Stem Cells in Cardiovascular disease
Researcher in
At present, there is no clinical therapy available for the repair of damaged cardiac muscle, thereby presenting tremendous opportunities for the creation of novel nanotechnology based therapies. To date, very little is known about the effects of carbon nanotubes (CNT) on stem cell differentiation, especially, mesenchymal stem cells (MSC). Since CNT are electrically conductive, this offers huge potential for the manipulation of MSC differentiation pathways to create electroactive cells such as those found in the heart. This project involves the study of various methods of manipulating MSC to repair the injured heart.
2005 - Present Postdoctoral Researcher, REMEDI, NUI, Galway
2004 - 2005 M.Sc in Biomedical Science, National University of Ireland, Galway
2000 - 2004 B.Sc in Biotechnology, National University of Ireland, Galway
2005 National University of Ireland Science Faculty Fellowship
PubMed Link: http://www.ncbi.nlm.nih.gov/pubmed?term=Mooney%20E%20Galway
Publications
Mooney E, Dockery P, Greiser U, Murphy M, Barron V. Carbon nanotubes and mesenchymal stem cells: biocompatibility, proliferation and differentiation. Nano Lett. 2008 Aug;8(8):2137-43. Epub 2008 Jul 12. PMID:18624387
Conference/Talks
Carbon Nanotubes and Mesenchymal Stem Cells: Biocompatibility, Proliferation and Differentiation, Nanoletters Journal, June 2008
Induction of differention of Mesenchmal Stem Cells to a Cardiomyocyte Phenotype by different stimuli, ISSCR, Cairns, June 2007
Differentiation of human Mesenchymal Stem Cells to a cardiomyocyte phenotype in response to growth factors, ISCT Sydney, June 2007
Differentiation of Mesenchymal Stem Cells towards a cardiomyocytes phenotype, ISCGT, REMEDI - NUI Galway, May 2007
Differentiation of human Mesenchymal Stem Cells to a cardiomyocyte phenotype in response to growth factors, ESF-Barcelona, October 2006
