F, Hynes SO, McCullagh KJ, Ganley S, Greiser U, McHugh P, Crowley J, Barry F, O'Brien T. Gene Ther. 2011 Jun 30.
β cell protection by inhibition of iNOS through lentiviral vector-based strategies. Hynes SO, McCabe C, O'Brien T. Methods Mol Biol. 2011;704:153-68.
Bolus delivery of mesenchymal stem cells to injured vasculature in the rabbit carotid artery produces a dysfunctional endothelium. O'Shea CA, Hynes SO, Shaw G, Coen BA, Hynes AC, McMahon J, Murphy M, Barry F, O'Brien T. Tissue Eng Part A. 2010 May;16(5):1657-65.
Gene-eluting stents: adenovirus-mediated delivery of eNOS to the blood vessel wall accelerates re-endothelialization and inhibits restenosis. Sharif F, Hynes SO, Cooney R, Howard L, McMahon J, Daly K, Crowley J, Barry F, O'Brien T. Mol Ther. 2008 Oct;16(10):1674-80. Epub 2008 Aug 19.