Health / Biomedical / Clinical / Pre-clinical Sciences ProjectsLead InvestigatorLink to project description
Scaffold-mediated Spatiotemporal Multimodal Biomolecule Delivery to Treat Limb Ischemia Abhay PanditDownload PDF
Enhancing Sulphated Glycosaminoglycan (sGAG) Production using a Hyaluronan Nanoparticle-based Delivery SystemAbhay PanditDownload PDF
Optimised Functionalised Construct to Repair the Annulus Fibrosus (AF) of the Intervertebral Disc Abhay PanditDownload PDF
Functionalised Biomaterial Scaffold for Spinal Cord Repair Abhay PanditDownload PDF
Scaffold-mediated Spatiotemporal Multimodal Biomolecule Delivery to Treat Limb IschemiaAbhay PanditDownload PDF
Optimised Functionalised Construct to Repair the Annulus Fibrosus (AF) of the Intervertebral DiscAbhay PanditDownload PDF
Functionalised Biomaterial Scaffold for Spinal Cord RepairAbhay PanditDownload PDF
Mechanism of NGF-induced pro-survival signallingAdrienne GormanDownload PDF
Investigation into loss of p75 neurotrophin receptor in progression of prostate cancerAdrienne GormanDownload PDF
Investigation into role of p75 neurotrophin receptor in chronic lymphocytic leukemiaAdrienne GormanDownload PDF
Unfolded Protein Response modulation of epithelial mesenchymal transit (EMT)Afshin SamaliDownload PDF
TARGETING MEVALONATE CASCADE IN BREAST CANCERAfshin SamaliDownload PDF
Assessment and management of disorders of consciousness in childrenAgnes ShielDownload PDF
Heterogeneity of Disorders of ConsciousnessAgnes ShielDownload PDF
Patterns of recovery after severe brain injuryAgnes ShielDownload PDF
Constraint induced movement therapy in people with long term motor impairment after traumatic brain injuryAgnes ShielDownload PDF
Disorders of consciousness in neurodegenerative conditionsAgnes ShielDownload PDF
Efficacy and application of rehabilitation with people with dementiaAgnes ShielDownload PDF
Introduction of a new antimicrobial (Fosfomycin) in community care: an observational study of the factors that influence prescribing of this new antimicrobial and longitudinal follow up of the impact of this introduction on the occurrence and spread of resistance.Akke VellingerDownload PDF
The impact of antibiotic guidelines in hospitals on the occurrence of resistance of hospital infectionsAkke VellingerDownload PDF
Validation of a novel breath test for the diagnosis of diabetesAmir ShafatDownload PDF
Lifestyle and Insulin ResistanceAmir ShafatDownload PDF
Chromatin features contributing to stem cell properties in early animalsAndrew FlausDownload PDF
Role of altered microhaemodynamics of the liver in the regeneration of liver: An intravital fluorescence microscopy (IVFM) studyAntony M WheatleyDownload PDF
Role of the innate immune system in liver regeration: role played by toll-like receptor pathwaysAntony M WheatleyDownload PDF
Involvement of the hepatic microcirculation in the regeneration of the cirrhotic liver of the mouseAntony M WheatleyDownload PDF
Role of the innate immune system on the microcirculation of the kidney following ischaemia-reperfusion (I-R) injury: An intravital fluorescence microscopy (IVFM) studyAntony M WheatleyDownload PDF
Role of the innate immune system gastrointestinal permeability: An intravital fluorescence microscopy (IVFM) studyAntony M WheatleyDownload PDF
Host cell responses to pathogenic bacteria – the role of the cellular stress pathways.Aoife BoydDownload PDF
Novel virulence factors of Vibrio parahaemolyticusAoife BoydDownload PDF
Type III Secretion Systems of Vibrio parahaemolyticusAoife BoydDownload PDF
Targeting IRE1 in Breast CancerAshin SamaliDownload PDF
The role of ER stress in innate immunityAshin SamaliDownload PDF
Nanoparticle-Mediated Delivery of Superoxide Dismutase in Sepsis Induced Lung InjuryBrendan HigginsDownload PDF
A longitudinal study of Omega-3 Essential Fatty Acids (EFAs) and their association with grey and white matter in both healthy controls and individuals with bipolar disorderBrian HallahanDownload PDF
Deciphering the regulatory roles and mechanisms of non-coding miRNAs in thyroid cancer Charles SpillaneDownload PDF
Understanding the interplay between exercise and plant-derived nutraceuticals: Circulating miRNAs as biomarkers for personalised sports training regimesCharles SpillaneDownload PDF
Circulating miRNAs as biomarkers for high-altitude sports training regimesCharles SpillaneDownload PDF
Circulating miRNAs as biomarkers for differentiated sports training regimes for the young and elderlyCharles SpillaneDownload PDF
Deciphering the regulatory roles and mechanisms of the non-coding microRNA mir-9 in breast cancerCharles SpillaneDownload PDF
Molecular genetic and epigenetic analysis of the regulatory role of the non-coding microRNA mir18a in breast and endometrial cancerCharles SpillaneDownload PDF
Ensuring the voice of young carers in developing relevant services and supportColette KellyDownload PDF
Molecular mechanisms of stress sensing in the food-borne bacterial pathogen Listeria monocytogenesConor O'ByrneDownload PDF
A functional metagenomic screen for stress adaptation mechanisms encoded by the microbiota in the human gutConor O'ByrneDownload PDF
Investigating the efficacy of selected progenitor cells to improve diabetic fracture healing.Cynthia Coleman,Download PDF
Use of novel marine extracts in reducing Campylobacter colonisation of broilersCyril CarrollDownload PDF
Host-pathogen interactions of Campylobacter jejuniCyril CarrollDownload PDF
Development of aantimicrobial resistance in Campylobacter jejuni biofilms.Cyril CarrollDownload PDF
Effect of antimicrobials on Campylobacteri BiofilmsCyril CarrollDownload PDF
Pattern Recognition in Clinical Neuroimaging of Psychiatric DisordersDara M CannonDownload PDF
Diffusion Magnetic Resonance Imaging and Post-Mortem Investigation of White Matter Microstructural Organization in the Human BrainDara M CannonDownload PDF
Epigenetic regulation of innate immune responses:Declan MckernanDownload PDF
In vitro cartilage organogenesis: The project aims to modulate the in vitro microenvironment of chondrocytes to build a host specific cartilage.Dimitrios ZeugolisDownload PDF
In vitro corneal organogenesis: The project aims to modulate the in vitro microenvironment of corneal derived cells to build a corneal tissue in the lab.Dimitrios ZeugolisDownload PDF
In vitro peripheral nerve organogenesis: The project aims to modulate the in vitro microenvironment of neural cells and fibroblasts to build a peripheral nerve implant.Dimitrios ZeugolisDownload PDF
In vitro skin organogenesis: The project aims to modulate the in vitro microenvironment of skin derived cells to build a full thickness skin equivalent.Dimitrios ZeugolisDownload PDF
In vitro tendon organogenesis: The project aims to modulate the in vitro microenvironment of tendon derived cells to build a tendon tissue in the lab.Dimitrios ZeugolisDownload PDF
Biosensors for biomarkersDonal LeechDownload PDF
Genes by environment interactions for modelling Parkinson’s disease.Eilís DowdDownload PDF
To investigate if basal-like breast tumours have a distinct pattern of DNA damage response or centrosome biology that can predict patient outcome and response to treatmentEmer BourkeDownload PDF
Development of treatment strategies to target and eradicate leukemic stem cellsEva SzegezdiDownload PDF
Development of novel drugs for activating death receptor-mediated killing of tumoursEva SzegezdiDownload PDF
Structure and molecular composition of human non-complicated diabetic skinFabio QuondamatteoDownload PDF
Role of autophagy gene AMBRA in tumorigenesis – Characterization of neoplasiasFabio QuondamatteoDownload PDF
Structure and molecular composition of skin in a model of type 1 diabetes mellitusFabio QuondamatteoDownload PDF
An Investigation of Diabetes, Obesity and AutismGeraldine LeaderDownload PDF
An Investigation of Autism Spectrum Disorder in Adults and Older Adults.Geraldine LeaderDownload PDF
Functionalisation of cardiovascular stents for improved in vivo performanceGerard WallDownload PDF
Delivery of superoxide dismutase to the lung for therapyGerard WallDownload PDF
Morphogenesis of the inner ear in Xenopus laevisGerhard SchlosserDownload PDF
Role of posttranslational modifications of the protein Eya1 for neurogenesisGerhard SchlosserDownload PDF
Does epistasis drive coevolution?Gerhard SchlosserDownload PDF
P54nrb a novel player in the DNA damage responseHeinz Peter NasheuerDownload PDF
Complex formation, mobility and concentration of DNA replication and DNA repair proteins in the cell cycle and after DNA damageHeinz Peter NasheuerDownload PDF
Cellular Small Non-Coding RNAs Highly Active in Inhibiting Polyoma Viral DNA Replication.Heinz Peter NasheuerDownload PDF
Distribution and abundance of H2AX in human mesenchymal stem cells.Helen DodsonDownload PDF
The role of caspase-9 in differentiationHoward FearnheadDownload PDF
Caspase-mediated proteolysis during myoblast differentiationHoward FearnheadDownload PDF
Repurposing drugs for the treatment of Advanced CancersHoward FearnheadDownload PDF
Development & evaluation of a novel biopolymer composite for healing of bone defects.Jessica Hayes Download PDF
Development of Biofunctionalised Implants for Orthopaedic ApplicationsJessica Hayes Download PDF
Does repeated methamphetamine exposure to rats produce lasting changes in central serotonergic circuitry and function?John KellyDownload PDF
Advanced Gene Therapy Vectors for ALI/ARDSJohn LaffeyDownload PDF
iPS therapy for ALI/ARDSJohn LaffeyDownload PDF
MSC Therapy for Lung Ischaemia/Reperfusion InjuryJohn LaffeyDownload PDF
Investigation of the neurotoxic effects of methamphetamineKaren DoyleDownload PDF
Investigation of the neuroprotective potential of neurotrophins for strokeKaren DoyleDownload PDF
Investigation of the involvement of polyamines in the pathophysiology of strokeKaren DoyleDownload PDF
Targeting Endo/Sarcoplasmic Reticulum Stress as a novel therapy for muscle disorders.Karl MccullaghDownload PDF
A gene therapy appproach to muscle disordersKarl MccullaghDownload PDF
Targeting Endo/Sarcoplasmic Reticulum Stress as a novel therapy for muscle disordersKarl MccullaghDownload PDF
GUT-Liver axis and inflammatory disease - role of concanavalin A mediated changes in gut permeability. Leo QuinlanDownload PDF
Application of subsensory electrical noise as a neuromodulatory therapy in Motor disordersLeo QuinlanDownload PDF
Application of subsensory electrical noise as a neuromodulatory therapy in the loss of sensory functionLeo QuinlanDownload PDF
Nongenomic steroid action on cellular structure and ion channel function in human reproductive tract - implications for fertility.Leo QuinlanDownload PDF
Nongenomic steroid action on cellular structure and ion channel function in bovine reproductive tract - implications for fertility.Leo QuinlanDownload PDF
Immune dysregulation in the postpartum cow and negative energy balance consequences for herd fertilityLeo QuinlanDownload PDF
Investigation of biomaterial in the treatment of interstitial cystitis. Leo QuinlanDownload PDF
A biomaterials approach to treatment of overactive urinary bladder targeting purinergic pathwaysLeo QuinlanDownload PDF
A biomaterials approach to treatment of overactive urinary bladder targeting purinergic signaling pathways.Leo QuinlanDownload PDF
A biomaterials approach to treatment of pain in bladder disease targeting histamine inflammatory pathwaysLeo QuinlanDownload PDF
GLYCOMARKERS FOR GASTROINTESTINAL CANCERSLokesh Joshi Download PDF
Fibrin/conducting polymer hybrids for neuroelectrode functionalizationManus BiggsDownload PDF
Bone mechanotransduction in health and diseaseManus BiggsDownload PDF
Osteoinductive ferroelectric polymers for bone tissue engineeringManus BiggsDownload PDF
Bone regeneration through biomimetic ferroelectric nanofibers within collagen scaffoldsManus BiggsDownload PDF
Applicants interested in conducintg doctoral research on the promotion of positive mental health and wellbeing are welcome to apply.Margaret BarryDownload PDF
Applicants interested in conducintg doctoral research on the development and application Health Promotion of core competencies are welcome to apply.Margaret BarryDownload PDF
Abnormal cognitive dynamics following premature birthMark ElliottDownload PDF
The role of Mesenchymal Stem Cells in Modulating Development of Osteoarthritis in the Damaged JointMary MurphyDownload PDF
Development of Strategies for Optimised Engraftment and Chondrogenic Differentiation of Mesenchymal Stem Cells for Cartilage Repair in OsteoarthritisMary MurphyDownload PDF
Cross-cultural analysis of women’s stories of birth.Marypat O Malley-KeighranDownload PDF
Cross cultural analysis of mediated discourses of cosmetic surgery & dermatologyMarypat O Malley-KeighranDownload PDF
Cross cultural analysis of women’s experiences of cosmetic surgery & dermatologyMarypat O Malley-KeighranDownload PDF
Mesenchymal stem cells modulation of innate immune response to allogeneic pancreatic isletsMatthew GriffinDownload PDF
Dendritic cells and the intra-renal T-cell repertoire in kidney diseaseMatthew GriffinDownload PDF
Mesenchymal stem cell and vitamin D re-programming of macrophages in kidney diseaseMatthew GriffinDownload PDF
Development of a zebrafish model of the congenital heart disorder, arrhythmogenic right ventricular cardiomyopathy (ARVC). Maura GrealyDownload PDF
Personalised Intensive Care Medicine Using Probabilistic Model-Based Data AnalyticsMichael MaddenDownload PDF
New Techniques for Analysis of Intensive Care Unit DataMichael MaddenDownload PDF
The identification of new inhibitors of cellular adhesion and trafficking in multiple myelomaMichael O’DwyerDownload PDF
Circulating microRNAs in Breast CancerMichael KerinDownload PDF
Glia: the glue that link depression and pain Michelle RocheDownload PDF
Endocannabinoid modulation of neuroinflammation Michelle RocheDownload PDF
A conditional approach to probing ATR function during DNA synthesisNoel Francis LowndesDownload PDF
The role of molecular motor proteins in DNA repair:Noel Francis LowndesDownload PDF
The role of RNA binding protein in the cellular responses to DNA damageNoel Francis LowndesDownload PDF
The role of chromatin remodelling in the cellular responses to DNA damageNoel Francis LowndesDownload PDF
Identification and characterisation of novel proteins involved in the DNA damage response pathways after UV-irradiationNoel Franics LowndesDownload PDF
Noise induced hearing loss in younger people through over exposure to music through headphones and earphones is growing in its importance as a major health concern.Padriag MolloyDownload PDF
The cellular effects of endocrine disrupting chemicals on the female reproductive systemPeter Dockery Download PDF
Mechanisms of Triplet Repeat Instability in Eukaryotes.Robert LahueDownload PDF
Mesencyhmal Stem Cell (MSC)-mediated Gene Therapy for Breast CancerRoisin DwyerDownload PDF
Generating and phenotyping Induced Pluripotent Stem (iPS) cells from ALS Patients.Sanbing ShenDownload PDF
Generating Induced Pluripotent Stem (iPS) cell model for autism.Sanbing ShenDownload PDF
Generating and phenotyping Induced Pluripotent Stem (iPS) cells for Fragile X syndrome.Sanbing ShenDownload PDF
Phenotyping a novel knockout mouse on brain development and function.Sanbing ShenDownload PDF
FUNCTION AND REGULATION OF microRNA BIOGENESIS DURING UNFOLDED PROTEIN RESPONSESanjeev GuptaDownload PDF
Regulation of NCOA3 by miR-17 and its role in resistance to endocrine therapy of breast cancerSanjeev GuptaDownload PDF
IDENTIFICATION AND CHARACTERIZATION OF miRNAs A BIOMAKERS FOR BREAST CANCERSanjeev GuptaDownload PDF
Role of miR-17-92 cluster in regulating fate of cardiomyocytes during ischemiaSanjeev GuptaDownload PDF
REGULATION OF DICER EXPRESSION BY ESTROGEN AND ITS ROLE IN RESISTANCE TO ENDOCRINE THERAPY OF BREAST CANCERSanjeev GuptaDownload PDF
This PhD project will involve participation in the international HBSC network (www.hbsc.org) with a focus on health and social inequalities in adolescent sexual health across EuropeSaoirse Nic GabhainnDownload PDF
This PhD project will aim to develop participative research methods for use with children with chronic illness and disability, building on existing techniques developed in the research team, the applicant will develop and test methods for allowing children with disability a full voice in all matters that effect them.Saoirse Nic GabhainnDownload PDF
This PhD project will involve participation in the international HBSC network (www.hbsc.org) with a focus on early onset of risk behaviours such as substance use and sexual behaviour and the impact of such early onset on adolescent health.Saoirse Nic GabhainnDownload PDF
This PhD project will on migrant youth and their health, particularly how migrants are clustered together or separated from others from their countries of origin and the impact this has on youth health.Saoirse Nic GabhainnDownload PDF
This PhD project will focus on the health behaviours and socio-ecological context of vulnerable children – those who do not live with their parents. It will involve secondary data analysis of existing data sources and original qualitative data collection on health priorities of these youth.Saoirse Nic GabhainnDownload PDF
This PhD project will involve participation in the international HBSC network (www.hbsc.org) with a focus on the application of geographical information systems to adolescent health and well-being – to study the impact of location and physical context on child and adolescent health.Saoirse Nic GabhainnDownload PDF
This PhD project will focus on giving children and adolescents a voice in all aspects of the research process – involving young people from study inception, design, execution, analysis and presentation – with a view to documenting the contribution that young people can make and the challenges for researchers and the research process in including them.Saoirse Nic GabhainnDownload PDF
This PhD project will concentrate on the range of symptoms commonly reported by adolescents (such as headache, feeling irritable, feeling low) – how they are related to health outcomes and the contexts of health, how they are interpreted by adolescents, common medical responses to such symptoms and an analysis of the popular adolescent media about sympoms.Saoirse Nic GabhainnDownload PDF
Targeting stress pathways in prostate cancerSharon GlynnDownload PDF
Investigating chromatin modifications as a novel prognostic indicator in Prostate CancerStephen ReaDownload PDF
Epigenetic mechanisms involved in chronic pain Stephen ReaDownload PDF
Investigating the role of histone modifications in neuro-epigenetic memoryStephen ReaDownload PDF
Development and application of rapid Point of Care (PoC) molecular diagnostics assays based on novel biomarkers for Cancer diagnosis and treatment monitoring Terry SmithDownload PDF
Investigation of the transcriptomic effects of steroid hormone treatment on contractility associated gene expression linked to labour in a human uterine smooth muscle cell culture model Terry SmithDownload PDF
Investigation of circulating miRNA profiles in women with gestational diabetes versus non-diabetic pregnant women using Next Generation Sequencing (NGS) approachesTerry SmithDownload PDF
Investigation of circulating miRNA profiles in pregnant non-labouring and in-labour women using Next Generation Sequencing (NGS) approachesTerry SmithDownload PDF
Understanding the immunomodulatory properties of mesenchymal stem cells on “licensing” of pathogenic T cells in the lungThomas RitterDownload PDF
Regulating immunogenicity and tolerogenicity through cell surface glycosylationThomas RitterDownload PDF
SeekTB/SeekNTM - Novel multi parametric Nucleic Acid Tests to Help in Global Effort to Control Tuberculosis and Non Tuberculosis Mycobacteria InfectionsThomas BarryDownload PDF
Development of a novel cell-free treatment protocol for cornea transplantation: Mesenchymal stem cell derived exosomes for the prevention of corneal graft rejection and characterisation of the underlying mechanismsThomas RitterDownload PDF
Elucidating the mechanism of immunomodulation by syngeneic and allogeneic mesenchymal stem cells.Thomas RitterDownload PDF
Enhancement of in vivo therapeutic properties of differentiated allogeneic mesenchymal stem cells by genetic modificationThomas RitterDownload PDF
Application of novel immunoregulatory molecules in Cornea transplantationThomas RitterDownload PDF
Phenotyping a novel knockout mouse as a model for human cardiovascular disease.Timothy O'BrienDownload PDF
The role of chaperone proteins BiP and calreticulin in multiple sclerosisUna FitzgeraldDownload PDF
Early development and acquisition of cellular commitment in HydractiniaUri FrankDownload PDF
Advanced biomaterials- based dressings containing stem cells for the treatment of diabetic foot ulcersWenxin WangDownload PDF