Dr Kate Reddington

Ph.D

 
researcher
 

Biography

Dr Reddington is a lecturer on the Microbiology pathway in the School of Biological and Chemical Sciences at University of Galway. Her research focuses on the development of innovative solutions for infectious disease diagnostics and public health microbiology. Of particular interest to her research group is the application of whole genome sequencing in clinical microbiology, both from human and healthcare environmental reservoir samples.

Dr Reddington was a member of the National Coronavirus Sequencing Consortium and was a member of the HSE COVID19 Laboratory R&D Product Solutions Group. 

Dr Reddington is also the chair of Research and Innovation for the School of Biological and Chemical Sciences.


Research Interests

Research interests include Molecular based infectious disease diagnostic; Clinical and environmental microbiology; Whole genome Sequencing; Antimicrobial Resistance Detection; Implementation of whole genome sequencing approaches to public health microbiology

Research Projects

  Project Start Date End Date
DEVELOPMENT OF A VIRAL RESPIRATORY PANEL MULTIPLEX REAL-TIME PCR - EI FUNDS 01-MAY-20 30-APR-27
DEVELOPMENT OF A VIRAL RESPIRATORY PANEL MULTIPLEX REAL-TIME PCR - INDUSTRY FUNDS 01-MAY-20 30-APR-27
Irish Coronavirus Sequencing Consortium 01-APR-20
Development of untargeted and targeted portable and rapid molecular diagnostics of bacterial and viral pathogens associated with Bovine Respiratory Disease 01-OCT-18
DETERMINING THE COMMERCIAL FEASIBILITY OF RAPID MICROBIAL TEST SOLUTIONS FOR USE IN THE BIOLOGICS INDUSTRY SECTOR 16-OCT-17 30-APR-18
GENERAL RESEARCH ACCOUNT KATE REDDINGTON 27-MAY-16 26-MAY-26
RAP-ID: Rapid Aqua Pathogen Identification 01-JAN-16 30-JUN-17
Rapid Identification of Repiratory Tract Infections (RiD-RTI) 01-JUL-12 31-DEC-15
Rapid Culture independent nucleic acid diagnostics technologies for use in the analysis of microbial biocontamination of water distribution and centralised air conditioning systems 12-JAN-15 18-MAY-15

Contract Researchers

  Researcher Name Project Role Funding Body
Dr Gustavo Sambrano DEVELOPMENT OF A VIRAL RESPIRATORY PANEL MULTIPLEX REAL-TIME PCR Postdoctoral Researcher Enterprise Ireland (EI)
Dr Elizabeth Minogue DEVELOPMENT OF A VIRAL RESPIRATORY PANEL MULTIPLEX REAL-TIME PCR Postdoctoral Researcher Enterprise Ireland (EI)

Peer Reviewed Journals

  Year Publication
(2023) 'Design, Development, and Validation of a Culture-Independent Nucleic Acid Diagnostics Method for the Rapid Detection and Quantification of the Burkholderia cepacia Complex in Water with an Equivalence to ISO/TS 12869:2019'
Huong Duong and Shannon Fullbrook and Kate Reddington and Elizabeth Minogue and Thomas Barry (2023) 'Design, Development, and Validation of a Culture-Independent Nucleic Acid Diagnostics Method for the Rapid Detection and Quantification of the Burkholderia cepacia Complex in Water with an Equivalence to ISO/TS 12869:2019'. PDA Journal of Pharmaceutical Science and Technology, 77 (4):296-310 [DOI] [Details]
(2022) 'Assessment of Rapid MinION Nanopore DNA Virus Meta-Genomics Using Calves Experimentally Infected with Bovine Herpes Virus-1'
Esnault, Gaelle and Earley, Bernadette and Cormican, Paul and Waters, Sinead M. and Lemon, Ken and Cosby, S. Louise and Lagan, Paula and Barry, Thomas and Reddington, Kate and McCabe, Matthew S. (2022) 'Assessment of Rapid MinION Nanopore DNA Virus Meta-Genomics Using Calves Experimentally Infected with Bovine Herpes Virus-1'. Viruses, 14 (9) [DOI] [Details]
(2021) 'Legionella antibiotic susceptibility testing: is it time for international standardization and evidence-based guidance?'
Edward Portal, Ghislaine Descours, Christophe Ginevra, Massimo Mentasti, Baharak Afshar, Meera Chand, Jessica Day, Fedoua Echahidi, Laura Franzin, Valeria Gaia, Christian Lu¨ ck, Alaeddine Meghraoui, Jacob Moran-Gilad, Maria Luisa Ricci, Gerard Lina, Søren Uldum, Jonas Winchell, Robin Howe, Kathryn Bernard, Owen B. Spiller, Victoria J. Chalker and Sophie Jarraud on behalf of the ESCMID Study Group for Legionella Infections (ESGLI) (2021) 'Legionella antibiotic susceptibility testing: is it time for international standardization and evidence-based guidance?'. Journal Of Antimicrobial Chemotherapy. J Antimicrob Chemother, [Details]
(2021) 'Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021'
Funk, Tjede and Pharris, Anastasia and Spiteri, Gianfranco and Bundle, Nick and Melidou, Angeliki and Carr, Michael and Gonzalez, Gabriel and Garcia-Leon, Alejandro and Crispie, Fiona and O’Connor, Lois and Murphy, Niamh and Mossong, Joël and Vergison, Anne and Wienecke-Baldacchino, Anke K. and Abdelrahman, Tamir and Riccardo, Flavia and Stefanelli, Paola and Di Martino, Angela and Bella, Antonino and Lo Presti, Alessandra and Casaca, Pedro and Moreno, Joana and Borges, Vítor and Isidro, Joana and Ferreira, Rita and Gomes, João Paulo and Dotsenko, Liidia and Suija, Heleene and Epstein, Jevgenia and Sadikova, Olga and Sepp, Hanna and Ikonen, Niina and Savolainen-Kopra, Carita and Blomqvist, Soile and Möttönen, Teemu and Helve, Otto and Gomes-Dias, Joana and Adlhoch, Cornelia and on b (2021) 'Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021'. Eurosurveillance, 26 (16) [DOI] [Details]
(2016) 'Development of internally controlled duplex real-time NASBA diagnostics assays for the detection of microorganisms associated with bacterial meningitis'
Clancy E, Coughlan H, Higgins O, Boo TW, Cormican M, Barrett L, Smith TJ, Reddington K, Barry T (2016) 'Development of internally controlled duplex real-time NASBA diagnostics assays for the detection of microorganisms associated with bacterial meningitis'. Journal Of Microbiological Methods, 127 [DOI] [Details]
(2016) 'The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis'
Alison Devonshire; Denise O'Sullivan; Isobella Honeyborne; Gerwyn Jones; Maria Karczmarczyk; Jernej Pavši¿; Alice Gutteridge; Mojca Milavec; Pablo Mendoza; Heinz Schimmel; Fran Van-Heuverswyn; Rebecca Gorton; Daniela Cirillo; Emanuele Borroni; Kathryn Harris; Marinus Barnard; Anthenette Heydenrych; Norah Ndusilo; Carole Wallis; Keshree Pillay; Thomas Barry; Kate Reddington; Elvira Richter; Erkan Mozio¿lu; Sema Akyürek; Burhanettin Yalç¿nkaya; Muslum Akgoz; Jana Žel; Carole Foy; Timothy McHugh; Jim Huggett (2016) 'The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis'. BMC Infectious Diseases, [Details]
(2020) 'Metagenomic analysis of planktonic riverine microbial consortia using nanopore sequencing reveals insight into river microbe taxonomy and function (vol 9, giaa053, 2020)'
Reddington, K;Eccles, D;O'Grady, J;Drown, DM;Hansen, LH;Nielsen, TK;Ducluzeau, AL;Leggett, RM;Heavens, D;Peel, N;Snutch, TP;Bayega, A;Oikonomopoulos, S;Ragoussis, J;Barry, T;van der Helm, E;Jolic, D;Richardson, H;Jansen, H;Tyson, JR;Jain, M;Brown, BL (2020) 'Metagenomic analysis of planktonic riverine microbial consortia using nanopore sequencing reveals insight into river microbe taxonomy and function (vol 9, giaa053, 2020)'. Gigascience, 9 [DOI] [Details]
(2011) 'Novel Multiplex Real-Time PCR Diagnostic Assay for Identification and Differentiation of Mycobacterium tuberculosis, Mycobacterium canettii, and Mycobacterium tuberculosis Complex Strains'
Reddington, K;O'Grady, J;Dorai-Raj, S;Maher, M;van Soolingen, D;Barry, T (2011) 'Novel Multiplex Real-Time PCR Diagnostic Assay for Identification and Differentiation of Mycobacterium tuberculosis, Mycobacterium canettii, and Mycobacterium tuberculosis Complex Strains'. Journal Of Clinical Microbiology, 49 :651-657 [DOI] [Details]
(2011) 'A Novel Multiplex Real-Time PCR for the Identification of Mycobacteria Associated with Zoonotic Tuberculosis'
Reddington, K;O'Grady, J;Dorai-Raj, S;Niemann, S;van Soolingen, D;Barry, T (2011) 'A Novel Multiplex Real-Time PCR for the Identification of Mycobacteria Associated with Zoonotic Tuberculosis'. Plos One, 6 [DOI] [Details]
(2012) 'SeekTB, a Two-Stage Multiplex Real-Time-PCR-Based Method for Differentiation of the Mycobacterium tuberculosis Complex'
Reddington, K;Zumla, A;Bates, M;van Soolingen, D;Niemann, S;Barry, T;O'Grady, J (2012) 'SeekTB, a Two-Stage Multiplex Real-Time-PCR-Based Method for Differentiation of the Mycobacterium tuberculosis Complex'. Journal Of Clinical Microbiology, 50 :2203-2206 [DOI] [Details]
(2013) 'Evaluation of a novel Listeria enrichment broth combined with a real-time PCR diagnostics assay for the specific detection of Listeria monocytogenes in RTE pork products'
Gomez, D;McGuinness, S;Reddington, K;O'Grady, J;Yanguela, J;Barry, T (2013) 'Evaluation of a novel Listeria enrichment broth combined with a real-time PCR diagnostics assay for the specific detection of Listeria monocytogenes in RTE pork products'. International Journal Of Food Science And Technology, 48 :1103-1108 [DOI] [Details]
(2013) 'Molecular Diagnosis of Active Pulmonary Tuberculosis'
Bateson, AL;Reddington, K;O'Grady, J (2013) 'Molecular Diagnosis of Active Pulmonary Tuberculosis'. Tuberculosis: Laboratory Diagnosis And Treatment Strategies, :13-33 [Details]
(2013) 'Diagnostics method for the rapid quantitative detection and identification of low-level contamination of high-purity water with pathogenic bacteria'
Minogue, E;Reddington, K;Dorai-Raj, S;Tuite, N;Clancy, E;Barry, T (2013) 'Diagnostics method for the rapid quantitative detection and identification of low-level contamination of high-purity water with pathogenic bacteria'. Journal Of Industrial Microbiology & Biotechnology, 40 :1005-1013 [DOI] [Details]
(2015) 'Future of Molecular Diagnostics: The Example of Infectious Diseases'
Clancy, E;Reddington, K;Barry, T;Huggett, JF;O'Grady, J (2015) 'Future of Molecular Diagnostics: The Example of Infectious Diseases'. Molecular Diagnostics: Current Research And Applications, :233-243 [Details]
(2015) 'Comparative genome analysis identifies novel nucleic acid diagnostic targets for use in the specific detection of Haemophilus influenzae'
Coughlan, H,Reddington, K,Tuite, N,Boo, TW,Cormican, M,Barrett, L,Smith, TJ,Clancy, E,Barry, T (2015) 'Comparative genome analysis identifies novel nucleic acid diagnostic targets for use in the specific detection of Haemophilus influenzae'. Diagnostic Microbiology And Infectious Disease, 83 :112-116 [DOI] [Details]
(2015) 'Comparison of Established Diagnostic Methodologies and a Novel Bacterial smpB Real-Time PCR Assay for Specific Detection of Haemophilus influenzae Isolates Associated with Respiratory Tract Infections'
Reddington, Kate and Schwenk, Stefan and Tuite, Nina and Platt, Gareth and Davar, Danesh and Coughlan, Helena and Personne, Yoann and Gant, Vanya and Enne, Virve I and Zumla, Alimuddin and others (2015) 'Comparison of Established Diagnostic Methodologies and a Novel Bacterial smpB Real-Time PCR Assay for Specific Detection of Haemophilus influenzae Isolates Associated with Respiratory Tract Infections'. Journal Of Clinical Microbiology, 53 (9):2854-2860 [DOI] [Details]
(2015) 'Cross Platform Standardisation of an Experimental Pipeline for Use in the Identification of Dysregulated Human Circulating MiRNAs'
Helena Kelly, Tim Downing, Nina L. Tuite, Terry J. Smith, Michael J. Kerin, Róisín M. Dwyer, Eoin Clancy, Thomas Barry, Kate Reddington (2015) 'Cross Platform Standardisation of an Experimental Pipeline for Use in the Identification of Dysregulated Human Circulating MiRNAs'. Plos One, [Details]
(2015) 'A rapid culture independent methodology to quantitatively detect and identify common human bacterial pathogens associated with contaminated high purity water'
Minogue, Elizabeth and Tuite, Nina L and Smith, Cindy J and Reddington, Kate and Barry, Thomas (2015) 'A rapid culture independent methodology to quantitatively detect and identify common human bacterial pathogens associated with contaminated high purity water'. BMC Biotechnol, 15 (1) [Details]
(2014) 'A current overview of commercially available nucleic acid diagnostics approaches to detect and identify human gastroenteritis pathogens'
Reddington, Kate and Tuite, Nina and Minogue, Elizabeth and Barry, Thomas (2014) 'A current overview of commercially available nucleic acid diagnostics approaches to detect and identify human gastroenteritis pathogens'. Biomolecular Detection and Quantification, 1 (1):3-7 [Details]
(2014) 'Rapid nucleic acid diagnostics for the detection of antimicrobial resistance in Gram-negative bacteria: is it time for a paradigm shift?'
Tuite, Nina and Reddington, Kate and Barry, Thomas and Zumla, Alimuddin and Enne, Virve (2014) 'Rapid nucleic acid diagnostics for the detection of antimicrobial resistance in Gram-negative bacteria: is it time for a paradigm shift?'. Journal Of Antimicrobial Chemotherapy, 69 (7):1729-1733 [Details]
(2013) 'Advances in multiparametric molecular diagnostics technologies for respiratory tract infections'
Reddington, Kate and Tuite, Nina and Barry, Thomas and O'Grady, Justin and Zumla, Alimuddin (2013) 'Advances in multiparametric molecular diagnostics technologies for respiratory tract infections'. Current opinion in pulmonary medicine, 19 (3):298-304 [Details]
(2013) 'Evaluation of a novel Listeria enrichment broth combined with a real-time PCR diagnostics assay for the specific detection of Listeria monocytogenes in RTE pork products'
Gomez, Diego and McGuinness, Sheila and Reddington, Kate and O'Grady, Justin and Yanguela, Javier and Barry, Thomas (2013) 'Evaluation of a novel Listeria enrichment broth combined with a real-time PCR diagnostics assay for the specific detection of Listeria monocytogenes in RTE pork products'. International Journal Of Food Science And Technology, 48 (5):1103-1108 [Details]
(2013) 'Diagnostics method for the rapid quantitative detection and identification of low-level contamination of high-purity water with pathogenic bacteria'
Minogue, Elizabeth and Reddington, Kate and Dorai-Raj, Siobhan and Tuite, Nina and Clancy, Eoin and Barry, Thomas (2013) 'Diagnostics method for the rapid quantitative detection and identification of low-level contamination of high-purity water with pathogenic bacteria'. Journal Of Industrial Microbiology & Biotechnology, 40 (9):1005-1013 [Details]
(2012) 'SeekTB, a two-stage multiplex real-time-PCR-based method for differentiation of the mycobacterium tuberculosis complex'
Reddington, Kate and Zumla, Alimuddin and Bates, Matthew and van Soolingen, Dick and Niemann, Stefan and Barry, Thomas and O'Grady, Justin (2012) 'SeekTB, a two-stage multiplex real-time-PCR-based method for differentiation of the mycobacterium tuberculosis complex'. Journal Of Clinical Microbiology, 50 (7):2203-2206 [Details]
(2012) 'Culture confirmation of Listeria monocytogenes using tmRNA as a diagnostics target'
Clancy, Eoin and Glynn, Barry and Reddington, Kate and Smith, Terry and Barry, Thomas (2012) 'Culture confirmation of Listeria monocytogenes using tmRNA as a diagnostics target'. Journal Of Microbiological Methods, 88 (3):427-429 [Details]
(2011) 'A novel multiplex real-time PCR for the identification of mycobacteria associated with zoonotic tuberculosis'
Reddington, Kate and O'Grady, Justin and Dorai-Raj, Siobhan and Niemann, Stefan and van Soolingen, Dick and Barry, Thomas (2011) 'A novel multiplex real-time PCR for the identification of mycobacteria associated with zoonotic tuberculosis'. Plos One, 6 (8) [Details]
(2011) 'Novel multiplex real-time PCR diagnostic assay for identification and differentiation of Mycobacterium tuberculosis, Mycobacterium canettii, and Mycobacterium tuberculosis complex strains'
Reddington, Kate and O'Grady, Justin and Dorai-Raj, Siobhan and Maher, Majella and van Soolingen, Dick and Barry, Thomas (2011) 'Novel multiplex real-time PCR diagnostic assay for identification and differentiation of Mycobacterium tuberculosis, Mycobacterium canettii, and Mycobacterium tuberculosis complex strains'. Journal Of Clinical Microbiology, 49 (2):651-657 [Details]

Book Chapters

  Year Publication
(2014) 'Future of Molecular Diagnostics: The Example of Infectious Diseases'
Clancy E, Reddington K, Barry T, Huggett J, O'Grady J (2014) 'Future of Molecular Diagnostics: The Example of Infectious Diseases' In: Molecular Diagnostics: Current Research and Applications. United Kingdom: Caister Academic Press. [Details]
(2013) 'Molecular diagnosis of active pulmonary tuberculosis'
Bateson, Anna L and Reddington, Kate and O'Grady, Justin and McHugh, TD and others (2013) 'Molecular diagnosis of active pulmonary tuberculosis' In: Tuberculosis: laboratory diagnosis and treatment strategies. :13-33 United Kingdom: CABI. [Details]

Conference Contributions

  Year Publication
(2017) 2nd International Conference on the Long and the Short of Non-Coding RNAs,
Shannon Fullbrook, Kate Reddington, Thomas Barry (2017) Toward the absolute quantification of Cryptococcus neoformans small RNAs. [Conference Organising Committee Chairperson], 2nd International Conference on the Long and the Short of Non-Coding RNAs, Greece , 09-JUN-17 - 14-JUN-17. [Details]
(2019) Annual Scientific Meeting of the One Health European Joint Programme,
Grainne McAndrew, Kate Reddington (2019) Towards elucidating the role, the hospital ICU environment plays in the transmission of ESKAPE pathogen related Healthcare Associated Infection. [Conference Organising Committee Chairperson], Annual Scientific Meeting of the One Health European Joint Programme, Dublin Ireland , 22-MAY-19 - 24-MAY-24. [Details]
(2020) FIS / HIS International,
Grainne McAndrew, Kate Reddington (2020) The Great ESKAPE: Are we Misdiagnosing Infections from Closely Related Species?. [Poster Presentation], FIS / HIS International, Virtual Conference , 09-NOV-20 - 11-NOV-20. [Details]
(2017) London Calling Event Oxford Nanopore,
Brown, B, Reddington, K, Richardson, H, Eccles, D, Jolic, D, Barry, T, Jansen, H, MARC, MitenJ and O'Grady, J. (2017) Metagenomic Analysis of Riverwater. [Poster Presentation (Refereed)], London Calling Event Oxford Nanopore, London , 03-MAY-17 - 05-MAY-17. [Details]

Reviews

  Year Publication
(2013) Advances in multiparametric molecular diagnostics technologies for respiratory tract infections.
Reddington, K;Tuite, N;Barry, T;O'Grady, J;Zumla, A (2013) Advances in multiparametric molecular diagnostics technologies for respiratory tract infections. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS Reviews [DOI] [Details]

Honours and Awards

  Year Title Awarding Body
2016 Ryan Award for Innovation Tony Ryan Trust and the Galway University Foundation
2012 Prof. Anthony P Moran award National University of Ireland, Galway
2011 Thomas Crawford Hayes Research award National University of Ireland, Galway
2008 College of Science Fellowship National University of Ireland, Galway

Professional Associations

  Association Function From / To
European Study Group for Legionella Infections (ESGLI) Member /
Microbiology Society Member /
European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Member /

Patents

  Patent Number Title Granted
EP20110746614 Diagnostic Method 08-APR-15
EP3523447 A method for the detection of legionella 22-JUN-22
EP3298163 Diagnostic method for bacterial organisms using the smpb gene 06-SEP-23

Committees

  Committee Function From / To
SBCS Research and Innovation Committee Chair of Committee 17-APR-23 /
SNS Education & Students Committee Microbiology Representative 02-SEP-18 / 31-AUG-22

Reviews

  Journal Role
Journal Of Medical Microbiology Reviewer
Tuberculosis Reviewer
Journal Of Clinical Microbiology Reviewer
Plos One Reviewer

Teaching Interests


  • Coordinator of 3rd Year Microbiology
  • Day to day supervision of a >20 final year undergraduate students performing research projects at NUI, Galway
  • Day to day supervision of a large number of thought MSc and PhD students performing their research projects in my research group

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
2019-present Microbial Genomics MI3101
2017-2018 Laboratory Practicals MI306 Laboratory Practicals
2017-present Scientific Communication MI406 Self-study Essay
2022-present Diagnostic Biotechnology BG5105 Diagnostic Biotechnology MSc Biotechnology
2018-present Genomics Techniques 1 BI5102
2018-present Biology BO101
2019/present The meaning of Life: Bioinformatics MI439
2018-present Problem solving MI413
2016-2017 Postgraduate Diploma in Applied Microbiology 1PGM1 Postgraduate Diploma in Applied Microbiology

Internal Collaborators

  Name Description of Collaboration
Dr Simone Coughlan
Analysis of coronavirus datasets generated from NUI Galway
Dr Thomas Barry

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
Dr Justin O'Grady University of East Anglia UNITED KINGDOM
Research Collaboration
Prof Alimuddin Zumla University College London UNITED KINGDOM
Research Collaboration
Dr Paul Cotter UCC IRELAND
Coordinator of National Coronavirus Sequencing Consortium
Dr Vicky Enne University College London UNITED KINGDOM
Research Collaboration
Dr Vanya Gant NHS Hospitals UNITED KINGDOM
Research Collaboration