Examination of the neonatal immune response. We explore how adult derived stem cells can be transplanted even when mismatched (allogeneic transplantation).
The immunologic profile of allogenic differentiated MSCs for therapeutic applications, Immunology & Cancer cell biology, Immunology & Mechanisms of colon cancer metastasis
The main goal of Claas's project is to determine the relationship between differentiation potential and immune modulatory function in clonally-selected MSCs of mouse and human.
Bairbre's research is focusing on diabetic kidney disease (diabetic nephrology), in particular looking at approaches used in vivo animal and human studies.
Mouse lymphocyte development, with specific interest in the role of Interleukin-7. Determination of the process of lineage commitment in haematopoiesis
Lisa's project is focusing on the generation of tolerogenic bone marrow derived dendritic cells by gene therapy and chemical modification, for the application in allogeneic transplantation.