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About NUI Galway
About NUI Galway
Since 1845, NUI Galway has been sharing the highest quality teaching and research with Ireland and the world. Find out what makes our University so special – from our distinguished history to the latest news and campus developments.
Colleges & Schools
Colleges & Schools
NUI Galway has earned international recognition as a research-led university with a commitment to top quality teaching across a range of key areas of expertise.
- Research & Innovation
- Business & Industry
- Alumni, Friends & Supporters
At NUI Galway, we believe that the best learning takes place when you apply what you learn in a real world context. That's why many of our courses include work placements or community projects.
Dr MIRIAM O'DUILL
School of Chemistry
T: +353 91 493120
2011 – 2015 D.Phil. in Organic Chemistry, Prof. Veronique Gouverneur, University of Oxford
2007 – 2011 Master of Chemistry (M.Chem.), Merton College, University of Oxford
Deuteration of bioactive molecules is a crucial tool for biomolecular analysis techniques (neutron diffraction, 2D NMR, hydrogen exchange mass spectroscopy) and the pharmaceutical industry (ADME studies, deuterated drugs). A diverse toolkit of synthetic methods is necessary to selectively install deuterium isotopes in the molecules and positions of interest.
Super-electrophilic alkylating reagents: The development of less hazardous, more reactive alternatives to complement and extend the reactivity of currently known alkylating agents—especially for application in medicinal chemistry—is an exciting challenge.
Design and synthesis of polymeric drug delivery systems in collaboration with CURAM.
Our group’s goal is to address these challenges using catalytic methods. The interdisciplinary nature of our research projects would allow students to gain experience in synthetic organic, physical organic, organometallic, and fluorine chemistry, as well as related disciplines in and outside of chemistry.
Group website: https://oduillgroup.com/
Peer Reviewed Journals
|(2017)|| 'Tridentate Directing Groups Stabilize 6-Membered Palladacycles in Catalytic Alkene Hydrofunctionalization'
Miriam L. O’Duill, Rei Matsuura, Yanyan Wang, Joshua L. Turnbull, John A. Gurak Jr., De-Wei Gao, Gang Lu, Peng Liu, Keary M. Engle (2017) 'Tridentate Directing Groups Stabilize 6-Membered Palladacycles in Catalytic Alkene Hydrofunctionalization'. Journal Of The American Chemical Society, 139 (44):15576-15579 [DOI] [Details]
|(2017)|| 'Palladium(II)-Catalyzed Directed anti-Hydrochlorination of Unactivated Alkynes with HCl'
Joseph Derosa, Annabelle L. Cantu, Mark N. Boulous, Miriam L. O’Duill, Joshua L. Turnbull, Zhen Liu, Daizy M. De La Torre, Keary M. Engle (2017) 'Palladium(II)-Catalyzed Directed anti-Hydrochlorination of Unactivated Alkynes with HCl'. Journal Of The American Chemical Society, 139 (14):5183-5193 [DOI] [Details]
|(2015)|| 'Recruitment and Immobilization of a Fluorinated Biomarker Across an Interfacial Phospholipid Film using a Fluorocarbon Gas'
Yang, G;O'Duill, M;Gouverneur, V;Krafft, MP (2015) 'Recruitment and Immobilization of a Fluorinated Biomarker Across an Interfacial Phospholipid Film using a Fluorocarbon Gas'. Angewandte Chemie (International ed. in English), 54 :8402-8406 [DOI] [Details]
|(2015)|| 'Cross-Coupling of [2-Aryl-1,1,2,2-tetrafluoroethyl](trimethyl)silanes with Aryl Halides'
O'Duill, M;Dubost, E;Pfeifer, L;Gouverneur, V (2015) 'Cross-Coupling of [2-Aryl-1,1,2,2-tetrafluoroethyl](trimethyl)silanes with Aryl Halides'. Organic Letters, 17 :3466-3469 [DOI] [Details]
|(2013)|| 'Catalytic Hydrotrifluoromethylation of Unactivated Alkenes'
Mizuta, S;Verhoog, S;Engle, KM;Khotavivattana, T;O'Duill, M;Wheelhouse, K;Rassias, G;Medebielle, M;Gouverneur, V (2013) 'Catalytic Hydrotrifluoromethylation of Unactivated Alkenes'. Journal Of The American Chemical Society, 135 :2505-2508 [DOI] [Details]
|(2013)|| 'Trifluoromethylation of Allylsilanes under Photoredox Catalysis'
Mizuta, S;Engle, KM;Verhoog, S;Galicia-Lopez, O;O'Duill, M;Medebielle, M;Wheelhouse, K;Rassias, G;Thompson, AL;Gouverneur, V (2013) 'Trifluoromethylation of Allylsilanes under Photoredox Catalysis'. Organic Letters, 15 :1250-1253 [DOI] [Details]
|(2013)|| 'Catalytic Decarboxylative Fluorination for the Synthesis of Tri- and Difluoromethyl Arenes'
Mizuta, S;Stenhagen, ISR;O'Duill, M;Wolstenhulme, J;Kirjavainen, AK;Forsback, SJ;Tredwell, M;Sandford, G;Moore, PR;Huiban, M;Luthra, SK;Passchier, J;Solin, O;Gouverneur, V (2013) 'Catalytic Decarboxylative Fluorination for the Synthesis of Tri- and Difluoromethyl Arenes'. Organic Letters, 15 :2648-2651 [DOI] [Details]
Honours and Awards
|2018||RSC Researcher Mobility Grant||Royal Society of Chemistry|
|2017||SoF Travel Award||The Scripps Research Institute|
|2016||3rd Prize SoF Lightning Talk Competition||The Scripps Research Institute|
|2015||Postdoctoral Fellowship||DAAD (German Academic Exchange Service)|
|2013||Eli Lilly Prize for Excellence in Organic Chemistry||Eli Lilly|
|2011||BBSRC DTC Scholarship in Molecular Biochemistry and Chemical Biology||BBSRC|
|2010||Systems Approaches to Biomedical Sciences Industrial Doctorate Scholarship (declined)||University of Oxford|
|2010||Exhibitioner Scholarship||Merton College, Oxford|
|2010||Postmaster Scholarship||Merton College, Oxford|
|2007||BCCG Foundation Award||British Chamber of Commerce in Germany|
|2007||Undergraduate Scholarship||Studienstiftung des deutschen Volkes|
|Association||Function||From / To|
|Royal Society of Chemistry||Associate Member||/|
|Employer||Position||From / To|
|The Scripps Research Institute||Postdoctoral Research Fellow||25-JAN-16 / 15-DEC-17|
|2011||University of Oxford||Master of Chemistry (M.Chem.)||Chemistry|
|2015||University of Oxford||PhD||Chemistry|
|Term/Year||Module Title||Module Code||Subject / Desc|
|2018/19||Organic & Bioorganic Chemistry - Radicals, Polymers and Supramolecular Chemistry||CH4104|
|2018/19||Organic Chemistry - Heterocyclic Chemistry||CH311|
|2018/19||Analytical & Biophysical Chemistry - Introduction to Medical Imaging||CH4107|
|2018/19||Synthesis, Organometallic & Analytical Chemistry - Introduction to Medical Imaging||CH4102|