Dr Jill McMahon

BSc, MPhil, PhD.

Contact Details

Senior Researcher
MS Research Group, 1st Floor North,
Biomedical Sciences Building,
Newcastle Road,
NUI Galway

T: Ext. 4440
E: jill.mcmahon@nuigalway.ie
 
researcher

Biography

Research Interests

Neuroscience, neurological disease, multiple sclerosis, demyelination, mild traumatic brain injury, sports-related head injury, ER stress, unfolded protein response, gene & cell therapy, cell death, skeletal muscle, immunology, biomarkers

Peer Reviewed Journals

  Year Publication
(2016) 'Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model'
Healy, S,McMahon, J,Owens, P,FitzGerald, U (2016) 'Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model'. Scientific Reports, 6 [DOI] [Details]
(2015) 'Differential activation of ER stress pathways in myelinating cerebellar tracts'
Naughton, MC,McMahon, JM,FitzGerald, U (2015) 'Differential activation of ER stress pathways in myelinating cerebellar tracts'. International Journal Of Developmental Neuroscience, 47 :347-360 [DOI] [Details]
(2014) 'Mesenchymal stem cells and a vitamin D receptor agonist additively suppress T helper 17 cells and the related inflammatory response in the kidney'
Duffy, MM,McNicholas, BA,Monaghan, DA,Hanley, SA,McMahon, JM,Pindjakova, J,Alagesan, S,Fearnhead, HO,Griffin, MD (2014) 'Mesenchymal stem cells and a vitamin D receptor agonist additively suppress T helper 17 cells and the related inflammatory response in the kidney'. American Journal Of Physiology-Renal Physiology, 307 :1412-1426 [DOI] [Details]
(2013) 'Calreticulin and other components of endoplasmic reticulum stress in rat and human inflammatory demyelination'
Ni Fhlathartaigh, M.,McMahon, J.,Reynolds, R.,Connolly, D.,Higgins, E.,Counihan, T.,Fitzgerald, U. (2013) 'Calreticulin and other components of endoplasmic reticulum stress in rat and human inflammatory demyelination'. Acta Neuropathologica Communications, 1 [Details]
(2013) 'Mesenchymal Stem Cell Survival in the Infarcted Heart Is Enhanced by Lentivirus Vector-Mediated Heat Shock Protein 27 Expression'
McGinley, LM,McMahon, J,Stocca, A,Duffy, A,Flynn, A,O'Toole, D,O'Brien, T (2013) 'Mesenchymal Stem Cell Survival in the Infarcted Heart Is Enhanced by Lentivirus Vector-Mediated Heat Shock Protein 27 Expression'. Human Gene Therapy, 24 :840-851 [DOI] [Details]
(2013) 'Liposomal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'
Ganly, S,Hynes, SO,Sharif, F,Aied, A,Barron, V,McCullagh, K,McMahon, J,McHugh, P,Crowley, J,Wang, WX,O'Brien, T,Greiser, U (2013) 'Liposomal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature'. J Control Release, 167 :109-119 [DOI] [Details]
(2012) 'Increased expression of ER stress- and hypoxia-associated molecules in grey matter lesions in multiple sclerosis'
McMahon, JM,McQuaid, S,Reynolds, R,FitzGerald, UF (2012) 'Increased expression of ER stress- and hypoxia-associated molecules in grey matter lesions in multiple sclerosis'. Multiple Sclerosis Journal, 18 :1437-1447 [DOI] [Details]
(2011) 'Expression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis'
Cunnea, P,Mhaille, AN,McQuaid, S,Farrell, M,McMahon, J,FitzGerald, U (2011) 'Expression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis'. Multiple Sclerosis Journal, 17 :808-818 [DOI] [Details]
(2011) 'Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia'
McGinley, L,McMahon, J,Strappe, P,Barry, F,Murphy, M,O'Toole, D,O'Brien, T (2011) 'Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia'. Stem Cell Research & Therapy, 2 [DOI] [Details]
(2010) 'Bolus Delivery of Mesenchymal Stem Cells to Injured Vasculature in the Rabbit Carotid Artery Produces a Dysfunctional Endothelium'
O'Shea, CA,Hynes, SO,Shaw, G,Coen, BA,Hynes, AC,McMahon, J,Murphy, M,Barry, F,O'Brien, T (2010) 'Bolus Delivery of Mesenchymal Stem Cells to Injured Vasculature in the Rabbit Carotid Artery Produces a Dysfunctional Endothelium'. Tissue Engineering Part A, 16 :1657-1665 [DOI] [Details]
(2010) 'Gene expression analysis of the microvascular compartment in multiple sclerosis using laser microdissected blood vessels'
Cunnea, P,McMahon, J,O'Connell, E,Mashayekhi, K,Fitzgerald, U,McQuaid, S (2010) 'Gene expression analysis of the microvascular compartment in multiple sclerosis using laser microdissected blood vessels'. Acta Neuropathologica, 119 :601-615 [DOI] [Details]
(2009) 'Comparison of Viral and Nonviral Vectors for Gene Transfer to Human Endothelial Progenitor Cells'
Kealy, B,Liew, A,McMahon, JM,Ritter, T,O'Doherty, A,Hoare, M,Greiser, U,Vaughan, EE,Maenz, M,O'Shea, C,Barry, F,O'Brien, T (2009) 'Comparison of Viral and Nonviral Vectors for Gene Transfer to Human Endothelial Progenitor Cells'. Tissue Engineering Part C-Methods, 15 :223-231 [DOI] [Details]
(2008) 'Gene-eluting stents: Adenovirus-mediated delivery of eNOS to the blood vessel wall accelerates re-endothelialization and inhibits restenosis'
Sharif, F,Hynes, SO,Cooney, R,Howard, L,McMahon, J,Daly, K,Crowley, J,Barry, F,O'Brien, T (2008) 'Gene-eluting stents: Adenovirus-mediated delivery of eNOS to the blood vessel wall accelerates re-endothelialization and inhibits restenosis'. Molecular Therapy, 16 :1674-1680 [DOI] [Details]
(2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'
Sen, S,Conroy, S,Hynes, SO,McMahon, J,O'Doherty, A,Bartlett, JS,Akhtar, Y,Adegbola, T,Connolly, CE,Sultan, S,Barry, F,Katusic, ZS,O'Brien, T (2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'. Journal Of Gene Medicine, 10 :143-151 [DOI] [Details]
(2008) 'A non-apoptotic role for caspase-9 in muscle differentiation'
Murray, TVA,McMahon, JM,Howley, BA,Stanley, A,Ritter, T,Mohr, A,Zwacka, R,Fearnhead, HO (2008) 'A non-apoptotic role for caspase-9 in muscle differentiation'. Journal Of Cell Science, 121 :3786-3793 [DOI] [Details]
(2008) 'Increased expression of endoplasmic reticulum stress-related signaling pathway molecules in multiple sclerosis lesions'
Mhaille, AN,McQuaid, S,Windebank, A,Cunnea, P,McMahon, J,Samali, A,FitzGerald, U (2008) 'Increased expression of endoplasmic reticulum stress-related signaling pathway molecules in multiple sclerosis lesions'. Journal Of Neuropathology And Experimental Neurology, 67 :200-211 [Details]
(2007) 'The effect of cholecyst-derived extracellular matrix on the phenotypic behaviour of valvular endothelial and valvular interstitial cells'
Brody, S,McMahon, J,Yao, L,O'Brien, M,Dockery, P,Pandit, A (2007) 'The effect of cholecyst-derived extracellular matrix on the phenotypic behaviour of valvular endothelial and valvular interstitial cells'. Biomaterials, 28 :1461-1469 [DOI] [Details]
(2007) 'Identification of an inhibitor of caspase activation from heart extracts; ATP blocks apoptosome formation'
Samali, A,O'Mahoney, M,Reeve, J,Logue, S,Szegezdi, E,McMahon, J,Fearnhead, HO (2007) 'Identification of an inhibitor of caspase activation from heart extracts; ATP blocks apoptosome formation'. Apoptosis, 12 :465-474 [DOI] [Details]
(2006) 'Gene-eluting stents: Comparison of adenoviral and adeno-associated viral gene delivery to the blood vessel wall in vivo'
Sharif, F,Hynes, SO,McMahon, J,Cooney, R,Conroy, S,Dockery, P,Duffy, G,Daly, K,Crowley, J,Bartlett, JS,O'Brien, T (2006) 'Gene-eluting stents: Comparison of adenoviral and adeno-associated viral gene delivery to the blood vessel wall in vivo'. Human Gene Therapy, 17 :741-750 [Details]