Dr Derek Morris

BSc, Ph.D

Contact Details

Lecturer In Biomedical Science
Biochemistry
Room 106
Discipline of Biochemistry
Arts/Science Building
NUI Galway
Ireland

T: +353 91 494439
E: derek.morris@nuigalway.ie
W: http://www.nuigalway.ie/nicog/
Lecturer Above The Bar
Biomedical Science
Biochemistry
School of Natural Sciences
NUI Galway

E: DEREK.MORRIS@nuigalway.ie
 
researcher

Biography

Derek Morris graduated with a B.Sc. in Biotechnology from the National University of Ireland, Galway in 1998. In 2001, he completed his PhD in molecular genetics at the Department of Psychological Medicine, Cardiff University. He subsequently joined the Neuropsychiatric Genetics Research Group in Trinity College Dublin as a research fellow and was awarded a HRB Postdoctoral Career Development Research Fellowship in 2003. In 2006, Dr. Morris was appointed Lecturer in Molecular Psychiatry within the Discipline of Psychiatry in TCD and in 2013 moved to NUI Galway where he is now Lecturer in Biomedical Science within the Discipline of Biochemistry. Dr. Morris’ research interests are the development of novel methods for mapping genes for complex diseases and the application of high-throughput genomics technologies to the detection of risk genes for schizophrenia and bipolar disorder. He has extensive experience of genome-wide association studies (GWAS) and using SFI funding, set up TrinSeq, the first next-generation sequencing lab in Ireland in 2008. Since moving to NUI Galway in late 2013, Dr. Morris has established, is a PI and leads the genetics studies with the Centre for Neuroimaging and Cognitive Genomics (NICOG). His research activity within NICOG focuses on epigenetic regulation of gene expression as a risk mechanisms for schizophrenia. He also coordinates study design and the management of biosample resources and genetics data used for ongoing studies. Dr. Morris is a former President of the Irish Society of Human Genetics (2014-16).

Peer Reviewed Journals

  Year Publication
(2016) 'Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness'
Bigdeli TB;Ripke S;Bacanu SA;Lee SH;Wray NR;Gejman PV;Rietschel M;Cichon S;St Clair D;Corvin A;Kirov G;McQuillin A;Gurling H;Rujescu D;Andreassen OA;Werge T;Blackwood DH;Pato CN;Pato MT;Malhotra AK;O'Donovan MC;Kendler KS;Fanous AH; Schizophrenia Working Group of the Psychiatric Genomics Consortium (2016) 'Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness'. American Journal Of Medical Genetics. Part B: Neuropsychiatric Genetics, 171B (2):276-289 [Details]
(2016) 'Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex'
Guadalupe T;Mathias SR;vanErp TG;Whelan CD;Zwiers MP;Abe Y;Abramovic L;Agartz I;Andreassen OA;Arias-Vásquez A;Aribisala BS;Armstrong NJ;Arolt V;Artiges E;Ayesa-Arriola R;Baboyan VG;Banaschewski T;Barker G;Bastin ME;Baune BT;Blangero J;Bokde AL;Boedhoe PS;Bose A;Brem S;Brodaty H;Bromberg U;Brooks S;Büchel C;Buitelaar J;Calhoun VD;Cannon DM;Cattrell A;Cheng Y;Conrod PJ;Conzelmann A;Corvin A;Crespo-Facorro B;Crivello F;Dannlowski U;de Zubicaray GI;de Zwarte SM;Deary IJ;Desrivières S;Doan NT;Donohoe G;Dørum ES;Ehrlich S;Espeseth T;Fernández G;Flor H;Fouche JP;Frouin V;Fukunaga M;Gallinat J;Garavan H;Gill M;Suarez AG;Gowland P;Grabe HJ;Grotegerd D;Gruber O;Hagenaars S;Hashimoto R;Hauser TU;Heinz A;Hibar DP;Hoekstra PJ;Hoogman M;Howells FM;Hu H;Hulshoff Pol HE;Huyser C;Ittermann B;Jahanshad N;Jönsson EG;Jurk S;Kahn RS;Kelly S;Kraemer B;Kugel H;Kwon JS;Lemaitre H;Lesch KP;Lochner C;Luciano M;Marquand AF;Martin NG;Martínez-Zalacaín I;Martinot JL;Mataix-Cols D;Mather K;McDonald C;McMahon KL;Medland SE;Menchón JM;Morris DW;Mothersill O;Maniega SM;Mwangi B;Nakamae T;Nakao T;Narayanaswaamy JC;Nees F;Nordvik JE;Onnink AM;Opel N;Ophoff R;Paillère Martinot ML;Papadopoulos Orfanos D;Pauli P;Paus T;Poustka L;Reddy JY;Renteria ME;Roiz-Santiáñez R;Roos A;Royle NA;Sachdev P;Sánchez-Juan P;Schmaal L;Schumann G;Shumskaya E;Smolka MN;Soares JC;Soriano-Mas C;Stein DJ;Strike LT;Toro R;Turner JA;Tzourio-Mazoyer N;Uhlmann A;Hernández MV;van den Heuvel OA;van der Meer D;van Haren NE;Veltman DJ;Venkatasubramanian G;Vetter NC;Vuletic D;Walitza S;Walter H;Walton E;Wang Z;Wardlaw J;Wen W;Westlye LT;Whelan R;Wittfeld K;Wolfers T;Wright MJ;Xu J;Xu X;Yun JY;Zhao J;Franke B;Thompson PM;Glahn DC;Mazoyer B;Fisher SE;Francks C (2016) 'Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex'. Brain Imaging And Behavior, [Details]
(2017) 'Occurrence and co-occurrence of hallucinations by modality in schizophrenia-spectrum disorders'
McCarthy-Jones S;Smailes D;Corvin A;Gill M;Morris DW;Dinan TG;Murphy KC;Anthony O Neill F;Waddington JL;Australian Schizophrenia Research Bank;Donohoe G;Dudley R (2017) 'Occurrence and co-occurrence of hallucinations by modality in schizophrenia-spectrum disorders'. Psychiatry Research, 252 :154-160 [DOI] [Details]
(2017) 'Further evidence of alerted default network connectivity and association with theory of mind ability in schizophrenia'
Mothersill O;Tangney N;Morris DW;McCarthy H;Frodl T;Gill M;Corvin A;Donohoe G (2017) 'Further evidence of alerted default network connectivity and association with theory of mind ability in schizophrenia'. Schizophrenia Research, 184 :52-58 [DOI] [Details]
(2015) 'MIR137HG risk variant rs1625579 genotype is related to corpus callosum volume in schizophrenia'
Patel VS;Kelly S;Wright C;Gupta CN;Arias-Vasquez A;Perrone-Bizzozero N;Ehrlich S;Wang L;Bustillo JR;Morris D;Corvin A;Cannon DM;McDonald C;Donohoe G;Calhoun VD;Turner JA; (2015) 'MIR137HG risk variant rs1625579 genotype is related to corpus callosum volume in schizophrenia'. Neuroscience Letters, 602 :44-49 [DOI] [Details]
(2015) 'New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis'
Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, Zhao Q, Kendler KS, Sullivan PF, Price AL, O'Donovan M, Okada Y, Mowry BJ, Raychaudhuri S, Wray NR; Schizophrenia Working Group of the Psychiatric Genomics Consortium and Rheumatoid Arthritis Consortium International; Schizophrenia Working Group of the Psychiatric Genomics Consortium authors, Byerley W, Cahn W, Cantor RM, Cichon S, Cormican P, Curtis D, Djurovic S, Escott-Price V, Gejman PV, Georgieva L, Giegling I, Hansen TF, Ingason A, Kim Y, Konte B, Lee PH, McIntosh A, McQuillin A, Morris DW, Nöthen MM, O'Dushlaine C, Olincy A, Olsen L, Pato CN, Pato MT, Pickard BS, Posthuma D, Rasmussen HB, Rietschel M, Rujescu D, Schulze TG, Silverman JM, Thirumalai S, Werge T; Schizophrenia Working Group of the Psychiatric Genomics Consortium collaborators, Agartz I, Amin F, Azevedo MH, Bass N, Black DW, Blackwood DH, Bruggeman R, Buccola NG, Choudhury K, Cloninger RC, Corvin A, Craddock N, Daly MJ, Datta S, Donohoe GJ, Duan J, Dudbridge F, Fanous A, Freedman R, Freimer NB, Friedl M, Gill M, Gurling H, De Haan L, Hamshere ML, Hartmann AM, Holmans PA, Kahn RS, Keller MC, Kenny E, Kirov GK, Krabbendam L, Krasucki R, Lawrence J, Lencz T, Levinson DF, Lieberman JA, Lin DY, Linszen DH, Magnusson PK, Maier W, Malhotra AK, Mattheisen M, Mattingsdal M, McCarroll SA, Medeiros H, Melle I, Milanova V, Myin-Germeys I, Neale BM, Ophoff RA, Owen MJ, Pimm J, Purcell SM, Puri V, Quested DJ, Rossin L, Ruderfer D, Sanders AR, Shi J, Sklar P, St Clair D, Scott Stroup T, Van Os J, Visscher PM, Wiersma D, Zammit S; Rheumatoid Arthritis Consortium International authors, Louis Bridges S Jr, Choi HK, Coenen MJ, de Vries N, Dieud P, Greenberg JD, Huizinga TW, Padyukov L, Siminovitch KA, Tak PP, Worthington J; Rheumatoid Arthritis Consortium International collaborators, De Jager PL, Denny JC, Gregersen PK, Klareskog L, Mariette X, Plenge RM, van Laar M, van Riel P. (2015) 'New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis'. International Journal Of Epidemiology, [Details]
(2015) 'Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis'
Bowes, J,Budu-Aggrey, A,Huffmeier, U,Uebe, S,Steel, K,Hebert, HL,Wallace, C,Massey, J,Bruce, IN,Bluett, J,Feletar, M,Morgan, AW,Marzo-Ortega, H,Donohoe, G,Morris, DW,Helliwell, P,Ryan, AW,Kane, D,Warren, RB,Korendowych, E,Alenius, GM,Giardina, E,Packham, J,McManus, R,FitzGerald, O,McHugh, N,Brown, MA,Ho, P,Behrens, F,Burkhardt, H,Reis, A,Barton, A (2015) 'Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis'. Nature Communications, 6 [DOI] [Details]
(2015) 'Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms'
Baurecht, H,Hotze, M,Brand, S,Buning, C,Cormican, P,Corvin, A,Ellinghaus, D,Ellinghaus, E,Esparza-Gordillo, J,Folster-Holst, R,Franke, A,Gieger, C,Hubner, N,Illig, T,Irvine, AD,Kabesch, M,Lee, YAE,Lieb, W,Marenholz, I,McLean, WHI,Morris, DW,Mrowietz, U,Nair, R,Nothen, MM,Novak, N,O'Regan, GM,Schreiber, S,Smith, C,Strauch, K,Stuart, PE,Trembath, R,Tsoi, LC,Weichenthal, M,Barker, J,Elder, JT,Weidinger, S,Cordell, HJ,Brown, SJ,PAGE Consortium (2015) 'Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms'. American Journal Of Human Genetics, 96 :104-120 [DOI] [Details]
(2015) 'Common genetic variants influence human subcortical brain structures'
Hibar DP;Stein JL;Renteria ME;Arias-Vasquez A;Desrivières S;Jahanshad N;Toro R;Wittfeld K;Abramovic L;Andersson M;Aribisala BS;Armstrong NJ;Bernard M;Bohlken MM;Boks MP;Bralten J;Brown AA;Chakravarty MM;Chen Q;Ching CR;Cuellar-Partida G;den Braber A;Giddaluru S;Goldman AL;Grimm O;Guadalupe T;Hass J;Woldehawariat G;Holmes AJ;Hoogman M;Janowitz D;Jia T;Kim S;Klein M;Kraemer B;Lee PH;Olde Loohuis LM;Luciano M;Macare C;Mather KA;Mattheisen M;Milaneschi Y;Nho K;Papmeyer M;Ramasamy A;Risacher SL;Roiz-Santiañez R;Rose EJ;Salami A;Sämann PG;Schmaal L;Schork AJ;Shin J;Strike LT;Teumer A;van Donkelaar MM;van Eijk KR;Walters RK;Westlye LT;Whelan CD;Winkler AM;Zwiers MP;Alhusaini S;Athanasiu L;Ehrlich S;Hakobjan MM;Hartberg CB;Haukvik UK;Heister AJ;Hoehn D;Kasperaviciute D;Liewald DC;Lopez LM;Makkinje RR;Matarin M;Naber MA;McKay DR;Needham M;Nugent AC;Pütz B;Royle NA;Shen L;Sprooten E;Trabzuni D;van der Marel SS;van Hulzen KJ;Walton E;Wolf C;Almasy L;Ames D;Arepalli S;Assareh AA;Bastin ME;Brodaty H;Bulayeva KB;Carless MA;Cichon S;Corvin A;Curran JE;Czisch M;de Zubicaray GI;Dillman A;Duggirala R;Dyer TD;Erk S;Fedko IO;Ferrucci L;Foroud TM;Fox PT;Fukunaga M;Gibbs JR;Göring HH;Green RC;Guelfi S;Hansell NK;Hartman CA;Hegenscheid K;Heinz A;Hernandez DG;Heslenfeld DJ;Hoekstra PJ;Holsboer F;Homuth G;Hottenga JJ;Ikeda M;Jack CR;Jenkinson M;Johnson R;Kanai R;Keil M;Kent JW;Kochunov P;Kwok JB;Lawrie SM;Liu X;Longo DL;McMahon KL;Meisenzahl E;Melle I;Mohnke S;Montgomery GW;Mostert JC;Mühleisen TW;Nalls MA;Nichols TE;Nilsson LG;Nöthen MM;Ohi K;Olvera RL;Perez-Iglesias R;Pike GB;Potkin SG;Reinvang I;Reppermund S;Rietschel M;Romanczuk-Seiferth N;Rosen GD;Rujescu D;Schnell K;Schofield PR;Smith C;Steen VM;Sussmann JE;Thalamuthu A;Toga AW;Traynor BJ;Troncoso J;Turner JA;Valdés Hernández MC;van 't Ent D;van der Brug M;van der Wee NJ;van Tol MJ;Veltman DJ;Wassink TH;Westman E;Zielke RH;Zonderman AB;Ashbrook DG;Hager R;Lu L;McMahon FJ;Morris DW;Williams RW;Brunner HG;Buckner RL;Buitelaar JK;Cahn W;Calhoun