Dr Beth Mallard

BSc, Ph.D

Contact Details

Lecturer Below The Bar
Physiology
School of Medicine
NUI Galway

E: BETH.MALLARD@nuigalway.ie
 
researcher

Biography

Beth Mallard received a BSC in Physiology in 2002 from the University of Otago in Dunedin, New Zealand. Following her undergraduate degree, she worked as a Research Assistant at Kings' College London/Guy's Hospital. She returned to New Zealand and was awarded a PhD from the University of Otago in 2011, studying "The role of Toll-like receptor 4 in Concanavalin A-induced immune-mediated hepatitis". She worked as a Teaching Fellow at the University of Otago for 2010-2011. She was appointed as a  Lecturer in Physiology in 2012.
Her current research interests include:
  • interaction between the gut and the liver
  • changes in gut permeability in acute and chronic liver injuries
  • examination of the microcirculation using intravital microscopy
  • the role of stress in acute and chronic liver injuries

Peer Reviewed Journals

  Year Publication
(2016) 'Delayed liver regeneration in C3H/HeJ mice: Possible involvement of haemodynamic and structural changes in the hepatic microcirculation'
Marlini M, Mabuchi A, Mallard BL, Hairulhisyam N, Akashi-Takamura A, Harper JL, Wheatley AM (2016) 'Delayed liver regeneration in C3H/HeJ mice: Possible involvement of haemodynamic and structural changes in the hepatic microcirculation'. Experimental Physiology, [DOI] [Details]
(2013) 'Concanavalin A-induced hepatitis: Gut derived LPS, intestinal permeability and TLR4'
Mallard BL, Mabuchi A, Akashi-Takamura S, Harper J, Quinlan LR, Wheatley AM (2013) 'Concanavalin A-induced hepatitis: Gut derived LPS, intestinal permeability and TLR4'. Hepatology, 58 (S1):966A-966A [Details]
(2013) 'Concanavalin A-Induced Hepatitis in Mice Is Prevented by Depletion of Gut Bacteria Using Antibiotics'
Beth Mallard, Leo R. Quinlan, Ayako Mabuchi, Antony Wheatley (2013) 'Concanavalin A-Induced Hepatitis in Mice Is Prevented by Depletion of Gut Bacteria Using Antibiotics'. Gastroenterology, 144 (5 Supplement 1) [Details]
(2013) 'Depletion of gut bacteria with antibiotics prevents Concanavalin (Con) A induced hepatitis in mice'
Mallard BL, Quinlan L, Mabuchi A, Wheatley AM (2013) 'Depletion of gut bacteria with antibiotics prevents Concanavalin (Con) A induced hepatitis in mice'. Journal Of Hepatology, 58 (Supplement 1):S145-S145 [Details]
(2009) 'Functional Toll-like receptor 4 (TLR4) signaling pathway in T cells and Kupffer cells is essential for Concanavalin (Con) A-induced hepatitis in mice'
Mallard B; Mabuchi A; Harper J; Wheatley AM (2009) 'Functional Toll-like receptor 4 (TLR4) signaling pathway in T cells and Kupffer cells is essential for Concanavalin (Con) A-induced hepatitis in mice'. Journal Of Hepatology, 50 (S1) [Details]
(2006) 'Short-term suppression of elevated growth hormone concentrations following insulin-like growth factor 1 administration in young adults with type 1 diabetes does not alter glomerular filtration or albumin excretion rates'
Williams RM; Yuen K; White D; Mallard B; Dalton RN; Acerini CL; Dunger DB (2006) 'Short-term suppression of elevated growth hormone concentrations following insulin-like growth factor 1 administration in young adults with type 1 diabetes does not alter glomerular filtration or albumin excretion rates'. Clinical Endocrinology, 65 :439-445 [Details]
(2004) 'Role of hepatic stellate cell/hepatocyte interaction and activation of hepatic stellate cells in the early phase of liver regeneration in the rat'
Mabuchi, A; Mullaney I; Sheard PW; Hessian PA; Mallard BL; Tawadrous MN; Zimmermann A; Senoo H; Wheatley AM (2004) 'Role of hepatic stellate cell/hepatocyte interaction and activation of hepatic stellate cells in the early phase of liver regeneration in the rat'. Journal Of Hepatology, 40 (6):910-916 [Details]

Conference Publications

  Year Publication
(2015) 14th International Congress for Stereology and Image Analysis
NGATIMAN HG, MARLINI M, MALLARD B, DOCKERY P, WHEATLEY AM (2015) Stereological assessment of the intestinal morphology following concanavalin A administration in mice 14th International Congress for Stereology and Image Analysis , pp.1-2 [Details]
(2014) Neuroscience Ireland, Young Neuroscientists Symposium
Killilea M, Flannery L, Kerr DM, Mallard B, Wheatley AM, Roche M (2014) LPS-induced locomotor and inflammatory responding in the stress sensitive WKY rat Neuroscience Ireland, Young Neuroscientists Symposium , pp.45-45 [Details]
(2013) Digestive Diseases Week
Mallard, BL; Quinlan LR; Mabuchi, A; Wheatley, AM (2013) Concanavalin A-Induced Hepatitis in Mice is Prevented by Depletion of Gut Bacteria Using Antibiotics Digestive Diseases Week Orlando, Florida, USA, , 18-MAY-13 - 21-MAY-13 [Details]
(2013) International Liver Congress 2013
Mallard, BL; Quinlan L; Mabuchi, A; Wheatley, AM (2013) Depletion of Gut Bacteria With Antibiotics Prevents Concanavalin (Con) A Induced Hepatitis in Mice International Liver Congress 2013 [Details]
(2013) International Union of Physiological Sciences 2013
Muhamad, M; Mabuchi, A; Mallard, B; Ngatiman, H; Wheatley, AM (2013) Microcirulatory Blood Flow During Liver Regeneration After Partial Hepatectomy in LPS-Sensitive and -Insensitive Mice: An IVFM Study International Union of Physiological Sciences 2013 [Details]
(2013) International Union of Physiologal Sciences 2013
Mallard, BL; Mabuchi, A; Quinlan, L; Wheatley, AM. (2013) Concanavalin A-induced immune-mediated liver injury is attenuated by depletion of gastrointestinal bacteria International Union of Physiologal Sciences 2013 [Details]
(2011) 21st Conference of the Asian Pacific Association for the Study of the Liver
Marlini, M; Mabuchi, A; Mallard, BL, Hairulhisyam, MN, Wheatley, AM (2011) Altered microcirculatory blood flow is associated with delayed liver regeneration in TLR4-mutant mice 21st Conference of the Asian Pacific Association for the Study of the Liver [Details]
(2011) 16th International Symposium on Cells of the Hepatic Sinusoid
Mallard, BL; Mabuchi, A; Akashi-Takamura, S; Harper, J; Quinlan LP; Wheatley, AM (2011) New insights into concanavalin A-induced hepatitis: gut microflora, intestinal permeability, and TLR4 16th International Symposium on Cells of the Hepatic Sinusoid [Details]
(2009) 44th Annual Meeting of the European Association for the Study of the Liver
Mallard B; Mabuchi A; Harper J; Wheatley AM (2009) Functional Toll-like receptor 4 (TLR4) signaling pathway in T cells and Kupffer cells is essential for Concanavalin (Con) A-induced hepatitis in mice 44th Annual Meeting of the European Association for the Study of the Liver [Details]
(2007) The Liver Meeting
Mallard BL; Harper J; Mabuchi A; Wheatley AM (2007) Concanavalin A-induced hepatitis is dependent on Toll-like receptor 4 (TLR4) signaling pathways The Liver Meeting [Details]

Published Reports

  Year Publication
(2013) Concanavalin A-induced hepatitis in mice is prevented by depletion of gut bacteria using antibiotics.
Mallard B, Quinlan LR, Mabuchi A, Wheatley AM (2013) Concanavalin A-induced hepatitis in mice is prevented by depletion of gut bacteria using antibiotics. Gastroenterology 144 (Supplement 1), S939, American Gastoenterological Society. [Details]

Other Journals

  Year Publication
(2016) 'The effects of concanavalin A on the liver and intestinal permeability in C3H/HeN and C3H/HeJ mice'
HAIRULHISYAM N, MALLARD B, MARLINI M, DOCKERY P, WHEATLEY AM (2016) 'The effects of concanavalin A on the liver and intestinal permeability in C3H/HeN and C3H/HeJ mice' Gastroenterology, 150 (4) . [Details]

Conference Contributions

  Year Publication
(2016) 40th Annual Symposium of the Microscopic Society of Ireland,
NGATIMAN HG, MARLINI M, MALLARD B , WHEATLEY AM, DOCKERY P (2016) (2016) Stereological assessment of liver necrosis following concanavalin A administration in mice. [Poster Presentation], 40th Annual Symposium of the Microscopic Society of Ireland, Dublin, Ireland , 12-JUN-16 - 15-JUL-16. [Details]

Meeting

  Year Publication
(2013) DEPLETION OF GUT BACTERIA WITH ANTIBIOTICS PREVENTS CONCANAVALIN (Con) A INDUCED HEPATITIS IN MICE.
Mallard, BL,Quinlan, L,Mabuchi, A,Wheatley, AM (2013) DEPLETION OF GUT BACTERIA WITH ANTIBIOTICS PREVENTS CONCANAVALIN (Con) A INDUCED HEPATITIS IN MICE. Meeting [Details]