Fáilte chuig an Institiúid um Leigheas Athghiniúnach
Welcome to the Regenerative Medicine Institute (REMEDI®)

Production

Researcher in

Research Project Area: 

Production and Process Optimisation of hMSCs in a GMP facility.

Currently working towards the establishment of a GMP licensed facility for the manufacture of hMSC for Phase I and II human clinical trials. Involved in process optimisation, development of QC assays and validation protocols as well as documentation of all processes.

Positions Held: 

2010-present
Production, CCMI

2002-2010
Senior Technical Officer
REMEDI

2004-2005
Higher Diploma in Quality Assurance
N.U.I.G
‘Sourcing materials and compiling documentation for a cGMP facility’.

2001-2002
Masters in Molecular Medicine
Trinity College Dublin
‘The Role of PPAR Gamma and Fatty Acids in Colon Cancer’.
 

Awards & Honours: 

June 2004
Awarded a Maire Curie Fellowship to attend Vecteurotrain Course and Conference in Evry, Paris, France

October 2006
Completed and passed the Cleanroom Testing and Certification Board (CTCB) course and exam in Cleanroom Technology October 2006. This is an accredited exam by the International Confederation of Contamination Control Societies (ICCCS).

 

Selected Publications: 

Duffy A, Liew A, O'Sullivan J, Avalos G, Samali A, O'Brien T.
Distinct effects of high-glucose conditions on endothelial cells of macrovascular and microvascular origins. Endothelium. 2006 Jan-Feb;13(1):9-16.

Duffy AM, O'Doherty AM, O'Brien T, Strappe PM.
Purification of adenovirus and adeno-associated virus: comparison of novel membrane-based technology to conventional techniques.
Gene Therapy. 2005 Oct;12 Suppl 1:S62-72.

Cooney R, Hynes SO, Duffy AM, Sharif F, O'Brien T.
Adenoviral-mediated gene transfer of nitric oxide synthase isoforms and vascular cell proliferation. Journal of Vascular Research. 2006;43(5):462-72. Epub 2006 Aug 17