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Welcome to the Regenerative Medicine Institute (REMEDI®)

Dr. Faisal Sharif


Senior Lecturer in Regenerative Medicine

His key area of interest is translational medicine focusing on cardiovascular clinical trials for medical devices and basic science outputs.

Researcher in

Research Project Area: 

For basic research, his interest lays in vascular biology and myocardial regeneration. At the basic science level his interest lies in myocardial regeneration and vascular biology. His research will focus on Induced Pluripotent Stem Cells (IPS) for myocardial homing, engraftment and regeneration. He will also continue to pursue research on vascular wall healing post-stenting through development of novel techniques and devices.

Positions Held: 

October 2010 - Present  Senior Lecturer in Regenerative Medicine, NUI Galway & Consultant Cardiologist, Galway University Hospital 

October 2009 - September 2010   Research Fellow in Interventional Cardiology, OLV Ziekenhuis Cardiovascular Centre, Aalst, Belgium

November 2006 - December 2007  Research Fellow in Interventional Cardiology, Department of Cardiology, Clinique Pasteur, Toulouse, France & St. James' Hospital, Dublin

June 2003 - June 2006  Ph.D in Vascular Biology and Gene Eluting Stents, REMEDI, NUI Galway

July 2002 - June 2003  Specialist Registrar in General Medicine,  Mayo General Hospital

July 2000-June 2000  Specialist Registrar in Cardiology, Galway Regional Hospital 

Selected Publications: 

Sharif F, Bartunek J, Vanderheyden M. Adult stem cells in the treatment of acute myocardial infarction. Catheter Cardiovasc Interv. 2011 Jan 1;77(1):72-83. doi: 10.1002/ccd.22620.

Puymirat É, Muller O, Sharif F, Dupouy P, Cuisset T, de Bruyne B, Gilard M. Fractional flow reserve: concepts, applications and use in France in 2010.  Arch Cardiovasc Dis. 2010 Nov-Dec;103(11-12):615-22. Epub 2010 Nov 25.

Sharif F, Trana C, Muller O, De Bruyne B.  Practical tips and tricks for the measurement of fractional flow reserve. Catheter Cardiovasc Interv. 2010 Dec 1;76(7):978-85. doi: 10.1002/ccd.22603.

Impact of Atherosclerotic Disease Progression on Mid-Term Clinical Outcome in Diabetic Patients in the Drug-Eluting Stent Era
P Tousek, A Pavei, J Oreglia, G Martin, F Sharif, J Fajadet, B Farah  EuroIntervention. 2009 Mar;4(5):588-92

Long-term Follow-up of Percutaneous Coronary Intervention of Unprotected Left Main Lesions with Drug Eluting Stents: Predictors of Clinical Outcome
A Pavei, J Oreglia, G Martin, P Tousek, F Sharif, B Farah, A Sauguet, J Fajadet
EuroIntervention. 2009 Jan; 4(4): 457-63

Gene Eluting Stents: Delivery of Adenovirus Mediated Endothelial Nitric Oxide Synthase to the Blood Vessel Wall Accelerates Re-endothelialization and Inhibits Restenosis in Rabbit Iliac Arteries
F Sharif, S Hynes, R Cooney, L Howard, J McMahon, K Daly, J Crowley, T O’Brien
Mol Ther. 2008 Oct; 16(10):1674-80

Connolley T, Nash D, Buffière JY, Sharif F, McHugh PE.  X ray micro-tomography of a coronary stent deployed in a model artery. Med Eng Phys. 2007 Dec;29(10):1132-41. Epub 2006 Nov 29.

Gene Eluting Stents: A Comparison of Adenoviral and Adeno-Associated Viral Gene-Delivery to the Blood Vessel Wall in vivo
F Sharif, S Hynes, J McMahon, R. Cooney, S. Conroy, P. Dockery, G. Duffy, K.Daly, J. Crowley, J S. Bartlett, T. O’Brien
Hum Gene Ther 2006 Jul; 17(7):741-50

Adenoviral-Mediated Gene Transfer of Nitric Oxide Synthase Isoforms and Vascular Cell Proliferation
R Cooney, S Hynes, F Sharif, T O’Brien
J Vasc Res 2006; 43(5):462-72

Effect of gene delivery of NOS isoforms on intimal hyperplasia and endothelial regeneration after balloon injury.
R. Cooney, S. Hynes, F Sharif, T O’Brien
Gene Ther. 2007 Mar; 14 (5):396-404

Review Articles

Practical Tips and Tricks for the Measurement of Fractional    Flow Reserve.
F Sharif, Catalina Trana, Olivier Muller, Bernard De Bryune
Catheterization and Cardiovascular Interventions In Press

Adult stem Cells in the Treatment of Acute Myocardial Infarction.
F Sharif, Jozef Bartunek, Marc Vanderheyden
Catheterization and Cardiovascular Interventions In Press

Current Status of Vulnerable Plaque Detection.
F Sharif, R. T Murphy
Catheterization and Cardiovascular Interventions 75:135-144(2010)

Current Status of Catheter and Stent-Based Gene Therapy.
F Sharif, K Daly, J Crowley, T O’Brien
Cardiovascular Research 64(2004)208-216

Book Chapters

 Unprotected Left Main Stenting Using Trans Radial Approach
Faisal Sharif, Bruno Farah, Jean Fajadet (Chapter 16)

Transradial Approach for Cardiovascular Interventions
A Book by Martial Hamon and Eugene McFadden

Professional and Personal Interests: 

Professional Memberships

• Irish Cardiac Society
• European Society of Cardiology
• British Cardiovascular and Interventional Society
• European Association of Percutaneous Corornary Intervention
• Fellowship of the European Society of Cardiology

Search PubMed for Papers by Dr. Faisal Sharif >>